M. Martins

N. Zanatta, M. Martins, C. F. Mello, 2004, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

TiO2 nanoparticles coated with deep eutectic solvents: characterization and effect on photodegradation of organic dyes

N. Zanatta, C. Frizzo, M. Martins, 2019, New Journal of Chemistry.

Promotion of 1,3-dipolar cycloaddition between azides and β-enaminones by deep eutectic solvents

N. Zanatta, C. Frizzo, M. Martins, 2016 .

13C NMR Chemical Shifts of Heterocycles: 3∗. Empirical Substituent Effects in 2-Halomethyl-2-hydroxy-tetrahydrofurans and -5,6-tetrahydro-4H-pyrans

M. Martins, 1996 .

13C NMR Chemical Shift of β-Alkoxyvinylketones: II. Empirical Substituent Effects in β-Aryl-β-Methoxyvinyltrihalomethylketones

N. Zanatta, M. Martins, A. Flores, 1995 .

Supramolecular self-assembly and thermodynamic properties of 5-aryl-1-(1,1-dimethylethyl)-1H-pyrazoles in the crystalline state

N. Zanatta, M. Hörner, C. Frizzo, 2019, Journal of Molecular Structure.

[2]Rotaxanes Bearing a Tetralactam Macrocycle: The Role of a Trifurcated Hydrogen Bond in the Crystalline State

Paulo R. S. Salbego, M. Martins, T. Orlando, 2019, European Journal of Organic Chemistry.

Crystallization Mechanisms Applied to Understand the Crystal Formation of Rotaxanes

Paulo R. S. Salbego, N. Zanatta, J. Berná, 2019, European Journal of Organic Chemistry.

Polymorphism in a Rotaxane Molecule: Intra- and Intermolecular Understanding

Paulo R. S. Salbego, N. Zanatta, M. Martins, 2018, Crystal Growth & Design.

Insights on conformation in the solid state: a case study – s-cis and/or s-trans crystallization of 5(3)-aryl-3(5)-carboxyethyl-1-tert-butylpyrazoles

Paulo R. S. Salbego, N. Zanatta, M. Hörner, 2018 .

Conformer Distribution in Rotaxanes Containing Nonsymmetric Threads: A Systematic Approach

Paulo R. S. Salbego, N. Zanatta, J. Berná, 2018, European Journal of Organic Chemistry.

Models for understanding the structural effects on the cation-anion interaction strength of dicationic ionic liquids

Paulo R. S. Salbego, N. Zanatta, M. Villetti, 2018 .

Competition between the donor and acceptor hydrogen bonds of the threads in the formation of [2]rotaxanes by clipping reaction

N. Zanatta, J. Berná, C. Frizzo, 2017 .

Preparation of new 2-amino- and 2,3-diamino-pyridine trifluoroacetyl enamine derivatives and their application to the synthesis of trifluoromethyl-containing 3H-pyrido[2,3-b][1,4] diazepinols

N. Zanatta, R. Lourega, M. Martins, 2008 .

Synthesis, antimicrobial activity, and QSAR studies of furan-3-carboxamides.

N. Zanatta, S. H. Alves, M. Martins, 2007, Bioorganic & medicinal chemistry.

The potential antidepressant-like effect of imidazoline I2 ligand 2-BFI in mice

M. Martins, J. Ferreira, G. Trevisan, 2012, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Ionic liquids in heterocyclic synthesis.

N. Zanatta, C. Frizzo, M. Martins, 2008, Chemical reviews.

Structural and thermodynamic properties of new pyrazolo[3,4-d]pyridazinones

M. Villetti, R. Claramunt, D. Sanz, 2013 .

Update 1 of: Ionic liquids in heterocyclic synthesis.

N. Zanatta, C. Frizzo, A. Tier, 2014, Chemical reviews.

Intramolecular cyclization of N-propargylic β-enaminones catalyzed by silver

N. Zanatta, C. Frizzo, M. Martins, 2013 .

Haloacetylated enol ethers. 9. Synthesis of 4-trifluoromethyl-2-methyl[phenyl]pyrimidines and tetrahydro derivatives

N. Zanatta, M. Martins, H. Bonacorso, 1998 .

Haloacetylated enol ethers 10. Condensation of β-alkoxyvinyl trifluoromethyl ketones with thiosemicarbazide. Synthesis of new trifluoromethyl 4,5-dihydro-1H-1-pyrazolethiocarboxyamides

N. Zanatta, J. A. Naue, M. Martins, 1998 .

Synthesis and photophysical properties of trichloro(fluoro)-Substituted 6-(3-oxo-1-(alk-1-en-1-yl)amino)coumarins and their 2,2-Difluoro-2H-1,3,2-oxazaborinin-3-ium-2-uide heterocycles

N. Zanatta, B. Iglesias, M. Martins, 2020 .

New 2-(aryl/heteroaryl)-6-(morpholin-4-yl/pyrrolidin-1-yl)-(4-trifluoromethyl)quinolines: synthesis via Buchwald–Hartwig amination, photophysics, and biomolecular binding properties

N. Zanatta, B. Iglesias, C. Frizzo, 2018 .

Synthesis and antimicrobial screening of 2-alkyl(aryl)-7-chloro-6-fluoro-4-(trifluoromethyl)-quinolines and their phenylacetylene derivatives, promoted by Sonogashira cross-coupling reaction

N. Zanatta, S. H. Alves, C. Frizzo, 2018 .

Cycloaromatization Reaction of 4‐Alkoxy‐1,1,1‐trifluoroalk‐3‐en‐2‐ones with 2,6‐Diaminotoluene: The Unexpected Regioselective Synthesis of 2,4,7,8‐Tetrasubstituted Quinolines

N. Zanatta, M. Martins, H. Bonacorso, 2013 .

Ultrasound promoted the synthesis of N-propargylic β-enaminones.

N. Zanatta, C. Frizzo, M. Martins, 2012, Ultrasonics sonochemistry.

An efficient and regiospecific preparation of trifluoromethyl substituted 4‐( 1H‐pyrazol‐1 ‐yl)‐7‐chloroquinolines

N. Zanatta, M. B. Costa, M. Martins, 2005 .

Solution and Solid-State Optical Properties of Trifluoromethylated 5-(Alkyl/aryl/heteroaryl)-2-methyl-pyrazolo[1,5-a]pyrimidine System

N. Zanatta, B. Iglesias, C. Frizzo, 2022, Photochem.

Haloacetylated Enol Ethers: a Way Out for the Regioselective Synthesis of Biologically Active Heterocycles

N. Zanatta, M. Martins, H. Bonacorso, 2021, European Journal of Organic Chemistry.

Regioselective synthesis and through-space 13C–19F spin–spin coupling NMR of new tetracyclic 3-(trifluoromethyl)-spiro(chromen[4,3-c]pyrazole-4,1′-cycloalkanes)

N. Zanatta, C. Frizzo, A. Tier, 2014 .

ANRORC rearrangement in tetrahydro-2H-chromenones. Synthesis and structural assignment by NMR, MS, X-ray and DFT calculations of 2-[3(5)-trifluoromethyl-1H-pyrazol-4-yl)arylmethyl]cyclohexenones and derivatives

N. Zanatta, M. Martins, H. Bonacorso, 2013 .

Chemoselective O-Alkylation of 4-(Trifluoromethyl)pyrimidin-2(1H)-ones Using 4-(Iodomethyl)pyrimidines

N. Zanatta, L. Wessjohann, M. Martins, 2022, ACS omega.

Substituent-Driven Selective N-/O-Alkylation of 4-(Trihalomethyl)pyrimidin-2(1H)-ones Using Brominated Enones.

N. Zanatta, L. Wessjohann, M. Martins, 2022, The Journal of organic chemistry.

Convergent procedure for the synthesis of trifluoromethyl-containing N-(pyridinyl-triazolyl)pyrimidin-2-amines

N. Zanatta, M. Martins, H. Bonacorso, 2010 .

Structural Studies of 2-Methyl-7-substituted Pyrazolo[1,5-a]pyrimidines

Mara R. B. Marzari, J. Elguero, I. Alkorta, 2010 .

2-Trifluoroacetyl-1-methoxycycloalkenes: A convenient precursor for the synthesis of geminated polymethylene trifluoromethyl substituted heterocycles

N. Zanatta, M. B. Costa, M. Martins, 2009 .

Convergent synthesis and cruzain inhibitory activity of novel 2-(N'-benzylidenehydrazino)-4-trifluoromethyl-pyrimidines.

N. Zanatta, A. Andricopulo, M. Martins, 2008, Bioorganic & medicinal chemistry.

Comparative Study of the Chemoselectivity and Yields of the Synthesis of N-Alkyl-4-(trihalomethyl)-1H-pyrimidin-2-ones

N. Zanatta, M. Martins, H. Bonacorso, 2008 .

Synthesis and structural study of a new series of 2‐methylsulfanyl‐tetrahydropyrimidines from β‐alkoxyvinyl trihalomethyl ketones

N. Zanatta, R. Burrow, M. Martins, 2008 .

Synthesis of New 2-(5-Aryl-3-styryl-4,5-dihydro-1H-pyrazol-1-yl)-4- (trifluoromethyl)pyrimidines

R. Burrow, M. Martins, A. Flores, 2006 .

Synthesis of Tetrahydro‐2(1H)quinazolinones, Cyclopenta[d]‐2(1H)pyrimidinones, and Their Thioxo Analogs from 2‐Trifluoroacetyl‐1‐methoxycycloalkenes

N. Zanatta, M. B. Costa, M. Martins, 2005 .

Synthesis of Alkyl-, Aryl- and Heteroaryl-Substituted 2-[3-Oxo-2,3-dihydro-1H-pyrazol-2-yl]-6(4)-trifluoromethylpyrimidines from β-Alkoxyvinyl Trifluoromethyl Ketones

N. Zanatta, M. Martins, H. Bonacorso, 2005 .

Cyclocondensation reaction of 4-aryl-4-methoxy-1,1,1-trifluoro-3-buten-2-ones with urea

N. Zanatta, M. Martins, H. Bonacorso, 2003 .

Regiospecific synthesis of 4-alkoxy and 4-amino substituted 2-trifluoromethyl pyrroles.

N. Zanatta, L. Wessjohann, P. Schneider, 2006, The Journal of organic chemistry.

Haloacetylated enol ethers. 7 . Synthesis of 3-aryl-5-trihalomethylisoxazoles and 3-aryl-5-hydroxy-5-trihalomethyl-4,5-dihydroisoxazoles†

N. Zanatta, M. Martins, H. Bonacorso, 1996 .

Synthesis of 1,1,1-trihalo-4-methoxy-4-[2-heteroaryl]-3-buten-2-ones, the corresponding butan-1,3-dione and azole derivatives

N. Zanatta, M. Martins, A. Flores, 2002 .

Trihaloacetylated enol ethers : general synthetic procedure and heterocyclic ring closure reactions with hydroxylamine

P. Fischer, M. Martins, A. Colla, 1991 .

Deep eutectic solvent mediated synthesis of thiomethyltriazolo[1,5-a]pyrimidines

N. Zanatta, C. Frizzo, M. Martins, 2016 .

One‐pot synthesis of N2‐aminoprotected 6‐substituted and cycloalka[d] 4‐trifluoromethyl‐2‐acetylaminopyrimidines

N. Zanatta, M. Martins, H. Bonacorso, 2008 .

A Convenient Synthesis of 5- and 6-Substituted 2-Phenyl-3H-pyrimidin-4-ones

N. Zanatta, R. Lourega, M. Martins, 2008 .

Hypothermic and antipyretic effects of 3-methyl- and 3-phenyl-5-hydroxy-5-trichloromethyl-4,5-dihydro-1H-pyrazole-1-carboxyamides in mice.

N. Zanatta, M. Martins, C. F. Mello, 2002, European journal of pharmacology.

Streamlined Synthesis of 6-((1H-1,2,3-Triazol-4-yl)methyl)-1H-pyrrolo [3,4-d]pyridazin-1-one System via Sequential N-Alkylation, CuAAC, and [4 + 2] Cyclization Reactions

N. Zanatta, C. Frizzo, M. Martins, 2019, Journal of the Brazilian Chemical Society.

Chemo- and regioselective reactions of 5-bromo enones/enaminones with pyrazoles.

N. Zanatta, C. Frizzo, M. Martins, 2019, Organic & biomolecular chemistry.

Simultaneous regioselective synthesis of trifluoromethyl-containing 1,7-phenanthrolines and quinolines from cyclocondensation reaction of N,N'-bis(oxotrifluoroalkenyl)-1,3-phenylenediamines

N. Zanatta, M. Martins, H. Bonacorso, 2011 .

Regioselectively controlled synthesis of 3(5)-(trifluoromethyl)pyrazolylbenzenesulfonamides and their effects on a pathological pain model in mice.

N. Zanatta, O. N. de Souza, S. M. Oliveira, 2015, European journal of medicinal chemistry.

New strategy for the regioselective synthesis of 1-phenyl-3-trifluoromethyl-1H-pyrazoles

N. Zanatta, M. Martins, H. Bonacorso, 2013 .

17 Ionic Liquids : Applications in Heterocyclic Synthesis

C. Frizzo, M. Martins, D. N. Moreira, 2014 .

Ionic Liquids: Applications in Heterocyclic Synthesis

C. Frizzo, M. Martins, D. N. Moreira, 2011 .

An efficient solvent-free synthesis of NH-pyrazoles from β-dimethylaminovinylketones and hydrazine on grinding

Mara R. B. Marzari, N. Zanatta, M. Martins, 2010 .

4-Alkoxy-1,1,1-trichloro-3-alken-2-ones: Preparation and Applications in Heterocyclic Synthesis

N. Zanatta, M. Martins, A. Sinhorin, 2004 .

Design and microwave-assisted synthesis of 5-trifluoromethyl-4,5-dihydro-1H-pyrazoles: novel agents with analgesic and anti-inflammatory properties.

N. Zanatta, R. Burrow, A. H. de Souza, 2008, European journal of medicinal chemistry.

Synthesis of N-substituted 6-trifluoromethyl-1,3-oxazinanes

N. Zanatta, M. Martins, H. Bonacorso, 2005 .

Synthesis and photophysical, thermal and antimycobacterial properties of novel 6-amino-2-alkyl(aryl/heteroaryl)-4-(trifluoromethyl) quinolines

Paulo R. S. Salbego, N. Zanatta, L. A. Basso, 2019, New Journal of Chemistry.

Cyanoacetylazoles and salicylic aldehydes promoting the synthesis of new trifluoromethyl-substituted azolecarbonyl-2H-chromen-2-ones through the Knoevenagel condensation reaction

N. Zanatta, C. Frizzo, M. Martins, 2015 .

New solventless and metal-free synthesis of the antiepileptic drug 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide (Rufinamide) and analogues

Marcos A. P. Martins, N. Zanatta, M. Martins, 2015 .

Ionic liquid/HCl catalyzed synthesis of 4-(trifluoromethyl)-2(1H)-pyrimidinones

Mara R. B. Marzari, C. Frizzo, M. Martins, 2014, Monatshefte für Chemie - Chemical Monthly.

Resourceful synthesis of pyrazolo[1,5-a]pyrimidines under ultrasound irradiation.

Mara R. B. Marzari, N. Zanatta, C. Frizzo, 2013, Ultrasonics sonochemistry.

Evaluation of the synthesis of 1-(pentafluorophenyl)-4,5-dihydro-1H-pyrazoles using green metrics

Mara R. B. Marzari, Pablo Machado, Marcos A. P. Martins, 2013, Monatshefte für Chemie - Chemical Monthly.

An E-factor minimized solvent-free protocol for the preparation of 4,5-dihydro-5-(trifluoromethyl)-1H-pyrazoles

Mara R. B. Marzari, C. Frizzo, M. Martins, 2011 .

Synergic Effects of Ionic Liquid and Microwave Irradiation in Promoting Trifluoromethylpyrazole Synthesis

Mara R. B. Marzari, N. Zanatta, C. Frizzo, 2011 .

Efficient and highly regioselective synthesis of ethyl 1-(2,4-dichlorophenyl)-1H-pyrazole-3-carboxylates under ultrasound irradiation.

N. Zanatta, M. Martins, H. Bonacorso, 2011, Ultrasonics sonochemistry.

Supramolecular structure of enaminones in solid-state

Mara R. B. Marzari, N. Zanatta, C. Frizzo, 2010 .

Synthesis of New 1,1'-Carbonyl-bis[3-aryl(heteroaryl)-5-(trihalomethyl)-1H-pyrazoles] and Trifluoromethyl Derivatives through Ring-Opening Reactions

N. Zanatta, M. Martins, H. Bonacorso, 2010 .

X-ray structure, semi-empirical MO calculations and π-electron delocalization of 1-cyanoacetyl-5-trifluoromethyl-5-hydroxy-4,5-dihydro-1H-pyrazoles

Mara R. B. Marzari, N. Zanatta, C. Frizzo, 2010 .

Straightforward microwave‐assisted synthesis of 1‐carboxymethyl‐5‐trifluoromethyl‐5‐hydroxy‐4,5‐dihydro‐1H‐pyrazoles under solvent‐free conditions

N. Zanatta, C. Frizzo, M. Martins, 2010 .

Molecular structure of pyrazolo[1,5-a]pyrimidines: X-ray diffractometry and theoretical study

C. Frizzo, M. Martins, P. T. Campos, 2009 .

Ionic liquid as catalyst in the synthesis of N-alkyl trifluoromethyl pyrazoles

Mara R. B. Marzari, N. Zanatta, E. Guarda, 2009 .

Highly Chemoselective Synthesis of 6-Alkoxy-1-alkyl(aryl)-3-trifluoroacetyl-1,4,5,6-tetrahydropyridines and 1-Alkyl(aryl)-6-amino-3-trifluoroacetyl-1,4,5,6-tetrahydropyridines

N. Zanatta, M. Martins, H. Bonacorso, 2009 .

Experimental and calculated structural parameters of 5-trihalomethyl-4,5-dihydro-1H-pyrazole derivatives, novel analgesic agents

N. Zanatta, M. Martins, H. Bonacorso, 2009 .

Simplified Approach to the Regiospecific Synthesis of Trichloromethylpyrazolines Using Microwave Irradiation

N. Zanatta, Paulo I. R. Muraro, C. Frizzo, 2008 .

An efficient synthesis of 1-cyanoacetyl-5-halomethyl-4,5-dihydro-1H-pyrazoles in ionic liquid

N. Zanatta, C. Frizzo, M. Martins, 2008 .

Reaction of β-dimethylaminovinyl ketones with hydroxylamine: A simple and useful method for synthesis of 3- and 5-substituted isoxazoles

N. Zanatta, M. Martins, H. Bonacorso, 2008 .

The regiospecific ω-bromination of 2-trichloroacetylcycloalkanones

N. Zanatta, M. Martins, H. Bonacorso, 2008 .

2-Methyl-5-(4-tolyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine

Clarissa P. Frizzo, Patrick T. Campos, Mara R. B. Marzari, 2007, Acta crystallographica. Section E, Structure reports online.

A simple one-pot synthesis of 3-alkoxy-3-cyanocarboxylic acids: a rapid entry to new GABA derivatives

N. Zanatta, L. Jank, M. Martins, 2007 .

Synthesis of 1,1,1-trichloro[fluoro]-3-alken-2-ones using ionic liquids

N. Zanatta, E. Guarda, C. Frizzo, 2007 .

Indium(III) bromide catalyzed one-pot synthesis of trichloromethylated tetrahydropyrimidinones

N. Zanatta, M. Martins, Yaofeng Yuan, 2004 .

Synthesis of β-enaminones by ionic liquid catalysis: A one-pot condensation under solvent-free conditions

Mara R. B. Marzari, N. Zanatta, C. Frizzo, 2008 .

Synthesis and Characterization of Some Novel 2-(Trifluoromethyl)pyrimido[1,2-a]benzimidazoles and Pyrimido[1,2-a]benzimidazol-2H)-ones of Biological Interest

N. Zanatta, A. Echevarria, M. Martins, 2006 .

Antipyretic and antioxidant activities of 5-trifluoromethyl-4,5-dihydro-1H-pyrazoles in rats.

N. Zanatta, M. Martins, C. F. Mello, 2010, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

4-Trichloroacetyl-1,2,3-triazoles: A versatile building block for rapid assessment of carbohydrazides and rufinamide derivatives

N. Zanatta, M. Martins, H. Bonacorso, 2017 .

Organoallylaluminum Reagents Promote Easy Access to Trihalomethyl Triazolyl Homoallylic Alcohols Analogous to Rufinamide.

N. Zanatta, M. Martins, H. Bonacorso, 2014 .

Organoallylaluminum reagents promote easy access to trihalomethyl triazolyl homoallylic alcohols analogous to rufinamide

N. Zanatta, M. Martins, H. Bonacorso, 2014 .

Synthesis of 1H-1,2,3-triazoles—Rufinamide analogs by 1,3-dipolar cycloaddition and eletrocyclization reactions of trifluoroacetyl enolethers under thermal solventless conditions

N. Zanatta, M. Martins, H. Bonacorso, 2013 .

Straightforward method for regioselective reduction of 3-acyl-substituted 2-(trifluoromethyl)-2H-chromen-5-one and chromane scaffolds in NaBH4/ethanol medium

N. Zanatta, M. Martins, H. Bonacorso, 2013 .

A convenient one-pot synthesis of 5-carboxyisoxazoles: trichloromethyl group as a carboxyl group precursor

N. Zanatta, M. Martins, A. Sinhorin, 2000 .

A pyrazolyl-thiazole derivative causes antinociception in mice.

N. Zanatta, R. Lourega, A. H. de Souza, 2006, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Efficient entry to trifluoromethyl substituted chromanes from oxidative aromatization of tetrahydro-2H-chromen-5(6H)-ones using iodine/alcohol with conventional and microwave methods

N. Zanatta, M. Martins, H. Bonacorso, 2012 .

Chemoselective fluorination of 2-hydroxy-3,4,7,8-tetrahydro-2H-chromen-5(6H)-ones using DAST

N. Zanatta, M. Martins, H. Bonacorso, 2011 .

The first application of 4-alkoxy-1,1,1-trifluoroalk-3-en-2-ones in a three-component condensation protocol for the synthesis of 3-acyl-4-aryl-2-(trifluoromethyl)-2-hydroxy-3,4,7,8-tetrahydro-2H-chromen-5(6H)-ones

N. Zanatta, M. Martins, H. Bonacorso, 2011 .

Synthesis of New Fluorine‐Containing Dihydrobenzo[c]acridines from Trifluoroacetyl Dihydronaphthalene and Substituted Anilines.

N. Zanatta, M. B. Costa, M. Martins, 2006 .

Thermodynamic properties of the aggregation behavior of a dicationic ionic liquid determined by different methods

Paulo R. S. Salbego, M. Villetti, C. Frizzo, 2016 .

Trifluoromethyl-containing pyrazolinyl ( p -tolyl) sulfones: The synthesis and structure of promising antimicrobial agents

N. Zanatta, S. H. Alves, R. Lourega, 2006 .

Efficient synthesis of 6-aryl-4-trifluoromethyl/ethoxycarbonyl-2 H -pyran-2-ones through self-condensation of penta-2,4-dienenitriles

N. Zanatta, M. Martins, H. Bonacorso, 2018 .

Ullmann-type copper-catalyzed coupling amination, photophysical and DNA/HSA-binding properties of new 4-(trifluoromethyl)quinoline derivatives

N. Zanatta, B. Iglesias, M. Martins, 2019, Journal of Fluorine Chemistry.

A novel, potent, oral active and safe antinociceptive pyrazole targeting kappa opioid receptors

N. Zanatta, J. Calixto, A. Boligon, 2013, Neuropharmacology.

Novel 4,5-bis(trifluoromethyl)-1H-pyrazoles through a concise sequential iodination-trifluoromethylation reaction

N. Zanatta, M. Martins, H. Bonacorso, 2019, Tetrahedron Letters.

Sequential one-pot three-step synthesis of polysubstituted 4-(5-(trifluoromethyl)-1H-pyrazol-4-yl)-1H-1,2,3-triazole systems

N. Zanatta, C. Frizzo, M. Martins, 2017 .

New 4-fluoroalkyl substituted N-phenylpyrazoles: Synthesis promoted by DAST and multinuclear NMR analysis

N. Zanatta, M. Martins, H. Bonacorso, 2015 .

Structural improvement of compounds with analgesic activity: AC-MPF4, a compound with mixed anti-inflammatory and antinociceptive activity via opioid receptor

S. M. Oliveira, M. Martins, J. Ferreira, 2015, Pharmacology Biochemistry and Behavior.

New one-pot, efficient, and regioselective method for the synthesis of 3-Trifluoromethyl-1H-1-phenylpyrazoles and alkyl 3-carboxylate analogs

N. Zanatta, M. Martins, H. Bonacorso, 2012 .

Effect of 5-trifluoromethyl-4,5-dihydro-1H-pyrazoles on chronic inflammatory pain model in rats.

N. Zanatta, M. Martins, C. F. Mello, 2009, European journal of pharmacology.

Antinociceptive effect of a novel tosylpyrazole compound in mice.

N. Zanatta, R. Lourega, S. M. Oliveira, 2009, Basic & clinical pharmacology & toxicology.

Antinociceptive action of 4-methyl-5-trifluoromethyl-5-hydroxy-4, 5-dihydro-1H-pyrazole methyl ester in models of inflammatory pain in mice.

N. Zanatta, C. Drewes, S. M. Oliveira, 2008, Life sciences.

Design and Microwave‐Assisted Synthesis of 5‐Trifluoromethyl‐4,5‐dihydro‐1H‐pyrazoles: Novel Agents with Analgesic and Antiinflammatory Properties.

M. Martins, 2008 .

Alpha 2-adrenoceptors and 5-HT receptors mediate the antinociceptive effect of new pyrazolines, but not of dipyrone.

N. Zanatta, M. Martins, M. R. Fighera, 2004, European journal of pharmacology.

Microwave-assisted synthesis of 5-trichloromethyl substituted 1-phenyl-1H-pyrazoles and 1,2-dimethylpyrazolium chlorides

N. Zanatta, S. Moura, M. Martins, 2003 .

Microwave assisted synthesis of 5-hydroxy-5-trichloromethyl-4,5-dihydroisoxazoles

N. Zanatta, M. Martins, A. Sinhorin, 2002 .

Trifluoroacetylation of unsymmetrical ketone acetals. A convenient route to obtain alkyl side chain trifluoromethylated heterocycles

N. Zanatta, R. Lourega, M. Martins, 1999 .

Regiospecific acylation of acetals. A convenient method to obtain β-methoxyvinyl trichloromethyl ketones

N. Zanatta, M. Martins, H. Bonacorso, 1999 .

Synthesis of Methylene-Bridged Trifluoromethyl Azoles Using 5-(1,2,3-Triazol-1-yl)enones

N. Zanatta, L. Wessjohann, M. Martins, 2021, Synthesis.

The Wonderful World of β‐Enamino Diketones Chemistry

N. Zanatta, M. Martins, H. Bonacorso, 2020 .

Trends in mass spectrum fragmentation of pyrazoles

N. Zanatta, Keli Maiara Wust, M. Martins, 2019 .

Straightforward and Regiospecific Synthesis of Pyrazole-5-carboxylates from Unsymmetrical Enaminodiketones.

N. Zanatta, M. Martins, H. Bonacorso, 2008 .

Novel 2-phenyl-6-phenylethynyl-4-(trifluoromethyl)quinolines: Synthesis by Sonogashira cross-coupling reaction and their evaluation as liquid crystals

N. Zanatta, C. Frizzo, M. Martins, 2019, Journal of Molecular Liquids.

Efficient approach for regioselective synthesis of new trifluoromethyl-substituted spirotetracyclic isoxazolines and isoxazoles

N. Zanatta, C. Frizzo, M. Martins, 2017 .

Synthesis, biological evaluation and molecular docking study of 7-amine-spiro[chromeno[4,3-b]quinoline-6,1′-cycloalkanes] as new tacrine hybrids

N. Zanatta, P. Nogara, J. Rocha, 2015 .

Investigating ESIPT and donor-acceptor substituent effects on the photophysical and electrochemical properties of fluorescent 3,5-diaryl-substituted 1-phenyl-2-pyrazolines.

N. Zanatta, B. Iglesias, C. Frizzo, 2021, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

Synthesis and structure of new trichloromethyl-β- diketones : 5-trichloromethylisoxazole and 5- isoxazolecarboxylic acid derivatives

N. Zanatta, M. Hörner, S. Moura, 2005 .

Ultrasound irradiation promotes the synthesis of new 1,2,4-triazolo[1,5-a]pyrimidine.

Mara R. B. Marzari, N. Zanatta, C. Frizzo, 2014, Ultrasonics sonochemistry.

From Renewable Levulinic Acid to a Diversity of 3-(Azol-3-yl)Propanoates

M. Martins, Lucas Pizzuti, A. Flores, 2014 .

Synthesis of Highly Functionalized 4-Amino-2-(trifluoromethyl)-1H-pyrroles

N. Zanatta, M. Martins, H. Bonacorso, 2021, Synthesis.

Synthesis of N-Pyrrolyl(furanyl)-Substituted Piperazines, 1,4-Dizepanes, and 1,4-Diazocanes.

N. Zanatta, C. Frizzo, M. Martins, 2019, The Journal of organic chemistry.

General Pathway for a Convenient One-Pot Synthesis of Trifluoromethyl-Containing 2-amino-7-alkyl(aryl/heteroaryl)-1,8-naphthyridines and Fused Cycloalkane Analogues

N. Zanatta, M. Martins, H. Bonacorso, 2011, Molecules.

Synthesis and characterization of new trifluoromethyl substituted 3‐ethoxycarbonyl‐ and 3‐pyrimidin‐2‐yl)‐(1,2,3)‐oxathiazinane‐S‐oxides

N. Zanatta, M. Martins, H. Bonacorso, 2008 .

Regioselective synthesis, biological evaluation, and molecular docking of dihydropyrimidin‐4‐ols as acetylcholinesterase inhibitors

N. Zanatta, Jonas D S Serres, V. Morsch, 2017, Chemical biology & drug design.

Ionic Liquid/HCl Catalyzed Synthesis of 4‐(Trifluoromethyl)‐2(1H)‐pyrimidinones.

Mara R. B. Marzari, C. Frizzo, M. Martins, 2014 .

Ionic Liquids Promoted the C-Acylation of Acetals in Solvent-free Conditions

Mara R. B. Marzari, N. Zanatta, E. Guarda, 2009 .

Synthesis of 6-(2-furyl) and 6-(2-thienyl)-4-trifluoromethylpyrimidinones and pyrimidines from 4-(2-heteroaryl)-4-methoxy-1,1,1-trifluoro-3-buten-2-ones

N. Zanatta, M. Martins, Lucas Pizzuti, 2007 .

Heterocyclization of ω-Bromo-2-trichloroacetyl Cycloalkanones to Isoxazole Derivatives

M. Martins, A. Flores, L. Piovesan, 2009 .

Haloacetylated Enol Ethers, 19: Synthesis of 3-(2-Thienyl)- and 3-(2-Furyl)-5-trihalomethyl Substituted Azoles

N. Zanatta, M. Martins, H. Bonacorso, 2005 .

Regiospecific synthesis of new non-condensed heteropolycyclic systems from beta-heteroaryl-beta-methoxyvinyl trihalomethyl ketones

N. Zanatta, M. B. Costa, M. Martins, 2005 .

Ionic liquid promoted cyclocondensation reactions to the formation of isoxazoles, pyrazoles and pyrimidines

N. Zanatta, C. Frizzo, M. Martins, 2010 .

Reaction of β-Dimethylaminovinyl Ketones with Hydroxylamine: A Simple and Useful Method for Synthesis of 3- and 5-Substituted Isoxazoles.

N. Zanatta, M. Martins, H. Bonacorso, 2008 .

Haloacetylated enol ethers. 5 [5]. Heterocyclic ring closure reactions of β‐alkoxyvinyl dichloromethyl ketones with hydroxylamine

N. Zanatta, M. Martins, H. Bonacorso, 1995 .

Chemoselective synthesis of 6-amino(alkoxy)-1,4,5,6-tetrahydropyridines from cyclic β-alkoxyvinyl α-ketoester

N. Zanatta, M. Martins, H. Bonacorso, 2019 .

In vitro and in silico analysis of the efficiency of tetrahydropyridines as drug efflux inhibitors in Escherichia coli.

K. Machado, N. Zanatta, D. Ramos, 2017, International journal of antimicrobial agents.

Highly Chemoselective Synthesis of 6‐Alkoxy‐1‐alkyl(aryl)‐3‐trifluoroacetyl‐1,4,5,6‐tetrahydropyridines and 1‐Alkyl(aryl)‐6‐amino‐3‐trifluoroacetyl‐1,4,5,6‐tetrahydropyridines.

N. Zanatta, M. Martins, H. Bonacorso, 2009 .

Convenient synthesis of 3-aminomethylenedihydrofuran-2-ones

N. Zanatta, M. Martins, H. Bonacorso, 2003 .

Synthesis of hydroxypyrazoles and 1-methyl-3-isoxazolones via haloform reactions

N. Zanatta, M. Martins, A. Flores, 2002 .

Haloacetylated enol ethers. 8 [12]. Reaction of β-alkoxyvinyl trihalomethyl ketones with guanidine hydrochloride. Synthesis of 4-trihalomethyl-2-aminopyrimidines

N. Zanatta, M. Martins, H. Bonacorso, 1997 .

An efficient and regioselective synthesis of 1,1′-oxalylbis[3-(alkyl/aryl/heteroaryl)-5-(trihalomethyl)-1H-pyrazoles] from 4-alkoxy-1,1,1-trihaloalk-3-en-2-ones

N. Zanatta, M. Martins, H. Bonacorso, 2011 .

Synthesis of New 1,1′‐Carbonyl‐bis[3‐aryl(heteroaryl)‐5‐(trihalomethyl)‐1H‐pyrazoles] and Trifluoromethyl Derivatives Through Ring‐Opening Reactions.

N. Zanatta, M. Martins, H. Bonacorso, 2011 .

β-Alkoxyvinyl trifluoromethyl ketones as efficient precursors for the one-pot synthesis of bis-(4,5-dihydro-1H-pyrazol-1-yl)methanones and 1H-pyrazolyl-1-carbohydrazides

N. Zanatta, M. Martins, H. Bonacorso, 2009 .

Regiospecific one-pot synthesis of new trifluoromethyl substituted heteroaryl pyrazolyl ketones

N. Zanatta, M. B. Costa, M. Martins, 2005 .

Reactions of β-methoxyvinyl trifluoromethyl ketones with 2-pyridinecarboxamidrazone

N. Zanatta, M. B. Costa, M. Martins, 2003 .

5-Trifluoromethyl-1,2-dimethyl-1H-pyrazolium chlorides: synthesis and , , and NMR chemical shifts

N. Zanatta, M. Martins, H. Bonacorso, 2002 .

Sonochemical heating profile for solvents and ionic liquid doped solvents, and their application in the N-alkylation of pyrazoles.

N. Zanatta, C. Frizzo, M. Martins, 2016, Ultrasonics sonochemistry.

2-methyl-7-substituted pyrazolo[1,5-a]pyrimidines: highly regioselective synthesis and bromination

N. Zanatta, C. Frizzo, M. Martins, 2009 .

Microwave-Assisted Regiospecific Synthesis of 2-Trifluoromethyl-7- Trihalomethylated Pyrazolo[1,5-a]Pyrimidines

N. Zanatta, Daniel J. Emmerich, M. Martins, 2006 .

Efficient microwave-assisted synthesis of 1-aryl-4-dimethylamino methyleno-pyrrolidine-2,3,5-triones

N. Zanatta, C. Frizzo, M. Martins, 2012 .

Straightforward Microwave-Assisted Synthesis of 1-Carboxymethyl-5-trifluoromethyl-5-hydroxy-4,5-dihydro-1H-pyrazoles under Solvent-Free Conditions.

N. Zanatta, C. Frizzo, M. Martins, 2010 .

Regiospecific Synthesis of 5-Trichloromethyl-1H-Pyrazole and 1HPyrazole-5-Carboxylic Ester Derivatives

E. Pinto, S. Moura, M. Martins, 2008 .

Reaction of β-alkoxyvinyl halomethyl ketones with cyanoacetohydrazide

N. Zanatta, C. Frizzo, M. Martins, 2008 .

A solvent-free synthesis of beta-enamino trihalomethyl ketones

Mara R. B. Marzari, N. Zanatta, C. Frizzo, 2007 .

Microwave-Assisted Synthesis of Novel 5-Trichloromethyl-4,5-dihydro-1H-1-pyrazole Methyl Esters under Solvent Free Conditions

N. Zanatta, S. Moura, M. Martins, 2006 .

One‐pot synthesis of aryl and heteroaroyl‐substituted hydroxypyrazolines from the reactions of β‐alkoxyvinyl trichloromethyl ketones with heteroarylhydrazides

N. Zanatta, M. B. Costa, M. Martins, 2006 .

Molecular Structure of Heterocycles: 3. Semiempirical MO Calculations and Karplus-Type Dihedral Angle Dependence for the Coupling Constant Relationship of Some 4,5-Dihydro-5-Hydroxy- 5(3)-Halomethylisoxazoles

N. Zanatta, M. Martins, A. Flores, 1998 .

Haloacetylated enol ethers. 2. Synthesis of 5-trifluoromethylpyrazoles†

M. Martins, Günter Clar, Mara E. F. Braibante, 1993 .

Brominated β-Alkoxyvinyl Trihalomethyl Ketones as Promising Synthons in Heterocyclic Synthesis

N. Zanatta, M. Martins, H. Bonacorso, 2020 .

An Efficient Two‐Step Synthesis of New 5‐Substituted‐1H‐tetrazoles of Biological Interest

N. Zanatta, M. Martins, H. Bonacorso, 2013 .

Synthesis and structural study of N‐methyl‐2‐methylthiopyrimidine derivatives from trihalomethylated enones

N. Zanatta, M. Martins, H. Bonacorso, 2010 .

A Simple One‐Pot Synthesis of 3‐Alkoxy‐3‐cyanocarboxylic Acids: A Rapid Entry to New GABA Derivatives.

N. Zanatta, L. Jank, M. Martins, 2007 .

Design and Synthesis of Novel Trichloromethylated N-Azolylmethyl-1H-pyrimidin-2-ones and Related N-Methylenaminones

N. Zanatta, M. Martins, H. Bonacorso, 2005 .

One‐Pot Synthesis of Pyrazole‐5(3)‐carboxyamides

N. Zanatta, Daniel J. Emmerich, M. Martins, 2004 .

Convenient synthesis of furan-3-carboxylic acid and derivatives

N. Zanatta, M. Martins, H. Bonacorso, 2004 .

1,1,1-Trichloro-4,4-diethoxy-3-buten-2-one and its trichloroacetylacetate derivatives: Synthesis and applications in regiospecific preparation of azoles

N. Zanatta, S. Moura, M. Martins, 2003 .

β-Alkoxyvinyl trichloromethyl ketones as N-heterocyclic acylating agent. A new access to 5H-thiazolo[3,2-a]pyrimidin-5-ones

N. Zanatta, R. Lourega, M. Martins, 2002 .

One-Pot Synthesis of a New Series of 3-Alkoxy-5-hydroxy-5-trifluoromethylpyrrolidin-2-ones from 1,1,1-Trifluoro-4-alkoxyalk-3-en-2-ones

N. Zanatta, Simone Beux, M. Martins, 2002 .

Synthesis of 4‐(trihalomethyl)dipyrimidin‐2‐ylamines from β‐alkoxy‐α,β‐unsaturated trihalomethyl ketones

N. Zanatta, M. Martins, H. Bonacorso, 2002 .

Indium(III) Bromide Catalyzed One-Pot Synthesis of Trichloromethylate Tetrahydropyrimidinones.

N. Zanatta, M. Martins, Yaofeng Yuan, 2005 .

Solvent‐free route to β‐enamino dichloromethyl ketones and application in the synthesis of novel 5‐dichloromethyl‐1H‐pyrazoles

N. Zanatta, C. Frizzo, M. Martins, 2009 .

Reactivity of trifluoromethyl-tetrazolo[1,5-a]pyrimidines in click chemistry and hydrogenation

N. Zanatta, C. Afonso, C. Frizzo, 2022, Journal of Fluorine Chemistry.

Synthesis, effect of substituents on the regiochemistry and equilibrium studies of tetrazolo[1,5-a]pyrimidine/2-azidopyrimidines

Paulo R. S. Salbego, N. Zanatta, C. Frizzo, 2017, Beilstein journal of organic chemistry.

Synthesis of novel quinolines using TsOH/ionic liquid under microwave

Mara R. B. Marzari, N. Zanatta, C. Frizzo, 2012 .

Pyrazole synthesis under microwave irradiation and solvent-free conditions

Mara R. B. Marzari, N. Zanatta, C. Frizzo, 2010 .

Succinic acid dihydrazide: a convenient N,N-double block for the synthesis of symmetrical and non-symmetrical succinyl-bis[5-trifluoro(chloro)methyl-1H-pyrazoles]

N. Zanatta, M. Martins, H. Bonacorso, 2010 .

Synthesis of Novel 3-Amino-5-trifluoromethylazoles: A Convenient Method of Obtaining N-(Azol-3-yl)amines

N. Zanatta, M. Martins, H. Bonacorso, 2006 .

Synthesis and antimicrobial activity of new (4,4,4-trihalo-3-oxo-but-1-enyl)-carbamic acid ethyl esters, (4,4,4-trihalo-3-hydroxy-butyl)-carbamic acid ethyl esters, and 2-oxo-6-trihalomethyl-[1,3]oxazinane-3-carboxylic acid ethyl esters.

N. Zanatta, S. H. Alves, M. Martins, 2006, Bioorganic & medicinal chemistry.

Straightforward and Regiospecific Synthesis of Pyrazole-5-carboxylates from Unsymmetrical Enaminodiketones

N. Zanatta, M. Martins, H. Bonacorso, 2008 .

Haloacetylated enol ethers. 11. Synthesis of 1‐methyl‐ and 1‐phenyl pyrazole‐3(5)‐ethyl esters. A one‐pot procedure

N. Zanatta, M. Martins, H. Bonacorso, 1999 .

Pyrazole‐Enaminones as Promising Prototypes for the Development of Analgesic Drugs

N. Zanatta, P. Nogara, J. D. da Rocha, 2020 .

Regioselective Synthesis of 5-(Trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidines from β-Enamino Diketones

N. Zanatta, C. Frizzo, M. Martins, 2019, Synthesis.

Regioselective synthesis and characterization of new 3‐aryl‐7‐trifluoromethyl‐[1,2,4]triazolo[4,3–a]pyrimidines

N. Zanatta, M. Martins, H. Bonacorso, 2011 .

Divergent and Regioselective Synthesis of (Trifluoromethyl/carboxyethyl)benzo[4,5]imidazo[1,2‐ a ]pyrimidines from β‐Enamino Diketones

N. Zanatta, M. Martins, H. Bonacorso, 2020 .

Crystal Structure, Aromatic Character and AM1 Calculations of 2-(N’-Benzylidenehydrazino)-4-trifluoromethyl-pyrimidine and 2-(N’-2-Methylbenzylidenehydrazino)-5-methyl-4-trifluoromethyl-pyrimidine

N. Zanatta, M. Martins, H. Bonacorso, 2010 .

New succinyl-spaced pyrazoles: Regioselective synthesis of 1,4-bis[5-(trichloromethyl)-1H-pyrazol-1-yl]butane-1,4-diones

N. Zanatta, M. Martins, H. Bonacorso, 2011 .

Regiospecific synthesis of trichloromethyl substituted 4,5-dihydro-1H-1 -tosylpyrazoles

N. Zanatta, R. Lourega, M. Martins, 2007 .

Synthesis in Water and Antimicrobial Activity of 5-Trichloromethyl-4,5-dihydroisoxazoles

Mariano A. Pereira, M. Martins, A. Flores, 2013 .

Synthesis of new trihalomethylated and non-symmetrical substituted 2-(1H-pyrazolyl)-5-(1H-pyrazolylcarbonyl)pyridines

N. Zanatta, M. Martins, H. Bonacorso, 2009 .

Non-Condensed Trifluoromethylated 5,5-Bicycles: Synthesis of 2-(3-Alkyl(phenyl)-1H-pyrazol-1-yl)-4-phenyl-5-alkylthiazole and -4,5,6,7-tetrahydrobenzothiazole Systems

N. Zanatta, M. Martins, H. Bonacorso, 2002 .

New 1-(Spiro[chroman-2,1′-cycloalkan]-4-yl)-1H-1,2,3-Triazoles: Synthesis, QTAIM/MEP analyses, and DNA/HSA-binding assays

Paulo R. S. Salbego, N. Zanatta, B. Iglesias, 2020 .

DAST promotes the synthesis of new 5-(trifluoromethyl)-3-(1,1-difluoroethan-2-yl)-1H-pyrazoles

N. Zanatta, M. Martins, H. Bonacorso, 2009 .

Eco-friendly synthesis and antioxidant activity of new trifluoromethyl-substituted N-(pyrimidin-2-yl)benzo[d]thiazol-2-amines and some N-derivatives

N. Zanatta, F. Soares, M. Martins, 2016, Monatshefte für Chemie - Chemical Monthly.

Regiochemical Control of Pyrazoles by Solvent and β‐Enamino Diketone Structure: Regioselective Synthesis of 4,5‐Disubstituted N‐Phenylpyrazoles

Davana S. Gonçalves, D. Back, S. Moura, 2017 .

A Convenient Method to Obtain 4,5-Dihydro-1H-Methylpyrazoles by A Ring Transformation Reaction

N. Zanatta, M. Martins, H. Bonacorso, 2000 .

Novel 7-(1H-pyrrol-1-yl)spiro[chromeno[4,3-b]quinoline-6,1′-cycloalkanes]: synthesis, cross-coupling reactions, and photophysical properties

N. Zanatta, B. Iglesias, C. Frizzo, 2021 .

Synthesis of new fluorine-containing dihydrobenzo[c]acridines from trifluoroacetyl dihydronaphthalene and substituted anilines

N. Zanatta, M. B. Costa, M. Martins, 2005 .

Synthesis of 1H‐1,2,3‐Triazoles—Rufinamide Analogues by 1,3‐Dipolar Cycloaddition and Electrocyclization Reactions of Trifluoroacetyl Enolethers under Thermal Solventless Conditions.

N. Zanatta, M. Martins, H. Bonacorso, 2014 .

Solvent effects on the 17O NMR chemical shifts of 4-dimethylsulfoximide-1,1,1-trifluoro-3-alken-2-ones

N. Zanatta, M. Martins, A. Sinhorin, 2003 .

13C NMR Chemical Shifts Substituent Effects of (E)- and (Z)-N-ethyl-N-Methylamides

N. Zanatta, M. Martins, H. Bonacorso, 1992 .

NMR chemical shift substituent effects: 2‐α‐monosubstituted N,N‐diethylacetamides

M. Martins, R. Rittner, 1980 .

Preparation of trichloroacetoamidoxime in aqueous media and application in one pot synthesis of 1,2,4-oxadiazoles

M. Martins, Dalila Venzke, P. T. Campos, 2009 .

Preparation and crystal structure determination of adducts of copper(II) chloride with 3-aryl-1-(imino-pyridin-2-yl-methyl)-5-hydroxy-5-trifluoromethyl-4,5-dihydro-1H-pyrazoles

N. Zanatta, M. Martins, H. Bonacorso, 2003 .

Regiospecific synthesis of 3H‐pyrido[2,3‐b][1,4]diazepin‐4(5H)‐ones via haloform reaction with the isolation of N3‐[3‐oxo‐4,4,4‐trichloroalk‐1‐en‐1‐yl]‐2,3‐diaminopyridine intermediates

N. Zanatta, R. Lourega, M. Martins, 2009 .

Antimalarial activity of 4-(5-trifluoromethyl-1H-pyrazol-1-yl)-chloroquine analogues.

N. Zanatta, R. Soares, M. D. de Souza, 2006, Bioorganic & medicinal chemistry letters.

Haloacetylated enol ethers: 18

N. Zanatta, Daniel J. Emmerich, M. Martins, 2003 .

Haloacetylated enol ethers. 6 [5]. Synthesis of 4,5-trimethylene-4,5-dihydroisoxazoles

N. Zanatta, M. Martins, A. Flores, 1996 .

13C NMR chemical shifts of heterocycles. Empirical substituent effects in 5‐halomethyl‐5‐hydroxy‐4,5‐dihydroisoxazoles

M. Martins, Anna C. L. Martins, 1994 .

Activity of 4,5-dihydro-1H-pyrazoles against Mycobacterium tuberculosis and nontuberculous mycobacteria.

N. Zanatta, D. Ramos, C. Frizzo, 2014, International journal of antimicrobial agents.

Formation of a penta- or hexacoordinated Cu−(II) semicarbazone complex: Revisiting semicarbazone metal complexes

Paulo R. S. Salbego, N. Zanatta, E. R. Garbelini, 2021 .

A Convenient Preparation of 4-Methyl- and 4-Phenylseleno-1,1,1-trihalo-3-alken-2-ones and their Usefulness in the Synthesis of 3-Trihalomethylisoselenazoles

N. Zanatta, M. Martins, A. Sinhorin, 2002 .

Brominated Trihalomethylenones as Versatile Precursors to 3‐Ethoxy, ‐Formyl, ‐Azidomethyl, ‐Triazolyl, and 3‐Aminomethyl Pyrazoles

N. Zanatta, C. Frizzo, M. Martins, 2013 .

Synthesis of new halo-containing acetylenes and their application to the synthesis of azoles

N. Zanatta, Daniel J. Emmerich, M. Martins, 2004 .

Straightforward Method for Regioselective Reduction of 3-Acyl-Substituted 2-(Trifluoromethyl)-2H-chromen-5-one and Chromane Scaffolds in NaBH4/Ethanol Medium.

N. Zanatta, M. Martins, H. Bonacorso, 2013 .

A Convenient One-Pot Synthesis of 5-Carboxyisoxazoles: Trichloromethyl Group as a Carbonyl Group Precursor.

N. Zanatta, M. Martins, A. Sinhorin, 2000 .

HALOACETYLATED ENOL ETHERS: 16[5] REGIOSPECIFIC SYNTHESIS OF 5-TRICHLOROMETHYL-PYRAZOLES

N. Zanatta, M. Martins, A. Flores, 2002 .

Synthesis of novel trifluoromethylated β-acetal-diols and their application to the synthesis of 3-ethoxy-5-hydroxy-5-trifluoromethyl-pyrrolidin-2-one

N. Zanatta, M. Martins, H. Bonacorso, 2001 .

Haloacetylated enol ethers: 3. Synthesis of 3,3a,4,5,6,7‐hexahydro‐3‐halomethylbenzoisoxazoles

N. Zanatta, M. Martins, A. Flores, 1995 .

Efficient synthesis and dehydration reaction of trichloromethylated 2-(3-phenyl-5-hydroxy-4,5-dihydro-1H-pyrazol-1-yl)-4-aryl-5-alkylthiazoles

N. Zanatta, M. Martins, H. Bonacorso, 2003 .

MOLECULAR STRUCTURE OF HETEROCYCLES. V. SOLVENT EFFECTS ON THE 17O NMR CHEMICAL SHIFTS OF 5-TRICHLOROMETHYL-5-HYDROXY-4, 5-DIHYDROISOXAZOLES†

N. Zanatta, M. Martins, A. Sinhorin, 2001 .

A CONVENIENT SYNTHESIS OF 4-TRICHLOROMETHYL-PYRIMIDIN-2-YLAMINE DERIVATIVES

N. Zanatta, M. Martins, H. Bonacorso, 2001 .

Haloacetylated enol ethers. 13†. Synthesis of N-[1-aryl(alkyl)-3-oxo-4,4,4-trichloro-1-buten-1-yl]-o-phenylenediamines and 2-trichloromethyl-4-aryl-3H-1,5-benzodiazepines

N. Zanatta, M. Martins, H. Bonacorso, 1999 .

Efficient Synthesis of New 1-(Alkyl(aryl))-5-(3,3,3-trihalo-2-oxopropylidene)pyrrolidin-2-ones

M. Martins, H. Bonacorso, Lucas Pizzuti, 2008 .

Regiospecific Allylic Mono- and Dibromination of 4-Methoxy-1,1,1-trihalo-3-alken-2-ones and 5-Methoxy-1,1,1,2,2-pentafluoro-4-hexen-2-one, and Their Applications to the Synthesis of Heterocycles.

M. Martins, 2002 .

Aluminum promotes easy access to high substituted trihalomethyl triazolyl homoallylic alcohols

N. Zanatta, M. Martins, H. Bonacorso, 2013 .

Dampened circumrotation by CH···π interactions in hydrogen bonded [2]rotaxanes.

J. Berná, M. Martins, Raúl-Ángel Orenes, 2012, Chemical communications.

Nanostructure Evaluation of Ionic Liquid Aggregates by Spectroscopy

N. Zanatta, M. Villetti, C. Frizzo, 2013, Nanoscale Spectroscopy with Applications.

Aromaticity in heterocycles: new HOMA index parametrization

C. Frizzo, M. Martins, 2012, Structural Chemistry.

Photophysical, photostability, and ROS generation properties of new trifluoromethylated quinoline-phenol Schiff bases

N. Zanatta, B. Iglesias, C. Frizzo, 2021, Beilstein journal of organic chemistry.

Heteroassembly Ability of Dicationic Ionic Liquids and Neutral Active Pharmaceutical Ingredients

Paulo R. S. Salbego, M. Villetti, Carla A. A. Farias, 2018, ACS omega.

Brønsted acid–base pairs of drugs as dual ionic liquids: NMR ionicity studies

J. Elguero, C. Frizzo, M. Martins, 2015 .

Synthesis of Ethyl Pyrimidine‐4‐carboxylates from Unsymmetrical Enamino Diketones and Their Application in the First Synthesis of Pyrimido[4,5‐d]pyridazin‐8(7H)‐ones

N. Zanatta, M. Martins, H. Bonacorso, 2009 .

Synthesis of Ethyl Pyrimidine-4-carboxylatesfrom Unsymmetrical Enamino Diketones and Their Applicationin the First Synthesis of Pyrimido[4,5-d]pyridazin-8(7H)-ones

N. Zanatta, M. Martins, H. Bonacorso, 2008 .

New efficient approach for the synthesis of 2-alkyl(aryl) substituted 4H-pyrido[1,2-a]pyrimidin-4-ones

N. Zanatta, M. B. Costa, M. Martins, 2006 .

N -Alkylation of 4-Trichloromethylpyrimidinones: Synthesis of Some New and Interesting Modified Nucleoside Analogues

N. Zanatta, M. Martins, H. Bonacorso, 2009 .

Regiospecific synthesis of polyfluorinated heterocycles

N. Zanatta, S. Moura, M. Martins, 2003 .

15N NMR spectroscopy of 3‐substituted 5‐trichloromethyl‐1,2‐dimethyl‐1H‐pyrazolium chlorides

N. Zanatta, M. Martins, A. Sinhorin, 2002 .

Bicyclic thiaspiro[4.n]alkanones: investigating their total stereochemistry achieved by the catalyst-free sulfa-Michael reaction

N. Zanatta, C. Frizzo, M. Martins, 2022, Journal of Molecular Structure.

Efficient Synthesis of (1,2,3‐Triazol‐1‐yl)methylpyrimidines from 5‐Bromo‐1,1,1‐trifluoro‐4‐methoxypent‐3‐en‐2‐one

N. Zanatta, M. Martins, H. Bonacorso, 2017 .

Regiochemistry of cyclocondensation reactions in the synthesis of polyazaheterocycles

N. Zanatta, D. Back, C. Frizzo, 2017, Beilstein journal of organic chemistry.

New Efficient Approach for the Synthesis of 2-Alkyl(aryl) Substituted 4H-Pyrido[1,2-a]pyrimidin-4-ones.

N. Zanatta, M. B. Costa, M. Martins, 2006 .

ChemInform Abstract: Regiospecific Synthesis of 3-Alkyl-2-aryl-4-trifluoromethylbenzo[h]quinolines by Intramolecular Cyclization of N-(2-Alkyl-1-aryl-3-oxo-4,4,4-trifluorobut-1-en-1-yl)-1-naphthylamines.

N. Zanatta, M. Martins, H. Bonacorso, 2002 .

SYNTHESIS OF SOME N-[1-ALKYL(ARYL)- 3-OXO-4,4,4-TRICHLORO(TRIFLUORO)- 1-BUTEN-1-YL]-o-AMINOPHENOLS AND o-PHENYLENEDIAMINES AS POTENTIAL ANTICANCER AGENTS

N. Zanatta, M. Martins, H. Bonacorso, 2002 .

Haloacetylated enol ethers: 15. Study of the regiochemistry of the cyclo-condensation of β-alkoxyvinyl trihalomethyl ketones with N-methyl thiourea†

N. Zanatta, M. Martins, H. Bonacorso, 2000 .

A Convenient Synthetic Method for Fully Conjugated 3-Alkyl- and 3-Aryl-5-trifluoromethyl-1-methyl-1,2-thiazine 1-Oxide from β-Alkoxyvinyl Trifluoromethyl Ketones

N. Zanatta, R. Lourega, M. Martins, 2000 .

Useful approach for O-functionalization of trifluoromethyl-substituted spirotetracyclic isoxazolines, and their application in the synthesis of 1,2,3-triazole derivatives

N. Zanatta, C. Frizzo, M. Martins, 2018, Journal of Fluorine Chemistry.

Antidepressant-like effect of the novel MAO inhibitor 2-(3,4-dimethoxy-phenyl)-4,5-dihydro-1H-imidazole (2-DMPI) in mice

C. Cunha, P. Dombrowski, N. Zanatta, 2012, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Enol ethers and acetals: acylation with dichloroacetyl, acetyl and benzoyl chloride in ionic liquid medium

Mara R. B. Marzari, N. Zanatta, E. Guarda, 2012 .

Synthesis of Penta-2,4-dienenitriles by the Horner–Wadsworth–Emmons Olefination of Enones

N. Zanatta, M. Martins, H. Bonacorso, 2017, Synthesis.

Regiospecific synthesis of new fatty N-acyl trihalomethylated pyrazoline derivatives from fatty acid methyl esters (FAMEs)

M. G. D’Oca, M. Martins, A. Flores, 2012 .

13C NMR Chemical Shifts of Heterocycles: Empirical Substituent Effects in 5-Halomethylisoxazoles

N. Zanatta, M. Martins, R. Freitag, 1994 .

Supramolecular Similarity in Polymorphs: Use of Similarity Indices (IX)

N. Zanatta, M. Martins, T. Orlando, 2019, ACS omega.

Effects per se of Organic Solvents in the Cerebral Acetylcholinesterase of Rats

N. Zanatta, V. Morsch, M. Schetinger, 2005, Neurochemical Research.

6-Hydrazinonicotinic acid hydrazide: an useful precursor for chemo- and regioselective synthesis of new heteroaryl-linked pyridinohydrazones

N. Zanatta, M. Martins, H. Bonacorso, 2012 .

Haloacetylated enol ethers: 12 [18]. Regiospecific synthesis and structural determination of stable 5-hydroxy-1H-pyrazolines

N. Zanatta, M. Martins, H. Bonacorso, 1999 .

Haloacetylated Enol Ethers. Part 12. Regiospecific Synthesis and Structural Determination of Stable 5-Hydroxy-1H-pyrazolines.

N. Zanatta, M. Martins, H. Bonacorso, 2010 .

MOLECULAR STRUCTURE OF HETEROCYCLES: 17O NMR CHEMICAL SHIFTS: TORSION ANGLE RELATIONSHIPS IN 3-ALKYL SUBSTITUTED 4,5-DIHYDROISOXAZOLES AND ISOXAZOLES†

N. Zanatta, M. Martins, A. Sinhorin, 2001 .

Haloacetylated enol ethers. 14 [6]. Reaction of β-alkoxyvinyl trifluoromethyl ketones with N-methylhydroxylamine

N. Zanatta, M. Martins, H. Bonacorso, 1999 .

A Convenient Method for the Synthesis of 2‐Trichloromethyl‐4‐p‐ substituted‐phenyl‐3H‐1,5‐benzodiazepines.

N. Zanatta, M. Martins, H. Bonacorso, 1997 .

Novel aryl(heteroaryl)-substituted (pyrimidyl)benzamide-based BF2 complexes: Synthesis, photophysical properties, BSA-binding, and molecular docking analysis

N. Zanatta, B. Iglesias, P. Nogara, 2019, Dyes and Pigments.

Synthesis, 17O NMR spectroscopy and structure of 2-trifluoroacetyl-1-methoxycycloalkenes

N. Zanatta, M. B. Costa, S. Moura, 2005 .

Haloacetylated Compounds: Solvent Effects on the 17O Nmr Chemical Shifts of 1,1,1-Trichloro-4-Methoxy-3-Alken-2-Ones

N. Zanatta, M. Martins, H. Bonacorso, 1999 .

Efficient synthetic access to novel N-(Pyrimidinyl)-N-(1H-benzo[d]imidazolyl)amines in an aqueous medium

N. Zanatta, M. Martins, H. Bonacorso, 2015, Monatshefte für Chemie - Chemical Monthly.

NMR chemical shift substituent effects. 3—α‐Monosubstituted N,N‐diethylacetamides; bifunctional compounds in LSR experiments

M. Martins, R. Rittner, Maria Alejandra Gutierrez, 1982 .

Conformational Studies of α-Substituted Carbonyl Compounds by I. R. Spectroscopy. II. α-Heterosubstituted N, N-Diethylacetamides

M. Martins, R. Rittner, P. Olivato, 1981 .

Ultrasound Promoted Synthesis of 2‐Imidazolines in Water: A Greener Approach Toward Monoamine Oxidase Inhibitors.

N. Zanatta, M. Martins, J. Ferreira, 2009 .

Ionic liquid and Lewis acid combination in the synthesis of novel (E)-1-(benzylideneamino)-3-cyano-6-(trifluoromethyl)-1H-2-pyridones

Mara R. B. Marzari, N. Zanatta, C. Frizzo, 2011 .

Hybridized 4‐Trifluoromethyl‐(1,2,3‐triazol‐1‐yl)quinoline System: Synthesis, Photophysics, Selective DNA/HSA Bio‐interactions and Molecular Docking

N. Zanatta, B. Iglesias, P. Nogara, 2021, ChemBioChem.

Synthesis, Crystal Structure, and Supramolecular Understanding of 1,3,5-Tris(1-phenyl-1H-pyrazol-5-yl)benzenes

N. Zanatta, M. Hörner, C. Frizzo, 2017, Molecules.

Ionic Liquid and Lewis Acid Combination in the Synthesis of Novel (E)-1-(Benzylideneamino)-3-cyano-6-(trifluoromethyl)-1H-2-pyridones.

Mara R. B. Marzari, N. Zanatta, C. Frizzo, 2012 .

Synthesis, 11B- and 19F NMR spectroscopy, and optical and electrochemical properties of novel 9-aryl-3-(aryl/heteroaryl)-1,1-difluoro-7-(trifluoromethyl)-1H-[1,3,5,2]oxadiazaborinino[3,4-a][1,8]naphthyridin-11-ium-1-uide complexes

N. Zanatta, B. Iglesias, J. Rocha, 2016 .

Fluorinated N-Quinoxaline-Based Boron Complexes: Synthesis, Photophysical Properties, and Selective DNA/BSA BioInteraction

N. Zanatta, B. Iglesias, P. Nogara, 2022, Journal of Molecular Structure.

1,1-Difluoro-3-aryl(heteroaryl)-1H-pyrido[1,2-c][1,3,5,2]oxadiazaborinin-9-ium-1-uides: synthesis; structure; and photophysical, electrochemical, and BSA-binding studies

N. Zanatta, B. Iglesias, P. Nogara, 2018 .

Multinuclear NMR spectroscopy, photophysical, electrochemical and DNA-binding properties of fluorinated 1,8-naphthyridine-based boron heterocycles

N. Zanatta, B. Iglesias, M. Martins, 2018 .

General method for dehydration, intramolecular cyclization, and fluorination of trifluoromethyl-1H-pyrazoles using DAST

N. Zanatta, M. Martins, H. Bonacorso, 2010 .

A telescoped protocol for the synthesis of new pyrrolo [3,4-d]pyridazinones by cascade reactions

N. Zanatta, M. Martins, H. Bonacorso, 2015 .

Synthesis of a Novel 1,4-Dicarbonyl Scaffold – Ethyl 3-Formyl-4,5-dihydrofuran-2-carboxylate – and Its Application to the Synthesis of Pyridazines

N. Zanatta, M. Martins, H. Bonacorso, 2020, Synthesis.

A Telescoped Protocol for the Synthesis of New Pyrrolo[3,4‐d]pyridazinones by Cascade Reactions.

N. Zanatta, M. Martins, H. Bonacorso, 2016 .

Understanding the crystalline formation of triazene N-oxides and the role of halogen⋯π interactions

M. Hörner, C. Frizzo, M. Martins, 2018 .

Regioselective Synthesis of Pyrazolyl-pyrimidine Hybrids of Pharmacological Interest

N. Zanatta, P. Nogara, J. Rocha, 2020, Synthesis.

4-(Trifluoromethyl) coumarin-fused pyridines: Regioselective synthesis and photophysics, electrochemical, and antioxidative activity

N. Zanatta, B. Iglesias, M. Martins, 2021 .

7-Amine-spiro[chromeno[4,3-b]quinoline-6,1'-cycloalkanes]: Synthesis and cholinesterase inhibitory activity of structurally modified tacrines.

N. Zanatta, P. Nogara, J. Rocha, 2021, Bioorganic chemistry.

Ionic Liquids in Heterocyclic Synthesis

N. Zanatta, C. Frizzo, M. Martins, 2008 .

Thermal and Oxidative Syntheses, Structure, and Optical Properties of 2,6,8-Trisubstituted 1,2,3-Triazolo[4′,5′:3,4]pyrazolo[1,5-a]pyrimidin-2-ium-1(3)-ides

N. Zanatta, B. Iglesias, M. Martins, 2023, Journal of Molecular Structure.

Convergent synthesis and cytotoxicity of novel trifluoromethyl-substituted (1 H -pyrazol-1-yl)(quinolin-4-yl) methanones

N. Zanatta, P. Nogara, J. Rocha, 2016 .

Trifluoromethyl β‐Enamino Diketones as Dual Substrates for the Synthesis of 5‐Benzoyl‐6‐(trifluoromethyl)pyrimidines and their Pyrimidin‐4(3 H )‐one Analogues

N. Zanatta, M. Martins, H. Bonacorso, 2020 .

Pharmaceutical Salts: Solids to Liquids by Using Ionic Liquid Design

C. Frizzo, A. Tier, M. Martins, 2013 .

Design, Synthesis, and Cholinesterase Inhibitory Activity of 4‐Substituted‐6‐(trihalomethyl)‐2‐methylsulfanyl Pyrimidines

N. Zanatta, P. Nogara, J. Rocha, 2021, ChemistrySelect.

1,2,3-Triazolo[4,5-b]aminoquinolines: Design, synthesis, structure, acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activity, and molecular docking of novel modified tacrines.

N. Zanatta, P. Nogara, M. Martins, 2023, Bioorganic chemistry.

Simplified Approach to the Regiospecific Synthesis of Trichloromethylpyrazolines Using Microwave Irradiation.

N. Zanatta, Paulo I. R. Muraro, C. Frizzo, 2009 .

Microwave‐Assisted Synthesis of 5‐Trichloromethyl Substituted 1‐Phenyl‐1H‐pyrazoles and 1,2‐Dimethylpyrazolium Chlorides.

N. Zanatta, S. Moura, M. Martins, 2003 .

Microwave-Assisted Synthesis of 5-Hydroxy-5-trichloromethyl-4,5-dihydroisoxazoles.

N. Zanatta, M. Martins, A. Sinhorin, 2002 .

Regiospecific Acylation of Acetals. A Convenient Method to Obtain β-Methoxyvinyl Trichloromethyl Ketones.

N. Zanatta, M. Martins, H. Bonacorso, 1999 .

Heterocyclic Compounds from Trihaloacetylated Enol Ethers and Nitrogen Nucleophiles. Part 2. Trihaloacetylated Enol Ethers. General Synthetic Procedure and Heterocyclic Ring Closure Reactions with Hydroxylamine.

P. Fischer, M. Martins, Günter Clar, 1991 .

4-Alkoxy-1,1,1-Trihalo-3-Alken-2-ones as Building Blocks for Trihalomethylated Heterocycles. Synthesis of 4-Trihalomethyl-2-Pyrimidinones

N. Zanatta, M. Martins, I. Blanco, 1991 .