Jian Ding

发表

Novel Sphingosine Kinase 1 Inhibitor Suppresses Growth of Solid Tumor and Inhibits the Lung Metastasis of Triple-Negative Breast Cancer.

F. Gao, Lin-jiang Tong, Hong Liu, 2022, Journal of medicinal chemistry.

Optimization of Brigatinib as New Wild-Type Sparing Inhibitors of EGFRT790M/C797S Mutants.

Tao Zhang, Lin-jiang Tong, C. Yun, 2022, ACS medicinal chemistry letters.

Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-Generation Epidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations.

Tao Zhang, Lin-jiang Tong, Xiaoyun Lu, 2022, Journal of medicinal chemistry.

Discovery of Potent and Noncovalent Reversible EGFR Kinase Inhibitors of EGFR

Tao Zhang, Xia Wang, Honglin Li, 2019 .

Isoquinoline-1,3,4-trione Derivatives Inactivate Caspase-3 by Generation of Reactive Oxygen Species*

F. Nan, Jun-qing Du, Jian Ding, 2008, Journal of Biological Chemistry.

The short-time treatment with curcumin sufficiently decreases cell viability, induces apoptosis and copper enhances these effects in multidrug-resistant K562/A02 cells

Jin-jian Lu, Jian Ding, Jian Ding, 2011, Molecular and Cellular Biochemistry.

Functional Role of Histidine in the Conserved His-x-Asp Motif in the Catalytic Core of Protein Kinases

Lun Zhang, Yi Zang, Jia Li, 2015, Scientific Reports.

Structure-Aided Design, Synthesis, and Biological Evaluation of Potent and Selective Non-Nucleoside Inhibitors Targeting Protein Arginine Methyltransferase 5.

Hong Yang, Jian Ding, Yi Zhang, 2022, Journal of medicinal chemistry.

Synthesis and in vitro and in vivo biological evaluation of tissue-specific bisthiazole Histone deacetylase (HDAC) inhibitors.

Yi Chen, F. Nan, Jia Li, 2019, Journal of medicinal chemistry.

A Novel Immunostimulator, N2-[α-O-Benzyl-N-(acetylmuramyl)-l-alanyl-d- isoglutaminyl]-N6-trans-(m-nitrocinnamoyl)-l-lysine, and Its Adjuvancy on the Hepatitis B Surface Antigen

Jian Ding, Hong-zhen Yang, Bai-he Liu, 2005 .

Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities.

Yi Chen, Z. Miao, Pingyuan Wang, 2023, European journal of medicinal chemistry.

Design, synthesis and biological evaluation of KRASG12C-PROTACs.

Huibin Zhang, Jinpei Zhou, Tong Zhao, 2023, Bioorganic & medicinal chemistry.

Design, synthesis and pharmacological evaluation of 2,3-dihydrobenzofuran IRAK4 inhibitors for the treatment of diffuse large B-cell lymphoma.

Huibin Zhang, Jinpei Zhou, W. Duan, 2023, European journal of medicinal chemistry.

Discovery of pyrrolo[2,3-d]pyrimidin-4-one derivative YCH3124 as a potent USP7 inhibitor for cancer therapy.

Jian Ding, Chun-hao Yang, Jin-Xue He, 2024, European journal of medicinal chemistry.

The HDAC inhibitor GCJ-490A suppresses c-Met expression through IKKα and overcomes gefitinib resistance in non-small cell lung cancer

Yi Chen, Fajun Nan, Jian Ding, 2022, Cancer biology & medicine.