I. Legen

发表

Physiologically based absorption modeling to predict bioequivalence of controlled release and immediate release oral products

A. Mitra, R. Velagapudi, Boštjan Petek, 2019, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Determining The Pressure-Generating Capacity of The Classical and Alternative In Vitro Dissolution Methods Using a Wireless Motility Capsule

I. Legen, I. Grabnar, Melita Hribar, 2018, Journal of Pharmaceutical Innovation.

A Novel Intestine Model Apparatus for Drug Dissolution Capable of Simulating the Peristaltic Action

I. Legen, Melita Hribar, J. Trontelj, 2016, AAPS PharmSciTech.

d-Glucose Triggers Multidrug Resistance–Associated Protein (MRP)-Mediated Secretion of Fluorescein Across Rat Jejunum in Vitro

I. Legen, A. Kristl, 2004, Pharmaceutical Research.

Factors affecting the microclimate pH of the rat jejunum in ringer bicarbonate buffer.

I. Legen, A. Kristl, 2003, Biological & pharmaceutical bulletin.

Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Levetiracetam.

J. Polli, V. Shah, J. Dressman, 2015, Journal of pharmaceutical sciences.

The influence of buffer composition on tissue integrity during permeability experiments "in vitro".

M. Veber, I. Legen, A. Kristl, 2004, International journal of pharmaceutics.

In vitro–In vivo Relationship and Bioequivalence Prediction for Modified-Release Capsules Based on a PBPK Absorption Model

Boštjan Petek, I. Legen, Rebeka Jereb, 2019, AAPS PharmSciTech.

Comparison of different intestinal epithelia as models for absorption enhancement studies.

I. Legen, J. Kerč, M. Salobir, 2005, International journal of pharmaceutics.

The evaluation of some pharmaceutically acceptable excipients as permeation enhancers for amoxicillin.

I. Legen, J. Kerč, M. Salobir, 2006, International journal of pharmaceutics.

pH and energy dependent transport of ketoprofen across rat jejunum in vitro.

I. Legen, A. Kristl, 2003, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Ketoprofen‐induced intestinal permeability changes studied in side‐by‐side diffusion cells

I. Legen, A. Kristl, 2002, The Journal of pharmacy and pharmacology.

Neuro-fuzzy Models as an IVIVR Tool and Their Applicability in Generic Drug Development

I. Legen, Jerneja Opara, 2014, The AAPS Journal.

Design of an Innovative Advanced Gastric Simulator

J. Diaci, I. Legen, Lovro Kuščer, 2019, Dissolution Technologies.

A Novel Beads-Based Dissolution Method for the In Vitro Evaluation of Extended Release HPMC Matrix Tablets and the Correlation with the In Vivo Data

S. Baumgartner, I. Legen, B. Markun, 2012, The AAPS Journal.

Determining the Polymer Threshold Amount for Achieving Robust Drug Release from HPMC and HPC Matrix Tablets Containing a High-Dose BCS Class I Model Drug: In Vitro and In Vivo Studies

S. Baumgartner, I. Legen, B. Markun, 2015, AAPS PharmSciTech.

Biopharmaceutical classification of desloratadine – not all drugs are classified the easy way

I. Legen, J. Trontelj, Nadica Sibinovska, 2020, Acta pharmaceutica.

Suitability of isolated rat jejunum model for demonstration of complete absorption in humans for BCS-based biowaiver request.

K. Kristan, T. Rižner, I. Legen, 2012, Journal of pharmaceutical sciences.

Predictive Potential of BCS and Pharmacokinetic Parameters on Study Outcome: Analysis of 198 In Vivo Bioequivalence Studies

I. Legen, I. Grabnar, Rebeka Jereb, 2023, European Journal of Drug Metabolism and Pharmacokinetics.

Permeability of a novel β‐lactamase inhibitor LK‐157 and its ester prodrugs across rat jejunum in vitro

I. Legen, A. Preželj, Lovro Selič, 2009 .

Mechanistic study of model drug release from HPMC matrices in fed gastric media

I. Legen, J. Trontelj, Helena Vrbanac, 2020 .

Simulated migrating motor complex and its impact on the release properties of hydrophilic matrix systems

I. Legen, J. Trontelj, Helena Vrbanac, 2020 .

Determining The Pressure-Generating Capacity of The Classical and Alternative In Vitro Dissolution Methods Using a Wireless Motility Capsule

I. Legen, I. Grabnar, Melita Hribar, 2018, Journal of Pharmaceutical Innovation.

Predictive Potential of Acido-Basic Properties, Solubility and Food on Bioequivalence Study Outcome: Analysis of 128 Studies

I. Legen, I. Grabnar, Rebeka Jereb, 2023, Drugs in R&D.

Polarised transport of monocarboxylic acid type drugs across rat jejunum in vitro: the effect of mucolysis and ATP-depletion.

I. Legen, A. Kristl, S. Žakelj, 2003, International journal of pharmaceutics.

The biorelevant simulation of gastric emptying and its impact on model drug dissolution and absorption kinetics.

Boštjan Petek, I. Legen, J. Trontelj, 2020, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

A Novel Beads-Based Dissolution Method for the In Vitro Evaluation of Extended Release HPMC Matrix Tablets and the Correlation with the In Vivo Data

S. Baumgartner, I. Legen, B. Markun, 2012, The AAPS Journal.