Zhoumeng Lin

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Mathematical modeling and simulation in animal health - Part II: principles, methods, applications, and value of physiologically based pharmacokinetic modeling in veterinary medicine and food safety assessment.

R. Gehring, T. Lavé, J. Mochel, 2016, Journal of veterinary pharmacology and therapeutics.

Physiologically based pharmacokinetic model calibration, evaluation, and performance assessment

W. Chou, Yi-Hsien Cheng, Zhoumeng Lin, 2020 .

Bacterial endotoxin (lipopolysaccharide) binds to the surface of gold nanoparticles, interferes with biocorona formation and induces human monocyte inflammatory activation

Zhenzhen Shi, Yang Li, Albert Duschl, 2017, Nanotoxicology.

Tissue residue depletion kinetics and withdrawal time estimation of doxycycline in grass carp, Ctenopharyngodon idella, following multiple oral administrations.

N. Xu, X. Ai, Zhoumeng Lin, 2019, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Probabilistic human health risk assessment of perfluorooctane sulfonate (PFOS) by integrating in vitro, in vivo toxicity, and human epidemiological studies using a Bayesian-based dose-response assessment coupled with physiologically based pharmacokinetic (PBPK) modeling approach.

W. Chou, Zhoumeng Lin, 2020, Environment international.

A physiologically based pharmacokinetic model of doxycycline for predicting tissue residues and withdrawal intervals in grass carp (Ctenopharyngodon idella).

N. Xu, W. Chou, Zhoumeng Lin, 2020, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Effect of temperature on plasma and tissue kinetics of doxycycline in grass carp (Ctenopharyngodon idella) after oral administration

Jing Dong, Yongtao Liu, Shun Zhou, 2019, Aquaculture.

Probabilistic risk assessment of gold nanoparticles after intravenous administration by integrating in vitro and in vivo toxicity with physiologically based pharmacokinetic modeling

N. Monteiro-Riviere, J. Riviere, Yi-Hsien Cheng, 2018, Nanotoxicology.

Translating Nanomedicine to Comparative Oncology—the Case for Combining Zinc Oxide Nanomaterials with Nucleic Acid Therapeutic and Protein Delivery for Treating Metastatic Cancer

Yi-Hsien Cheng, R. DeLong, Zhoumeng Lin, 2019, The Journal of Pharmacology and Experimental Therapeutics.

Short-term oral atrazine exposure alters the plasma metabolome of male C57BL/6 mice and disrupts α-linolenate, tryptophan, tyrosine and other major metabolic pathways.

Dean P. Jones, James R. Roede, N. Filipov, 2014, Toxicology.

Role of PUMA in methamphetamine-induced neuronal apoptosis.

Zhoumeng Lin, Jingtao Xu, W. Xie, 2016, Toxicology letters.

A framework for meta-analysis of veterinary drug pharmacokinetic data using mixed effect modeling.

R. Gehring, J. Riviere, Zhoumeng Lin, 2015, Journal of pharmaceutical sciences.

Methamphetamine exposure triggers apoptosis and autophagy in neuronal cells by activating the C/EBPβ‐related signaling pathway

Zhoumeng Lin, W. Xie, Qinfang Luo, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Physiological parameter values for physiologically based pharmacokinetic models in food‐producing animals. Part III: Sheep and goat

Jennifer L Davis, F. Maunsell, J. Riviere, 2020, Journal of veterinary pharmacology and therapeutics.

In vitro-in silico-based probabilistic risk assessment of combined exposure to bisphenol A and its analogues by integrating ToxCast high-throughput in vitro assays with in vitro to in vivo extrapolation (IVIVE) via physiologically based pharmacokinetic (PBPK) modeling.

Yi-Jun Lin, Zhoumeng Lin, 2020, Journal of hazardous materials.

Development of a Gestational and Lactational Physiologically Based Pharmacokinetic (PBPK) Model for Perfluorooctane Sulfonate (PFOS) in Rats and Humans and Its Implications in the Derivation of Health-Based Toxicity Values

W. Chou, Zhoumeng Lin, 2021, Environmental health perspectives.

Early sex differences in hepatic metabolic signaling in offspring of obese female mice (1033.11)

D. Harn, Zhoumeng Lin, C. Baile, 2014 .

Methamphetamine produces cardiac damage and apoptosis by decreasing melusin.

Yu Wang, Zhoumeng Lin, W. Xie, 2019, Toxicology and applied pharmacology.

Residue depletion profiles and withdrawal interval estimations of meloxicam in eggs and ovarian follicles following intravenous (Meloxicam solution for injection) and oral (Meloxidyl®) administration in domestic chickens (Gallus domesticus).

L. Tell, Zhoumeng Lin, Maaike O Clapham, 2022, Regulatory toxicology and pharmacology : RTP.

Pharmacokinetics of Mequindox and Its Marker Residue 1,4-Bisdesoxymequindox in Swine Following Multiple Oral Gavage and Intramuscular Administration: An Experimental Study Coupled with Population Physiologically Based Pharmacokinetic Modeling.

R. Gehring, J. Riviere, B. Fang, 2017, Journal of agricultural and food chemistry.

Development of a multi-route physiologically based pharmacokinetic (PBPK) model for nanomaterials: a comparison between a traditional versus a new route-specific approach using gold nanoparticles in rats

W. Kreyling, W. Chou, N. Monteiro-Riviere, 2022, Particle and fibre toxicology.

Extralabel drug use in wildlife and game animals.

Jennifer L Davis, J. Riviere, L. Tell, 2019, Journal of the American Veterinary Medical Association.

A web-based interactive physiologically based pharmacokinetic (iPBPK) model for meloxicam in broiler chickens and laying hens.

W. Chou, J. Riviere, L. Tell, 2022, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

CDK5-mediated tau accumulation triggers methamphetamine-induced neuronal apoptosis via endoplasmic reticulum-associated degradation pathway.

Zhoumeng Lin, W. Xie, Hui-jun Wang, 2018, Toxicology letters.

Honey bee medicine for veterinarians and guidance for avoiding violative chemical residues in honey.

F. Maunsell, J. Riviere, L. Tell, 2021, Journal of the American Veterinary Medical Association.

Short term feeding of industrial hemp with a high cannabidiolic acid (CBDA) content increases lying behavior and reduces biomarkers of stress and inflammation in Holstein steers

J. Coetzee, J. Griffin, G. Magnin, 2022, Scientific Reports.

Determination of Pharmacokinetic and Pharmacokinetic-Pharmacodynamic Parameters of Doxycycline against Edwardsiella ictaluri in Yellow Catfish (Pelteobagrus fulvidraco)

N. Xu, X. Ai, Zhoumeng Lin, 2021, Antibiotics.

Toxicokinetics, dose-response, and risk assessment of nanomaterials: Methodology, challenges, and future perspectives.

J. Riviere, Zhoumeng Lin, Qiran Chen, 2022, Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.

Toll-Like Receptor 4 Mediates Methamphetamine-Induced Neuroinflammation through Caspase-11 Signaling Pathway in Astrocytes

Zhoumeng Lin, W. Xie, Hui-jun Wang, 2017, Front. Mol. Neurosci..

Integration of In Vitro and In Vivo Models to Predict Cellular and Tissue Dosimetry of Nanomaterials Using Physiologically Based Pharmacokinetic Modeling

A. Gesquiere, Yi-Hsien Cheng, S. Aryal, 2022, ACS nano.

A physiologically based pharmacokinetic model for atrazine and its main metabolites in the adult male C57BL/6 mouse.

J. Fisher, M. Ross, N. Filipov, 2011, Toxicology and applied pharmacology.

Physiological parameter values for physiologically based pharmacokinetic models in food‐producing animals. Part II: Chicken and turkey

Jennifer L Davis, J. Riviere, L. Tell, 2020, Journal of veterinary pharmacology and therapeutics.

Physiological parameter values for physiologically based pharmacokinetic models in food‐producing animals. Part I: Cattle and swine

Jennifer L Davis, J. Riviere, L. Tell, 2020, Journal of veterinary pharmacology and therapeutics.

Meta-Analysis of Nanoparticle Delivery to Tumors Using a Physiologically Based Pharmacokinetic Modeling and Simulation Approach

N. Monteiro-Riviere, J. Riviere, Yi-Hsien Cheng, 2020, ACS nano.

Clinical pharmacokinetics and outcomes of oral fluconazole therapy in dogs and cats with naturally occurring fungal disease.

Jean-Sébastien Palerme, B. Kukanich, H. Joo, 2020, Journal of veterinary pharmacology and therapeutics.

Development and application of a population physiologically based pharmacokinetic model for penicillin G in swine and cattle for food safety assessment.

R. Gehring, J. Riviere, Zhoumeng Lin, 2017, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Development and Application of an interactive Physiologically Based Pharmacokinetic (iPBPK) Model to Predict Oxytetracycline Tissue Distribution and Withdrawal Intervals in Market-Age Sheep and Goats.

Mahbubul H. Riad, Jennifer L Davis, F. Maunsell, 2021, Toxicological sciences : an official journal of the Society of Toxicology.

Plasma concentrations of eleven cannabinoids in cattle following oral administration of industrial hemp (Cannabis sativa)

J. Coetzee, J. Griffin, G. Magnin, 2020, Scientific Reports.

Withdrawal Interval Estimation of Doxycycline in Yellow Catfish (Pelteobagrus fulvidraco) Using an LC-MS/MS Method Based upon QuEChERS Sampling Preparation

N. Xu, X. Ai, Zhoumeng Lin, 2021, Foods.

Development and application of a multiroute physiologically based pharmacokinetic model for oxytetracycline in dogs and humans.

R. Gehring, J. Riviere, Zhoumeng Lin, 2015, Journal of pharmaceutical sciences.

Insulin-like growth factor binding protein 5 (IGFBP5) mediates methamphetamine-induced dopaminergic neuron apoptosis.

Zhoumeng Lin, Jingtao Xu, W. Xie, 2014, Toxicology letters.

Estimation of placental and lactational transfer and tissue distribution of atrazine and its main metabolites in rodent dams, fetuses, and neonates with physiologically based pharmacokinetic modeling.

J. Fisher, M. Ross, N. Filipov, 2013, Toxicology and applied pharmacology.

Effects of DDIT4 in Methamphetamine-Induced Autophagy and Apoptosis in Dopaminergic Neurons

R. Chen, Zhoumeng Lin, W. Xie, 2016, Molecular Neurobiology.

Gestational and lactational exposure to atrazine via the drinking water causes specific behavioral deficits and selectively alters monoaminergic systems in C57BL/6 mouse dams, juvenile and adult offspring.

Shuo Xiao, N. Filipov, Zhoumeng Lin, 2014, Toxicological sciences : an official journal of the Society of Toxicology.

The construction and application of a population physiologically based pharmacokinetic model for methadone in Beagles and Greyhounds

B. Kukanich, Zhoumeng Lin, Miao Li, 2018, Journal of veterinary pharmacology and therapeutics.

Pharmacokinetics and Pharmacodynamics of Tildipirosin Against Pasteurella multocida in a Murine Lung Infection Model

R. Gehring, Z. Zeng, Zhoumeng Lin, 2018, Front. Microbiol..

Extralabel drug use in small ruminants.

Jennifer L Davis, J. Riviere, L. Tell, 2018, Journal of the American Veterinary Medical Association.

DNA damage-inducible transcript 4 (DDIT4) mediates methamphetamine-induced autophagy and apoptosis through mTOR signaling pathway in cardiomyocytes.

R. Chen, Zhoumeng Lin, W. Xie, 2016, Toxicology and applied pharmacology.

Nupr1 Modulates Methamphetamine-Induced Dopaminergic Neuronal Apoptosis and Autophagy through CHOP-Trib3-Mediated Endoplasmic Reticulum Stress Signaling Pathway

R. Chen, Zhoumeng Lin, W. Xie, 2017, Front. Mol. Neurosci..

Caspase-11 plays an essential role in methamphetamine-induced dopaminergic neuron apoptosis.

Zhoumeng Lin, W. Xie, Pingming Qiu, 2015, Toxicological sciences : an official journal of the Society of Toxicology.

Pharmacokinetics of metallic nanoparticles.

Jim E Riviere, Zhoumeng Lin, Nancy A Monteiro-Riviere, 2015, Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.

Mechanisms of toxicity and residue considerations of rodenticide exposure in food Animals-a FARAD perspective.

F. Maunsell, L. Tell, M. Jaberi-Douraki, 2022, Journal of the American Veterinary Medical Association.

Assessing Global Human Exposure to T-2 Toxin via Poultry Meat Consumption Using a Lifetime Physiologically Based Pharmacokinetic Model.

B. Fang, Z. Zeng, Yi-Hsien Cheng, 2019, Journal of agricultural and food chemistry.

Machine learning and artificial intelligence in toxicological sciences.

W. Chou, Zhoumeng Lin, 2022, Toxicological sciences : an official journal of the Society of Toxicology.

Machine learning and artificial intelligence in physiologically based pharmacokinetic modeling.

W. Chou, Zhoumeng Lin, 2022, Toxicological sciences : an official journal of the Society of Toxicology.

Bayesian evaluation of a physiologically based pharmacokinetic (PBPK) model for perfluorooctane sulfonate (PFOS) to characterize the interspecies uncertainty between mice, rats, monkeys, and humans: Development and performance verification.

W. Chou, Zhoumeng Lin, 2019, Environment international.

Analgesic Comparison of Flunixin Meglumine or Meloxicam for Soft-Tissue Surgery in Sheep: A Pilot Study

J. Coetzee, A. Viscardi, Zhoumeng Lin, 2021, Animals : an open access journal from MDPI.

An Interactive Generic Physiologically Based Pharmacokinetic (igPBPK) Modeling Platform to Predict Drug Withdrawal Intervals in Cattle and Swine: A Case Study on Flunixin, Florfenicol, and Penicillin G

W. Chou, F. Maunsell, L. Tell, 2022, Toxicological sciences : an official journal of the Society of Toxicology.

Development and application of a population physiologically based pharmacokinetic model for florfenicol and its metabolite florfenicol amine in cattle.

J. Riviere, Fan Yang, Zhoumeng Lin, 2019, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Estimation of residue depletion of cyadox and its marker residue in edible tissues of pigs using physiologically based pharmacokinetic modelling

R. Gehring, Lingli Huang, Zonghui Yuan, 2015, Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.

Incorporating Exogenous and Endogenous Exposures into Dietary Risk Assessment of Nitrate and Nitrite in Vegetables: A Probabilistic Integrated Toxicokinetic Modeling Approach.

Yi-Jun Lin, Zhoumeng Lin, Jein-Wen Chen, 2019, Journal of agricultural and food chemistry.

Pharmacokinetics and tumor delivery of nanoparticles.

J. Riviere, Zhoumeng Lin, L. Yuan, 2023, Journal of drug delivery science and technology.

Probabilistic Physiologically Based Pharmacokinetic Model for Penicillin G in Milk From Dairy Cows Following Intramammary or Intramuscular Administrations

R. Gehring, J. Riviere, Zhoumeng Lin, 2018, Toxicological sciences : an official journal of the Society of Toxicology.

A study to assess the correlation between plasma, oral fluid and urine concentrations of flunixin meglumine with the tissue residue depletion profile in finishing-age swine

R. Gehring, J. Coetzee, J. Riviere, 2020, BMC Veterinary Research.

Integration of Food Animal Residue Avoidance Databank (FARAD) empirical methods for drug withdrawal interval determination with a mechanistic population-based interactive physiologically based pharmacokinetic (iPBPK) modeling platform: example for flunixin meglumine administration

Jason T Chittenden, Jennifer L Davis, J. Riviere, 2019, Archives of Toxicology.

Serum Vitamin D Levels and Polycystic Ovary syndrome: A Systematic Review and Meta-Analysis

S. Robb, Zhoumeng Lin, Chunla He, 2015, Nutrients.

Comparative Pharmacokinetics of Sulfadiazine and Its Metabolite N4-Acetyl Sulfadiazine in Grass Carp (Ctenopharyngodon idella) at Different Temperatures after Oral Administration

N. Xu, X. Ai, Zhoumeng Lin, 2022, Pharmaceutics.

Experimental challenges regarding the in vitro investigation of the nanoparticle-biocorona in disease states.

Ran Chen, J. Shannahan, Zhoumeng Lin, 2018, Toxicology in vitro : an international journal published in association with BIBRA.

Short-term atrazine exposure causes behavioral deficits and disrupts monoaminergic systems in male C57BL/6 mice.

N. Filipov, Zhoumeng Lin, C. A. Dodd, 2013, Neurotoxicology and teratology.

Time-dependent behavioral, neurochemical, and metabolic dysregulation in female C57BL/6 mice caused by chronic high-fat diet intake

J. Wagner, N. Filipov, Zhoumeng Lin, 2016, Physiology & Behavior.

A computational framework for interspecies pharmacokinetics, exposure and toxicity assessment of gold nanoparticles.

Jim E Riviere, Zhoumeng Lin, Raghuraman Kannan, 2016, Nanomedicine.

Predicting Nanoparticle Delivery to Tumors Using Machine Learning and Artificial Intelligence Approaches

W. Chou, N. Monteiro-Riviere, J. Riviere, 2022, International journal of nanomedicine.

A physiologically based pharmacokinetic model for polyethylene glycol-coated gold nanoparticles of different sizes in adult mice

Jim E Riviere, Zhoumeng Lin, Nancy A Monteiro-Riviere, 2015, Nanotoxicology.

Differentiation state-dependent effects of in vitro exposure to atrazine or its metabolite diaminochlorotriazine in a dopaminergic cell line.

N. Filipov, Zhoumeng Lin, C. A. Dodd, 2013, Life sciences.

Performance Assessment and Translation of Physiologically Based Pharmacokinetic Models From acslX to Berkeley Madonna, MATLAB, and R Language: Oxytetracycline and Gold Nanoparticles As Case Examples.

Jim E Riviere, Zhoumeng Lin, Raymond S H Yang, 2017, Toxicological sciences : an official journal of the Society of Toxicology.

Consequences of fipronil exposure in egg-laying hens.

J. Riviere, L. Tell, Zhoumeng Lin, 2018, Journal of the American Veterinary Medical Association.

Comparative Pharmacokinetics and Tissue Concentrations of Flunixin Meglumine and Meloxicam in Tilapia (Oreochromis spp.)

J. Coetzee, D. Kuhn, G. Magnin, 2021, Fishes.

Tissue residue depletion and estimation of extralabel meat withdrawal intervals for tulathromycin in calves after pneumatic dart administration.

J. Coetzee, Joseph S Smith, L. Wulf, 2019, Journal of animal science.

An integrated experimental and physiologically based pharmacokinetic modeling study of penicillin G in heavy sows.

R. Gehring, J. Coetzee, J. Riviere, 2019, Journal of veterinary pharmacology and therapeutics.

Human Food Safety Implications of Variation in Food Animal Drug Metabolism

Zhoumeng Lin, Jim E. Riviere, Christopher I. Vahl, 2016, Scientific Reports.

Miao Li, Jim E Riviere, Lisa A Tell, 2019, Archives of Toxicology.

Estimation of tulathromycin depletion in plasma and milk after subcutaneous injection in lactating goats using a nonlinear mixed-effects pharmacokinetic modeling approach

R. Gehring, J. Riviere, L. Tell, 2016, BMC Veterinary Research.

Pharmacokinetic Parameters and Estimated Milk Withdrawal Intervals for Domestic Goats (Capra Aegagrus Hircus) After Administration of Single and Multiple Intravenous and Subcutaneous Doses of Flunixin Meglumine

L. Tell, Joe S. Smith, W. Shelver, 2020, Frontiers in Veterinary Science.

Pharmacokinetics, Milk Residues, and Toxicological Evaluation of a Single High Dose of Meloxicam Administered at 30 mg/kg per os to Lactating Dairy Cattle

L. Wulf, Zhoumeng Lin, M. Kleinhenz, 2023, Veterinary sciences.

A history and recent efforts of selected physiologically based pharmacokinetic modeling topics

Zhoumeng Lin, Jeffrey W. Fisher, J. Fisher, 2020 .

Fundamentals of physiologically based pharmacokinetic modeling

Xiaoxia Yang, Jeffrey W. Fisher, Darshan Mehta, 2020 .

Integration of Toxicogenomics and Physiologically Based Pharmacokinetic Modeling in Human Health Risk Assessment of Perfluorooctane Sulfonate.

W. Chou, Zhoumeng Lin, Qiran Chen, 2022, Environmental science & technology.

Zn-based physiometacomposite nanoparticles: distribution, tolerance, imaging, and antiviral and anticancer activity.

R. Mazloom, K. Ghosh, R. Marasini, 2021, Nanomedicine.

Pharmacokinetic Parameters and Estimating Extra-Label Tissue Withdrawal Intervals Using Three Approaches and Various Matrices for Domestic Laying Chickens Following Meloxicam Administration

L. Tell, Zhoumeng Lin, Jennifer L. Davis, 2022, Frontiers in Veterinary Science.

Relative Oral Bioavailability of Two Amoxicillin-Clavulanic Acid Formulations in Healthy Dogs: A Pilot Study.

J. Coetzee, J. Mochel, Zhoumeng Lin, 2019, Journal of the American Animal Hospital Association.

Development of a physiologically based pharmacokinetic model to predict irinotecan disposition during inflammation.

R. Ghose, Zhoumeng Lin, P. Chityala, 2022, Chemico-biological interactions.

Metabolism and physiologically based pharmacokinetic models

J. Fisher, Zhoumeng Lin, J. Campbell, 2020 .

An artificial intelligence-assisted physiologically-based pharmacokinetic model to predict nanoparticle delivery to tumors in mice.

W. Chou, N. Monteiro-Riviere, Yi-Hsien Cheng, 2023, Journal of controlled release : official journal of the Controlled Release Society.

Meta-Analysis of Nanoparticle Distribution in Tumors and Major Organs in Tumor-Bearing Mice

N. Monteiro-Riviere, Zhoumeng Lin, Chunla He, 2023, ACS nano.