K. Salyers

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Preclinical pharmacokinetics and interspecies scaling of a novel vitronectin receptor antagonist.

K. Ward, B. R. Smith, R. Keenan, 1999, Drug metabolism and disposition: the biological fate of chemicals.

Discovery of orally active nonpeptide vitronectin receptor antagonists based on a 2-benzazepine Gly-Asp mimetic.

K. Ward, K. Erhard, R. Calvo, 2000, Journal of medicinal chemistry.

Urotensin-II receptor antagonists: synthesis and SAR of N-cyclic azaalkyl benzamides.

H. Sarau, J. Foley, N. Aiyar, 2008, Bioorganic & medicinal chemistry letters.

Antagonism of the Osteoclast Vitronectin Receptor with an Orally Active Nonpeptide Inhibitor Prevents Cancellous Bone Loss in the Ovariectomized Rat

K. Ward, B. R. Smith, M. Lark, 2001, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Discovery of a Novel and Potent Class of FabI-Directed Antibacterial Agents

Martha S. Head, Xiayang Qiu, Cheryl A. Janson, 2002, Antimicrobial Agents and Chemotherapy.

Animal Models for Studying Drug Metabolizing Enzymes and Transporters

K. Salyers, Yang Xu, 2012 .

Extraction of octamethylcyclotetrasiloxane and its metabolites from biological matrices.

K. Plotzke, K. Salyers, S. Varaprath, 1998, Analytical biochemistry.

Evaluation of matrix microsampling methods for therapeutic drug candidate quantification in discovery-stage rodent pharmacokinetic studies.

M. Retter, C. James, K. Salyers, 2014, Bioanalysis.

Piperazine oxadiazole inhibitors of acetyl-CoA carboxylase.

M. Fielden, M. Véniant, Minghan Wang, 2013, Journal of medicinal chemistry.

Improvement of the synthesis and pharmacokinetic properties of chromenotriazolopyrimidine MDM2-p53 protein-protein inhibitors.

J. Oliner, S. Olson, Q. Ye, 2011, Bioorganic & medicinal chemistry letters.

Phenylbutyrates as potent, orally bioavailable vitronectin receptor (integrin αvβ3) antagonists

K. Ward, R. Willette, T. Yue, 2003 .

Peptide antagonists of the calcitonin gene-related peptide (CGRP) receptor with improved pharmacokinetics and pharmacodynamics.

C. Gegg, B. H. Manning, L. Miranda, 2013, Biopolymers.

In vitro metabolism of theophylline by rat and human liver tissue.

I. Sipes, K. Salyers, J. Barr, 1994, Xenobiotica; the fate of foreign compounds in biological systems.

Benzofuran Derivatives as Potent, Orally Active S1P1 Receptor Agonists: A Preclinical Lead Molecule for MS.

R. Bürli, M. Lobera, A. Saha, 2011, ACS medicinal chemistry letters.

Identification of potent, selective, and metabolically stable peptide antagonists to the calcitonin gene-related peptide (CGRP) receptor.

C. Gegg, L. Miranda, K. Walker, 2008, Journal of medicinal chemistry.

SB-239063, a Potent and Selective Inhibitor of P38 Map Kinase: Preclinical Pharmacokinetics and Species-Specific Reversible Isomerization

B. Smith, K. Ward, L. M. Azzarano, 2001, Pharmaceutical Research.

Comparison of N,N'-diarylsquaramides and N,N'-diarylureas as antagonists of the CXCR2 chemokine receptor.

K. Ward, H. Sarau, J. Foley, 2007, Bioorganic & medicinal chemistry letters.

SB-242235, a selective inhibitor of p38 mitogenactivated protein kinase. I: Preclinical pharmacokinetics

K. Ward, B. R. Smith, L. M. Azzarano, 2002, Xenobiotica; the fate of foreign compounds in biological systems.

Azepanone-based inhibitors of human and rat cathepsin K.

Y. Ru, D. Veber, K. Ward, 2001, Journal of medicinal chemistry.

Glucuronidation of all-trans-retinoic acid in liposomal membranes.

M. Zile, K. Salyers, M. Cullum, 1993, Biochimica et biophysica acta.

Effect of tetrachlorodibenzo-p-dioxin (TCDD) on the glucuronidation of retinoic acid in the rat.

M. Zile, K. Salyers, P. Bank, 1989, Biochimica et biophysica acta.

Unexpected Thrombocytopenia and Anemia in Cynomolgus Monkeys Induced by a Therapeutic Human Monoclonal Antibody

Riki Stevenson, Erin Stevens, J. Jolette, 2013, Toxicologic pathology.

Pharmaceutical Optimization of Peptide Toxins for Ion Channel Targets: Potent, Selective, and Long-Lived Antagonists of Kv1.3.

J. Sullivan, C. Gegg, J. Werner, 2015, Journal of medicinal chemistry.

Reduced ability of rat preantral ovarian follicles to metabolize 4-vinyl-1-cyclohexene diepoxide in vitro.

J. Flaws, P. Hoyer, I. Sipes, 1994, Toxicology and applied pharmacology.

Identification of metabolites of octamethylcyclotetrasiloxane (D(4)) in rat urine.

K. Plotzke, K. Salyers, S. Varaprath, 1999, Drug metabolism and disposition: the biological fate of chemicals.

Design and characterization of orally active Arg-Gly-Asp peptidomimetic vitronectin receptor antagonist SB 265123 for prevention of bone loss in osteoporosis.

K. Erhard, B. R. Smith, M. Lark, 1999, Journal of Pharmacology and Experimental Therapeutics.

Application of automated serial blood sampling and dried blood spot technique with liquid chromatography-tandem mass spectrometry for pharmacokinetic studies in mice.

Christopher A. James, Philip Wong, Roger Pham, 2011, Journal of pharmaceutical and biomedical analysis.

Unexpected Thrombocytopenia and Anemia in Cynomolgus Monkeys Induced by a Therapeutic Human Monoclonal Antibody

Riki Stevenson, Erin Stevens, J. Jolette, 2013, Toxicologic pathology.