A. Stockis

发表

Local Kinetics and Dynamics of Xenobiotics

A. Boobis, O. Pelkonen, U. Gundert-Remy, 2008, Critical reviews in toxicology.

Physiologically based pharmacokinetic/pharmacodynamic animal-to-man prediction of therapeutic dose in a model of epilepsy.

A. Brochot, A. Stockis, M. Zamacona, 2010, Basic & clinical pharmacology & toxicology.

Effect of levetiracetam on cardiac repolarization in healthy subjects: a single-dose, randomized, placebo- and active-controlled, four-way crossover study.

W. Bridson, D. Rosillon, A. Stockis, 2008, Clinical therapeutics.

Time-to-Seizure Modeling of Lacosamide Used in Monotherapy in Patients with Newly Diagnosed Epilepsy

A. Stockis, A. Lindauer, C. Laveille, 2017, Clinical Pharmacokinetics.

Dose–response population analysis of levetiracetam add-on treatment in refractory epileptic patients with partial onset seizures

E. Snoeck, Armel Stockis, A. Stockis, 2007, Epilepsy Research.

The pharmacokinetics of oxybutynin in man

A. Herchuelz, A. Stockis, J. Douchamps, 2004, European Journal of Clinical Pharmacology.

Effect of brivaracetam on CYP3A activity, measured by oral midazolam

A. Scheen, A. Stockis, Shikiko Watanabe, 2015, Journal of clinical pharmacology.

Levocetirizine does not prolong the QT/QTc interval in healthy subjects: results from a thorough QT study

D. Rosillon, A. Stockis, R. Hulhoven, 2007, European Journal of Clinical Pharmacology.

Nitazoxanide pharmacokinetics and tolerability in man using single ascending oral doses.

A. Stockis, S. De Bruyn, A. Allemon, 2002, International journal of clinical pharmacology and therapeutics.

Pharmacokinetics and metabolism of [14C]-tozadenant (SYN-115), a novel A2a receptor antagonist ligand, in healthy volunteers

M. Bani, A. Stockis, M. Croft, 2017, Xenobiotica; the fate of foreign compounds in biological systems.

Levetiracetam Pharmacokinetics in Japanese Subjects with Renal Impairment

Y. Kumagai, A. Stockis, J. Yamamoto, 2014, Clinical Drug Investigation.

Pharmacokinetics and Metabolism of 14C-Brivaracetam, a Novel SV2A Ligand, in Healthy Subjects

M. Sargentini-Maier, A. Stockis, A. Coquette, 2008, Drug Metabolism and Disposition.

SV2a Ligand, in Healthy Subjects

M. Sargentini-Maier, A. Stockis, A. Coquette, 2007 .

Extrapolation of a Brivaracetam Exposure–Response Model from Adults to Children with Focal Seizures

J. Wade, R. Schoemaker, A. Stockis, 2017, Clinical Pharmacokinetics.

Brivaracetam Disposition in Mild to Severe Hepatic Impairment

Y. Horsmans, M. Sargentini-Maier, A. Stockis, 2013, Journal of clinical pharmacology.

Comparative bioavailability of a metoprolol controlled release formulation and a bisoprolol normal release tablet after single oral dose administration in healthy volunteers.

R. Lins, A. Stockis, S. Lens, 1996, International journal of clinical pharmacology and therapeutics.

A single‐center, open‐label positron emission tomography study to evaluate brivaracetam and levetiracetam synaptic vesicle glycoprotein 2A binding in healthy volunteers

R. P. Maguire, P. Muglia, Yiyun Huang, 2019, Epilepsia.

Prospective assessment of levetiracetam pharmacokinetics during dose escalation in 4- to 12-year-old children with partial-onset seizures on concomitant carbamazepine or valproate

N. Fountain, J. Conry, Ildefonso Rodríguez-Leyva, 2007, Epilepsy Research.

Levetiracetam Intravenous Infusion as an Alternative to Oral Dosing in Patients with Partial‐Onset Seizures

C. Elger, M. Baulac, K. Krakow, 2007, Epilepsia.

Levetiracetam Intravenous Infusion: A Randomized, Placebo‐controlled Safety and Pharmacokinetic Study

S. Ramael, A. Stockis, C. Otoul, 2006, Epilepsia.

Single-dose bioavailability of levetiracetam intravenous infusion relative to oral tablets and multiple-dose pharmacokinetics and tolerability of levetiracetam intravenous infusion compared with placebo in healthy subjects.

S. Ramael, A. Stockis, C. Otoul, 2006, Clinical therapeutics.

A review of the drug−drug interactions of the antiepileptic drug brivaracetam

B. Gidal, A. Stockis, J. Nicolas, 2020, Epilepsy Research.

Brivaracetam-induced elevation of carbamazepine epoxide levels: A post-hoc analysis from the clinical development program

M. Brodie, T. Fakhoury, A. Colson, 2018, Epilepsy Research.

Brivaracetam Population Pharmacokinetics and Exposure‐Response Modeling in Adult Subjects With Partial‐Onset Seizures

J. Wade, R. Schoemaker, A. Stockis, 2016, Journal of clinical pharmacology.

Lack of effect of lacosamide on the pharmacokinetic and pharmacodynamic profiles of warfarin

W. Cawello, A. Stockis, K. Eckhardt, 2013, Epilepsia.

Hindered rotation and electronic distribution in thiocarbamates

P. Laszlo, A. Stockis, J. Jadot, 1976 .

Pharmacokinetics of brodimoprim in special populations.

F. Gaspari, R. Lins, D. Rosillon, 1993, Journal of chemotherapy.

Drug characteristics derived from kinetic modeling: combined 11C-UCB-J human PET imaging with levetiracetam and brivaracetam occupancy of SV2A

R. P. Maguire, Yiyun Huang, R. Carson, 2022, EJNMMI Research.

Brivaracetam single and multiple rising oral dose study in healthy Japanese participants: influence of CYP2C19 genotype.

S. Irie, A. Stockis, K. Matsuguma, 2014, Drug metabolism and pharmacokinetics.

Metallacyclopentanes and bisolefin complexes

R. Hoffmann, A. Stockis, 1980 .

Nickelacyclopentane complexes. A theoretical investigation

R. Hoffmann, D. Thorn, A. Stockis, 1981 .

A molecular orbital analysis of the bonding capabilities of carbon disulfide and carbon dioxide toward transition-metal fragments

R. Hoffmann, C. Mealli, A. Stockis, 1984 .

Oral bioavailability of CHF1194, an inclusion complex of piroxicam and β-cyclodextrin, in healthy subjects under single dose and steady-state conditions

P. Ventura, A. Stockis, D. Acerbi, 2004, European Journal of Clinical Pharmacology.

Likert Pain Score Modeling: A Markov Integer Model and an Autoregressive Continuous Model

M O Karlsson, M. Karlsson, E. Plan, 2012, Clinical pharmacology and therapeutics.

Nitazoxanide pharmacokinetics and tolerability in man during 7 days dosing with 0.5 g and 1 g b.i.d.

D. Rosillon, A. Stockis, S. De Bruyn, 2002, International journal of clinical pharmacology and therapeutics.

Nitazoxanide: pharmacokinetics and metabolism in man.

R. Lins, A. Stockis, J. Broekhuysen, 2000, International journal of clinical pharmacology and therapeutics.

Pharmacokinetics of nitazoxanide after single oral dose administration in 6 healthy volunteers.

R. Lins, A. Stockis, J. Rossignol, 1996, International journal of clinical pharmacology and therapeutics.

Cobalt-59 NMR as a sensitive probe into hydrophobic effects

P. Laszlo, A. Delville, A. Stockis, 1981 .

Clinical pharmacology of levetiracetam for the treatment of epilepsy

A. Stockis, C. Otoul, S. Lu, 2009, Expert review of clinical pharmacology.

Retrospective Population Pharmacokinetic Analysis of Levetiracetam in Children and Adolescents with Epilepsy

P. Jacqmin, B. Lacroix, A. Stockis, 2008, Clinical pharmacokinetics.

Effect of brivaracetam (400 mg/day) on the pharmacokinetics and pharmacodynamics of a combination oral contraceptive in healthy women

P. Rolan, A. Stockis, 2013, Journal of clinical pharmacology.

The pharmacokinetics, CNS pharmacodynamics and adverse event profile of brivaracetam after single increasing oral doses in healthy males.

P. Rolan, D. Tytgat, A. Stockis, 2007, British journal of clinical pharmacology.

Brivaracetam, a selective high‐affinity synaptic vesicle protein 2A (SV2A) ligand with preclinical evidence of high brain permeability and fast onset of action

Richard E Carson, Nabeel Nabulsi, Daniel Holden, 2016, Epilepsia.

Off-line solid phase extraction and liquid chromatography-tandem mass spectrometry method for the quantitation of brivaracetam acid metabolites: Method validation and application to in vitro metabolism assays.

A. Stockis, J. Nicolas, H. Chanteux, 2018, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Levetiracetam: Relative Bioavailability and Bioequivalence of a 10% Oral Solution (750 mg) and 750‐mg Tablets

A. Stockis, Roel Straetemans, Z. Lu, 2003, Journal of clinical pharmacology.

Prospective Open-Label, Single-Arm, Multicenter, Safety, Tolerability, and Pharmacokinetic Studies of Intravenous Levetiracetam in Children With Epilepsy

Y. Karmon, A. Stockis, O. Farooq, 2013, Journal of child neurology.

Brivaracetam and carbamazepine interaction in healthy subjects and in vitro

P. Rolan, A. Stockis, H. Chanteux, 2015, Epilepsy Research.

Interaction between brivaracetam (100 mg/day) and a combination oral contraceptive: A randomized, double‐blind, placebo‐controlled study

N. Fauchoux, A. Stockis, S. Watanabe, 2014, Epilepsia.

Advances in epilepsy treatment: lacosamide pharmacokinetic profile

W. Cawello, J. Andreas, S. Dimova, 2014, Annals of the New York Academy of Sciences.

Lack of Pharmacokinetic Interaction of Levetiracetam on Carbamazepine, Valproic Acid, Topiramate, and Lamotrigine in Children with Epilepsy

A. Stockis, C. Otoul, H. De Smedt, 2007, Epilepsia.

Pharmacokinetics of Levetiracetam in Infants and Young Children with Epilepsy

T. Glauser, M. Bebin, A. Stockis, 2007, Epilepsia.

Direct NMR Studies of Ionic Solvation

P. Laszlo, C. Detellier, A. Delville, 1980 .

On the stability and lability of a dieneiron tricarbonyl complex

P. Laszlo, J. Lallemand, A. Stockis, 1975 .

Pharmacokinetic profile of a new controlled-release isosorbide-5-mononitrate 60 mg scored tablet (Monoket Multitab).

A. Stockis, S. De Bruyn, G. Poli, 2002, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Retrospective population pharmacokinetics of levocetirizine in atopic children receiving cetirizine: the ETAC study.

L. Aarons, M. de Longueville, A. Stockis, 2005, British journal of clinical pharmacology.

Retrospective population pharmacokinetic analysis of cetirizine in children aged 6 months to 12 years.

L. Aarons, M. de Longueville, A. Stockis, 2003, British journal of clinical pharmacology.

Brivaracetam population pharmacokinetics in children with epilepsy aged 1 month to 16 years

J. Wade, R. Schoemaker, A. Stockis, 2017, European Journal of Clinical Pharmacology.

Safety and Tolerability of Adjunctive Brivaracetam in Pediatric Patients < 16 Years with Epilepsy: An Open-Label Trial

A. Stockis, T. Daniels, Belinda McDonough, 2019, Pediatric Drugs.

The pharmacokinetics, CNS pharmacodynamics and adverse event profile of brivaracetam after multiple increasing oral doses in healthy men.

P. Rolan, A. Stockis, E. Pigeolet, 2008, British journal of clinical pharmacology.

Pharmacokinetic interaction of brivaracetam on other antiepileptic drugs in adults with focal seizures: Pooled analysis of data from randomized clinical trials

A. Stockis, C. Otoul, B. Moseley, 2019, Epilepsy Research.

Evaluation of brivaracetam efficacy as monotherapy in adult patients with focal seizures

J. Wade, R. Schoemaker, A. Stockis, 2017, Epilepsy Research.

Relative Bioavailability and Bioequivalence of Brivaracetam 10 mg/mL Oral Solution and 50‐mg Film‐Coated Tablet

A. Stockis, C. Otoul, Suzanne McCabe, 2016, Clinical pharmacology in drug development.

Bioavailability and bioequivalence comparison of brivaracetam 10, 50, 75, and 100 mg tablets and 100 mg intravenous bolus

A. Stockis, S. Hadi, J. Hartstra, 2016, Epilepsia.

Population Pharmacokinetics of Levetiracetam in Japanese and Western Adults

P. Jacqmin, A. Stockis, E. Pigeolet, 2007, Clinical pharmacokinetics.

Assessment of a white matter reference region for 11C-UCB-J PET quantification

Richard E Carson, Nabeel Nabulsi, Mika Naganawa, 2020, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

23Na N.M.R. and ab initio studies of sodium cation solvation by a nitroxide radical

P. Laszlo, A. Stockis, W. Kołodziejski, 1982 .

Brivaracetam Disposition in Renal Impairment

A. Stockis, P. Boulanger, A. Sokalski, 2012, Journal of clinical pharmacology.

Local kinetics and dynamics of xenobiotics.

A. Boobis, O. Pelkonen, U. Gundert-Remy, 2008, Critical reviews in toxicology.

Single Oral Dose Pharmacokinetic Interaction Study of Manidipine and Delapril in Healthy Volunteers

A. Stockis, F. Goethals, G. Poli, 2003, Arzneimittelforschung.

A European approach to clinical investigator training

B. Hirst, J. Boeynaems, C. Canivet, 2013, Front. Pharmacol..

Modeling and simulation for the evaluation of dose adaptation rules of intravenous lacosamide in children

R. Schoemaker, J. Winkler, A. Stockis, 2019, Epilepsy Research.

Population Pharmacokinetics of Adjunctive Lacosamide in Pediatric Patients With Epilepsy

R. Schoemaker, J. Winkler, A. Stockis, 2018, Journal of clinical pharmacology.

Assessment of levetiracetam bioavailability from targeted sites in the human intestine using remotely activated capsules and gamma scintigraphy: Open-label, single-dose, randomized, four-way crossover study in healthy male volunteers.

I. Wilding, A. Connor, A. Stockis, 2010, Clinical therapeutics.

Pharmacological interactions between brivaracetam and ethanol in healthy males

J. V. van Gerven, M. D. de Kam, J. Stevens, 2017, Journal of psychopharmacology.

Pharmacokinetics, Safety and Bioequivalence of Levetiracetam Intravenous Infusion and Oral Tablets in Healthy Chinese Subjects

Qian Chen, A. Stockis, Xinlu Du, 2015, Clinical Drug Investigation.

Effect of Rifampin on the Disposition of Brivaracetam in Human Subjects: Further Insights into Brivaracetam Hydrolysis

A. Scheen, D. Tytgat, A. Stockis, 2016, Drug Metabolism and Disposition.

Food effect on the oral bioavailability of Manidipine: single dose, randomized, crossover study in healthy male subjects

R. Lins, D. Rosillon, A. Stockis, 1998, European Journal of Drug Metabolism and Pharmacokinetics.

Pharmacokinetics, Safety, and Tolerability of Brivaracetam in Healthy Elderly Participants.

W. Krauwinkel, A. Stockis, J. Nicolas, 2023, Clinical pharmacology in drug development.

Bioavailability, safety and tolerability of intravenous brivaracetam in healthy Japanese participants

A. Stockis, J. Yamamoto, K. Ikeda, 2022, Xenobiotica; the fate of foreign compounds in biological systems.

Relative bioavailability of carbinoxamine and phenylephrine from a retard capsule after single and repeated dose administration in healthy subjects.

R. Lins, A. Stockis, A. Allemon, 1995, Arzneimittel-Forschung.

Pharmacokinetics of nitazoxanide after single oral dose administration: pilot study in 6 healthy volunteers

R. Lins, A. Stockis, P. Calderón, 1996 .

Comparison of plasma and saliva concentrations of levetiracetam following administration orally as a tablet and as a solution in healthy adult volunteers.

R. Lins, A. Stockis, C. Otoul, 2007, International journal of clinical pharmacology and therapeutics.

Modeling and simulation of intravenous levetiracetam pharmacokinetic profiles in children to evaluate dose adaptation rules

P. Jacqmin, E. Snoeck, A. Stockis, 2007, Epilepsy Research.

A Pharmacodynamic Markov Mixed‐Effects Model for Determining the Effect of Exposure to Certolizumab Pegol on the ACR20 Score in Patients With Rheumatoid Arthritis

L E Friberg, M O Karlsson, M. Karlsson, 2009, Clinical pharmacology and therapeutics.

Metal assisted ring expansions. Stereospecific expansion of pinene induced by iron pentacarbonyl

A. Stockis, E. Weissberger, 1975 .

METAL ASSISTED RING EXPANSIONS, THE STEREOSPECIFIC EXPANSION OF PINENE INDUCED BY FE(CO)5

A. Stockis, E. Weissberger, 1975 .

Pharmacokinetics and Tolerability of a New Manidipine and Delapril Fixed Oral Combination in Young and Elderly Subjects

A. Stockis, F. Goethals, G. Poli, 2003, Arzneimittelforschung.

Brivaracetam Disposition in Renal Impairment

A. Stockis, P. Boulanger, A. Sokalski, 2012, Journal of clinical pharmacology.

Evaluation of brivaracetam, a novel SV2A ligand, in the photosensitivity model

B. Steinhoff, P. Genton, D. Kasteleijn-Nolst Trenité, 2007, Neurology.

Effect of levetiracetam on cardiac repolarization in healthy subjects: a single-dose, randomized, placebo- and active-controlled, four-way crossover study.

W. Bridson, D. Rosillon, A. Stockis, 2008, Clinical therapeutics.

Pharmacokinetic interaction of brivaracetam on carbamazepine in adult patients with epilepsy, with and without valproate co-administration

M. Brodie, A. Stockis, M. Sargentini‐Maier, 2016, Epilepsy Research.

Effect of Gemfibrozil on the Metabolism of Brivaracetam In Vitro and in Human Subjects

A. Stockis, J. Nicolas, H. Chanteux, 2012, Drug Metabolism and Disposition.

Brivaracetam Disposition in Mild to Severe Hepatic Impairment

Y. Horsmans, A. Stockis, M. Sargentini‐Maier, 2013, Journal of clinical pharmacology.

Pharmacokinetics of levetiracetam XR 500mg tablets

A. Stockis, I. Burton, E. Rouits, 2009, Epilepsy Research.