F. Albertioni

发表

Thiopurines: factors influencing toxicity and response.

S. Coulthard, A. Fotoohi, F. Albertioni, 2010, Biochemical pharmacology.

Mechanisms of antifolate resistance and methotrexate efficacy in leukemia cells

A. Fotoohi, F. Albertioni, Alan Kambiz Fotoohi, 2008, Leukemia & lymphoma.

Gene expression profiling of leukemia T-cells resistant to methotrexate and 7-hydroxymethotrexate reveals alterations that preserve intracellular levels of folate and nucleotide biosynthesis.

G. Peters, C. Larsson, Y. Assaraf, 2009, Biochemical pharmacology.

Mechanisms of anti-cancer action and pharmacology of clofarabine.

G. Juliusson, F. Albertioni, A. Zhenchuk, 2009, Biochemical pharmacology.

In vitro topo II--DNA complex accumulation and cytotoxicity of etoposide in leukaemic cells from patients with acute myelogenous and chronic lymphocytic leukaemia.

A. Gruber, J. Liliemark, F. Albertioni, 2001, Leukemia research.

Methotrexate plasma pharmacokinetics: importance of assay method.

S. Eksborg, C. Peterson, O. Beck, 1996, Cancer letters.

Molecular and biochemical mechanisms of fludarabine and cladribine resistance in a human promyelocytic cell line.

S. Eriksson, F. Albertioni, T. Spasokoukotskaja, 1999, Cancer research.

Resistance of leukemic cells to 2-chlorodeoxyadenosine is due to a lack of calcium-dependent cytochrome c release.

V. Gogvadze, S. Orrenius, S. Kaufmann, 2002, Blood.

Biochemical pharmacology and resistance to 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine, a novel analogue of cladribine in human leukemic cells.

S. Eriksson, C. Peterson, J. Liliemark, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

Controlled trial of methotrexate in patients with severe chronic asthma

F. Albertioni, J. Hedman, P. Seideman, 1996, European Journal of Clinical Pharmacology.

Differences in cytosolic and mitochondrial 5'-nucleotidase and deoxynucleoside kinase activities in Sprague-Dawley rat and CD-1 mouse tissues: implication for the toxicity of nucleoside analogs in animal models.

S. Eriksson, F. Albertioni, S. Mirzaee, 2010, Toxicology.

Cytotoxicity and pharmacokinetics of cladribine metabolite, 2-chloroadenine in patients with leukemia.

G. Juliusson, R. Larsson, J. Liliemark, 2004, Cancer letters.

Interference of 7-hydroxymethotrexate with the determination of methotrexate in plasma samples from children with acute lymphoblastic leukemia employing routine clinical assays.

C. Peterson, S. Söderhäll, F. Albertioni, 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Clinical and pharmacokinetic risk factors for high-dose methotrexate-induced toxicity in children with acute lymphoblastic leukemia--a logistic regression analysis.

S. Bentzen, C. Peterson, S. Bentzen, 1998, Acta oncologica.

Oral mucositis in children with acute lymphoblastic leukemia after high-dose methotrexate treatment without delayed elimination of methotrexate: relation to pharmacokinetic parameters of methotrexate.

C. Peterson, F. Albertioni, C. Rask, 1996, Pediatric hematology and oncology.

Real-time quantitative PCR assays for deoxycytidine kinase, deoxyguanosine kinase and 5’-nucleotidase mRNA measurement in cell lines and in patients with leukemia

G. Gustafsson, S. Eriksson, S. Söderhäll, 2002, Leukemia.

Regulation of p53R2 and its role as potential target for cancer therapy.

X. Wang, K. Wiman, F. Albertioni, 2009, Cancer letters.

Pharmacological Basis for Cladribine Resistance

G. Juliusson, F. Albertioni, K. Lotfi, 2003, Leukemia & lymphoma.

Mechanisms of cross-resistance between nucleoside analogues and vincristine or daunorubicin in leukemic cells.

S. Eriksson, F. Albertioni, K. Lotfi, 2004, Biochemical and biophysical research communications.

Differences Between Children and Adults in Thiopurine Methyltransferase Activity and Metabolite Formation During Thiopurine Therapy: Possible Role of Concomitant Methotrexate

C. Peterson, S. Söderhäll, B. Pettersson, 2002, Therapeutic drug monitoring.

Treatment of normal and malignant cells with nucleoside analogues and etoposide enhances deoxycytidine kinase activity.

G. Keszler, S. Eriksson, F. Albertioni, 1999, European journal of cancer.

Activation of Deoxycytidine Kinase by Various Nucleoside Analogues

S. Eriksson, F. Albertioni, T. Spasokoukotskaja, 1998 .

Low-dose oral pulse methotrexate as monotherapy in elderly patients with bullous pemphigoid.

M. Ståhle-Bäckdahl, C. Peterson, I. Vassilaki, 1999, Journal of the American Academy of Dermatology.

Analysis of DNA methylation of the 5' region of the deoxycytidine kinase gene in CCRF-CEM-sensitive and cladribine (CdA)- and 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine (CAFdA)-resistant cells.

R. D. De Abreu, F. Albertioni, P. Leegwater, 1998, Cancer Letters.

On the bioavailability of oral and subcutaneous 2-chloro-2'-deoxyadenosine in humans: alternative routes of administration.

G. Juliusson, Moustapha Hassan, J. Liliemark, 1992, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Hydrophobicity parameters of 2-chloro-2′-deoxyadenosine and some related analogues and retention in reversed-phase liquid chromatography

J. Liliemark, F. Albertioni, V. Reichelová, 1994 .

The pattern of deoxycytidine- and deoxyguanosine kinase activity in relation to messenger RNA expression in blood cells from untreated patients with B-cell chronic lymphocytic leukemia.

G. Juliusson, S. Eriksson, A. Fyrberg, 2006, Biochemical pharmacology.

Activity profiles of deoxynucleoside kinases and 5'-nucleotidases in cultured adipocytes and myoblastic cells: insights into mitochondrial toxicity of nucleoside analogs.

S. Eriksson, F. Albertioni, S. Rylova, 2005, Biochemical pharmacology.

Pharmacological basis for cladribine resistance in a human acute T lymphoblastic leukaemia cell line selected for resistance to etoposide

Dawei Xu, S. Eriksson, F. Albertioni, 2001, British journal of haematology.

Simultaneous quantitation of methotrexate and its two main metabolites in biological fluids by a novel solid-phase extraction procedure using high-performance liquid chromatography.

C. Peterson, O. Beck, B. Pettersson, 1995, Journal of chromatography. B, Biomedical applications.

Reduced DNA ligase activity in etoposide resistant human lymphatic leukaemia CEM cells.

S. Ljungquist, F. Albertioni, E. Liliemark, 2002, Biochemical pharmacology.

High Activity and Incomplete Cross Resistance of Nucleoside Analogues Cladribine and Fludarabine Versus Ara-C on Leukemic Cells From Patients With AML

F. Albertioni, C. Paul, C. Löfgren, 2005, Therapeutic drug monitoring.

Comparison of cytotoxicity of 2-chloro- 2'-arabino-fluoro-2'-deoxyadenosine (clofarabine) with cladribine in mononuclear cells from patients with acute myeloid and chronic lymphocytic leukemia.

Staffan Eriksson, Mats O Karlsson, Synnöve Lindemalm, 2003, Haematologica.

Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance.

S. Eriksson, S. Lagercrantz, J. Liliemark, 2003, Biochemical pharmacology.

Expression of deoxynucleoside kinases and 5'-nucleotidases in mouse tissues: implications for mitochondrial toxicity.

S. Eriksson, F. Albertioni, S. Rylova, 2007, Biochemical pharmacology.

Deoxynucleoside anabolic enzyme levels in acute myelocytic leukemia and chronic lymphocytic leukemia cells.

B. Jacobsson, S. Eriksson, F. Albertioni, 2001, Cancer letters.

Low level of mitochondrial deoxyguanosine kinase is the dominant factor in acquired resistance to 9-beta-D-arabinofuranosylguanine cytotoxicity.

S. Eriksson, C. Peterson, F. Albertioni, 2002, Biochemical and biophysical research communications.

The pattern of gene expression and gene dose profiles of 6-Mercaptopurine- and 6-Thioguanine-resistant human leukemia cells.

C. Larsson, J. Hashemi, A. Moshfegh, 2011, Biochemical and biophysical research communications.

Molecular mechanisms underlying the enhanced sensitivity of thiopurine-resistant T-lymphoblastic cell lines to methyl mercaptopurineriboside.

C. Peterson, A. Moshfegh, A. Fotoohi, 2006, Biochemical pharmacology.

Involvement of the concentrative nucleoside transporter 3 and equilibrative nucleoside transporter 2 in the resistance of T-lymphoblastic cell lines to thiopurines.

C. Peterson, A. Fotoohi, F. Albertioni, 2006, Biochemical and biophysical research communications.

Molecular and biochemical mechanisms of fludarabine and cladribine resistance in a human promyelocytic cell line.

S. Eriksson, F. Albertioni, T. Spasokoukotskaja, 1999, Cancer research.

Liquid chromatographic study of acid stability of 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine, 2-chloro-2'-deoxyadenosine and related analogues.

J. Liliemark, F. Albertioni, V. Reichelová, 1995, Journal of pharmaceutical and biomedical analysis.

Cross‐resistance to cytosine arabinoside in a multidrug‐resistant human promyelocytic cell line selected for resistance to doxorubicin: implications for combination chemotherapy

S. Eriksson, F. Albertioni, C. Paul, 2001, British journal of haematology.

Structure-Activity Relationships of 2-Chloro-2′-arabino-fluoro-2′-deoxyadenosine and Related Analogues: Protein Binding, Lipophilicity, and Retention in Reversed-Phase LC

J. Liliemark, F. Albertioni, V. Reichelová, 1995 .

Identification and characterization of human deoxyguanosine kinase cDNA fragments.

F. Albertioni, E. Månsson, K. Jönsson, 2001, Cancer letters.

RNAi Depletion of Deoxycytidine and Deoxyguanosine Kinase in Human Leukemic CEM Cells

A. Fyrberg, F. Albertioni, K. Lotfi, 2008, Nucleosides, nucleotides & nucleic acids.

Cell cycle effect on the activity of deoxynucleoside analogue metabolising enzymes.

A. Fyrberg, F. Albertioni, K. Lotfi, 2007, Biochemical and biophysical research communications.

Resistance to mitochondrial- and Fas-mediated apoptosis in human leukemic cells with acquired resistance to 9-beta-D-arabinofuranosylguanosine.

F. Albertioni, E. Månsson, H. Stridh, 2002, Biochemical and biophysical research communications.

Pharmacokinetics of cladribine in plasma and its 5'-monophosphate and 5'-triphosphate in leukemic cells of patients with chronic lymphocytic leukemia.

G. Juliusson, S. Eriksson, J. Liliemark, 1998, Clinical cancer research : an official journal of the American Association for Cancer Research.

Bioavailability and bacterial degradation of rectally administered 2-chloro-2'-deoxyadenosine.

G. Juliusson, J. Liliemark, F. Albertioni, 1995, Journal of pharmaceutical and biomedical analysis.

Multidrug resistance (Mdr1) gene expression in peripheral blasts from patients with acute leukemia only rarely increases during disease progression after combination chemotherapy.

M. Björkholm, S. Vitols, C. Peterson, 1995, Leukemia & lymphoma.

Evaluation of clinical assays for measuring high-dose methotrexate in plasma.

S. Eksborg, J. Poulsen, C. Peterson, 1996, Clinical chemistry.

Disparate mechanisms of antifolate resistance provoked by methotrexate and its metabolite 7-hydroxymethotrexate in leukemia cells: implications for efficacy of methotrexate therapy.

G. Peters, Y. Assaraf, G. Jansen, 2004, Blood.

Analysis of Azathioprine and 6-Mercaptopurine in Plasma in Renal Transplant Recipients After Administration with Oral Azathioprine

S. Ohlman, C. Peterson, B. Pettersson, 1995 .

A late exclusion of bacteriophage T4 can be suppressed by Escherichia coli GroEL or Rho.

C. Påhlson, K. Carlson, F. Albertioni, 1994, Genetics.

Subcutaneous injections of 2-chlorodeoxyadenosine for symptomatic hairy cell leukemia.

G. Juliusson, G. Tjønnfjord, M. Hedenus, 1995, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Distribution of 2-chloro-2′-deoxyadenosine, 2-chloro-2′-arabino-fluoro-2′-deoxyadenosine, Fludarabine and Cytarabine in mice: a whole-body autoradiography study

J. Liliemark, F. Albertioni, S. Lindemalm, 1999, Medical oncology.

Urine and plasma pharmacokinetics of codeine in healthy volunteers: implications for drugs-of-abuse testing.

O. Beck, P. Lafolie, F. Albertioni, 1996, Journal of analytical toxicology.

Chloroquine reduces the bioavailability of methotrexate in patients with rheumatoid arthritis. A possible mechanism of reduced hepatotoxicity.

S. Eksborg, C. Peterson, O. Beck, 1994, Arthritis and rheumatism.

A limited sampling strategy for estimation of the cladribine plasma area under the concentration versus time curve after intermittent i.v. infusion, s.c. injection, and oral administration

G. Juliusson, S. Eksborg, J. Liliemark, 1996, Cancer Chemotherapy and Pharmacology.

On the bioavailability of 2-chloro-2′-deoxyadenosine (CdA)

G. Juliusson, J. Liliemark, F. Albertioni, 1993, European Journal of Clinical Pharmacology.

Impaired Transport as a Mechanism of Resistance to Thiopurines in Human T-Lymphoblastic Leukemia Cells

C. Peterson, A. Fotoohi, F. Albertioni, 2006, Nucleosides, nucleotides & nucleic acids.

Application of population pharmacokinetics to cladribine

Mats O Karlsson, Gunnar Juliusson, Synnöve Lindemalm, 2005, BMC pharmacology.

Methotrexate in juvenile rheumatoid arthritis

S. Eksborg, C. Peterson, O. Beck, 1995, European Journal of Clinical Pharmacology.

Determination of 2-chloro-2'-deoxyadenosine nucleotides in leukemic cells by ion-pair high-performance liquid chromatography.

J. Liliemark, F. Albertioni, V. Reichelová, 1996, Journal of chromatography. B, Biomedical applications.

Stability and analysis of 2-chloro-2'-deoxyadenosine, 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine and 2-chloroadenine in human blood plasma.

J. Liliemark, F. Albertioni, S. Lindemalm, 1997, Anti-cancer drugs.

Monitoring of methotrexate and 7-hydroxymethotrexate in saliva from children with acute lymphoblastic leukemia receiving high-dose consolidation treatment: relation to oral mucositis.

C. Peterson, F. Albertioni, H. Schroeder, 1997, Anti-cancer drugs.

Activation of deoxycytidine kinase by various nucleoside analogues.

S. Eriksson, F. Albertioni, T. Spasokoukotskaja, 1997, Advances in experimental medicine and biology.

Protein binding of 2-chloro 2′-deoxyadenosine (cladribine) in healthy subjects and in patients with leukaemia

L. Herngren, G. Juliusson, J. Liliemark, 2004, European Journal of Clinical Pharmacology.

Multidrug resistance gene (mdr1) RNA levels in relation to P-glycoprotein content of leukemic cells from patients with acute leukemia

S. Vitols, I. Areström, A. Gruber, 1995, Medical oncology.

Therapeutic drug monitoring of methotrexate on the pediatric oncology ward: can blood sampling from central venous accesses substitute for capillary finger punctures?

S. Eksborg, S. Söderhäll, F. Albertioni, 2007, Therapeutic drug monitoring.

RNAi Depletion of Deoxycytidine and Deoxyguanosine Kinase in Human Leukemic CEM Cells

A. Fyrberg, F. Albertioni, K. Lotfi, 2008, Nucleosides, nucleotides & nucleic acids.

Application of population pharmacokinetics to cladribine

G. Juliusson, R. Savic, M. Karlsson, 2005, BMC pharmacology.