S. Wesseling

发表

Incorporating renal excretion via the OCT2 transporter in physiologically based kinetic modelling to predict in vivo kinetics of mepiquat in rat.

B. van Ravenzwaay, I. Rietjens, Annelies Noorlander, 2021, Toxicology letters.

Determination and risk assessment of naturally occurring genotoxic and carcinogenic alkenylbenzenes in basil-containing sauce of pesto

J. Vervoort, I. Rietjens, S. Wesseling, 2016, Toxicology reports.

Estragole DNA adduct accumulation in human liver HepaRG cells upon repeated in vitro exposure.

I. Rietjens, S. Wesseling, Shuo Yang, 2020, Toxicology letters.

Defining in vivo dose‐response curves for kidney DNA adduct formation of aristolochic acid I in rat, mouse and human by an in vitro and physiologically based kinetic modeling approach

I. Rietjens, J. Louisse, A. Punt, 2020, Journal of applied toxicology : JAT.

Study on inter-ethnic human differences in bioactivation and detoxification of estragole using physiologically based kinetic modeling

I. Rietjens, J. Louisse, J. Ning, 2017, Archives of Toxicology.

Use of an in vitro–in silico testing strategy to predict inter-species and inter-ethnic human differences in liver toxicity of the pyrrolizidine alkaloids lasiocarpine and riddelliine

I. Rietjens, J. Louisse, J. Ning, 2019, Archives of Toxicology.

Use of physiologically based kinetic modelling-facilitated reverse dosimetry to convert in vitro cytotoxicity data to predicted in vivo liver toxicity of lasiocarpine and riddelliine in rat.

I. Rietjens, J. Louisse, J. Ning, 2018, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Hazard assessment of Maerua subcordata (Gilg) DeWolf. for selected endpoints using a battery of in vitro tests.

L. Kamelia, J. Vervoort, I. Rietjens, 2019, Journal of ethnopharmacology.

Natural occurrence of genotoxic and carcinogenic alkenylbenzenes in Indonesian jamu and evaluation of consumer risks.

S. Suparmi, I. Rietjens, S. Wesseling, 2018, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Risk assessment of genotoxic and carcinogenic alkenylbenzenes in botanical containing products present on the Chinese market.

I. Rietjens, J. Ning, S. Wesseling, 2018, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Determination and risk assessment of naturally occurring genotoxic and carcinogenic alkenylbenzenes in nutmeg‐based plant food supplements

J. Vervoort, I. Rietjens, J. Ning, 2017, Journal of applied toxicology : JAT.

Risk assessment of combined exposure to alkenylbenzenes through consumption of plant food supplements containing parsley and dill

J. Vervoort, I. Rietjens, S. Wesseling, 2017, Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.

Level of Alkenylbenzenes in Parsley and Dill Based Teas and Associated Risk Assessment Using the Margin of Exposure Approach.

J. Vervoort, I. Rietjens, S. Wesseling, 2016, Journal of agricultural and food chemistry.

Induction of peroxisome proliferator activated receptor γ (PPARγ) mediated gene expression and inhibition of induced nitric oxide production by Maerua subcordata (Gilg) DeWolf

J. Vervoort, I. Rietjens, S. Wesseling, 2020, BMC Complementary Medicine and Therapies.

Physiologically Based Kinetic Modeling-Facilitated Reverse Dosimetry to Predict In Vivo Red Blood Cell Acetylcholinesterase Inhibition Following Exposure to Chlorpyrifos in the Caucasian and Chinese Population

L. Kamelia, I. Rietjens, S. Wesseling, 2019, Toxicological sciences : an official journal of the Society of Toxicology.

Aflatoxin B1 in nixtamalized maize in Mexico; occurrence and accompanying risk assessment

I. Rietjens, S. Wesseling, Ixchel Gilbert Sandoval, 2019, Toxicology reports.

Physiologically based kinetic modelling predicts the in vivo relative potency of riddelliine N-oxide compared to riddelliine in rat to be dose dependent

I. Rietjens, S. Wesseling, F. Widjaja, 2021, Archives of Toxicology.

Risk assessment for pyrrolizidine alkaloids detected in (herbal) teas and plant food supplements

I. Rietjens, P. Mulder, A. Peijnenburg, 2017, Regulatory toxicology and pharmacology : RTP.

The Vascular Endothelial Growth Factor Receptor Inhibitor Sunitinib Causes a Preeclampsia-Like Syndrome With Activation of the Endothelin System

S. Sleijfer, F. Smedts, A. H. van den Meiracker, 2011, Hypertension.

Perinatal Inhibition of NF-KappaB Has Long-Term Antihypertensive and Renoprotective Effects in Fawn-Hooded Hypertensive Rats.

J. Joles, B. Braam, S. Wesseling, 2016, American journal of hypertension.

Beneficial effects of diminished production of hydrogen sulfide or carbon monoxide on hypertension and renal injury induced by NO withdrawal

M. Verhaar, J. Joles, S. Wesseling, 2015, British journal of pharmacology.

Perinatal Exogenous Nitric Oxide in Fawn-Hooded Hypertensive Rats Reduces Renal Ribosomal Biogenesis in Early Life

P. Essers, A. MacInnes, T. Pereboom, 2011, Front. Gene..

Salt sensitivity of blood pressure: developmental and sex-related effects.

J. Joles, S. Wesseling, M. Koeners, 2011, The American journal of clinical nutrition.

Taurine: red bull or red herring?

J. Joles, S. Wesseling, M. Koeners, 2009, Hypertension.

Commentary Taurine Red Bull or Red Herring ?

J. Joles, S. Wesseling, M. Koeners, 2009 .

Soluble epoxide hydrolase in the generation and maintenance of high blood pressure in spontaneously hypertensive rats.

B. Hammock, C. Morisseau, J. Joles, 2011, American journal of physiology. Endocrinology and metabolism.

hypertensive rats maintenance of high blood pressure in spontaneously Soluble epoxide hydrolase in the generation and

B. Hammock, C. Morisseau, J. Joles, 2011 .

2II in mouse kidney is not mediated by the AT Resistance to oxidative stress by chronic infusion of

H. Bluyssen, J. Joles, D. Ishola, 2016 .

Resistance to oxidative stress by chronic infusion of angiotensin II in mouse kidney is not mediated by the AT2 receptor.

H. Bluyssen, J. Joles, D. Ishola, 2005, American journal of physiology. Renal physiology.

Inter-individual variation in chlorpyrifos toxicokinetics characterized by physiologically based kinetic (PBK) and Monte Carlo simulation comparing human liver microsome and Supersome™ cytochromes P450 (CYP)-specific kinetic data as model input

I. Rietjens, S. Wesseling, M. Strikwold, 2022, Archives of Toxicology.

Identification of phosphodiesterase type-5 (PDE-5) inhibitors in herbal supplements using a tiered approach and associated consumer risk

J. Vervoort, I. Rietjens, R. Hoogenboom, 2022, Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.

oxide-depleted rats antioxidative gene expression in kidney cortex of nitric Transcriptome-based identification of pro- and

F. Holstege, H. Bluyssen, Chien-Te Lee, 2015 .

Transcriptome-based identification of pro- and antioxidative gene expression in kidney cortex of nitric oxide-depleted rats.

P. Kemmeren, F. Holstege, H. Bluyssen, 2007, Physiological Genomics.

DL-propargylglycine reduces blood pressure and renal injury but increases kidney weight in angiotensin-II infused rats.

H. van Goor, R. Giles, M. Verhaar, 2015, Nitric oxide : biology and chemistry.

Differences in gut microbial fructoselysine degradation activity between breast-fed and formula-fed infants

C. Belzer, S. Wesseling, A. Ioannou, 2022, FEMS microbiology ecology.

Maternal Supplementation With Citrulline Increases Renal Nitric Oxide in Young Spontaneously Hypertensive Rats and Has Long-Term Antihypertensive Effects

J. Joles, E. V. van Faassen, H. Koomans, 2007, Hypertension.

Occurrence and Probabilistic Risk Assessment of Fumonisin B1, Fumonisin B2 and Deoxynivalenol in Nixtamalized Maize in Mexico City

I. Rietjens, S. Wesseling, Ixchel Gilbert-Sandoval, 2020, Toxins.

Induction of EpRE-mediated gene expression by a series of mediterranean botanicals and their constituents.

J. Vervoort, I. Rietjens, S. Wesseling, 2019, Journal of ethnopharmacology.

Mode of action based risk assessment of the botanical food-borne alkenylbenzene apiol from parsley using physiologically based kinetic (PBK) modelling and read-across from safrole.

Ivonne M C M Rietjens, Jacques Vervoort, J. Vervoort, 2016, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Levels of methyleugenol and eugenol in instant herbal beverages available on the Indonesian market and related risk assessment.

S. Suparmi, Siti Mariyam, I. Rietjens, 2019, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Physiologically based kinetic modeling of the bioactivation of myristicin

Jacques Vervoort, Ivonne M. C. M. Rietjens, J. Vervoort, 2016, Archives of Toxicology.

Risk assessment of plant food supplements and other herbal products containing aristolochic acids using the margin of exposure (MOE) approach

I. Rietjens, S. Wesseling, Rozaini Abdullah, 2016, Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.

Physiologically based kinetic modelling based prediction of in vivo rat and human acetylcholinesterase (AChE) inhibition upon exposure to diazinon

I. Rietjens, S. Wesseling, B. Spenkelink, 2021, Archives of Toxicology.

Monocrotaline-induced liver toxicity in rat predicted by a combined in vitro physiologically based kinetic modeling approach

S. Suparmi, I. Rietjens, S. Wesseling, 2020, Archives of Toxicology.

The renal transcriptome in experimental hypertension

S. Wesseling, 2007 .

Physiologically based kinetic modeling of senecionine N-oxide in rats as a new approach methodology to define the effects of dose and endpoint used on relative potency values of pyrrolizidine alkaloid N-oxides

I. Rietjens, S. Wesseling, Liang Zheng, 2023, Frontiers in Pharmacology.

Short-Term Erythropoietin Treatment Does Not Substantially Modulate Monocyte Transcriptomes of Patients with Combined Heart and Renal Failure

M. Verhaar, Y. Yasui, P. Doevendans, 2012, PloS one.

In vitro metabolism of naphthalene and its alkylated congeners by human and rat liver microsomes via alkyl side chain or aromatic oxidation.

L. Kamelia, P. Boogaard, I. Rietjens, 2019, Chemico-biological interactions.

Predicting the Acute Liver Toxicity of Aflatoxin B1 in Rats and Humans by an In Vitro–In Silico Testing Strategy

I. Rietjens, S. Wesseling, Ixchel Gilbert-Sandoval, 2020, Molecular nutrition & food research.

A new approach methodology (NAM) for the prediction of (nor)ibogaine-induced cardiotoxicity in humans.

H. Bouwmeester, I. Rietjens, Miaoying Shi, 2021, ALTEX.

Molecular dynamics and in vitro quantification of safrole DNA adducts reveal DNA adduct persistence due to limited DNA distortion resulting in inefficient repair.

C. Oostenbrink, J. Vervoort, I. Rietjens, 2020, Chemical research in toxicology.

IFN gamma-dependent SOCS3 expression inhibits IL-6-induced STAT3 phosphorylation and differentially affects IL-6 mediated transcriptional responses in endothelial cells.

Peter Boer, M. Goumans, H. Bluyssen, 2010, American journal of physiology. Cell physiology.

Cellular levels and molecular dynamics simulations of estragole DNA adducts point at inefficient repair resulting from limited distortion of the double-stranded DNA helix

C. Oostenbrink, J. Vervoort, I. Rietjens, 2020, Archives of Toxicology.

Effects of Maerua subcordata (Gilg) DeWolf on electrophile-responsive element (EpRE)-mediated gene expression in vitro

J. Vervoort, I. Rietjens, J. Louisse, 2019, PloS one.

Consequences of perinatal treatment with l-arginine and antioxidants for the renal transcriptome in spontaneously hypertensive rats

J. Joles, B. Braam, S. Wesseling, 2009, Pflügers Archiv - European Journal of Physiology.

Interindividual Differences in Human Intestinal Microbial Conversion of (−)-Epicatechin to Bioactive Phenolic Compounds

L. Kamelia, J. Vervoort, I. Rietjens, 2020, Journal of agricultural and food chemistry.

On the Role of ROS and Glutathione in the Mode of Action Underlying Nrf2 Activation by the Hydroxyanthraquinone Purpurin

H. Bouwmeester, I. Rietjens, S. Wesseling, 2023, Antioxidants.

Integrating In Vitro Data and Physiologically Based Kinetic Modeling to Predict and Compare Acute Neurotoxic Doses of Saxitoxin in Rats, Mice, and Humans

H. Bouwmeester, N. Kramer, I. Rietjens, 2023, Environmental science & technology.

Selecting the dose metric in reverse dosimetry based QIVIVE

I. Rietjens, J. Louisse, J. Ning, 2019, Archives of Toxicology.

Acetylcholinesterase Inhibition in Rats and Humans Following Acute Fenitrothion Exposure Predicted by Physiologically Based Kinetic Modeling-Facilitated Quantitative In Vitro to In Vivo Extrapolation.

I. Rietjens, S. Wesseling, Shensheng Zhao, 2023, Environmental science & technology.

2016). Perinatal Inhibition of NF-KappaB Has Long-Term Antihypertensive and Renoprotective Effects in Fawn-Hooded Hypertensive Rats. American Journal of Hypertension,

B. Braam, S. Wesseling, M. Koeners, 2022 .