D. Lindley

发表

Mechanistic Physiologically Based Pharmacokinetic Modeling of the Dissolution and Food Effect of a Biopharmaceutics Classification System IV Compound-The Venetoclax Story.

M. Nijsen, Arian Emami Riedmaier, D. Lindley, 2018, Journal of pharmaceutical sciences.

Title Mechanistic PBPK Modeling of the Dissolution and Food Effect of a BCS IV Compound – the Venetoclax Story

M. Nijsen, A. E. Riedmaier, D. Lindley, 2017 .

In vivo preliminary investigations of the effects of the benzimidazole anthelmintic drug flubendazole on rat embryos and fetuses.

T. Geary, C. Mackenzie, M. Longo, 2014, Reproductive toxicology.

The effects of media on pharmaceutically relevant transporters in the human HT-29 adenocarcinoma cell line: does culture media need to be controlled?

G. Knipp, D. Lindley, Stephen M. Carl, 2012, Journal of pharmaceutical sciences.

IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling strategies.

M. Jamei, L. Aarons, M. Bolger, 2020, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Striking the Optimal Solubility-Permeability Balance in Oral Formulation Development for Lipophilic Drugs: Maximizing Carbamazepine Blood Levels.

A. Dahan, Avital Beig, Jonathan M. Miller, 2017, Molecular pharmaceutics.

Toward Successful Cyclodextrin Based Solubility-Enabling Formulations for Oral Delivery of Lipophilic Drugs: Solubility-Permeability Trade-Off, Biorelevant Dissolution, and the Unstirred Water Layer.

A. Dahan, Avital Beig, Jonathan M. Miller, 2017, Molecular pharmaceutics.

1 BIOTECHNOLOGY-DERIVED DRUG PRODUCT DEVELOPMENT

K. Morris, G. Knipp, G. Becker, 2008 .

Evaluation of human peptide/histidine transporter 1 (hPHT1/SLC15A4) function: transport kinetics utilizing a HPHT1 shRNA stably transfected knockdown in the hCMEC/D3 blood-brain barrier cell line

G. Knipp, D. Lindley, Stephen M. Carl, 2021, Pharmacy & Pharmacology International Journal.

ABC AND SLC TRANSPORTER EXPRESSION AND POT SUBSTRATE CHRACTERIZATION ACROSS THE HUMAN CMEC/ D3 BLOOD-BRAIN BARRIER CELL LINE

P. Couraud, G. Knipp, B. Weksler, 2010 .

Concomitant solubility‐permeability increase: Vitamin E TPGS vs. amorphous solid dispersion as oral delivery systems for etoposide

A. Dahan, Avital Beig, Jonathan M. Miller, 2017, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Advantageous Solubility-Permeability Interplay When Using Amorphous Solid Dispersion (ASD) Formulation for the BCS Class IV P-gp Substrate Rifaximin: Simultaneous Increase of Both the Solubility and the Permeability

A. Dahan, Avital Beig, Jonathan M. Miller, 2017, The AAPS Journal.

Hydrotropic Solubilization of Lipophilic Drugs for Oral Delivery: The Effects of Urea and Nicotinamide on Carbamazepine Solubility–Permeability Interplay

A. Dahan, Avital Beig, R. Agbaria, 2016, Front. Pharmacol..

The solubility-permeability interplay and oral drug formulation design: Two heads are better than one.

A. Dahan, Avital Beig, Jonathan M. Miller, 2016, Advanced drug delivery reviews.

Head-To-Head Comparison of Different Solubility-Enabling Formulations of Etoposide and Their Consequent Solubility-Permeability Interplay.

A. Dahan, Avital Beig, R. Agbaria, 2015, Journal of pharmaceutical sciences.

The effects of excipients on transporter mediated absorption.

Jean-Michel Kauffmann, Jonathan Goole, Karim Amighi, 2010, International journal of pharmaceutics.

Drug Transporters and Their Role in Absorption and Disposition of Peptides and Peptide‐Based Pharmaceuticals

G. Knipp, Li Pan, D. Lindley, 2011 .