Jiansong Yang

发表

The Constraints, Construction, and Verification of a Strain-Specific Physiologically Based Pharmacokinetic Rat Model.

Masoud Jamei, David B Turner, Amin Rostami-Hodjegan, 2017, Journal of pharmaceutical sciences.

Kinetic values for mechanism-based enzyme inhibition: assessing the bias introduced by the conventional experimental protocol.

M. Jamei, G. Tucker, A. Rostami-Hodjegan, 2005, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Theoretical assessment of a new experimental protocol for determining kinetic values describing mechanism (time)-based enzyme inhibition.

M. Jamei, G. Tucker, A. Rostami-Hodjegan, 2007, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Anti‐IL‐7 receptor α monoclonal antibody (GSK2618960) in healthy subjects – a randomized, double‐blind, placebo‐controlled study

A. Coles, S. McHugh, Sara Santos Franco, 2018, British journal of clinical pharmacology.

The Consequences of 3,4-Methylenedioxymethamphetamine Induced CYP2D6 Inhibition in Humans

G. Tucker, E. Cuyás, R. de la Torre, 2008, Journal of clinical psychopharmacology.

Population-Based Mechanistic Prediction of Oral Drug Absorption

Sebastian Polak, Masoud Jamei, Amin Rostami-Hodjegan, 2009, The AAPS Journal.

Prediction of the in vivo behaviour of modified release formulations of metoprolol from in vitro dissolution profiles using the ADAM model (Simcyp V8)

M. Jamei, S. Polak, G. Tucker, 2008 .

Misuse of the Well-Stirred Model of Hepatic Drug Clearance

M. Jamei, G. Tucker, A. Rostami-Hodjegan, 2007, Drug Metabolism and Disposition.

Safety, pharmacokinetics, pharmacodynamics, and bioavailability of GSK2018682, a sphingosine‐1‐phosphate receptor modulator, in healthy volunteers

Jiansong Yang, Jianfeng Xu, F. Gray, 2014, Clinical pharmacology in drug development.

Increased P-glycoprotein expression and decreased phenobarbital distribution in the brain of pentylenetetrazole-kindled rats

Xiao-dong Liu, Jiansong Yang, Hui-wen Yang, 2007, Neuropharmacology.

The effects of dose staggering on metabolic drug-drug interactions.

Amin Rostami-Hodjegan, Geoffrey T Tucker, Maria Kjellsson, 2003, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Physiologically based mechanistic modelling to predict complex drug-drug interactions involving simultaneous competitive and time-dependent enzyme inhibition by parent compound and its metabolite in both liver and gut - the effect of diltiazem on the time-course of exposure to triazolam.

Masoud Jamei, Amin Rostami-Hodjegan, Geoffrey T Tucker, 2010, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Implications of mechanism-based inhibition of CYP2D6 for the pharmacokinetics and toxicity of MDMA

Amir Heydari, Masoud Jamei, Amin Rostami-Hodjegan, 2006, Journal of psychopharmacology.

Prediction of intestinal first-pass drug metabolism.

Masoud Jamei, Amin Rostami-Hodjegan, Geoffrey T Tucker, 2007, Current drug metabolism.

Cytochrome P450 3A expression and activity in the human small intestine

Amin Rostami-Hodjegan, Geoffrey T Tucker, G. Tucker, 2004, Clinical pharmacology and therapeutics.

Discovery of novel 1,2,4-thiadiazole derivatives as potent, orally active agonists of sphingosine 1-phosphate receptor subtype 1 (S1P(1)).

J. D. Elliott, Wei Zhang, Xichen Lin, 2012, Journal of medicinal chemistry.

Simulation of Population Variability in Pharmacokinetics

Jiansong Yang, 2011 .

Cytochrome p450 turnover: regulation of synthesis and degradation, methods for determining rates, and implications for the prediction of drug interactions.

Masoud Jamei, Amin Rostami-Hodjegan, Geoffrey T Tucker, 2008, Current drug metabolism.

Physiologically-based Kinetic Modelling (PBK Modelling): Meeting the 3Rs Agenda

Ursula Gundert-Remy, Martin Spendiff, Alan Boobis, 2007, Alternatives to laboratory animals : ATLA.

Adjustment of the area under the concentration curve by terminal rate constant for bioequivalence assessment in a parallel‐group study of lamotrigine

A. Nicholls, Peiming Ma, Chao Chen, 2019, British journal of clinical pharmacology.

Model-based Evaluation of the Clinical and Microbiological Efficacy of Vancomycin: A Prospective Study of Chinese Adult In-house Patients.

X. Liang, H. Ren, Jing Zhang, 2018, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

A Mechanistic Framework for In Vitro–In Vivo Extrapolation of Liver Membrane Transporters: Prediction of Drug–Drug Interaction Between Rosuvastatin and Cyclosporine

M. Jamei, F. Bajot, A. Rostami-Hodjegan, 2013, Clinical Pharmacokinetics.

Towards a quantitative framework for the prediction of DDIs arising from cytochrome P450 induction.

M Jamei, M. Jamei, G. Tucker, 2009, Current drug metabolism.

The impact of experimental design on assessing mechanism-based inactivation of CYP2D6 by MDMA (Ecstasy)

Amir Heydari, Amin Rostami-Hodjegan, Karen Rowland-Yeo, 2006, Journal of psychopharmacology.

Effect of tamsulosin on the pharmacokinetics of dutasteride in Chinese male healthy volunteers

Huafang Li, Chunrong Wang, Jiansong Yang, 2015, Clinical pharmacology in drug development.

M. Jamei, G. Tucker, A. Rostami-Hodjegan, 2010, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.