C. Tannergren

发表

IMI – Oral biopharmaceutics tools project – Evaluation of bottom‐up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes

Amitava Mitra, Jian Lin, Mai Anh Nguyen, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

IMI – Oral biopharmaceutics tools project – Evaluation of bottom‐up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results

Amitava Mitra, Jian Lin, Mai Anh Nguyen, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

IMI – oral biopharmaceutics tools project – evaluation of bottom‐up PBPK prediction success part 1: Characterisation of the OrBiTo database of compounds

Xavier Pepin, Leon Aarons, Hans Lennernäs, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

In Silico Modeling of Gastrointestinal Drug Absorption: Predictive Performance of Three Physiologically Based Absorption Models.

Erik Sjögren, Christer Tannergren, Helena Thörn, 2016, Molecular pharmaceutics.

Increased understanding of intestinal drug permeability determined by the LOC-I-GUT approach using multislice computed tomography.

H. Lennernäs, H. Ahlström, C. Tannergren, 2009, Molecular pharmaceutics.

The effect of pancreatic and biliary depletion on the in vivo pharmacokinetics of digoxin in pigs.

H. Lennernäs, S. Pierzynowski, L. Evilevitch, 2006, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

St John's Wort Decreases the Bioavailability of R‐ and S‐verapamil Through Induction of the First‐pass Metabolism

H. Lennernäs, M. Hedeland, U. Bondesson, 2004, Clinical pharmacology and therapeutics.

The effect of ketoconazole on the in vivo intestinal permeability of fexofenadine using a regional perfusion technique.

H. Lennernäs, L. Knutson, C. Tannergren, 2003, British journal of clinical pharmacology.

Regional Intestinal Permeability in Dogs: Biopharmaceutical Aspects for Development of Oral Modified-Release Dosage Forms.

H. Lennernäs, B. Abrahamsson, E. Sjögren, 2016, Molecular pharmaceutics.

IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling strategies.

M. Jamei, L. Aarons, M. Bolger, 2020, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Multiple transport mechanisms involved in the intestinal absorption and first‐pass extraction of fexofenadine

H. Lennernäs, M. Hedeland, U. Bondesson, 2003, Clinical pharmacology and therapeutics.

Absorption/metabolism of sulforaphane and quercetin, and regulation of phase II enzymes, in human jejunum in vivo.

G. Williamson, B. Holst, P. Kroon, 2003, Drug metabolism and disposition: the biological fate of chemicals.

Preclinical Effect of Absorption Modifying Excipients on Rat Intestinal Transport of Model Compounds and the Mucosal Barrier Marker 51Cr-EDTA.

H. Lennernäs, P. Langguth, E. Sjögren, 2017, Molecular pharmaceutics.

Regional Intestinal Permeability of Three Model Drugs in Human.

H. Lennernäs, B. Abrahamsson, P. Hellström, 2016, Molecular pharmaceutics.

The BioGIT System: a Valuable In Vitro Tool to Assess the Impact of Dose and Formulation on Early Exposure to Low Solubility Drugs After Oral Administration

P. Augustijns, R. Holm, C. Reppas, 2018, The AAPS Journal.

In silico predictions of gastrointestinal drug absorption in pharmaceutical product development: application of the mechanistic absorption model GI-Sim.

Erik Sjögren, Hans Lennernäs, Bertil Abrahamsson, 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

In vivo methods for drug absorption - comparative physiologies, model selection, correlations with in vitro methods (IVIVC), and applications for formulation/API/excipient characterization including food effects.

Talia Flanagan, Clive G. Wilson, Mai Anh Nguyen, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Transport Characteristics of Fexofenadine in the Caco-2 Cell Model

H. Lennernäs, C. Tannergren, N. Petri, 2004, Pharmaceutical Research.

PBPK models for the prediction of in vivo performance of oral dosage forms.

Martin Bergstrand, Xavier Pepin, Erik Sjögren, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

The effects of three absorption‐modifying critical excipients on the in vivo intestinal absorption of six model compounds in rats and dogs

H. Lennernäs, P. Langguth, E. Sjögren, 2018, International journal of pharmaceutics.

Comprehensive study on regional human intestinal permeability and prediction of fraction absorbed of drugs using the Ussing chamber technique.

Christer Tannergren, A. Ungell, Anna-Lena Ungell, 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Evaluation of drug permeability calculation based on luminal disappearance and plasma appearance in the rat single-pass intestinal perfusion model.

H. Lennernäs, E. Sjögren, C. Tannergren, 2019, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Effect of absorption‐modifying excipients, hypotonicity, and enteric neural activity in an in vivo model for small intestinal transport

H. Lennernäs, E. Sjögren, C. Tannergren, 2018, International journal of pharmaceutics.

Biopharmaceutic Profiling of Salts to Improve Absorption of Poorly Soluble Basic Drugs.

Sara Carlert, L. Lindfors, Eva M. Karlsson, 2016, Journal of pharmaceutical sciences.

Delivery and Pharmaceutical Technology Biopharmaceutic Pro fi ling of Salts to Improve Absorption of Poorly Soluble Basic Drugs

Sara Carlert, L. Lindfors, Eva M. Karlsson, 2016 .

Physiologically Based Biopharmaceutics Modeling of Regional and Colon Absorption in Dogs

C. Tannergren, Emma Eckernäs, 2021, Molecular pharmaceutics.

Nanofibrous Scaffolds Support a 3D in vitro Permeability Model of the Human Intestinal Epithelium

L. White, A. Ghaemmaghami, C. Roberts, 2019, Front. Pharmacol..

The BioGIT System: a Valuable In Vitro Tool to Assess the Impact of Dose and Formulation on Early Exposure to Low Solubility Drugs After Oral Administration

P. Augustijns, R. Holm, C. Reppas, 2018, The AAPS Journal.

In Vitro Biopredictive Methods: A Workshop Summary Report.

Amitava Mitra, Sandra Suarez-Sharp, Erik Sjögren, 2020, Journal of pharmaceutical sciences.

Reply to "Comment on 'In Silico Modeling of Gastrointestinal Drug Absorption: Predictive Performance of Three Physiologically Based Absorption Models'".

Erik Sjögren, Christer Tannergren, Helena Thörn, 2017, Molecular pharmaceutics.

Evaluation of an in vitro faecal degradation method for early assessment of the impact of colonic degradation on colonic absorption in humans.

Bertil Abrahamsson, Christer Tannergren, B. Abrahamsson, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

The Ussing Chamber Assay to Study Drug Metabolism and Transport in the Human Intestine

C. Heidecke, S. Oswald, M. Keiser, 2017, Current protocols in pharmacology.

Compound mixtures in Caco-2 cell permeability screens as a means to increase screening capacity.

P. Langguth, K. Hoffmann, C. Tannergren, 2001, Die Pharmazie.

Toward an increased understanding of the barriers to colonic drug absorption in humans: implications for early controlled release candidate assessment.

Hans Lennernäs, Bertil Abrahamsson, Christer Tannergren, 2009, Molecular pharmaceutics.

Regional Intestinal Permeability in Rats: A Comparison of Methods.

H. Lennernäs, B. Abrahamsson, E. Sjögren, 2017, Molecular pharmaceutics.

In Vivo Mechanisms of Intestinal Drug Absorption from Aprepitant Nanoformulations.

H. Lennernäs, B. Abrahamsson, J. Westergren, 2017, Molecular pharmaceutics.

Atomistic Modeling of Drug Permeability

J. Westergren, L. Lindfors, C. Tannergren, 2021 .

Clive G. Wilson, A. Peer, H. Lennernäs, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Parameterization of Physiologically Based Biopharmaceutics Models: Workshop Summary Report

Megerle L. Scherholz, Cordula Stillhart, Sumit Arora, 2024, Molecular pharmaceutics.