T. Korjamo

发表

IMI – Oral biopharmaceutics tools project – Evaluation of bottom‐up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes

Amitava Mitra, Jian Lin, Mai Anh Nguyen, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

IMI – Oral biopharmaceutics tools project – Evaluation of bottom‐up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results

Amitava Mitra, Jian Lin, Mai Anh Nguyen, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Modelling of drug disposition kinetics in in vitro intestinal absorption cell models.

Aki T Heikkinen, J. Mönkkönen, T. Korjamo, 2010, Basic & clinical pharmacology & toxicology.

Predicting the effect of prandial stage and particle size on absorption of ODM-204.

A. Juppo, T. Korjamo, R. Schilderink, 2020, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Effects of experimental setup on the apparent concentration dependency of active efflux transport in in vitro cell permeation experiments.

J. Mönkkönen, T. Korjamo, A. Heikkinen, 2010, Molecular pharmaceutics.

IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling strategies.

M. Jamei, L. Aarons, M. Bolger, 2020, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Metabolic and Efflux Properties of Caco-2 Cells Stably Transfected with Nuclear Receptors

O. Pelkonen, P. Honkakoski, J. Mönkkönen, 2006, Pharmaceutical Research.

Metabolism of Oxycodone in Human Hepatocytes from Different Age Groups and Prediction of Hepatic Plasma Clearance

H. Kokki, V. Ranta, M. Turpeinen, 2012, Front. Pharmacol..

Metabolism and Mass Balance of the Novel Nonsteroidal Androgen Receptor Inhibitor Darolutamide in Humans

M. Kähkönen, M. Koskinen, T. Korjamo, 2021, Drug Metabolism and Disposition.

Use of comprehensive screening methods to detect selective human CAR activators.

T. Laitinen, P. Honkakoski, J. Uusitalo, 2011, Biochemical pharmacology.

Kinetics of Cellular Retention during Caco-2 Permeation Experiments: Role of Lysosomal Sequestration and Impact on Permeability Estimates

J. Mönkkönen, T. Korjamo, A. Heikkinen, 2009, Journal of Pharmacology and Experimental Therapeutics.

Synthesis and antimicrobial activity of the symmetric dimeric form of Temporin A based on 3-N,N-di(3-aminopropyl)amino propanoic acid as the branching unit.

R. Laatikainen, A. Närvänen, J. Ratilainen, 2001, Bioorganic & medicinal chemistry.

TRPA1: a transducer and amplifier of pain and inflammation.

A. Pertovaara, K. Lindstedt, T. Korjamo, 2014, Basic & clinical pharmacology & toxicology.

Effect of temporin A modifications on its cytotoxicity and antimicrobial activity

K. Lappalainen, A. Närvänen, A. Välimaa, 2005, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

Effects of selective serotonin reuptake inhibitors on timolol metabolism in human liver microsomes and cryo-preserved hepatocytes.

J. Hakkola, O. Pelkonen, M. Turpeinen, 2010, Basic & clinical pharmacology & toxicology.

Analysis of unstirred water layer in in vitro permeability experiments.

J. Mönkkönen, T. Korjamo, A. Heikkinen, 2009, Journal of pharmaceutical sciences.

Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories.

P. Artursson, R. Hayeshi, A. Ungell, 2008, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Effect of N-betainate and N-piperazine derivatives of chitosan on the paracellular transport of mannitol in Caco-2 cells.

J. Mönkkönen, Jukka Holappa, J. Savolainen, 2008, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity

S. Karlsson, T. Ikonen, M. Ramachandra, 2018, Molecular Cancer Therapeutics.

Drug–Drug Interaction Potential of Darolutamide: In Vitro and Clinical Studies

Michaela Bairlein, M. Koskinen, T. Korjamo, 2019, European Journal of Drug Metabolism and Pharmacokinetics.

First-in-human Phase 1 open label study of the BET inhibitor ODM-207 in patients with selected solid tumours

R. Plummer, A. Snapir, I. Braña, 2020, British Journal of Cancer.

Transient Receptor Potential Ankyrin 1 Ion Channel Contributes to Guarding Pain and Mechanical Hypersensitivity in a Rat Model of Postoperative Pain

A. Pertovaara, T. Korjamo, A. Koivisto, 2012, Anesthesiology.

Drug adsorption to plastic containers and retention of drugs in cultured cells under in vitro conditions.

J. Mönkkönen, S. Auriola, T. Korjamo, 2006, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Absorption, distribution, metabolism and excretion of darolutamide (a novel non-steroidal androgen receptor antagonist) in rats

M. Kähkönen, S. Sandmann, M. Koskinen, 2020, Xenobiotica; the fate of foreign compounds in biological systems.

Absorption properties and P-glycoprotein activity of modified Caco-2 cell lines.

M. Reinisalo, P. Honkakoski, J. Mönkkönen, 2005, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

From known knowns to known unknowns: predicting in vivo drug metabolites.

Hannu Raunio, Olavi Pelkonen, Miia Turpeinen, 2009, Bioanalysis.

The Asymmetry of the Unstirred Water Layer in Permeability Experiments

J. Mönkkönen, T. Korjamo, A. Heikkinen, 2008, Pharmaceutical Research.

Decrease in Intracellular Concentration Causes the Shift in Km Value of Efflux Pump Substrates

J. Mönkkönen, T. Korjamo, A. Heikkinen, 2007, Drug Metabolism and Disposition.

1-Sulfonyl-6-Piperazinyl-7-Azaindoles as potent and pseudo-selective 5-HT6 receptor antagonists.

U. Pesonen, P. Prusis, M. Nowak, 2016, Bioorganic & medicinal chemistry letters.

Determination of permeation resistance distribution in in vitro cell monolayer permeation experiments.

J. Mönkkönen, T. Korjamo, A. Heikkinen, 2010, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.