Han-Dan He

IMI – Oral biopharmaceutics tools project – Evaluation of bottom‐up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes

Amitava Mitra, Jian Lin, Mai Anh Nguyen, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

IMI – Oral biopharmaceutics tools project – Evaluation of bottom‐up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results

Amitava Mitra, Jian Lin, Mai Anh Nguyen, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

A Simplified PBPK Modeling Approach for Prediction of Pharmacokinetics of Four Primarily Renally Excreted and CYP3A Metabolized Compounds During Pregnancy

Tycho Heimbach, Binfeng Xia, T. Heimbach, 2013, The AAPS Journal.

Practical Anticipation of Human Efficacious Doses and Pharmacokinetics Using In Vitro and Preclinical In Vivo Data

Tycho Heimbach, T. Heimbach, Suresh B. Lakshminarayana, 2009, The AAPS Journal.

Applications of Quantitative Systems Pharmacology in Model‐Informed Drug Discovery: Perspective on Impact and Opportunities

Rhys D O Jones, Jason R. Chan, M. Spilker, 2019, CPT: pharmacometrics & systems pharmacology.

Ribociclib Drug-Drug Interactions - Clinical Evaluations and PBPK Modeling to Guide Drug Labeling.

T. Heimbach, A. Chakraborty, Hilmar Schiller, 2020, Clinical pharmacology and therapeutics.

Drug-drug interaction (DDI) assessments of ruxolitinib, a dual substrate of CYP3A4 and CYP2C9, using a verified physiologically based pharmacokinetic (PBPK) model to support regulatory submissions

T. Heimbach, Hilmar Schiller, K. Umehara, 2019, Drug metabolism and personalized therapy.

IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling strategies.

M. Jamei, L. Aarons, M. Bolger, 2020, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 4: prediction of plasma concentration-time profiles in human from in vivo preclinical data by using the Wajima approach.

Rhys D O Jones, Vikash K. Sinha, V. Fischer, 2011, Journal of pharmaceutical sciences.

The identification of indacaterol as an ultralong-acting inhaled beta2-adrenoceptor agonist.

J. Fozard, B. Faller, D. Wyss, 2010, Journal of medicinal chemistry.

Physiologically based pharmacokinetic modeling for assessing the clinical drug-drug interaction of alisporivir.

T. Heimbach, Imad Hanna, G. Sunkara, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.