D. Hirt

发表

A Physiologically-Based Pharmacokinetic Model to Predict Human Fetal Exposure for a Drug Metabolized by Several CYP450 Pathways

S. Urien, N. Bouazza, S. Blanche, 2017, Clinical Pharmacokinetics.

Physiologically-based pharmacokinetic modeling of renally excreted antiretroviral drugs in pregnant women.

S. Urien, N. Bouazza, S. Blanche, 2015, British journal of clinical pharmacology.

Retention of Plasmodium falciparum ring-infected erythrocytes in the slow, open microcirculation of the human spleen.

J. Correas, A. Sauvanet, A. Couvelard, 2008, Blood.

Prediction of drug clearance in children

S. Urien, N. Bouazza, J. Treluyer, 2015, Journal of clinical pharmacology.

Estimation of piperacillin clearance with different glomerular filtration rate formulas in critically ill children

S. Urien, S. Renolleau, T. Nguyen-Khoa, 2020, British journal of clinical pharmacology.

Piperacillin Population Pharmacokinetics and Dosing Regimen Optimization in Critically Ill Children with Normal and Augmented Renal Clearance

S. Urien, E. Bille, S. Renolleau, 2018, Clinical Pharmacokinetics.

Methodological Approaches to Evaluate Fetal Drug Exposure.

S. Urien, N. Bouazza, J. Treluyer, 2019, Current pharmaceutical design.

Influence of Body Weight on Achieving Indinavir Concentrations Within Its Therapeutic Window in HIV-Infected Thai Patients Receiving Indinavir Boosted With Ritonavir

S. Urien, T. Cressey, J. Treluyer, 2011, Therapeutic drug monitoring.

Evaluation of nevirapine dosing recommendations in HIV-infected children.

S. Urien, P. Frange, N. Bouazza, 2013, British journal of clinical pharmacology.

Population pharmacokinetics of atazanavir/ritonavir in HIV-1-infected children and adolescents.

S. Urien, C. Dollfus, S. Blanche, 2011, British journal of clinical pharmacology.

Effect of a Roux-en-Y Gastric Bypass on the Pharmacokinetics of Oral Morphine Using a Population Approach

J. Oppert, J. Bouillot, C. Poitou, 2014, Clinical Pharmacokinetics.

Sleeve Gastrectomy in Morbidly Obese HIV Patients: Focus on Anti-retroviral Treatment Absorption After Surgery

J. Oppert, L. Genser, J. Bouillot, 2018, Obesity Surgery.

Population Pharmacokinetics of Emtricitabine in HIV-1-Infected Adult Patients

S. Urien, N. Bouazza, J. Treluyer, 2014, Antimicrobial Agents and Chemotherapy.

Population Pharmacokinetics Study of Recommended Zidovudine Doses in HIV-1-Infected Children

S. Urien, P. Frange, N. Bouazza, 2013, Antimicrobial Agents and Chemotherapy.

Population Analysis of Weight-, Age-, and Sex-Related Differences in the Pharmacokinetics of Lopinavir in Children from Birth to 18 Years

C. Delaugerre, C. Rouzioux, S. Urien, 2006, Antimicrobial Agents and Chemotherapy.

Pharmacology and immuno-virologic efficacy of once-a-day HAART in African HIV-infected children: ANRS 12103 phase II trial.

P. Van de Perre, V. Foulongne, M. Segondy, 2011, Bulletin of the World Health Organization.

A novel pharmacokinetic approach to predict virologic failure in HIV-1-infected paediatric patients

S. Urien, P. Van de Perre, N. Bouazza, 2013, AIDS.

S. Urien, P. Perre, P. Msellati, 2009 .

Effect of Pregnancy on Unbound Raltegravir Concentrations in the ANRS 160 RalFe Trial

S. Urien, N. Bouazza, J. Warszawski, 2020, Antimicrobial Agents and Chemotherapy.

Prediction of human fetal pharmacokinetics using ex vivo human placenta perfusion studies and physiologically based models.

S. Urien, N. Bouazza, M. Lê, 2016, British journal of clinical pharmacology.

Population Pharmacokinetic Model to Optimize Cefotaxime Dosing Regimen in Critically Ill Children

S. Urien, S. Renolleau, J. Treluyer, 2018, Clinical Pharmacokinetics.

Development of a simple and rapid method to determine the unbound fraction of dolutegravir, raltegravir and darunavir in human plasma using ultrafiltration and LC-MS/MS.

N. Bouazza, J. Treluyer, Gabrielle Lui, 2021, Journal of pharmaceutical and biomedical analysis.

HPLC-MS/MS method for the simultaneous quantification of dolutegravir, elvitegravir, rilpivirine, darunavir, ritonavir, raltegravir and raltegravir-β-d-glucuronide in human plasma.

N. Bouazza, J. Treluyer, Gabrielle Lui, 2020, Journal of pharmaceutical and biomedical analysis.

Development and validation of a LC-MS/MS method for the quantification of tenofovir and emtricitabine in seminal plasma.

J. Wolf, E. Dulioust, J. Treluyer, 2016, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Population pharmacokinetics of meropenem in critically ill children with different renal functions

S. Urien, E. Bille, N. Bouazza, 2019, European Journal of Clinical Pharmacology.

slow, open microcirculation of the human spleen Retention of Plasmodium falciparum ring-infected erythrocytes in the

J. Correas, A. Sauvanet, A. Couvelard, 2013 .

Blood concentrations are better predictors of chioroquine poisoning severity than plasma concentrations: a prospective study with modeling of the concentration/effect relationships

B. Mégarbane, N. Deye, M. Debray, 2010, Clinical toxicology.

Simultaneous quantification of levofloxacin, pefloxacin, ciprofloxacin and moxifloxacin in microvolumes of human plasma using high-performance liquid chromatography with ultraviolet detection.

J. Treluyer, Gabrielle Lui, Yi Zheng, 2019, Biomedical chromatography : BMC.

Concentrations of Tenofovir and Emtricitabine in Breast Milk of HIV-1-Infected Women in Abidjan, Côte d'Ivoire, in the ANRS 12109 TEmAA Study, Step 2

F. Dabis, S. Urien, D. Ekouevi, 2010, Antimicrobial Agents and Chemotherapy.

Maternal and fetal zidovudine pharmacokinetics during pregnancy and labour: too high dose infused at labour?

S. Urien, N. Bouazza, J. Treluyer, 2014, British journal of clinical pharmacology.

High Exposure to Zidovudine During the First 2 Weeks of Life and Concentration—Toxicity Relationships

S. Urien, S. Blanche, H. Chappuy, 2013, Journal of acquired immune deficiency syndromes.

Evaluation of Zidovudine recommended doses in HIV-1 infected 1 children : a population pharmacokinetics study 2 3

S. Urien, N. Bouazza, J. Treluyer, 2013 .

Didanosine Population Pharmacokinetics in West African Human Immunodeficiency Virus-Infected Children Administered Once-Daily Tablets in Relation to Efficacy after One Year of Treatment

S. Urien, P. Van de Perre, C. Bardin, 2009, Antimicrobial Agents and Chemotherapy.

Modified renal function in pregnancy: impact on emtricitabine pharmacokinetics.

F. Dabis, S. Urien, N. Bouazza, 2014, British Journal of Clinical Pharmacology.

Plasma and Intracellular Tenofovir Pharmacokinetics in the Neonate (ANRS 12109 Trial, Step 2)

F. Dabis, S. Urien, D. Ekouevi, 2011, Antimicrobial Agents and Chemotherapy.

S. Urien, N. Bouazza, O. Launay, 2011, Antimicrobial Agents and Chemotherapy.

Population Pharmacokinetics of Tenofovir in HIV‐1‐Infected Pregnant Women and Their Neonates (ANRS 12109)

F. Dabis, S. Urien, G. Gray, 2009, Clinical pharmacology and therapeutics.

Are Prophylactic and Therapeutic Target Concentrations Different?: the Case of Lopinavir-Ritonavir or Lamivudine Administered to Infants for Prevention of Mother-to-Child HIV-1 Transmission during Breastfeeding

C. Kankasa, P. Van de Perre, N. Bouazza, 2016, Antimicrobial Agents and Chemotherapy.

Emtricitabine Seminal Plasma and Blood Plasma Population Pharmacokinetics in HIV-Infected Men in the EVARIST ANRS-EP 49 Study

C. Rouzioux, S. Urien, M. Suzan-Monti, 2015, Antimicrobial Agents and Chemotherapy.

Population Pharmacokinetics of Emtricitabine in Human Immunodeficiency Virus Type 1-Infected Pregnant Women and Their Neonates

F. Dabis, S. Urien, D. Ekouevi, 2008, Antimicrobial Agents and Chemotherapy.

Suboptimal cotrimoxazole prophylactic concentrations in HIV‐infected children according to the WHO guidelines

S. Blanche, V. Leroy, J. Treluyer, 2017, British journal of clinical pharmacology.

Population Pharmacokinetics of Emtricitabine in HIV-1 infected Pregnant Women and their neonates ( ANRS 12109 )

F. Dabis, S. Urien, D. Ekouevi, 2008 .

Developmental Pharmacokinetics of Lamivudine in 580 Pediatric Patients Ranging from Neonates to Adolescents

S. Urien, P. Frange, N. Bouazza, 2011, Antimicrobial Agents and Chemotherapy.

Evaluation of effect of impaired renal function on lamivudine pharmacokinetics.

S. Urien, N. Bouazza, J. Treluyer, 2014, British journal of clinical pharmacology.

Lopinavir-Ritonavir Impairs Adrenal Function in Infants.

M. Polak, D. Kariyawasam, J. Molès, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Concentration-response Model of Lopinavir/Ritonavir in HIV-1–infected Pediatric Patients

S. Urien, P. Frange, N. Bouazza, 2014, The Pediatric infectious disease journal.

An optimized ibuprofen dosing scheme for preterm neonates with patent ductus arteriosus, based on a population pharmacokinetic and pharmacodynamic study.

S. Urien, P. Schepens, B. Van Overmeire, 2008, British journal of clinical pharmacology.

Population Pharmacokinetics of Intravenous and Oral Acyclovir and Oral Valacyclovir in Pediatric Population To Optimize Dosing Regimens

N. Bouazza, J. Treluyer, Yi Zheng, 2020, Antimicrobial Agents and Chemotherapy.

S. Urien, S. Blanche, V. Jullien, 2006, Antimicrobial Agents and Chemotherapy.

Population Approach To Analyze the Pharmacokinetics of Free and Total Lopinavir in HIV-Infected Pregnant Women and Consequences for Dose Adjustment

R. Tubiana, S. Urien, L. Mandelbrot, 2015, Antimicrobial Agents and Chemotherapy.

S. Urien, P. Van de Perre, P. Msellati, 2009, Antimicrobial Agents and Chemotherapy.

Extended pre-exposure prophylaxis with lopinavir–ritonavir versus lamivudine to prevent HIV-1 transmission through breastfeeding up to 50 weeks in infants in Africa (ANRS 12174): a randomised controlled trial

P. Musoke, T. Gundu, C. Kankasa, 2016, The Lancet.

Population Pharmacokinetics of Abacavir in Pregnant Women

S. Urien, J. Treluyer, D. Hirt, 2014, Antimicrobial Agents and Chemotherapy.

S. Urien, N. Bouazza, S. Blanche, 2011, Antimicrobial Agents and Chemotherapy.

Pharmacokinetics and Virological Efficacy after Switch to Once-Daily Lopinavir-Ritonavir in Treatment-Experienced HIV-1-Infected Children

S. Urien, P. Frange, S. Blanche, 2011, Antimicrobial Agents and Chemotherapy.

Lopinavir/ritonavir population pharmacokinetics in neonates and infants.

S. Khoo, S. Anderson, S. Urien, 2011, British journal of clinical pharmacology.

S. Urien, P. Van de Perre, N. Bouazza, 2010, Antimicrobial Agents and Chemotherapy.

Determination of total and unbound concentrations of lopinavir in plasma using liquid chromatography-tandem mass spectrometry and ultrafiltration methods.

R. Tubiana, J. Warszawski, J. Treluyer, 2014, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Population Pharmacokinetic Modeling of Tenofovir in the Genital Tract of Male HIV-Infected Patients

C. Rouzioux, S. Urien, M. Suzan-Monti, 2016, Antimicrobial Agents and Chemotherapy.

Comparison of three galenic forms of lamivudine in young West African children living with Human Immunodeficiency Virus

S. Urien, N. Bouazza, A. Pruvost, 2021, Antiviral therapy.

Pharmacokinetic modelling of the placental transfer of nelfinavir and its M8 metabolite: a population study using 75 maternal-cord plasma samples.

S. Urien, L. Mandelbrot, H. Chappuy, 2007, British journal of clinical pharmacology.

Pharmacokinetics of Efavirenz at a High Dose of 25 Milligrams per Kilogram per Day in Children 2 to 3 Years Old

N. Bouazza, S. Blanche, V. Leroy, 2017, Antimicrobial Agents and Chemotherapy.

Lopinavir/ritonavir monotherapy as a nucleoside analogue-sparing strategy to prevent HIV-1 mother-to-child transmission: the ANRS 135 PRIMEVA phase 2/3 randomized trial.

R. Tubiana, C. Rouzioux, L. Mandelbrot, 2013, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

S. Urien, L. Mandelbrot, H. Chappuy, 2006, Antimicrobial Agents and Chemotherapy.

Population pharmacokinetics of intravenous and oral ciprofloxacin in children to optimize dosing regimens

N. Bouazza, S. Blanot, P. Léger, 2021, European Journal of Clinical Pharmacology.

Maternal Betamethasone for Prevention of Respiratory Distress Syndrome in Neonates: Population Pharmacokinetic and Pharmacodynamic Approach

Y. Ville, L. Mandelbrot, N. Bouazza, 2020, Clinical pharmacology and therapeutics.

Population pharmacokinetics of meropenem in critically ill children with different renal functions

S. Urien, E. Bille, N. Bouazza, 2019, European Journal of Clinical Pharmacology.

Determination of optimal cholecalciferol treatment in renal transplant recipients using a population pharmacokinetic approach

S. Urien, E. Thervet, J. Souberbielle, 2012, European Journal of Clinical Pharmacology.

Model of population pharmacokinetics of cidofovir in immunocompromised children with cytomegalovirus and adenovirus infection

P. Frange, B. Neven, N. Néant, 2018, The Journal of antimicrobial chemotherapy.

Beta-lactam exposure and safety in intermittent or continuous infusion in critically ill children: an observational monocenter study

E. Bille, S. Renolleau, J. Treluyer, 2022, European Journal of Pediatrics.

Very High Concentrations of Active Intracellular Phosphorylated Emtricitabine in Neonates (ANRS 12109 Trial, Step 2)

F. Dabis, S. Urien, G. Gray, 2011, Antimicrobial Agents and Chemotherapy.

Determination of optimal cholecalciferol treatment in renal transplant recipients using a population pharmacokinetic approach

S. Urien, E. Thervet, J. Souberbielle, 2013, European Journal of Clinical Pharmacology.

Sprague-Dawley rats display sex-linked differences in the pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA) and its metabolite 3,4-methylenedioxyamphetamine (MDA).

M. Debray, X. Declèves, F. Noble, 2009, Toxicology and applied pharmacology.

Simulations of Valproate Doses Based on an External Evaluation of Pediatric Population Pharmacokinetic Models

R. Nabbout, I. Desguerre, N. Bouazza, 2018, Journal of clinical pharmacology.

Population pharmacokinetics of 3,4-methylenedioxymethamphetamine and main metabolites in rats.

M. Debray, X. Declèves, F. Noble, 2010, Toxicological sciences : an official journal of the Society of Toxicology.

Challenges regarding analysis of unbound fraction of highly bound protein antiretroviral drugs in several biological matrices: lack of harmonisation and guidelines.

S. Urien, J. Treluyer, S. Illamola, 2015, Drug discovery today.

Dosing Recommendations for Lamotrigine in Children: Evaluation Based on Previous and New Population Pharmacokinetic Models

R. Nabbout, I. Desguerre, N. Bouazza, 2020, Journal of clinical pharmacology.

Population Pharmacokinetics of Tenofovir in HIV-1–Infected Pediatric Patients

S. Urien, P. Frange, N. Bouazza, 2011, Journal of acquired immune deficiency syndromes.

Population Pharmacokinetics of Intravenous Ganciclovir and Oral Valganciclovir in a Pediatric Population To Optimize Dosing Regimens

N. Bouazza, J. Treluyer, D. Hirt, 2020, Antimicrobial Agents and Chemotherapy.

Pharmacokinetic profile of acyclovir in a child receiving continuous kidney replacement therapy for acute liver failure

D. Hirt, M. Oualha, C. Heilbronner, 2023, Pediatric nephrology.

Population Pharmacokinetics of Nevirapine in HIV-1-Infected Pregnant Women and Their Neonates

F. Dabis, S. Urien, G. Gray, 2010, Antimicrobial Agents and Chemotherapy.

Effect of CYP2C19 polymorphism on nelfinavir to M8 biotransformation in HIV patients.

France Mentré, Xavier Duval, F. Mentré, 2008, British journal of clinical pharmacology.

Therapeutic Drug Monitoring of Antibiotics in Critically Ill Children: An Observational Study in a Pediatric Intensive Care Unit

E. Bille, S. Renolleau, F. Moulin, 2022, Therapeutic drug monitoring.

Population pharmacokinetics of cefazolin in critically ill children infected with methicillin-sensitive Staphylococcus aureus.

S. Urien, E. Bille, S. Renolleau, 2020, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

A meropenem pharmacokinetics model in patients with haematological malignancies.

S. Kernéis, D. Bouscary, R. Gauzit, 2020, The Journal of antimicrobial chemotherapy.

Free prednisolone pharmacokinetics predicted from total concentrations in patients with inflammatory – immunonologic conditions

S. Urien, L. Mouthon, N. Bouazza, 2020, Fundamental & clinical pharmacology.

Population Pharmacokinetics of Abacavir in Pregnant Women 1 2

S. Urien, J. Treluyer, D. Hirt, 2014 .

Cefepime population pharmacokinetics and dosing regimen optimization in critically ill children with different renal function.

S. Vimont, E. Bille, P. Léger, 2022, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Early Bayesian Dose Adjustment of Vancomycin Continuous Infusion in Children in a Randomized Controlled Trial

N. Bouazza, J. Treluyer, D. Hirt, 2019, Antimicrobial Agents and Chemotherapy.

Frequencies, Modalities, Doses and Duration of Computerized Prescriptions for Sedative, Analgesic, Anesthetic and Paralytic Drugs in Neonates Requiring Intensive Care: A Prospective Pharmacoepidemiologic Cohort Study in 30 French NICUs From 2014 to 2020

J. Gouyon, R. Carbajal, D. Hirt, 2022, Frontiers in pharmacology.

Predictive Performance of Population Pharmacokinetic Models of Levetiracetam in Children and Evaluation of Dosing Regimen

R. Nabbout, I. Desguerre, N. Bouazza, 2021, Journal of clinical pharmacology.

Efficacy and safety of subcutaneous administration of ceftazidime as a salvage therapy in geriatrics: a case report

J. Alvarez, A. Dinh, D. Hirt, 2019, Fundamental & clinical pharmacology.

Nevirapine Pharmacokinetics in Neonates Between 25 and 32 Weeks Gestational Age for the Prevention of Mother-to-Child Transmission of HIV

P. Jarreau, J. Treluyer, D. Hirt, 2021, The Pediatric infectious disease journal.