Zhi-wei Gao

发表

Preclinical pharmacokinetics of TPN729MA, a novel PDE5 inhibitor, and prediction of its human pharmacokinetics using a PBPK model

Xiaoyan Chen, D. Zhong, Yifan Zhang, 2015, Acta Pharmacologica Sinica.

Pharmacodynamic and pharmacokinetic effects of S086, a novel angiotensin receptor neprilysin inhibitor.

Xiaoyan Chen, Zhi-wei Gao, Guofeng Sun, 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

The Nonclinical Pharmacokinetics and Prediction of Human Pharmacokinetics of SPH3127, a Novel Direct Renin Inhibitor

Xiaoyan Chen, Zhi-wei Gao, Guangxin Xia, 2019, European Journal of Drug Metabolism and Pharmacokinetics.

A self-assembled nanodelivery system enhances the oral bioavailability of daidzein: in vitro characteristics and in vivo performance.

Fang Gao, Y. Huang, Yaping Li, 2011, Nanomedicine.

Role of CYP3A in isoniazid metabolism in vivo.

Jie Lu, Feng Li, Xiaochao Ma, 2014, Drug metabolism and pharmacokinetics.

Note Role of CYP 3 A in Isoniazid Metabolism In Vivo

C. Klaassen, Ke Liu, Zhi-wei Gao, 2014 .

Population Pharmacokinetic and Covariate Analysis of Apatinib, an Oral Tyrosine Kinase Inhibitor, in Healthy Volunteers and Patients with Solid Tumors

Xiaoyan Chen, D. Zhong, Xiao-jian Dai, 2016, Clinical Pharmacokinetics.

Development and validation of a sensitive LC-MS/MS assay for the simultaneous quantification of allitinib and its two metabolites in human plasma.

Xiaoyan Chen, D. Zhong, Zhi-wei Gao, 2013, Journal of pharmaceutical and biomedical analysis.

Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma

Jia Li, Yifan Zhang, An-hui Gao, 2021, Acta pharmacologica Sinica.

Poly(ADP-ribose)polymerase (PARP) inhibition and anticancer activity of simmiparib, a new inhibitor undergoing clinical trials.

Na Ye, Yi Chen, Z. Miao, 2017, Cancer letters.

The characteristics and mechanism of simvastatin loaded lipid nanoparticles to increase oral bioavailability in rats.

Fang Gao, Y. Huang, Yaping Li, 2010, International journal of pharmaceutics.

Effects of ketoconazole and rifampicin on the pharmacokinetics of GLS4, a novel anti-hepatitis B virus compound, in dogs

Xiaoyan Chen, D. Zhong, Zhi-wei Gao, 2013, Acta Pharmacologica Sinica.

Nanoemulsion improves the oral absorption of candesartan cilexetil in rats: Performance and mechanism.

Chunjie Zhao, Yan Huang, Jianan Shen, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia.

Hualiang Jiang, Yue Huang, Cai-Guang Yang, 2019, Cancer cell.

Metabolism and Pharmacokinetics of Novel Selective Vascular Endothelial Growth Factor Receptor-2 Inhibitor Apatinib in Humans

Xiaoyan Chen, D. Zhong, Xiao-jian Dai, 2013, Drug Metabolism and Disposition.

Small-Molecule Targeting of E3 Ligase Adaptor SPOP in Kidney Cancer.

Cheng Luo, Jin Ren, Ke Chen, 2016, Cancer cell.

Identification of methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) as an orally bioavailable, highly potent, PI3K alpha inhibitor for the treatment of advanced solid tumors.

Yi Chen, Jian Ding, Xiaoyan Chen, 2020, European journal of medicinal chemistry.

Metabolism and bioactivation of famitinib, a novel inhibitor of receptor tyrosine kinase, in cancer patients

Xiaoyan Chen, D. Zhong, Cen Xie, 2013, British journal of pharmacology.

Novel PARP1/2 inhibitor mefuparib hydrochloride elicits potent in vitro and in vivo anticancer activity, characteristic of high tissue distribution

M. Wang, Yi Chen, Z. Miao, 2016, Oncotarget.

Metabolism and Pharmacokinetics of Allitinib in Cancer Patients: The Roles of Cytochrome P450s and Epoxide Hydrolase in its Biotransformation

Xiaoyan Chen, D. Zhong, Cen Xie, 2014, Drug Metabolism and Disposition.

DMD056341 872..884

Xiaoyan Chen, D. Zhong, Cen Xie, 2014 .

Metabolism and Pharmacokinetics of Allitinib in Cancer Patients: The Roles of Cytochrome P450s and Epoxide Hydrolase in its Biotransformation s

Xiaoyan Chen, D. Zhong, Cen Xie, 2014 .

Metabolism and Pharmacokinetics of Novel Selective Vascular Endothelial Growth Factor Receptor-2 Inhibitor Apatinib in Humans s

Xiaoyan Chen, D. Zhong, Xiao-jian Dai, 2013 .