G. Allan

发表

Case studies addressing human pharmacokinetic uncertainty using a combination of pharmacokinetic simulation and alternative first in human paradigms

Alex Phipps, Maurice Dickins, Tanya L Hay, 2012, Xenobiotica; the fate of foreign compounds in biological systems.

Pre-clinical pharmacokinetics of UK-453,061, a novel non-nucleoside reverse transcriptase inhibitor (NNRTI), and use of in silico physiologically based prediction tools to predict the oral pharmacokinetics of UK-453,061 in man

Maurice Dickins, Iain Gardner, Hannah M. Jones, 2008 .

N-[(3S)-Pyrrolidin-3-yl]benzamides as novel dual serotonin and noradrenaline reuptake inhibitors: impact of small structural modifications on P-gp recognition and CNS penetration.

P. Fish, T. Ryckmans, S. Phillips, 2009, Bioorganic & medicinal chemistry letters.

Pharmacokinetic/pharmacodynamic assessment of the effects of E4031, cisapride, terfenadine and terodiline on monophasic action potential duration in dog

D. Walker, D. Leishman, A. Harrison, 2001, Xenobiotica; the fate of foreign compounds in biological systems.

Novel indazole non-nucleoside reverse transcriptase inhibitors using molecular hybridization based on crystallographic overlays.

Catherine Burt, Chris Phillips, T. Knöchel, 2009, Journal of medicinal chemistry.

Comparison of the Non‐Nucleoside Reverse Transcriptase Inhibitor Lersivirine with its Pyrazole and Imidazole Isomers

Chris Phillips, R. Corbau, C. Mowbray, 2011, Chemical biology & drug design.

Pharmacokinetics and metabolism of UK-383,367 in rats and dogs: A rationale for long-lived plasma radioactivity

S. Roffey, A. Nedderman, G. Allan, 2006, Xenobiotica; the fate of foreign compounds in biological systems.

Optimization of 5‐Aryloxyimidazole Non‐Nucleoside Reverse Transcriptase Inhibitors

R. Corbau, D. Hay, C. Mowbray, 2008, ChemMedChem.

Pre-clinical pharmacokinetics of UK-453,061, a novel non-nucleoside reverse transcriptase inhibitor (NNRTI), and use of in silico physiologically based prediction tools to predict the oral pharmacokinetics of UK-453,061 in man.

I. Gardner, I Gardner, T. Jenkins, 2008, Xenobiotica; the fate of foreign compounds in biological systems.

Determination of flutamide and hydroxyflutamide in dog plasma by a sensitive high performance liquid chromatography method utilizing mid-bore chromatography.

D. Sica, E. Cefali, G. Allan, 1994, Biomedical chromatography : BMC.

Potent and selective nonpeptidic inhibitors of procollagen C-proteinase.

Julian Blagg, P. Fish, R. Butt, 2007, Journal of medicinal chemistry.

Second generation N-(1,2-diphenylethyl)piperazines as dual serotonin and noradrenaline reuptake inhibitors: improving metabolic stability and reducing ion channel activity.

P. Fish, S. Phillips, G. Whitlock, 2010, Bioorganic & medicinal chemistry letters.

Case studies addressing human pharmacokinetic uncertainty using a combination of pharmacokinetic simulation and alternative first in human paradigms

Tanya L Hay, K. Beaumont, I. Gardner, 2012, Xenobiotica; the fate of foreign compounds in biological systems.