T. Poet

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Physiologically-based pharmacokinetic (PBPK) models in toxicity testing and risk assessment.

Kannan Krishnan, John C Lipscomb, S. Haddad, 2012, Advances in experimental medicine and biology.

Development of a physiologically based pharmacokinetic and pharmacodynamic model to determine dosimetry and cholinesterase inhibition for a binary mixture of chlorpyrifos and diazinon in the rat.

C Timchalk, T S Poet, T. Poet, 2008, Neurotoxicology.

In vitro rat hepatic and intestinal metabolism of the organophosphate pesticides chlorpyrifos and diazinon.

T. Poet, C. Timchalk, H. Wu, 2003, Toxicological sciences : an official journal of the Society of Toxicology.

Effects of Nicotine Exposure on In Vitro Metabolism of Chlorpyrifos in Male Sprague-Dawley Rats

T. Poet, C. Timchalk, S. Lee, 2008, Journal of toxicology and environmental health. Part A.

Monte Carlo analysis of the human chlorpyrifos-oxonase (PON1) polymorphism using a physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model.

C Timchalk, T S Poet, T. Poet, 2002, Toxicology letters.

Comparison of chlorpyrifos-oxon and paraoxon acetylcholinesterase inhibition dynamics: potential role of a peripheral binding site.

L. Sultatos, T. Poet, C. Timchalk, 2004, Toxicological sciences : an official journal of the Society of Toxicology.

Use of a probabilistic PBPK/PD model to calculate Data Derived Extrapolation Factors for chlorpyrifos

P. Price, M. Bartels, Jordan N. Smith, 2017, Regulatory toxicology and pharmacology : RTP.

In vitro uptake of methyl tert-butyl ether in male rat kidney: use of a two-compartment model to describe protein interactions.

S. Borghoff, T. Poet, 1997, Toxicology and applied pharmacology.

Safety assessment for ethanol-based topical antiseptic use by health care workers: Evaluation of developmental toxicity potential.

R. G. York, C. Kirman, A. Maier, 2015, Regulatory toxicology and pharmacology : RTP.

Physiologically based pharmacokinetic modeling of 1,4-Dioxane in rats, mice, and humans.

T. J. Weber, L. Sweeney, M. Gargas, 2008, Toxicological sciences : an official journal of the Society of Toxicology.

Comparative metabolism of carbon tetrachloride in rats, mice, and hamsters using gas uptake and PBPK modeling.

D. Grant, K. Weitz, D. M. Grant, 2000, Journal of toxicology and environmental health. Part A.

In Vitro Age-Dependent Enzymatic Metabolism of Chlorpyrifos and Chlorpyrifos-Oxon in Human Hepatic Microsomes and Chlorpyrifos-Oxon in Plasma

M. Bartels, Jordan N. Smith, T. Poet, 2011, Drug Metabolism and Disposition.

Effect of in vivo nicotine exposure on chlorpyrifos pharmacokinetics and pharmacodynamics in rats.

Jordan N. Smith, T. Poet, C. Timchalk, 2010, Chemico-biological interactions.

Age-dependent pharmacokinetic and pharmacodynamic response in preweanling rats following oral exposure to the organophosphorus insecticide chlorpyrifos.

T. Poet, C. Timchalk, A. Kousba, 2006, Toxicology.

Pharmacokinetic and pharmacodynamic interaction for a binary mixture of chlorpyrifos and diazinon in the rat.

M. Hinman, Melissa N. Hinman, T. Poet, 2005, Toxicology and applied pharmacology.

T. Poet, C. Timchalk, A. Kousba, 2007, Toxicological sciences : an official journal of the Society of Toxicology.

Stimulation of natural killer cell activity by murine retroviral infection and cocaine.

R. Watson, S. Wood, T. Poet, 1991, Toxicology letters.

Cocaine detection in hair: Effect of retroviral infection, age, morphine, and alcohol

T. Poet, 1991 .

Assessing dermal absorption.

T. Poet, 2000, Toxicological sciences : an official journal of the Society of Toxicology.

Extrapolation of plasma clearance to understand species differences in toxicokinetics of bisphenol A

S. Hays, T. Poet, 2018, Xenobiotica; the fate of foreign compounds in biological systems.

Assessment of the percutaneous absorption of trichloroethylene in rats and humans using MS/MS real-time breath analysis and physiologically based pharmacokinetic modeling.

H. Maibach, K. Weitz, H. Tanojo, 2000, Toxicological sciences : an official journal of the Society of Toxicology.

PBPK modeling of the percutaneous absorption of perchloroethylene from a soil matrix in rats and humans.

H. Maibach, K. Weitz, H. Tanojo, 2002, Toxicological sciences : an official journal of the Society of Toxicology.

Mode of action and pharmacokinetic studies of 2-butoxyethanol in the mouse with an emphasis on forestomach dosimetry.

K. Weitz, B. Thrall, T. Mast, 2003, Toxicological sciences : an official journal of the Society of Toxicology.

Development of an integrated microanalytical system for analysis of lead in saliva and linkage to a physiologically based pharmacokinetic model describing lead saliva secretion.

K. Weitz, T. Poet, C. Timchalk, 2001, AIHAJ : a journal for the science of occupational and environmental health and safety.

Proposed Occupational Exposure Limits for Non-Carcinogenic Hanford Waste Tank Vapor Chemicals

Torka S. Poet, Chuck Timchalk, T. Poet, 2006 .

Noninvasive Biomonitoring Approaches to Determine Dosimetry and Risk Following Acute Chemical Exposure: Analysis of Lead or Organophosphate Insecticide in Saliva

Yuehe Lin, J. Campbell, T. Poet, 2004, Journal of toxicology and environmental health. Part A.

Skin absorption and human risk assessment.

James N McDougal, T. Poet, Torka S Poet, 2002, Chemico-biological interactions.

Derivation of a human equivalent concentration for n-butanol using a physiologically based pharmacokinetic model for n-butyl acetate and metabolites n-butanol and n-butyric acid.

H J Clewell, H A Barton, R A Corley, 2005, Toxicological sciences : an official journal of the Society of Toxicology.

Comparative chlorpyrifos pharmacokinetics via multiple routes of exposure and vehicles of administration in the adult rat.

Dana B Barr, Charles Timchalk, D. Barr, 2009, Toxicology.

Comparative pharmacokinetics of chlorpyrifos versus its major metabolites following oral administration in the rat.

D. Barr, J. Campbell, T. Poet, 2010, Toxicology.

Deriving Biomonitoring Equivalents for selected E- and P-series glycol ethers for public health risk assessment.

S. Hays, N. Ball, T. Poet, 2016, International journal of hygiene and environmental health.

Physiologically based pharmacokinetic/pharmacodynamic model for the organophosphorus pesticide diazinon.

A A Kousba, C Timchalk, T S Poet, 2004, Neurotoxicology.

Characterization of the in vitro kinetic interaction of chlorpyrifos-oxon with rat salivary cholinesterase: a potential biomonitoring matrix.

A A Kousba, Charles Timchalk, T S Poet, 2003, Toxicology.

In vitro glutathione conjugation of methyl iodide in rat, rabbit, and human blood and tissues

R. Corley, T. Poet, Hong Wu, 2009, Inhalation toxicology.

In vitro measurements of metabolism for application in pharmacokinetic modeling.

John C Lipscomb, J. Lipscomb, T. Poet, 2008, Pharmacology & therapeutics.

Quantitative risk analysis for N-methyl pyrrolidone using physiologically based pharmacokinetic and benchmark dose modeling.

Christoph van Thriel, Michael Bader, C. Kirman, 2010, Toxicological sciences : an official journal of the Society of Toxicology.

Effect of murine retroviral infection on hair and serum levels of cocaine and morphine.

R. Watson, T. Poet, F. Martinez, 1992, Forensic science international.

TOXICOLOGICAL HIGHLIGHT Assessing Dermal Absorption

T. Poet, 2000 .

Chlorpyrifos PBPK/PD model for multiple routes of exposure

Charles Timchalk, M. Bartels, T. Poet, 2014, Xenobiotica; the fate of foreign compounds in biological systems.

Evaluation of thein VivoInteraction of Methyltert-Butyl Ether with α2u-Globulin in Male F-344 Rats☆

S. Borghoff, T. Poet, J. Prescott-Mathews, 1999 .

Determination of biokinetic interactions in chemical mixtures using real-time breath analysis and physiologically based pharmacokinetic modeling.

T. Poet, K. Thrall, 2000, Journal of toxicology and environmental health. Part A.

Utility of real time breath analysis and physiologically based pharmacokinetic modeling to determine the percutaneous absorption of methyl chloroform in rats and humans.

H. Maibach, K. Weitz, R. Wester, 2000, Toxicological sciences : an official journal of the Society of Toxicology.

Cocaine metabolite (benzoylecgonine) in hair and urine of drug users.

R. Watson, A. Estrada, T. Poet, 1993, Journal of analytical toxicology.

Methyl isobutyl ketone exposure-related increases in specific measures of α2u-globulin (α2u) nephropathy in male rats along with in vitro evidence of reversible protein binding.

S. Borghoff, S. Sarang, T. Poet, 2015, Toxicology.

Hydroquinone PBPK model refinement and application to dermal exposure.

P. Hinderliter, T. Poet, Paul M Hinderliter, 2010, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Using physiologically based pharmacokinetic modeling and benchmark dose methods to derive an occupational exposure limit for N-methylpyrrolidone.

C R Kirman, P M Schlosser, C. Kirman, 2016, Regulatory toxicology and pharmacology : RTP.

The effect of plasma lipids on the pharmacokinetics of chlorpyrifos and the impact on interpretation of blood biomonitoring data.

M Sue Marty, Charles Timchalk, M. Bartels, 2009, Toxicological sciences : an official journal of the Society of Toxicology.

Regional Brain Dosimetry for the Organophosphorus Insecticide Chlorpyrifos in the Preweanling Rat

T. Poet, C. Timchalk, Sookwang Lee, 2012 .

Derivation of human Biomonitoring Guidance Values for chlorpyrifos using a physiologically based pharmacokinetic and pharmacodynamic model of cholinesterase inhibition.

Manoj Aggarwal, Sean Hays, Scott M Arnold, 2015, Regulatory toxicology and pharmacology : RTP.

Development of a source-to-outcome model for dietary exposures to insecticide residues: an example using chlorpyrifos.

Paul S Price, Charles Timchalk, P. Price, 2011, Regulatory toxicology and pharmacology : RTP.

Application of a source-to-outcome model for the assessment of health impacts from dietary exposures to insecticide residues.

Paul S Price, Charles Timchalk, P. Price, 2011, Regulatory toxicology and pharmacology : RTP.

Metabolic rate constants for hydroquinone in F344 rat and human liver isolated hepatocytes: application to a PBPK model.

Richard A Corley, R. Corley, Hong Wu, 2004, Toxicological sciences : an official journal of the Society of Toxicology.

An age-dependent physiologically based pharmacokinetic/pharmacodynamic model for the organophosphorus insecticide chlorpyrifos in the preweanling rat.

Charles Timchalk, T. Poet, C. Timchalk, 2007, Toxicological sciences : an official journal of the Society of Toxicology.

Impact of Repeated Nicotine and Alcohol Coexposure on in Vitro and in Vivo Chlorpyrifos Dosimetry and Cholinesterase Inhibition

T. Poet, C. Timchalk, R. Gunawan, 2011, Journal of toxicology and environmental health. Part A.

A Real-Time In-vivo Method for Studying the Percutaneous Absorption of Volatile Chemicals

H. Maibach, K. Weitz, H. Tanojo, 2000, International journal of occupational and environmental health.

A human life-stage physiologically based pharmacokinetic and pharmacodynamic model for chlorpyrifos: development and validation.

Charles Timchalk, M. Bartels, P. Hinderliter, 2014, Regulatory toxicology and pharmacology : RTP.

Determination of age and gender differences in biochemical processes affecting the disposition of 2-butoxyethanol and its metabolites in mice and rats to improve PBPK modeling.

D. Grant, K. Weitz, R. Corley, 2005, Toxicology letters.

Application of a source-to-outcome model for the assessment of health impacts from dietary exposures to insecticide residues.

P. Price, M. Bartels, K. Schnelle, 2011, Regulatory toxicology and pharmacology : RTP.