E. Mulrooney

发表

Prediction of Phase I single-dose pharmacokinetics using recombinant cytochromes P450 and physiologically based modelling

F Kesisoglou, W. S. Denney, P. Lu, 2009, Xenobiotica; the fate of foreign compounds in biological systems.

Biosynthesis of UDP-N-acetyl-l-fucosamine, a Precursor to the Biosynthesis of Lipopolysaccharide in Pseudomonas aeruginosa Serotype O11*

D. McNally, J. Brisson, J. Lam, 2005, Journal of Biological Chemistry.

Identification of N-(1H-pyrazol-4-yl)carboxamide inhibitors of interleukin-1 receptor associated kinase 4: Bicyclic core modifications.

Duan Liu, M. Altman, Ruojing Yang, 2015, Bioorganic & medicinal chemistry letters.

Identification of Labile UDP‐Ketosugars in Helicobacter pylori, Campylobacter jejuni and Pseudomonas aeruginosa: Key Metabolites used to make Glycan Virulence Factors

D. McNally, J. Brisson, E. Vinogradov, 2006, Chembiochem : a European journal of chemical biology.

Applying the pro-drug approach to afford highly bioavailable antagonists of P2Y(14).

Yongxin Han, J. Gauthier, S. Kargman, 2011, Bioorganic & medicinal chemistry letters.

The identification of 4,7-disubstituted naphthoic acid derivatives as UDP-competitive antagonists of P2Y14.

J. Gauthier, S. Kargman, J. Mancini, 2011, Bioorganic & medicinal chemistry letters.

Discovery of 5-Amino-N-(1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide Inhibitors of IRAK4.

T. Fischmann, M. Altman, Ruojing Yang, 2015, ACS medicinal chemistry letters.

A Pharmacokinetic Modeling Approach to Predict the Contribution of Active Metabolites to Human Efficacious Dose

S. Hill, E. Mulrooney, Iain J Martin, 2016, Drug Metabolism and Disposition.

lfnA from Pseudomonas aeruginosa O12 and wbuX from Escherichia coli O145 Encode Membrane-Associated Proteins and Are Required for Expression of 2,6-Dideoxy-2-Acetamidino-l-Galactose in Lipopolysaccharide O Antigen

E. Vinogradov, J. Lam, K. Mead, 2007, Journal of bacteriology.

Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation.

Duan Liu, T. Fischmann, M. Altman, 2017, Bioorganic & medicinal chemistry letters.

A Pharmacokinetic Modeling Approach to Predict the Contribution of Active Metabolites to Human Efficacious Dose

S. Hill, E. Mulrooney, Iain J Martin, 2016, Drug Metabolism and Disposition.

Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation.

Duan Liu, T. Fischmann, M. Altman, 2017, Bioorganic & medicinal chemistry letters.

Identification of N-(1H-pyrazol-4-yl)carboxamide inhibitors of interleukin-1 receptor associated kinase 4: Bicyclic core modifications.

Duan Liu, M. Altman, Ruojing Yang, 2015, Bioorganic & medicinal chemistry letters.