H. Kato

发表

Structure-tissue distribution relationship based on physiological pharmacokinetics for NY-198, a new antimicrobial agent, and the related pyridonecarboxylic acids.

T. Terasaki, A. Tsuji, E. Okezaki, 1988, Drug metabolism and disposition: the biological fate of chemicals.

Physiological pharmacokinetics of a new muscle-relaxant, inaperisone, combined with its pharmacological effect on blood flow rate.

T. Terasaki, A. Tsuji, O. Nagata, 1990, Drug Metabolism And Disposition.

Entry of the new quinolone antibacterial agents of ofloxacin and NY-198 into the central nervous system in rats.

A. Tsuji, E. Okezaki, O. Nagata, 1988, Journal of pharmacobio-dynamics.

Study on zwitter-ionization of drugs. II. Synthesis and pharmacological activity of some N-[3-(5H-dibenzo[a, d]cyclohepten-5-ylidene) propyl]-N-methylamino- and N-[3-(6H-dibenz[b, e]oxepin-11-ylidene) propyl]-N-methylamino-alkanoic acid derivatives and related compounds.

T. Ohashi, H. Kato, H. Sawanishi, 1993, Chemical & pharmaceutical bulletin.

Efflux transport of a new quinolone antibacterial agent, HSR-903, across the blood-brain barrier.

I. Tamai, A. Tsuji, O. Nagata, 1999, The Journal of pharmacology and experimental therapeutics.

The house musk shrew (Suncus murinus): a unique animal with extremely low level of expression of mRNAs for CYP3A and flavin-containing monooxygenase.

T. Mushiroda, T. Kamataki, T. Yokoi, 2000, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.

Binding and functional characterization of alpha1-adrenoceptor subtypes in the rat prostate.

Y. Watanabe, O. Nagata, H. Kato, 1999, European journal of pharmacology.

Comparison of the efficacy of tacrolimus and cyclosporine A in a murine model of dinitrofluorobenzene-induced atopic dermatitis.

H. Kato, Hiroyuki Tanaka, H. Yamashita, 2010, European journal of pharmacology.

The suncus (Suncus murinus) shows poor metabolic phenotype for trimethylamine N-oxygenation.

T. Mushiroda, T. Kamataki, T. Yokoi, 2000, Toxicology and applied pharmacology.

A high-level expression of CYP2A in the lung of the suncus (Suncus murinus) and its role in the activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

T. Mushiroda, T. Kamataki, O. Nagata, 2000, Biochemical and biophysical research communications.

Synthesis and histamine H2-antagonist activity of 4-quinazolinone derivatives.

H. Kato, Y. Ito, T. Yoshida, 1988, Chemical & pharmaceutical bulletin.

Amphoteric drugs. I. Synthesis and antiallergic activity of [4-(diphenylmethoxy)piperidino]-, [4-(diphenylmethyl)piperazinyl]- and [4-(diphenylmethylene)piperidino]alkanoic acid derivatives.

T. Ohashi, H. Kato, H. Sawanishi, 1994, Chemical & pharmaceutical bulletin.

Uncatalysed (thermal) and Lewis acid-promoted asymmetric hetero-Diels–Alder reaction of 1-thiabuta-1,3-dienes (thiochalcones) with di-(–)-menthyl fumarate. Configuration determination by X-ray crystallographic analysis of (2S,3R,4R)-(+)-2,3-bis[(–)-menthoxycarbonyl]-4,6-diphenyl-3,4-dihydro-2H-thiop

Takao Saito, Kimiko Kobayashi, H. Kato, 1996 .

Synthesis, gastrointestinal prokinetic activity and structure-activity relationships of novel N-[[2-(dialkylamino)ethoxy]benzyl]benzamide derivatives.

H. Kato, S. Yasuda, Y. Ito, 1992, Chemical & pharmaceutical bulletin.

Heteroatom-facilitated lithiations of N-methyl-N-(trimethylsilyl)methyl-benzylamine and benzyl (trimethylsilyl)methyl ether with butyllithium

H. Kato, Seiko Mitsui, Yoshiriro Sato, 1993 .

Lithiation of (dialkylaminomethyl)trimethylsilanes

H. Kato, Yoshiro. Sato, S. Inoue, 1991 .

Synthesis and thromboxane A2 antagonistic activity of [[1-aryl(or benzyl)-1-(benzenesulfonamido)methyl]phenyl]alkanoic acid derivatives.

K. Kato, S. Sakurai, T. Ohashi, 1996, Chemical & pharmaceutical bulletin.

Studies on antispasmodics. V. Synthesis and anticholinergic activity of N-alkyl 1- and 2-diarylmethylene-indolizidinium bromides.

H. Kato, M. Hanaoka, S. Kubo, 1980, Chemical & pharmaceutical bulletin.

Studies on quinolone antibacterials. V. Synthesis and antibacterial activity of chiral 5-amino-7-(4-substituted-3-amino-1-pyrrolidinyl)-6- fluoro-1,4-dihydro-8-methyl-4-oxoquinoline-3-carboxylic acids and derivatives.

Y. Itoh, Y. Takahashi, H. Kato, 1996, Chemical & pharmaceutical bulletin.

Studies on quinolone antibacterials. IV. Structure-activity relationships of antibacterial activity and side effects for 5- or 8-substituted and 5,8-disubstituted-7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-1, 4-dihydro-4-oxoquinoline-3-carboxylic acids.

Y. Itoh, Y. Takahashi, H. Kato, 1996, Chemical & pharmaceutical bulletin.

Studies on macrolide antibiotics I. Synthesis and antibacterial activity of erythromycin A 9-O-substituted oxime ether derivatives against Mycobacterium avium complex.

Y. Takahashi, H. Kato, T. Yoshida, 2001, Chemical & pharmaceutical bulletin.

1H-Imidazo[4,5-c]quinoline derivatives as novel potent TNF-alpha suppressors: synthesis and structure-activity relationship of 1-, 2-and 4-substituted 1H-imidazo[4,5-c]quinolines or 1H-imidazo[4,5-c]pyridines.

Hitomi Dose, H. Kato, M. Takeshita, 2003, Bioorganic & medicinal chemistry.

Controlled Synthesis of C/D-Ring Components of Phycobilin Derivatives Bearing a Photoreactive Group at D-Ring

K. Jayasundera, H. Kinoshita, H. Kato, 1998 .

Metabolic fate of HY-770 (IV) : Disposition of the Metabolites and, Species Differences and Mechanism of Metabolism in rats, dogs, rabbits and human

O. Nagata, H. Kato, N. Inomata, 1992 .

Metabolic fate of HY-770 (III) Metabolism in rats

O. Nagata, H. Kato, E. Takahara, 1989 .

Inhibitory effects of quinolone antibacterial agents on gamma-aminobutyric acid binding to receptor sites in rat brain membranes

I. Tamai, A. Tsuji, H. Kato, 1988, Antimicrobial Agents and Chemotherapy.

Laxative and anti-diarrheal activity of polycarbophil in mice and rats.

H. Kato, Takaharu Saito, Y. Iwanaga, 2002, Japanese journal of pharmacology.

Serum protein binding of lomefloxacin, a new antimicrobial agent, and its related quinolones.

T. Terasaki, A. Tsuji, E. Okezaki, 1989, Journal of pharmaceutical sciences.

Amphoteric drugs. 3. Synthesis and antiallergic activity of 3-[(5,11-dihydro[1]benzoxepino[4,3-b]pyridin-11- ylidene)piperidino]propionic acid derivatives and related compounds.

T. Ohashi, H. Kato, S. Yasuda, 1995, Journal of medicinal chemistry.

Simultaneous determination of a new gastrointestinal prokinetic agent (HSR-803) and its metabolites in human serum and urine by high-performance liquid chromatography using automated column-switching.

T. Takagi, O. Nagata, H. Kato, 1992, Journal of chromatography.

Accumulation of the 1-methyl-4-phenylpyridinium ion in suncus (Suncus murinus) brain: implication for flavin-containing monooxygenase activity in brain microvessels.

T. Mushiroda, T. Kamataki, T. Yokoi, 2001, Chemical research in toxicology.

Studies on antiallergic agents. II. Quantitative structure-activity relationships of novel 6-substituted N-(1H-tetrazol-5-yl)-2-pyrazinecarboxamides.

T. Fujita, H. Kato, N. Iwasaki, 1990, Chemical & pharmaceutical bulletin.

Studies on antiallergic agents. I. Synthesis and antiallergic activity of novel pyrazine derivatives.

T. Ohashi, H. Kato, N. Iwasaki, 1990, Chemical & pharmaceutical bulletin.

Pharmacological studies on antispasmodics. IV

M. Yamazaki, H. Kato, I. Matsubara, 1981 .

Studies on antispasmodics. I. Synthesis and anticholinergic activity of 1-, 2-, and 3-diarylmethylenequinolizidine quaternary ammonium salts.

H. Kato, I. Matsubara, S. Kubo, 1979, Chemical and pharmaceutical bulletin.

STUDIES ON ANTISPASMODICS. I. SYNTHESIS AND ANTICHOLINERGIC ACTIVITY OF 1-, 2-, AND 3-DIARYLMETHYLENEQUINOLIZIDINE QUATERNARY AMMONIUM SALTS

H. Kato, I. Matsubara, S. Kubo, 1979 .

Novel phenoxyalkylamine derivatives. VII. Synthesis and pharmacological activities of 2-alkoxy-5-[(phenoxyalkylamino)alkyl]benzenesulfonamide derivatives.

S. Sakurai, H. Kato, S. Yasuda, 1992, Chemical & pharmaceutical bulletin.

Thermal and Lewis acid-promoted novel asymmetric hetero Diels–Alder reactions of a 1-thiabuta-1,3-diene system (thiochalcones) with (–)-dimenthyl fumarate

Takao Saito, H. Kato, S. Hayashibe, 1991 .

Thermal and Lewis Acid Promoted Novel Asymmetric Hetero Diels‐Alder Reactions of a 1‐Thiabuta‐1,3‐diene System (Thiochalcones) with (‐)‐ Dimenthyl Fumarate.

Takao Saito, H. Kato, S. Hayashibe, 1991 .

Transport mechanism of an H1-antagonist at the blood-brain barrier: transport mechanism of mepyramine using the carotid injection technique.

T. Terasaki, A. Tsuji, O. Nagata, 1994, Biological and Pharmaceutical Bulletin.

Carrier-Mediated Transport of H1-Antagonist at the Blood-Brain Barrier: A Common Transport System of H1-Antagonists and Lipophilic Basic Drugs

T. Terasaki, A. Tsuji, Yasuo Ito, 1994, Pharmaceutical Research.

Carrier-Mediated Transport of H1-Antagonist at the Blood–Brain Barrier: Mepyramine Uptake into Bovine Brain Capillary Endothelial Cells in Primary Monolayer Cultures

T. Terasaki, A. Tsuji, Yasuo Ito, 1994, Pharmaceutical Research.

Carrier-mediated lung distribution of HSR-903, a new quinolone antibacterial agent.

Y. Sai, I. Tamai, A. Tsuji, 1999, The Journal of pharmacology and experimental therapeutics.

Racemization kinetics of meluadrine tartrate in aqueous solution.

A. Tsuji, O. Nagata, H. Kato, 2001, Chemical & pharmaceutical bulletin.

Hepatobiliary transport kinetics of HSR-903, a new quinolone antibacterial agent.

Y. Sugiyama, Y. Sai, I. Tamai, 1998, Drug metabolism and disposition: the biological fate of chemicals.

Synthesis and dual antagonistic activity against thromboxane A2 and leukotriene D4 of [4-[1-(benzenesulfonamido)alkyl]phenyl]alkanoic acid derivatives.

K. Kato, S. Sakurai, T. Ohashi, 1997, Chemical & pharmaceutical bulletin.

Synthesis and gastrointestinal prokinetic activity of novel benzamide derivatives with amphoteric side chains.

T. Saito, H. Kato, M. Hanaoka, 2001, Chemical & pharmaceutical bulletin.

Studies on the relationship between physico-chemical properties and crystalline forms of tulobuterol hydrochloride. I. Polymorphism of tulobuterol hydrochloride.

H. Kato, M. Saito, M. Yamazaki, 1982 .

Polymorphism of α-[(tert-Butylamino) methyl]-2-chloro-4-hydroxybenzyl Alcohol Hydrochloride (HOKU-81)

Yasuo Ito, H. Kato, M. Saito, 1983 .

Derive de l'acide 5-amino-8-methyl-7-pyrrolidinylquinoline-3-carboxylique

Yasuo Ito, H. Kato, N. Kado, 1994 .

[Synthesis and bronchodilating activity of o-chloro-alpha-(tert-butylaminomethyl)-benzylalcohol hydrochloride (C-78) and related compounds (author's transl)].

H. Kato, S. Kubo, E. Koshinaka, 1978, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

[Development of transdermal formulation of tulobuterol for the treatment of bronchial asthma].

O. Nagata, H. Kato, Y. Nakano, 2002, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

Development of Transdermal Formulation of Tulobuterol for the Treatment of Bronchial Asthma

O. Nagata, H. Kato, Y. Nakano, 2002 .

SYNTHESIS AND BRONCHODILATING ACTIVITY OF O-CHLORO-α-(TERT-BUTYLAMINOMETHYL)-BENZYLALCOHOL HYDROCHLORIDE (C-78) AND RELATED COMPOUNDS

H. Kato, S. Kubo, E. Koshinaka, 1979 .

Pharmacological studies of 1-(2-chloro-4-hydroxyphenyl)-2-t-butylaminoethanol (HOKU-81), a new bronchodilator. 1st Communication: Bronchodilator and cardiovascular actions.

Y. Kaśe, H. Kato, S. Kasamatsu, 1980, Arzneimittel-Forschung.