P. Hsyu

发表

Application of Physiologically Based Pharmacokinetic Modeling to the Understanding of Bosutinib Pharmacokinetics: Prediction of Drug–Drug and Drug–Disease Interactions

S. Yamazaki, C. Loi, Chiho Ono, 2017, Drug Metabolism and Disposition.

Effect of aprepitant, a moderate CYP3A4 inhibitor, on bosutinib exposure in healthy subjects

Kyle T. Matschke, P. Hsyu, D. Pignataro, 2016, European Journal of Clinical Pharmacology.

The Application of Accelerator Mass Spectrometry to Absolute Bioavailability Studies in Humans: Simultaneous Administration of an Intravenous Microdose of 14C‐Nelfinavir Mesylate Solution and Oral Nelfinavir to Healthy Volunteers

Nenad Sarapa, R. C. Garner, N. Sarapa, 2005, Journal of clinical pharmacology.

Effect of bosutinib on the absorption of dabigatran etexilate mesylate, a P-glycoprotein substrate, in healthy subjects

Kyle T. Matschke, P. Hsyu, D. Pignataro, 2016, European Journal of Clinical Pharmacology.

Clinical Evaluation of the Nelfinavir‐Rifabutin Interaction in Patients with Tuberculosis and Human Immunodeficiency Virus Infection

Z. Zhao, A. Vernon, W. Burman, 2007, Pharmacotherapy.

Renal Transport of Drugs: An Overview of Methodology with Application to Cimetidine

K. Giacomini, P. Hsyu, L. Gisclon, 1988, Pharmaceutical Research.

Absolute Bioavailability of Bosutinib in Healthy Subjects From an Open‐Label, Randomized, 2‐Period Crossover Study

Kyle T. Matschke, P. Hsyu, D. Pignataro, 2018, Clinical pharmacology in drug development.

Pharmacokinetics of lamivudine in human immunodeficiency virus-infected patients with renal dysfunction

J. Bartlett, A. Heald, P. Hsyu, 1996, Antimicrobial agents and chemotherapy.

Pharmacokinetic–pharmacodynamic relationship of bosutinib in patients with chronic phase chronic myeloid leukemia

D. Mould, R. Upton, P. Hsyu, 2013, Cancer Chemotherapy and Pharmacology.

Clinical Pharmacokinetics and Pharmacodynamics of Bosutinib

P. Hsyu, R. Abbas, 2016, Clinical Pharmacokinetics.

Comparison of the Pharmacokinetics of an Ondansetron Solution (8 mg) When Administered Intravenously, Orally, to the Colon, and to the Rectum

W. H. Barr, T. L. Lloyd, R. Shamburek, 2004, Pharmaceutical Research.

Pharmacokinetics and cyclooxygenase inhibition of itazigrel in normal volunteers after single oral doses.

P. Hsyu, J. Luderer, M. Koets, 1994, Journal of pharmaceutical sciences.

Phase II, Randomized, Double-Blind, Placebo-Controlled Studies of Ruprintrivir Nasal Spray 2-Percent Suspension for Prevention and Treatment of Experimentally Induced Rhinovirus Colds in Healthy Volunteers

M. Gersten, F. Hayden, R. Turner, 2003, Antimicrobial Agents and Chemotherapy.

High performance liquid chromatographic determination of the enantiomers of beta-adrenoceptor blocking agents in biological fluids. I: Studies with pindolol.

K. Giacomini, P. Hsyu, 1986, Journal of pharmaceutical sciences.

Lack of Effect of Cimetidine on the Pharmacokinetics of Sustained‐Release Bupropion

R. Kustra, P. Hsyu, B. Corrigan, 1999, Journal of clinical pharmacology.

Pharmacokinetics of Bupropion and its Metabolites in Cigarette Smokers versus Nonsmokers

J. A. Johnston, J. Ascher, J. Dunn, 1997, Journal of clinical pharmacology.

Studies of the Interaction of Betacyclodextrin with Ampicillin, Methicillin and Phenytoin

C. Rhodes, P. Hsyu, R. Hegde, 1984 .

Renal Disposition and Drug Interaction Screening of (–)-2′-deoxy-3′-thiacytidine (3TC) in the Isolated Perfused Rat Kidney

P. Statkevich, P. Hsyu, K. Sweeney, 1995, Pharmaceutical Research.

Automated high-performance liquid chromatographic analysis of (-)-2'-deoxy-3'-thiacytidine in biological fluids using the automated sequential trace enrichment of dialysate systems.

P. Hsyu, T. Lloyd, 1994, Journal of chromatography. B, Biomedical applications.

Pharmacokinetic Interactions between Nelfinavir and 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors Atorvastatin and Simvastatin

P. Hsyu, Ronald H. Lewis, B. Kerr, 2001, Antimicrobial Agents and Chemotherapy.

Pharmacokinetics of Nelfinavir in Subjects With Hepatic Impairment

B. Damle, P. Hsyu, M. Becker, 2006, Journal of clinical pharmacology.

Stereoselective renal clearance of pindolol in humans.

K. Giacomini, P. Hsyu, 1985, The Journal of clinical investigation.

Interim report for a phase II, multi-centre, dose-escalating study of LB80380/ANA380 in hepatitis B patients with lamivudine-resistant YMDD mutant HBV

M. Yuen, S. Yoon, H. Chung, 2005 .

Pharmacokinetic interaction of nelfinavir and methadone in intravenous drug users

P. Hsyu, B. Kerr, J. Lillibridge, 2006, Biopharmaceutics & drug disposition.

Interactions of organic anions with the organic cation transporter in renal BBMV.

K. Giacomini, P. Hsyu, L. Gisclon, 1988, The American journal of physiology.

Mechanism of Intestinal Absorption of Ranitidine and Ondansetron: Transport Across Caco-2 Cell Monolayers

Liang-Shang Gan, D. Thakker, L. Gan, 1993, Pharmaceutical Research.

The pH gradient-dependent transport of organic cations in the renal brush border membrane. Studies with acridine orange.

K. Giacomini, P. Hsyu, 1987, The Journal of biological chemistry.

Phase I Study of Bosutinib, a Src/Abl Tyrosine Kinase Inhibitor, Administered to Patients with Advanced Solid Tumors

M. Borad, A. Daud, W. Messersmith, 2011, Clinical Cancer Research.

Safety profile and pharmacokinetic analyses of the anti-CTLA4 antibody tremelimumab administered as a one hour infusion

A. Abernethy, A. Ribas, R. Gonzalez, 2012, Journal of Translational Medicine.

USE OF CACO-2 CELLS AS AN IN VITRO INTESTINAL ABSORPTION AND METABOLISM MODEL

D. Thakker, L. Gan, P. Hsyu, 1994 .

Pharmacokinetic interactions between arbaprostil and aspirin in humans.

R. H. Pullen, J. W. Cox, P. Hsyu, 1989, Biopharmaceutics & drug disposition.

Pharmacokinetics and Safety of an Antirhinoviral Agent, Ruprintrivir, in Healthy Volunteers

M. Gersten, C. Penning, Y. Pithavala, 2002, Antimicrobial Agents and Chemotherapy.

Intracellular and Plasma Pharmacokinetics of Nelfinavir and M8 in HIV-Infected Patients: Relationship with P-Glycoprotein Expression

D. Cornforth, M. Johnson, S. Khoo, 2004, Antiviral therapy.

Essential tyrosine residues in transport of organic cations in renal BBMV.

K. Giacomini, P. Hsyu, 1987, The American journal of physiology.

Pharmacokinetics of Amiloride after Inhalation and Oral Administration in Adolescents and Adults with Cystic Fibrosis

M. Knowles, R. Boucher, G. Dukes, 1997, Pharmacotherapy.

Phase I dose escalation trial of tremelimumab plus sunitinib in patients (pts) with metastatic renal cell carcinoma (mRCC).

B. Rini, D. Healey, M. Gordon, 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Interactions of quinidine and quinine and (+)- and (-)-pindolol with the organic cation/proton antiporter in renal brush border membrane vesicles.

K. Giacomini, P. Hsyu, R. J. Ott, 1991, Biochemical pharmacology.

The effect of pindolol on the transport of L-lysine in renal brush border membrane vesicles.

K. Giacomini, P. Hsyu, F. M. Wong, 1988, Drug Metabolism And Disposition.

Population pharmacokinetic and pharmacodynamic analysis of bosutinib.

D. Mould, P. Hsyu, R. Abbas, 2014, Drug metabolism and pharmacokinetics.

Oral Ondansetron Pharmacokinetics: The Effect of Chemotherapy

A. Huang, P. Hsyu, J. Pritchard, 1994, Journal of clinical pharmacology.

Relationship between pharmacokinetics and safety of tremelimumab in patients with melanoma.

P. Hsyu, C. Bulanhagui, D. Wang, 2016, Journal of Clinical Oncology.