D. Bedwell

发表

The Impact of the Hepatocyte-to-Plasma pH Gradient on the Prediction of Hepatic Clearance and Drug-Drug Interactions for CYP2D6 Substrates

M. Mohutsky, D. Bedwell, K. Ruterbories, 2016, Drug Metabolism and Disposition.

Novel bicyclo[3.1.0]hexane analogs as antagonists of metabotropic glutamate 2/3 receptors for the treatment of depression.

J. F. Soriano, P. Ornstein, M. Blanco, 2016, Bioorganic & medicinal chemistry letters.

Hepatic Organic Anion Transporting Polypeptide–Mediated Clearance in the Beagle Dog: Assessing In Vitro–In Vivo Relationships and Applying Cross-Species Empirical Scaling Factors to Improve Prediction of Human Clearance

K. Hillgren, A. Galetin, J. Houston, 2018, Drug Metabolism and Disposition.

Metabotropic Glutamate Receptor

J. F. Soriano, P. Ornstein, S. Atwell, 2016 .

The Impact of the Hepatocyte-to-Plasma pH Gradient on the Prediction of Hepatic Clearance and Drug-Drug Interactions for CYP2C9 and CYP3A4 Substrates

M. Mohutsky, S. Hall, D. Bedwell, 2017, Drug Metabolism and Disposition.

The Impact of the Hepatocyte-to-Plasma pH Gradient on the Prediction of Hepatic Clearance and Drug-Drug Interactions for CYP2D6 Substrates

M. Mohutsky, S. Hall, D. Bedwell, 2016, Drug Metabolism and Disposition.

Ablation of Both Organic Cation Transporter (Oct)1 and Oct2 Alters Metformin Pharmacokinetics but Has No Effect on Tissue Drug Exposure and Pharmacodynamics

J. W. Higgins, D. Bedwell, M. Zamek-Gliszczynski, 2012, Drug Metabolism and Disposition.

Characterization of SAGE Mdr1a (P-gp), Bcrp, and Mrp2 Knockout Rats Using Loperamide, Paclitaxel, Sulfasalazine, and Carboxydichlorofluorescein Pharmacokinetics

J. W. Higgins, D. Bedwell, M. Zamek-Gliszczynski, 2012, Drug Metabolism and Disposition.

paclitaxel, sulfasalazine, and carboxydichlorofluorescein pharmacokinetics

J. W. Higgins, D. Bedwell, M. Zamek-Gliszczynski, 2012 .

Difference in the Pharmacokinetics and Hepatic Metabolism of Antidiabetic Drugs in Zucker Diabetic Fatty and Sprague-Dawley Rats

K. Cassidy, M. Mohutsky, J. Cramer, 2016, Drug Metabolism and Disposition.

Performance of ultramicrofibre cleaning technology with or without addition of a novel copper-based biocide.

V. Gant, A. Jeanes, D. Bedwell, 2010, The Journal of hospital infection.

Patterns of antibody response in humans to the anthrax vaccine adsorbed (AVA) primary (six-dose) series.

D. Bedwell, K. Mckee, P. Pittman, 2006, Vaccine.

Discovery of (1S,2R,3S,4S,5R,6R)-2-Amino-3-[(3,4-difluorophenyl)sulfanylmethyl]-4-hydroxy-bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid Hydrochloride (LY3020371·HCl): A Potent, Metabotropic Glutamate 2/3 Receptor Antagonist with Antidepressant-Like Activity.

J. F. Soriano, P. Ornstein, S. Atwell, 2016, Journal of medicinal chemistry.

Finding a benchmark for monitoring hospital cleanliness.

C. Robertson, S. Dancer, S J Dancer, 2011, The Journal of hospital infection.

Development of a rapid and sensitive multiple reaction monitoring proteomic approach for quantification of transporters in human liver tissue.

D. Bedwell, K. Ruterbories, Jeffrey J Alberts, 2017, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

In Vitro Characterization of the Bioconversion of Pomaglumetad Methionil, a Novel Metabotropic Glutamate 2/3 Receptor Agonist Peptide Prodrug

M. Mohutsky, D. Bedwell, K. Ruterbories, 2015, Drug Metabolism and Disposition.

Hepatic OATP-mediated clearance in the Beagle dog: assessing in vitro-in vivo relationships and applying cross species empirical scaling factors to improve prediction of human clearance

K. Hillgren, A. Galetin, J. Houston, 2018 .

Finding a benchmark for monitoring hospital cleanliness.

C. Robertson, S. Dancer, D. Bedwell, 2011, The Journal of hospital infection.

Impact of Heterotropic Allosteric Modulation on the Time-Dependent Inhibition of Cytochrome P450 3A4

D. Bedwell, T. Abraham, L. Rougée, 2023, Drug Metabolism and Disposition.

Development of a rapid and sensitive multiple reaction monitoring proteomic approach for quantification of transporters in human liver tissue.

D. Bedwell, K. Ruterbories, Jeffrey J Alberts, 2017, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.