Binfeng Xia

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A Simplified PBPK Modeling Approach for Prediction of Pharmacokinetics of Four Primarily Renally Excreted and CYP3A Metabolized Compounds During Pregnancy

Tycho Heimbach, Binfeng Xia, T. Heimbach, 2013, The AAPS Journal.

A canine biorelevant dissolution method for predicting in vivo performance of orally administered sustained release matrix tablets

A. Bak, S. Bhardwaj, P. L. Walsh, 2016, Drug development and industrial pharmacy.

IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling strategies.

M. Jamei, L. Aarons, M. Bolger, 2020, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Physiologically based pharmacokinetic modeling for assessing the clinical drug-drug interaction of alisporivir.

T. Heimbach, Imad Hanna, G. Sunkara, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Development of a Novel Oral Cavity Compartmental Absorption and Transit Model for Sublingual Administration: Illustration with Zolpidem

V. Lukacova, F. Kesisoglou, Binfeng Xia, 2015, The AAPS Journal.

Pharmacokinetics of Subcutaneous Dupilumab Injection With an Autoinjector Device or Prefilled Syringe

John D. Davis, Christine R. Xu, Binfeng Xia, 2022, Clinical pharmacology in drug development.

Integration of Precipitation Kinetics From an In Vitro, Multicompartment Transfer System and Mechanistic Oral Absorption Modeling for Pharmacokinetic Prediction of Weakly Basic Drugs.

F. Kesisoglou, J. D. Ehrick, Binfeng Xia, 2019, Journal of pharmaceutical sciences.

Physiologically‐Based Pharmacokinetic Modeling in Renal and Hepatic Impairment Populations: A Pharmaceutical Industry Perspective

Andy Z. X. Zhu, Yuan Chen, I. Poggesi, 2020, Clinical pharmacology and therapeutics.

Effect of TPGS surfactant on dissolution sensitivity of a poorly water-soluble drug using high-shear wet granulation

S. Sotthivirat, Binfeng Xia, Chad D. Brown, 2020 .

Case Studies for Practical Food Effect Assessments across BCS/BDDCS Class Compounds using In Silico, In Vitro, and Preclinical In Vivo Data

Tycho Heimbach, Binfeng Xia, T. Heimbach, 2012, The AAPS Journal.

Case Studies for Practical Food Effect Assessments across BCS/BDDCS Class Compounds using In Silico, In Vitro, and Preclinical In Vivo Data

T. Heimbach, Tsu-han Lin, Binfeng Xia, 2012, The AAPS Journal.

Development of a Novel Oral Cavity Compartmental Absorption and Transit Model for Sublingual Administration: Illustration with Zolpidem

V. Lukacova, F. Kesisoglou, Binfeng Xia, 2015, The AAPS Journal.

Preclinical pharmacokinetics and metabolism of MNP001, a piperidine analog of 3‐carbamyl compounds

Binfeng Xia, L. M. Fox, Desuo Wang, 2011, Biopharmaceutics & drug disposition.

HPLC/MS/MS analysis of 3-carbamyl-4-methylpyrrole analog MNP001, a highly potent antihypertensive agent, in rat plasma.

Binfeng Xia, L. M. Fox, Desuo Wang, 2009, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Nilotinib preclinical pharmacokinetics and practical application toward clinical projections of oral absorption and systemic availability

T. Heimbach, Tsu-han Lin, Binfeng Xia, 2012, Biopharmaceutics & drug disposition.

Food Effect Projections via Physiologically Based Pharmacokinetic Modeling: Predictive Case Studies.

Filippos Kesisoglou, Neil Parrott, Tycho Heimbach, 2019, Journal of pharmaceutical sciences.

Atypical Kinetics of Valproic Acid Glucuronidation In vitro and In vivo inHumans

H. Wong, Sanjeev Kumar, J. Kenny, 2012 .

Utility of Physiologically Based Modeling and Preclinical In Vitro/In Vivo Data to Mitigate Positive Food Effect in a BCS Class 2 Compound

Hefei Zhang, Tycho Heimbach, Binfeng Xia, 2013, AAPS PharmSciTech.

Application of Physiologically Based Absorption Modeling to Formulation Development of a Low Solubility, Low Permeability Weak Base: Mechanistic Investigation of Food Effect

Hefei Zhang, Tycho Heimbach, Steven Novick, 2014, AAPS PharmSciTech.

Utility of Physiologically Based Modeling and Preclinical In Vitro/In Vivo Data to Mitigate Positive Food Effect in a BCS Class 2 Compound

T. Heimbach, Tsu-han Lin, Binfeng Xia, 2013, AAPS PharmSciTech.

Comparison of Deconvolution-Based and Absorption Modeling IVIVC for Extended Release Formulations of a BCS III Drug Development Candidate

F. Kesisoglou, N. Agrawal, Binfeng Xia, 2015, The AAPS Journal.

Novel physiologically based pharmacokinetic modeling of patupilone for human pharmacokinetic predictions

Tycho Heimbach, Binfeng Xia, T. Heimbach, 2012, Cancer Chemotherapy and Pharmacology.

Application of Physiologically Based Absorption Modeling to Formulation Development of a Low Solubility, Low Permeability Weak Base: Mechanistic Investigation of Food Effect

T. Heimbach, Tsu-han Lin, Binfeng Xia, 2014, AAPS PharmSciTech.

A Simplified PBPK Modeling Approach for Prediction of Pharmacokinetics of Four Primarily Renally Excreted and CYP3A Metabolized Compounds During Pregnancy

T. Heimbach, Binfeng Xia, Rakesh Gollen, 2013, The AAPS Journal.