D. Plowchalk

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Simulation of Human Intravenous and Oral Pharmacokinetics of 21 Diverse Compounds Using Physiologically Based Pharmacokinetic Modelling

Hannah M Jones, Maurice Dickins, Barry C Jones, 2011, Clinical pharmacokinetics.

A physiologically based pharmacokinetic model for nicotine disposition in the Sprague-Dawley rat.

M E Andersen, M. Andersen, J. D. Debethizy, 1992, Toxicology and applied pharmacology.

Reproductive toxicity of cyclophosphamide in the C57BL/6N mouse: 2. Effects on uterine structure and function.

D. Mattison, D. Plowchalk, M. J. Meadows, 1992, Reproductive toxicology.

Phosphoramide mustard is responsible for the ovarian toxicity of cyclophosphamide.

D. Mattison, D. Plowchalk, Donald R. Mattison, 1991, Toxicology and applied pharmacology.

A biologically based risk assessment for vinyl acetate-induced cancer and noncancer inhalation toxicity.

M E Andersen, M S Bogdanffy, M. Andersen, 1999, Toxicological sciences : an official journal of the Society of Toxicology.

The Sulfonylurea Glipizide Does Not Inhibit Ischemic Preconditioning in Anesthetized Rabbits

Carolyn B Levy, W. Soeller, J. Treadway, 2005, Cardiovascular Drugs and Therapy.

Physiologically based modeling of vinyl acetate uptake, metabolism, and intracellular pH changes in the rat nasal cavity.

M. Andersen, M. Bogdanffy, D. Plowchalk, 1997, Toxicology and applied pharmacology.

An EP2 receptor-selective prostaglandin E2 agonist induces bone healing

S. Vukicevic, V. Paralkar, F. Borovečki, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Drug Metabolites as Cytochrome P450 Inhibitors: A Retrospective Analysis and Proposed Algorithm for Evaluation of the Pharmacokinetic Interaction Potential of Metabolites in Drug Discovery and Development

A. Kalgutkar, R. Obach, Louis Leung, 2013, Drug Metabolism and Disposition.

Special Section on Prediction of Human Pharmacokinetic Parameters from In Vitro Systems Drug Metabolites as Cytochrome P450 Inhibitors: A Retrospective Analysis and Proposed Algorithm for Evaluation of the Pharmacokinetic Interaction Potential of Metabolites in Drug Discovery and Development

A. Kalgutkar, R. Obach, Louis Leung, 2013 .

Comparison of random and serial sections in assessment of ovarian toxicity.

D. Mattison, I. Sipes, D. Plowchalk, 1991, Reproductive toxicology.

Novel, Selective Vitamin D Analog Suppresses Parathyroid Hormone in Uremic Animals and Postmenopausal Women

H. DeLuca, M. Clagett-Dame, D. Plowchalk, 2014, American Journal of Nephrology.

The effect of benzo(a)pyrene on murine ovarian and corpora lutea volumes.

D. Mattison, D. Plowchalk, M. Miller, 1992, American journal of obstetrics and gynecology.

The nitrosation of nicotine: a kinetic study.

W. S. Caldwell, J. D. Debethizy, J. M. Greene, 1991, Chemical research in toxicology.

Biological Monitoring of the Human Placenta

D. Mattison, D. Plowchalk, Richard K. Miller, 1988 .

Application of CYP3A4 in vitro data to predict clinical drug-drug interactions; predictions of compounds as objects of interaction.

Alex Phipps, R Scott Obach, Maurice Dickins, 2008, British journal of clinical pharmacology.

Development of a physiologically based pharmacokinetic model for estradiol in rats and humans: a biologically motivated quantitative framework for evaluating responses to estradiol and other endocrine-active compounds.

Justin Teeguarden, J. Teeguarden, David R Plowchalk, 2002, Toxicological sciences : an official journal of the Society of Toxicology.

Reproductive toxicity of cyclophosphamide in the C57BL/6N mouse: 1. Effects on ovarian structure and function.

D. Mattison, D. Plowchalk, 1992, Reproductive toxicology.

Analysis of Vinyl Acetate Metabolism in Rat and Human Nasal Tissues by an in Vitro Gas Uptake Technique

R. Sarangapani, S. Frame, M. Bogdanffy, 1998 .

Analysis of vinyl acetate metabolism in rat and human nasal tissues by an in vitro gas uptake technique.

R. Sarangapani, S. Frame, M. Bogdanffy, 1998, Toxicological sciences : an official journal of the Society of Toxicology.

Reproductive toxicity: male and female reproductive systems as targets for chemical injury.

D. Mattison, D. Plowchalk, A. Malek, 1990, The Medical clinics of North America.

Mode-of-action-based dosimeters for interspecies extrapolation of vinyl acetate inhalation risk.

M E Andersen, M S Bogdanffy, M. Andersen, 2001, Inhalation toxicology.

Results of bococizumab, a monoclonal antibody against proprotein convertase subtilisin/kexin type 9, from a randomized, placebo-controlled, dose-ranging study in statin-treated subjects with hypercholesterolemia.

C. Ballantyne, H. Bays, A. Cropp, 2015, The American journal of cardiology.

Prediction of drug clearance in a smoking population: modeling the impact of variable cigarette consumption on the induction of CYP1A2

K. Rowland Yeo, D. Plowchalk, 2012, European Journal of Clinical Pharmacology.

Ovarian Morphometric Changes following Cyclophosphamide Treatment

D. Mattison, D. Plowchalk, 1989 .

=EFFICACY AND SAFETY OF BOCOCIZUMAB (RN316/PF-04950615), A MONOCLONAL ANTIBODY AGAINST PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 IN STATIN-TREATED HYPERCHOLESTEROLEMIC SUBJECTS: RESULTS FROM A RANDOMIZED, PLACEBO-CONTROLLED, DOSE-RANGING STUDY (NCT: 01592240)

C. Ballantyne, H. Bays, A. Cropp, 2014 .

Evaluation of Various Static In Vitro–In Vivo Extrapolation Models for Risk Assessment of the CYP3A Inhibition Potential of an Investigational Drug

J Snoeys, S D Hall, L Zhang, 2014, Clinical pharmacology and therapeutics.

Comparison of Different Algorithms for Predicting Clinical Drug-Drug Interactions, Based on the Use of CYP3A4 in Vitro Data: Predictions of Compounds as Precipitants of Interaction

Alex Phipps, Kuresh Youdim, Maurice Dickins, 2009, Drug Metabolism and Disposition.

ROLE OF PROLACTIN IN CHLORO-S-TRIAZINE RAT MAMMARY TUMORIGENESIS

L. G. Davis, C. V. Van Pelt, J. Cook, 2000, Drug and chemical toxicology.

Effects of manganese (Mn++) and iron (Fe+++) on magnetic resonance imaging (MRI) characteristics of human placenta and amniotic fluid.

D. Mattison, P. Thomford, D R Mattison, 1987, Physiological chemistry and physics and medical NMR.

The Effect of Smoking on Oogenesis, Fertilization, and Implantation

D. Mattison, D. Plowchalk, M. Meadows, 1989 .

A. Kalgutkar, Louis Leung, Ernesto Callegari, 2013, Drug Metabolism and Disposition.

Prediction of drug clearance in a smoking population: modeling the impact of variable cigarette consumption on the induction of CYP1A2

K. Rowland Yeo, Karen Rowland Yeo, D. Plowchalk, 2012, European Journal of Clinical Pharmacology.

Pharmacokinetics, pharmacodynamics, and safety of bococizumab, a monoclonal antibody against proprotein convertase subtilisin/kexin type 9, in healthy subjects when administered in co‐mixture with recombinant human hyaluronidase: A phase 1 randomized trial

Almasa Bass, A. Płotka, D. Plowchalk, 2018, Health science reports.