U. Braun

发表

PKD1 Protein Is Involved in Reactive Oxygen Species-mediated Mitochondrial Depolarization in Cooperation with Protein Kinase Cδ (PKCδ)*

M. Leitges, Thianzhou Zhang, Philipp Sell, 2015, The Journal of Biological Chemistry.

The critical role of atypical protein kinase C in activating hepatic SREBP-1 c and NF k B in obesity Mini

Robert V Farese, U. Varanasi, M. Leitges, 2009 .

The critical role of atypical protein kinase C in activating hepatic SREBP-1c and NFkappaB in obesity.

M. Sajan, R. Farese, U. Varanasi, 2009, Journal of lipid research.

AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC.

E. Van Obberghen, M. Sajan, R. Farese, 2010, American journal of physiology. Endocrinology and metabolism.

Impairment of insulin-stimulated glucose transport and ERK activation by adipocyte-specific knockout of PKC-λ produces a phenotype characterized by diminished adiposity and enhanced insulin suppression of hepatic gluconeogenesis

G. Shulman, M. Sajan, R. Farese, 2013, Adipocyte.

PKD3 deficiency causes alterations in microtubule dynamics during the cell cycle

M. Leitges, U. Braun, Tianzhou Zhang, 2016, Cell cycle.

The kinase PKD3 provides negative feedback on cholesterol and triglyceride synthesis by suppressing insulin signaling

G. Sumara, A. Schulze, M. Heikenwalder, 2019, Science Signaling.

PKCλ haploinsufficiency prevents diabetes by a mechanism involving alterations in hepatic enzymes.

G. Shulman, M. Sajan, R. Farese, 2014, Molecular endocrinology.

Correction of metabolic abnormalities in a rodent model of obesity, metabolic syndrome, and type 2 diabetes mellitus by inhibitors of hepatic protein kinase C-ι.

C. Kahn, A. Fields, M. Sajan, 2012, Metabolism: clinical and experimental.

Inhibition of PKCepsilon improves glucose-stimulated insulin secretion and reduces insulin clearance.

G. Cooney, D. R. Laybutt, J. Burchfield, 2007, Cell metabolism.

Brain Insulin Signaling Is Increased in Insulin-Resistant States and Decreases in FOXOs and PGC-1α and Increases in Aβ1–40/42 and Phospho-Tau May Abet Alzheimer Development

M. Sajan, R. Farese, M. Leitges, 2016, Diabetes.

Protein kinase D1 drives pancreatic acinar cell reprogramming and progression to intraepithelial neoplasia

D. Radisky, P. Storz, H. Döppler, 2015, Nature Communications.

Defective IgG2a/2b Class Switching in PKCα−/− Mice1

G. Baier, M. Leitges, N. Hermann-Kleiter, 2006, The Journal of Immunology.

a Defective IgG2a/2b Class Switching in PKC

G. Baier, M. Leitges, Thomas Gruber, 2006 .

Redundant Role of Protein Kinase C Delta and Epsilon during Mouse Embryonic Development

M. Leitges, F. Sacher, Sergio Carracedo, 2014, PloS one.

Functional comparison of protein domains within aPKCs involved in nucleocytoplasmic shuttling

M. Leitges, U. Braun, Sebastian Seidl, 2012, Biology Open.

Exacerbated vein graft arteriosclerosis in protein kinase Cδ–null mice

Qingbo Xu, M. Mayr, U. Mayr, 2001 .

Exacerbated vein graft arteriosclerosis in protein kinase Cdelta-null mice.

M. Mayr, U. Mayr, G. Baier, 2001, The Journal of clinical investigation.

Targeted Disruption of the ζPKC Gene Results in the Impairment of the NF-κB Pathway

Juan F. García, Pilar Martín, A. Durán, 2001 .

Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway.

A. Durán, M. Diaz-Meco, J. Moscat, 2001, Molecular cell.

Inhibition of PKCɛ Improves Glucose-Stimulated Insulin Secretion and Reduces Insulin Clearance

G. Cooney, D. R. Laybutt, J. Burchfield, 2007 .

Atypical PKC controls β-secretase expression and thereby regulates production of Alzheimer plaque precursor Aβ in brain and insulin receptor degradation in liver.

Robert V Farese, M. Sajan, M. Leitges, 2020 .

ERK1-independent α-secretase cut of β-amyloid precursor protein via M1 muscarinic receptors and PKCα/ε

G. Pagès, F. Checler, B. Vincent, 2011, Molecular and Cellular Neuroscience.

Protein kinase C betaII and PKCiota/lambda: collaborating partners in colon cancer promotion and progression.

A. Fields, M. Leitges, N. Murray, 2009, Cancer research.

Protein Kinase C- (cid:1) Knockout in Embryonic Stem Cells and Adipocytes Impairs Insulin-Stimulated Glucose Transport

Atsushi Miura, M. Sajan, R. Farese, 2022 .

Expression pattern of protein kinase C δ during mouse embryogenesis

M. Leitges, Sergio Carracedo, U. Braun, 2013, BMC Developmental Biology.

Muscle-specific knockout of PKC-λ impairs glucose transport and induces metabolic and diabetic syndromes

C. Kahn, G. Shulman, Hong Yang, 2007 .

Muscle-specific knockout of PKC-lambda impairs glucose transport and induces metabolic and diabetic syndromes.

C. Kahn, G. Shulman, Hong Yang, 2007, The Journal of clinical investigation.

Defective IgG2a/2b class switching in PKC alpha-/- mice.

G. Baier, M. Leitges, N. Hermann-Kleiter, 2006, Journal of immunology.

Expression pattern of Protein Kinase C ϵ during mouse embryogenesis

M. Leitges, Sergio Carracedo, U. Braun, 2013, BMC developmental biology.

The role of individual protein kinase C isoforms in mouse mast cell function and their targeting by the immunomodulatory parasitic worm product, ES-62

M. Harnett, W. Harnett, M. Leitges, 2015, Immunology letters.

Phenotypical Analysis of Atypical PKCs In Vivo Function Display a Compensatory System at Mouse Embryonic Day 7.5

A. Kispert, M. Leitges, N. Roos, 2013, PloS one.

Isoform-specific contribution of protein kinase C to prion processing

F. Checler, P. Auberger, M. Cissé, 2008, Molecular and Cellular Neuroscience.

AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC.

M. Sajan, R. Farese, F. Foufelle, 2010, American journal of physiology. Endocrinology and metabolism.