A. Houghton

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Peripheral Morphine Administration Blocks the Development of Hyperalgesia and Allodynia after Bone Damage in the Rat

K. Westlund, A. Houghton, J. G. Valdez, 1998, Anesthesiology.

Enhanced withdrawal responses to mechanical and thermal stimuli after bone injury

K. Westlund, A. Houghton, E. Hewitt, 1997, Pain.

fMRI study of the role of glutamate NMDA receptor in the olfactory processing in monkeys

J. Uslaner, J. Evelhoch, C. Hines, 2018, PloS one.

Distinct BOLD fMRI Responses of Capsaicin-Induced Thermal Sensation Reveal Pain-Related Brain Activation in Nonhuman Primates

S. Derbyshire, J. Evelhoch, R. Baumgartner, 2016, PloS one.

Dorsal column lesion prevents mechanical hyperalgesia and allodynia in osteotomy model

K. Westlund, A. Houghton, E. Hewitt, 1999, Pain.

Mrz 2/579, a fast kinetic NMDA channel blocker, reduces the development of morphine tolerance in awake rats

C. Parsons, P. Headley, A. Houghton, 2001, Pain.

S-(+)-3-isobutylgaba and its stereoisomer reduces the amount of inflammation and hyperalgesia in an acute arthritis model in the rat.

K. Westlund, A. Houghton, Y. Lu, 1998, The Journal of pharmacology and experimental therapeutics.

Association of respiratory failure with inhibition of NaV1.6 in the phrenic nerve

D. Henze, C. Regan, Yuxing Li, 2022, Channels.

Spinal section and opioid receptor blockade induce the appearance of Fos-like immunoreactivity in the spinal cord of the decerebrated rabbit

T. Carter, A. Houghton, R. Clarke, 1999, Neuroscience.

The involvement of tachykinin NK2 and NK3 receptors in central sensitization of a spinal withdrawal reflex in the decerebrated, spinalized rabbit

A. Houghton, R. Clarke, J. Ogilvie, 2000, Neuropharmacology.

Dorsal column lesions reverse the reduction of homecage activity in rats with pancreatitis

K. Westlund, A. Houghton, S. Kadura, 1997, Neuroreport.

The involvement of bulbospinal pathways in fentanyl-induced inhibition of spinal withdrawal reflexes in the decerebrated rabbit

A. Houghton, R. Clarke, J. Ogilvie, 1998, Pain.

Do nociceptive signals from the pancreas travel in the dorsal column?

K. Westlund, A. Houghton, Chia-Chuan Wang, 2001, Pain.

Tachykininergic tone in the spinal cord of the rabbit: Dependence on nociceptive input arising from invasive surgery

A. Houghton, R. Clarke, C. Gorringe, 1995, Neuroscience.

NK1-tachykinin receptors and prolonged, stimulus-evoked alterations in the excitability of withdrawal reflexes in the decerebrated and spinalized rabbit

A. Houghton, R. Clarke, 1995, Neuroscience.

Spinal 5‐HT‐receptors and tonic modulation of transmission through a withdrawal reflex pathway in the decerebrated rabbit

J. Harris, A. Houghton, R. Clarke, 1996, British journal of pharmacology.

Translational Pharmacokinetic–Pharmacodynamic Modeling of NaV1.7 Inhibitor MK-2075 to Inform Human Efficacious Dose

D. Henze, C. Gibson, R. Kraus, 2021, Frontiers in Pharmacology.

Application of Pharmacokinetic-Pharmacodynamic Modeling to Inform Translation of In Vitro NaV1.7 Inhibition to In Vivo Pharmacological Response in Non-human Primate

D. Henze, C. Gibson, Yuxing Li, 2020, Pharmaceutical Research.

Bilateral Sensory Abnormalities in Patients with Unilateral Neuropathic Pain; A Quantitative Sensory Testing (QST) Study

M. Struys, J. D. den Boer, R. Kortekaas, 2012, PloS one.

fMRI study of olfaction in the olfactory bulb and high olfactory structures of rats: Insight into their roles in habituation

Fuqiang Zhao, Donald S. Williams, Xiaohai Wang, 2016, NeuroImage.

PII: S0304-3959(00)00364-X

K. Westlund, A. Houghton, Chia-Chuan Wang, 2001 .

Enhancement and depression of spinal reflexes by 8‐hydroxy‐2‐(di‐n‐propylamino)tetralin in the decerebrated and spinalized rabbit: involvement of 5‐HT1A‐ and non‐5‐HT1A‐receptors

A. Houghton, R. Clarke, J. Ogilvie, 1997, British journal of pharmacology.

Somatosensory Profiles but Not Numbers of Somatosensory Abnormalities of Neuropathic Pain Patients Correspond with Neuropathic Pain Grading

M. Struys, J. D. den Boer, R. Kortekaas, 2012, PloS one.

Actions of kainate and AMPA selective glutamate receptor ligands on nociceptive processing in the spinal cord

P. Ornstein, E. Faber, P. Headley, 1998, Neuropharmacology.

Pharmacological validation of a novel nonhuman primate measure of thermal responsivity with utility for predicting analgesic effects

D. Henze, J. Uslaner, Joshua D. Vardigan, 2018, Journal of pain research.

Discovery of selective, orally bioavailable, N-linked arylsulfonamide Nav1.7 inhibitors with pain efficacy in mice.

Edward C Sherer, John Majercak, Deping Wang, 2017, Bioorganic & medicinal chemistry letters.

Functional imaging of olfaction by CBV fMRI in monkeys: Insight into the role of olfactory bulb in habituation

Fuqiang Zhao, Richard Hargreaves, Donald S. Williams, 2015, NeuroImage.

Nav1.7 target modulation and efficacy can be measured in nonhuman primate assays

D. Henze, Yuxing Li, R. Kraus, 2021, Science Translational Medicine.

fMRI study of olfactory processing in mice under three anesthesia protocols: Insight into the effect of ketamine on olfactory processing

Fuqiang Zhao, Xiangjun Meng, Andrea K. Houghton, 2020, NeuroImage.

Opioidergic modulation of spinal reflexes activated by mechanical stimulation of the heel in the decerebrated, spinalized rabbit

J. Harris, A. Houghton, R. Clarke, 1998, Experimental Brain Research.

fMRI study of the role of glutamate NMDA receptor in the olfactory adaptation in rats: Insights into cellular and molecular mechanisms of olfactory adaptation

Fuqiang Zhao, Xiaohai Wang, Hatim A. Zariwala, 2017, NeuroImage.

Benzoxazolinone aryl sulfonamides as potent, selective Nav1.7 inhibitors with in vivo efficacy in a preclinical pain model.

Michael A Rossi, D. Henze, J. Majercak, 2017, Bioorganic & medicinal chemistry letters.

fMRI study of olfaction in the olfactory bulb and high olfactory structures of rats: Insight into their roles in habituation

Hatim A. Zariwala, Donald S. Williams, J. Uslaner, 2016, NeuroImage.

Qualification of fMRI as a biomarker for pain in anesthetized rats by comparison with behavioral response in conscious rats

Fuqiang Zhao, Mangay Williams, Richard Hargreaves, 2014, NeuroImage.

An I2 imidazoline ligand, RS 45041, potentiates hyperalgesia in acute arthritis.

K. Westlund, A. Houghton, 1996, Neuroreport.

Endogenous adrenergic control of reflexes evoked by mechanical stimulation of the heel in the decerebrated rabbit

J. Harris, A. Houghton, R. Clarke, 2001, Neuroscience Letters.