I. Hazemann

发表

The integrative role of cryo electron microscopy in molecular and cellular structural biology

Alexandre Urzhumtsev, Igor Orlov, Leonid Andronov, 2017, Biology of the cell.

Virtual screening for inhibitors of human aldose reductase

Gerhard Klebe, Isabelle Hazemann, G. Klebe, 2004, Proteins.

Involvement of protein IF2 N domain in ribosomal subunit joining revealed from architecture and function of the full-length initiation factor

T. Steitz, J. Puglisi, C. Gualerzi, 2013, Proceedings of the National Academy of Sciences.

Comparison of hydrogen determination with X-ray and neutron crystallography in a human aldose reductase–inhibitor complex

A. Mitschler, A. Podjarny, D. Myles, 2006, European Biophysics Journal.

Importance of the Sequence-Directed DNA Shape for Specific Binding Site Recognition by the Estrogen-Related Receptor

D. Moras, S. Cianférani, B. Klaholz, 2017, Front. Endocrinol..

Neutron macromolecular crystallography with LADI-III.

E. Howard, A. Mitschler, A. Podjarny, 2010, Acta crystallographica. Section D, Biological crystallography.

X-ray-radiation-induced cooperative atomic movements in protein.

A. Joachimiak, V. Lunin, T. Petrova, 2009, Journal of molecular biology.

The atomic resolution structure of human aldose reductase reveals that rearrangement of a bound ligand allows the opening of the safety-belt loop.

G. Sheldrick, A. Joachimiak, T. Schneider, 2007, Acta crystallographica. Section D, Biological crystallography.

Ultrahigh-resolution study of protein atomic displacement parameters at cryotemperatures obtained with a helium cryostat.

A. Joachimiak, V. Lunin, T. Petrova, 2006, Acta crystallographica. Section D, Biological crystallography.

High-resolution neutron protein crystallography with radically small crystal volumes: application of perdeuteration to human aldose reductase.

A. van Dorsselaer, A. Mitschler, A. Podjarny, 2005, Acta crystallographica. Section D, Biological crystallography.

X-ray-induced deterioration of disulfide bridges at atomic resolution.

A. Joachimiak, V. Lunin, Youngchang Kim, 2010, Acta crystallographica. Section D, Biological crystallography.

Visualizing the Role of 2’-OH rRNA Methylations in the Human Ribosome Structure

B. Klaholz, A. Myasnikov, S. K. Natchiar, 2018, Biomolecules.

Visualization of chemical modifications in the human 80S ribosome structure

B. Klaholz, A. Myasnikov, S. K. Natchiar, 2017, Nature.

A novel nuclear receptor subfamily enlightens the origin of heterodimerization

Gabriel V. Markov, V. Laudet, D. Moras, 2022, BMC Biology.

X-rays-Induced Cooperative Atomic Movement in a Protein Crystal

A. Joachimiak, V. Lunin, Youngchang Kim, 2013 .

High-resolution cryo-EM performance comparison of two latest-generation cryo electron microscopes on the human ribosome.

B. Klaholz, I. Hazemann, Léo Fréchin, 2022, Journal of structural biology.

Factorizing selectivity determinants of inhibitor binding toward aldose and aldehyde reductases: structural and thermodynamic properties of the aldose reductase mutant Leu300Pro-fidarestat complex.

G. Klebe, O. El-Kabbani, A. Joachimiak, 2005, Journal of medicinal chemistry.

Structure–function insights reveal the human ribosome as a cancer target for antibiotics

V. Imbert, J. Peyron, B. Klaholz, 2016, Nature Communications.

Perdeuteration, purification, crystallization and preliminary neutron diffraction of an ocean pout type III antifreeze protein.

E. Howard, A. Mitschler, A. Podjarny, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

High-resolution structures of human aldose reductase holoenzyme in complex with stereoisomers of the potent inhibitor Fidarestat: stereospecific interaction between the enzyme and a cyclic imide type inhibitor.

T. Tomizaki, O. El-Kabbani, A. Mitschler, 2004, Journal of medicinal chemistry.

Atomic model building and refinement into high-resolution cryo-EM maps

B. Klaholz, A. Myasnikov, S. K. Natchiar, 2017 .

Focused classification and refinement in high-resolution cryo-EM structural analysis of ribosome complexes.

Ottilie von Loeffelholz, Isabelle Hazemann, Jean-François Ménétret, 2017, Current opinion in structural biology.

Structure of the protein core of translation initiation factor 2 in apo, GTP-bound and GDP-bound forms

C. Gualerzi, S. Marzi, A. Urzhumtsev, 2013, Acta crystallographica. Section D, Biological crystallography.

10 Integrative structure-function analysis of large nucleoprotein complexes

A. Urzhumtsev, B. Klaholz, A. Myasnikov, 2013 .

Volta phase plate data collection facilitates image processing and cryo-EM structure determination.

Radostin Danev, Bruno P Klaholz, Ottilie von Loeffelholz, 2018, Journal of structural biology.

Quantum model of catalysis based on a mobile proton revealed by subatomic x-ray and neutron diffraction studies of h-aldose reductase

Raul Cachau, Isabelle Hazemann, Oscar N Ventura, 2008, Proceedings of the National Academy of Sciences.

Probing the ultra-high resolution structure of aldose reductase with molecular modelling and noncovalent mass spectrometry.

Connie Darmanin, Alain Van Dorsselaer, Isabelle Hazemann, 2004, Bioorganic & medicinal chemistry.

Crystal packing modifies ligand binding affinity: The case of aldose reductase

Alain Van Dorsselaer, Isabelle Hazemann, Alberto Podjarny, 2012, Proteins.

Asymmetric dimerization in a transcription factor superfamily is promoted by allosteric interactions with DNA

Gabriel V. Markov, D. Moras, B. Klaholz, 2023, Nucleic acids research.

Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with fidarestat and minalrestat: Implications for the binding of cyclic imide inhibitors

T. Tomizaki, C. Schulze-Briese, O. El-Kabbani, 2004, Proteins.

Quantum model of catalysis based on a mobile proton revealed by subatomic x-ray and neutron diffraction studies of h-aldose reductase

A. Joachimiak, P. Afonine, R. Cachau, 2008, Proceedings of the National Academy of Sciences.

Neutron macromolecular crystallography with LADI-III.

E. Howard, A. Mitschler, A. Podjarny, 2010, Acta crystallographica. Section D, Biological crystallography.

Perdeuteration, purification, crystallization and preliminary neutron diffraction of an ocean pout type III antifreeze protein.

E. Howard, A. Mitschler, A. Podjarny, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.