D. Gioeli

S. Peirce, M. Jameson, D. Gioeli, 2018, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

Immunostaining for activated extracellular signal-regulated kinases in cells and tissues.

M. Weber, M. Zečević, D. Gioeli, 2001, Methods in enzymology.

Androgen Receptor Phosphorylation

J. Shabanowitz, D. Hunt, S. Ficarro, 2002, The Journal of Biological Chemistry.

Activation of mitogen-activated protein kinase associated with prostate cancer progression.

H. Frierson, G. Petroni, J. Mandell, 1999, Cancer research.

Ruthenium(II) tris(bipyridine)-centered poly(ethylenimine) for gene delivery.

S. J. Payne, C. Fraser, Gina L. Fiore, 2007, Biomacromolecules.

Inactivation of the CRL4-CDT2-SET8/p21 ubiquitylation and degradation axis underlies the therapeutic efficacy of pevonedistat in melanoma

C. Slingluff, T. Abbas, Mouadh Benamar, 2016, EBioMedicine.

Combinatorial drug screening and molecular profiling reveal diverse mechanisms of intrinsic and adaptive resistance to BRAF inhibition in V600E BRAF mutant melanomas

Emanuel F. Petricoin, Mark R. Conaway, Brian Capaldo, 2016 .

Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha

I. Nakano, E. Sulman, M. Mayo, 2018, Neuro-oncology.

Androgen receptor phosphorylation: biological context and functional consequences.

Yulia Koryakina, D. Gioeli, Huy Q. Ta, 2014, Endocrine-related cancer.

IGF1R and Src inhibition induce synergistic cytotoxicity in HNSCC through inhibition of FAK

E. Petricoin, S. Bekiranov, J. Wulfkuhle, 2021, Scientific Reports.

The convergence of DNA damage checkpoint pathways and androgen receptor signaling in prostate cancer.

D. Gioeli, Huy Q. Ta, 2014, Endocrine-related cancer.

Receptor for activated C kinase 1 (RACK1) and Src regulate the tyrosine phosphorylation and function of the androgen receptor.

T. Vomastek, S. Kraus, D. Gioeli, 2006, Cancer research.

Signal transduction in prostate cancer progression.

D. Gioeli, 2005, Clinical science.

Rap2 regulates androgen sensitivity in human prostate cancer cells

M. Conaway, D. Theodorescu, D. Bigler, 2007, The Prostate.

A detailed characterization of stepwise activation of the androgen receptor variant 7 in prostate cancer cells

Hong Liu, G. Raj, Dede N. Ekoue, 2020, Oncogene.

Discovery of a novel long noncoding RNA overlapping the LCK gene that regulates prostate cancer cell growth

H. Frierson, M. Conaway, G. Raj, 2019, Molecular Cancer.

MST1 is a multifunctional caspase-independent inhibitor of androgenic signaling.

M. Freeman, N. Mukhopadhyay, D. Gioeli, 2011, Cancer research.

Checkpoint Kinase 2 Negatively Regulates Androgen Sensitivity and Prostate Cancer Cell Growth.

H. Frierson, M. Conaway, J. Larner, 2015, Cancer research.

Identification of additional complementation groups that regulate genomic instability

T. Tlsty, B. Weissman, I. Hall, 1997, Genes, chromosomes & cancer.

Systems Analysis of Adaptive Responses to MAP Kinase Pathway Blockade in BRAF Mutant Melanoma

E. Petricoin, S. Bekiranov, A. Mackey, 2015, PloS one.

Preventing the Androgen Receptor N/C Interaction Delays Disease Onset in a Mouse Model of SBMA.

D. Merry, Tamar R Berger, B. Paschal, 2015, Cell reports.

Constitutive activation of the Ras/mitogen-activated protein kinase signaling pathway promotes androgen hypersensitivity in LNCaP prostate cancer cells.

E. Bissonette, R. Sikes, D. Gioeli, 2003, Cancer research.

Activation of Mitogen-Activated Protein Kinase Associated with Prostate Cancer Progression 1

H. Frierson, G. Petroni, J. Mandell, 1999 .

Validation of a multicellular tumor microenvironment system for modeling patient tumor biology and drug response

Kristopher D. Rawls, E. Petricoin, J. Wulfkuhle, 2021, Scientific Reports.

Development of a multicellular pancreatic tumor microenvironment system using patient-derived tumor cells.

E. Petricoin, J. Parsons, J. Wulfkuhle, 2019, Lab on a chip.

Restoration of PTEN expression alters the sensitivity of prostate cancer cells to EGFR inhibitors

M. Conaway, D. Theodorescu, D. Gioeli, 2008, The Prostate.

Analysis of oncogene, tumor suppressor gene, and chromosomal alterations in HeLa × osteosarcoma somatic cell hybrids

B. Weissman, R. Isfort, D. Gioeli, 1999, Molecular carcinogenesis.

Cell-cycle-dependent regulation of androgen receptor function.

K. Knudsen, Yulia Koryakina, D. Gioeli, 2015, Endocrine-related cancer.

CDK9 regulates AR promoter selectivity and cell growth through serine 81 phosphorylation.

W. Hahn, I. Xenarios, J. Shabanowitz, 2010, Molecular endocrinology.

Ras signaling in prostate cancer progression

Daniel Gioeli, Michael J Weber, D. Gioeli, 2004, Journal of cellular biochemistry.

The Dynamics of the Cell Signaling Network; Implications for Targeted Therapies

D. Gioeli, 2011 .

Androgen Receptor Regulate the Tyrosine Phosphorylation and Function of the Receptor for Activated C Kinase 1 ( RACK 1 ) and Src

T. Vomastek, D. Gioeli, Vicki L. Gordon, 2006 .

Combinatorial drug screening identifies compensatory pathway interactions and adaptive resistance mechanisms

Mark Axelrod, Daniel Gioeli, M. Conaway, 2013, Oncotarget.

Integration of rapid signaling events with steroid hormone receptor action in breast and prostate cancer.

S. Hammes, C. Lange, P. Marker, 2007, Annual review of physiology.

Post-translational modification of the androgen receptor

Daniel Gioeli, B. Paschal, D. Gioeli, 2012, Molecular and Cellular Endocrinology.

Transient, ligand-dependent arrest of the androgen receptor in subnuclear foci alters phosphorylation and coactivator interactions.

M. Conaway, B. E. Black, B. Paschal, 2004, Molecular endocrinology.

The Androgen Receptor Acetylation Site Regulates cAMP and AKT but Not ERK-induced Activity*

Mahadev Rao, Chenguang Wang, R. Pestell, 2004, Journal of Biological Chemistry.

Preventing the Androgen R eceptor N / C Interaction Delays Disease Onset in a Mouse Model of SBMA Graphical Abstract Highlights

D. Merry, Tamar R Berger, B. Paschal, 2015 .

Identification of Kinases Regulating Prostate Cancer Cell Growth Using an RNAi Phenotypic Screen

M. Conaway, D. Gioeli, H. Holemon, 2012, PloS one.

Karyopherin α7 (KPNA7), a divergent member of the importin α family of nuclear import receptors

B. Paschal, D. Gioeli, Adam Spencer, 2010, BMC Cell Biology.

Dasatinib inhibits site-specific tyrosine phosphorylation of androgen receptor by Ack1 and Src kinases

Daniel Gioeli, Y. Whang, M. Karaca, 2010, Oncogene.

CD46 targeted 212Pb alpha particle radioimmunotherapy for prostate cancer treatment

S. Bidlingmaier, Youngho Seo, Bin Liu, 2023, bioRxiv.

Stress kinase signaling regulates androgen receptor phosphorylation, transcription, and localization.

B. E. Black, S. T. Eblen, B. Paschal, 2006, Molecular endocrinology.

Antitumor effect of insulin‐like growth factor‐1 receptor inhibition in head and neck squamous cell carcinoma

H. Frierson, E. Petricoin, S. Bekiranov, 2020, The Laryngoscope.

Role of the runt‐related transcription factor (RUNX) family in prostate cancer

Devin G. Roller, D. Gioeli, Devin G Roller, 2021, The FEBS journal.

Survivin in Insulin-Like Growth Factor-Induced Resistance to Lapatinib in Head and Neck Squamous Carcinoma Cells

A. Khalil, M. Jameson, D. Gioeli, 2019, Front. Oncol..

The androgen receptor does not directly regulate the transcription of DNA damage response genes

K. Sathyan, Devin G. Roller, M. Guertin, 2023, bioRxiv.

TRPS1 modulates chromatin accessibility to regulate estrogen receptor (ER) binding and ER target gene expression in luminal breast cancer cells

Michael J. Guertin, K. Sathyan, M. Guertin, 2023, bioRxiv.

Synthetic Lethal Screening with Small-Molecule Inhibitors Provides a Pathway to Rational Combination Therapies for Melanoma

Karin J Jensen, Mark Axelrod, Daniel Gioeli, 2012, Molecular Cancer Therapeutics.

The androgen receptor does not directly regulate the transcription of DNA damage response genes

K. Sathyan, Devin G. Roller, M. Guertin, 2023, bioRxiv.

The potentiative cytotoxic effect of IGF1R and EGFR inhibition on the Head and Neck Cancer Proteome

E. Petricoin, S. Bekiranov, J. Wulfkuhle, 2022, bioRxiv.

Synergistic apoptosis in head and neck squamous cell carcinoma cells by co‐inhibition of insulin‐like growth factor‐1 receptor signaling and compensatory signaling pathways

A. Khalil, E. Sharlow, M. Jameson, 2015, Head & neck.

Using Graph Representation Learning to Predict Salivary Cortisol Levels in Pancreatic Cancer Patients

Mehdi Boukhechba, Lee M. Ritterband, Philip I. Chow, 2021, Journal of Healthcare Informatics Research.

Discovery of a novel long noncoding RNA overlapping the LCK gene that regulates prostate cancer cell growth

Daniel Gioeli, H. Frierson, M. Conaway, 2019, Molecular Cancer.

PRAS40 Phosphorylation Correlates with Insulin-Like Growth Factor-1 Receptor-Induced Resistance to Epidermal Growth Factor Receptor Inhibition in Head and Neck Cancer Cells

E. Petricoin, J. Wulfkuhle, M. Jameson, 2020, Molecular Cancer Research.

Molecular Imaging of Prostate Cancer Targeting CD46 Using ImmunoPET

R. Flavell, F. Feng, S. Shen, 2020, Clinical Cancer Research.

CDK9 regulates AR promoter selectivity and cell growth through serine 81 phosphorylation.

W. Hahn, I. Xenarios, J. Shabanowitz, 2010, Molecular endocrinology.

αvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer through JNK1-Mediated Activation of Androgen Receptor.

D. Jain, P. Weinreb, S. Violette, 2016, Cancer research.

p70S6 kinase is a critical node that integrates HER-family and PI3 kinase signaling networks.

M. Conaway, E. Sharlow, M. Jameson, 2014, Cellular signalling.

Advances in Brief Activation of Mitogen-Activated Protein Kinase Associated with Prostate Cancer Progression 1

H. Frierson, G. Petroni, J. Mandell, 1999 .

MST1 is a multifunctional caspase-independent inhibitor of androgenic signaling.

M. Freeman, N. Mukhopadhyay, D. Gioeli, 2011, Cancer research.

Mobile sensing to advance tumor modeling in cancer patients: A conceptual framework

Philip I. Chow, L. Ritterband, K. Shaffer, 2023, Internet interventions.