Jingxin Wang

发表

Effects on membrane lateral pressure suggest permeation mechanisms for bacterial quorum signaling molecules.

W. Bentley, S. Sukharev, Varnika Roy, 2011, Biochemistry.

Dialkylamino-2,4-dihydroxybenzoic acids as easily synthesized analogues of platensimycin and platencin with comparable antibacterial properties.

H. Sintim, Jingxin Wang, 2011, Chemistry.

Oligoribonuclease is the primary degradative enzyme for pGpG in Pseudomonas aeruginosa that is required for cyclic-di-GMP turnover

Vincent T. Lee, C. Waters, V. Lee, 2015, Proceedings of the National Academy of Sciences.

CRISPR‐Mediated Enzyme Fragment Complementation Assay for Quantification of the Stability of Splice Isoforms

C. Lorson, Jingxin Wang, Shoutian Zhu, 2022, Chembiochem : a European journal of chemical biology.

Discovery of a potent GLUT inhibitor using rapafucin 3D microarrays.

Jun O. Liu, S. Sukumar, J. Locasale, 2019, Angewandte Chemie.

Discovery of a Potent GLUT Inhibitor from a Library of Rapafucins by Using 3D Microarrays

Jun O. Liu, S. Sukumar, J. Locasale, 2019, Angewandte Chemie.

DNA-based peroxidation catalyst--what is the exact role of topology on catalysis and is there a special binding site for catalysis?

Shizuka Nakayama, H. Sintim, Jingxin Wang, 2011, Chemistry.

Efforts towards the identification of simpler platensimycin analogues--the total synthesis of oxazinidinyl platensimycin.

V. Lee, H. Sintim, Jingxin Wang, 2009, Chemistry.

Mechanistic studies of a small-molecule modulator of SMN2 splicing

P. Schultz, Kristen A. Johnson, Jingxin Wang, 2018, Proceedings of the National Academy of Sciences.

Potent suppression of c-di-GMP synthesis via I-site allosteric inhibition of diguanylate cyclases with 2'-F-c-di-GMP.

Vincent T. Lee, Jie Zhou, V. Lee, 2013, Bioorganic & medicinal chemistry.

Inhibitors of fatty acid synthesis in prokaryotes and eukaryotes as anti-infective, anticancer and anti-obesity drugs.

H. Sintim, Jingxin Wang, Ryan Hudson, 2012, Future medicinal chemistry.

Remote C-H functionalization: using the N-O moiety as an atom-economical tether to obtain 1,5- and the rare 1,7-C-H insertions.

Deana Jaber, B. Štefane, H. Sintim, 2010, Angewandte Chemie.

Paradigm shift in discovering next-generation anti-infective agents: targeting quorum sensing, c-di-GMP signaling and biofilm formation in bacteria with small molecules.

Lei Yan, Shizuka Nakayama, H. Sintim, 2010, Future medicinal chemistry.

Inhibition of SARS-CoV-2 by Targeting Conserved Viral RNA Structures and Sequences

Jingxin Wang, Zhichao Tang, Junxing Zhao, 2021, Frontiers in Chemistry.

Rapamycin-inspired macrocycles with new target specificity

Jun O. Liu, G. Fischer, C. Tse, 2018, Nature Chemistry.

Conservative change to the phosphate moiety of cyclic diguanylic monophosphate remarkably affects its polymorphism and ability to bind DGC, PDE, and PilZ proteins.

Jie Zhou, V. Lee, G. P. Donaldson, 2011, Journal of the American Chemical Society.

Cellular Target Deconvolution of Small Molecules Using a Selection-Based Genetic Screening Platform

H. M. Petrassi, J. Douglas, P. Gao, 2022, ACS central science.

Differential radial capillary action of ligand assay for high-throughput detection of protein-metabolite interactions

V. Lee, H. Sintim, Jingxin Wang, 2011, Proceedings of the National Academy of Sciences.

RNA-Targeting Splicing Modifiers: Drug Development and Screening Assays

Z. Boskovic, Jingxin Wang, Junxing Zhao, 2021, Molecules.

Recognition of single-stranded nucleic acids by small-molecule splicing modulators

Jinan Wang, M. Reibarkh, J. Douglas, 2021, Nucleic acids research.

Altering the communication networks of multispecies microbial systems using a diverse toolbox of AI-2 analogues.

William E Bentley, Sonja Gamby, Jingxin Wang, 2012, ACS chemical biology.

Synthetic analogs tailor native AI-2 signaling across bacterial species.

W. Bentley, J. E. Stewart, Varnika Roy, 2010, Journal of the American Chemical Society.

The RNA Architecture of the SARS-CoV-2 3′-Untranslated Region

J. Qiu, Jingxin Wang, Junxing Zhao, 2020, Viruses.

High-Throughput Screening Identifies Inhibitors for Parvovirus B19 Infection of Human Erythroid Progenitors

C. Escalante, J. Qiu, P. Xu, 2021, Journal of virology.

c-di-GMP can form remarkably stable G-quadruplexes at physiological conditions in the presence of some planar intercalators.

Ilana Kelsey, Shizuka Nakayama, H. Sintim, 2011, Chemical communications.

Octameric G8 c-di-GMP is an efficient peroxidase and this suggests that an open G-tetrad site can effectively enhance hemin peroxidation reactions

Benjamin T. Roembke, Shizuka Nakayama, H. Sintim, 2013 .

Structural and Biological Evaluations of a Non-Nucleoside STING Agonist Specific for Human STINGA230 Variants

Y. Li, Pingwei Li, Jingxin Wang, 2023, bioRxiv.

Biological screening of a diverse set of AI-2 analogues in Vibrio harveyi suggests that receptors which are involved in synergistic agonism of AI-2 and analogues are promiscuous.

Vincent Lee, Jingxin Wang, V. Lee, 2009, Chemical communications.

Chemical-guided SHAPE sequencing (cgSHAPE-seq) informs the binding site of RNA-degrading chimeras targeting SARS-CoV-2 5’ untranslated region

J. Qiu, Jingxin Wang, M. Selvaraju, 2023, bioRxiv.

Thiazole orange-induced c-di-GMP quadruplex formation facilitates a simple fluorescent detection of this ubiquitous biofilm regulating molecule.

Ilana Kelsey, Yiling Luo, V. Lee, 2011, Journal of the American Chemical Society.

Endo-S-c-di-GMP Analogues-Polymorphism and Binding Studies with Class I Riboswitch

Jie Zhou, H. Sintim, Jingxin Wang, 2012, Molecules.