T. Thai

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Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway.

Henry W. Long, R. Beroukhim, C. Paweletz, 2020, Cancer cell.

The Laminin–Nidogen Complex is a Ligand for a Specific Splice Isoform of the Transmembrane Protein Tyrosine Phosphatase LAR

H. Saito, T. Thai, P. O'grady, 1998, The Journal of cell biology.

Intrinsic immunogenicity of small cell lung carcinoma revealed by its cellular plasticity.

C. Paweletz, M. Tolstorukov, E. V. Van Allen, 2021, Cancer discovery.

Suppression of STING Associated with LKB1 Loss in KRAS-Driven Lung Cancer.

C. Paweletz, D. Barbie, Y. Mitsuishi, 2018, Cancer discovery.

Retinoblastoma inactivation induces a protumoral microenvironment via enhanced CCL2 secretion.

D. Barbie, Tomoaki Tanaka, N. Okada, 2019, Cancer research.

Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit.

Travis J Cohoon, N. Hacohen, J. Mesirov, 2014, Cancer discovery.

Autophagy Inhibition Dysregulates TBK1 Signaling and Promotes Pancreatic Inflammation

Kwok-Kin Wong, E. Oki, S. Ogino, 2016, Cancer Immunology Research.

Plasticity in the Absence of NOTCH Uncovers a RUNX2-Dependent Pathway in Small Cell Lung Cancer

Kristen L. Jones, Kristen L Jones, M. Tolstorukov, 2021, Cancer Research.

MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer.

C. Paweletz, P. Jänne, J. Köhler, 2022, Cancer cell.

Yeast HOG1 MAP Kinase Cascade Is Regulated by a Multistep Phosphorelay Mechanism in the SLN1–YPD1–SSK1 “Two-Component” Osmosensor

Francesc Posas, Tatsuya Maeda, T. Maeda, 1996, Cell.

Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth.

Travis J Cohoon, J. Mesirov, P. Tamayo, 2014, The Journal of clinical investigation.

3D microfluidic ex vivo culture of organotypic tumor spheroids to model immune checkpoint blockade.

Roger D Kamm, Valeria Chiono, Amir R Aref, 2018, Lab on a chip.

Dynamic single-cell RNA sequencing identifies immunotherapy persister cells following PD-1 blockade.

C. Paweletz, P. Hammerman, P. Lizotte, 2020, The Journal of clinical investigation.

Overcoming Resistance to Dual Innate Immune and MEK Inhibition Downstream of KRAS.

P. Tamayo, R. Neve, Kwok-Kin Wong, 2018, Cancer cell.

Tumor innate immunity primed by specific interferon-stimulated endogenous retroviruses

P. Tamayo, C. Paweletz, Kwok-Kin Wong, 2018, Nature Medicine.

Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids.

Zhi Wei, Hongye Liu, Wei Huang, 2018, Cancer discovery.

STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment.

Jing Wang, G. Freeman, I. Wistuba, 2016, Cancer research.

Distinct functional roles of the two intracellular phosphatase like domains of the receptor‐linked protein tyrosine phosphatases LCA and LAR.

H. Saito, M. Streuli, M Streuli, 1990, The EMBO journal.

Long-term Benefit of PD-L1 Blockade in Lung Cancer Associated with JAK3 Activation

S. Carter, L. Garraway, E. V. Van Allen, 2015, Cancer Immunology Research.

ER Stress Signaling Promotes the Survival of Cancer "Persister Cells" Tolerant to EGFR Tyrosine Kinase Inhibitors.

G. Wei, A. Letai, P. Hammerman, 2018, Cancer research.

The germline factor DDX4 contributes to the chemoresistance of small cell lung cancer cells

D. Barbie, N. Ahsan, N. Tapinos, 2022, bioRxiv.

Tumor-Derived cGAMP Regulates Activation of the Vasculature

C. Paweletz, R. Kamm, V. Chiono, 2020, Frontiers in Immunology.

Phosphorylation of RAB7 by TBK1/IKKε Regulates Innate Immune Signaling in Triple Negative Breast Cancer.

Jacob D. Jaffe, S. Carr, D. Barbie, 2019, Cancer research.

Activation of tumor-cell STING primes NK-cell therapy.

C. Paweletz, M. Tolstorukov, W. Richards, 2022, Cancer immunology research.

The RB–IL-6 axis controls self-renewal and endocrine therapy resistance by fine-tuning mitochondrial activity

M. Ewen, D. Barbie, T. Nishiuchi, 2017, Oncogene.

MicroRNA-140 mediates RB tumor suppressor function to control stem cell-like activity through interleukin-6

D. Barbie, Tomoaki Tanaka, T. Nishiuchi, 2017, Oncotarget.

Structure and ubiquitination-dependent activation of TANK-binding kinase 1.

W. Hahn, S. Ficarro, J. Marto, 2013, Cell reports.

MET-Induced CD73 Restrains STING-Mediated Immunogenicity of EGFR-Mutant Lung Cancer

C. Paweletz, P. Janne, P. Lizotte, 2022, Cancer research.

Isolation and characterization of temperature-sensitive and thermostable mutants of the human receptor-like protein tyrosine phosphatase LAR.

M. Streuli, M. Itoh, M Streuli, 1991, The Journal of biological chemistry.

Electronic profiling of membrane antigen expression via immunomagnetic cell manipulation.

A. F. Sarioglu, C. Paweletz, R. Kamm, 2019, Lab on a chip.

ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer

Z. Szallasi, D. Irvine, D. Keskin, 2023, Nature Cancer.