Mari Ishigami‐Yuasa

发表

Prostaglandin E2 and its receptor EP2 trigger signaling that contributes to YAP‐mediated cell competition

H. Nishina, S. Terai, H. Kagechika, 2020, Genes to cells : devoted to molecular & cellular mechanisms.

Chemical Screening of Nuclear Receptor Modulators

H. Kagechika, Mari Ishigami‐Yuasa, 2020, International journal of molecular sciences.

Activation of β2‐adrenergic receptor signals suppresses mesenchymal phenotypes of oral squamous cell carcinoma cells

H. Harada, H. Kagechika, K. A. Podyma-Inoue, 2020, Cancer science.

Chemical compounds that suppress hypoxia-induced stress granule formation enhance cancer drug sensitivity of human cervical cancer HeLa cells

Y. Hata, H. Kagechika, Mari Ishigami‐Yuasa, 2018, Journal of biochemistry.

Screening with a Novel Cell-Based Assay for TAZ Activators Identifies a Compound That Enhances Myogenesis in C2C12 Cells and Facilitates Muscle Repair in a Muscle Injury Model

Y. Hata, H. Nishina, H. Kagechika, 2014, Molecular and Cellular Biology.

Junichi Injury Model and Facilitates Muscle Repair in a Muscle That Enhances Myogenesis in C 2 C 12 Cells for TAZ Activators Identifies a Compound Screening with a Novel Cell-Based Assay

Y. Hata, H. Nishina, H. Kagechika, 2014 .

Structural Development of Salicylanilide‐Based SPAK Inhibitors as Candidate Antihypertensive Agents

H. Kagechika, S. Uchida, Takayasu Mori, 2021, ChemMedChem.

Structural development of N-(4-phenoxyphenyl)benzamide derivatives as novel SPAK inhibitors blocking WNK kinase signaling.

H. Kagechika, S. Uchida, Takayasu Mori, 2020, Bioorganic & medicinal chemistry letters.

Development of WNK signaling inhibitors as a new class of antihypertensive drugs.

H. Kagechika, S. Uchida, Takayasu Mori, 2017, Bioorganic & medicinal chemistry.

A novel pathway for the production of hydrogen sulfide from D-cysteine in mammalian cells

N. Nagahara, Y. Kimura, Norihiro Shibuya, 2013, Nature Communications.

Structural development of a type-1 ryanodine receptor (RyR1) Ca2+-release channel inhibitor guided by endoplasmic reticulum Ca2+ assay.

H. Kagechika, T. Murayama, T. Sakurai, 2019, European journal of medicinal chemistry.

Efficient high-throughput screening by ER Ca measurement to identify inhibitors of ryanodine receptor Ca-release channels

M. Iino, H. Kagechika, H. Ogawa, 2018 .

Efficient High-Throughput Screening by Endoplasmic Reticulum Ca2+ Measurement to Identify Inhibitors of Ryanodine Receptor Ca2+-Release Channels

M. Iino, H. Kagechika, H. Ogawa, 2018, Molecular Pharmacology.

Drug-Repositioning Screening for Keap1-Nrf2 Binding Inhibitors using Fluorescence Correlation Spectroscopy

Y. Yoshizaki, H. Kagechika, T. Rai, 2017, Scientific Reports.

The mevalonate pathway regulates primitive streak formation via protein farnesylation

H. Nishina, J. Penninger, H. Kagechika, 2016, Scientific Reports.

Development of Androgen-Antagonistic Coumarinamides with a Unique Aromatic Folded Pharmacophore

H. Kagechika, Mari Ishigami‐Yuasa, S. Fujii, 2020, International journal of molecular sciences.

Design and synthesis of 4-benzyl-1-(2H)-phthalazinone derivatives as novel androgen receptor antagonists.

K. Yura, Y. Hashimoto, H. Kagechika, 2015, European journal of medicinal chemistry.

A new cell-based assay to evaluate myogenesis in mouse myoblast C2C12 cells.

Y. Hata, H. Kagechika, Manami Kodaka, 2015, Experimental cell research.

Class IIb HDAC Inhibition Enhances the Inhibitory Effect of Am80, a Synthetic Retinoid, in Prostate Cancer.

H. Kagechika, Mari Ishigami‐Yuasa, H. Ekimoto, 2019, Biological & pharmaceutical bulletin.

Novel YAP1 Activator, Identified by Transcription-Based Functional Screen, Limits Multiple Myeloma Growth

Y. Hata, H. Nishina, H. Kagechika, 2017, Molecular Cancer Research.

Structure-activity relationship of novel (benzoylaminophenoxy)phenol derivatives as anti-prostate cancer agents.

H. Kagechika, Ayumi Yamada, Mari Ishigami‐Yuasa, 2018, Bioorganic & medicinal chemistry.

A cell-based assay to screen stimulators of the Hippo pathway reveals the inhibitory effect of dobutamine on the YAP-dependent gene transcription.

Y. Hata, H. Nishina, Y. Okuno, 2011, Journal of biochemistry.

Chemical library screening for WNK signalling inhibitors using fluorescence correlation spectroscopy.

S. Sasaki, H. Kagechika, T. Rai, 2013, The Biochemical journal.

Validation of chemical compound library screening for transcriptional co‐activator with PDZ‐binding motif inhibitors using GFP‐fused transcriptional co‐activator with PDZ‐binding motif

Y. Hata, H. Nishina, H. Kagechika, 2016, Cancer science.

Identification of selective inhibitors for diffuse-type gastric cancer cells by screening of annotated compounds in preclinical models

Y. Yuasa, Y. Akiyama, H. Kagechika, 2018, British Journal of Cancer.

All trans-retinoic acid analogs promote cancer cell apoptosis through non-genomic Crabp1 mediating ERK1/2 phosphorylation

H. Kagechika, N. Koyano-Nakagawa, Li-Na Wei, 2016, Scientific Reports.

Development of an ‘OFF-ON-OFF’ fluorescent pH sensor suitable for the study of intracellular pH

H. Kagechika, T. Shiraishi, T. Hirano, 2016 .

Discovery of Novel SPAK Inhibitors That Block WNK Kinase Signaling to Cation Chloride Transporters.

S. Sasaki, H. Kagechika, T. Rai, 2015, Journal of the American Society of Nephrology : JASN.

Characterization of a novel compound that promotes myogenesis via Akt and transcriptional co-activator with PDZ-binding motif (TAZ) in mouse C2C12 cells

Y. Hata, H. Nishina, H. Kagechika, 2020, PloS one.

CSE1L promotes nuclear accumulation of transcriptional coactivator TAZ and enhances invasiveness of human cancer cells

Y. Hata, H. Nishina, K. Nakahama, 2021, The Journal of biological chemistry.

Identification of selective inhibitors for diffuse-type gastric cancer cells by screening of annotated compounds in preclinical models

Y. Yuasa, Y. Akiyama, H. Kagechika, 2018, British Journal of Cancer.

A cell-based screening for TAZ activators identifies ethacridine, a widely used antiseptic and abortifacient, as a compound that promotes dephosphorylation of TAZ and inhibits adipogenesis in C3H10T1/2 cells.

Y. Hata, H. Nishina, H. Kagechika, 2015, Journal of biochemistry.

Drug-Repositioning Screening for Keap1-Nrf2 Binding Inhibitors using Fluorescence Correlation Spectroscopy

Y. Yoshizaki, H. Kagechika, T. Rai, 2017, Scientific Reports.

A novel pathway for the production of hydrogen sulfide from D-cysteine in mammalian cells

N. Nagahara, Y. Kimura, Norihiro Shibuya, 2013, Nature Communications.

Y. Hata, H. Nishina, H. Kagechika, 2015, Journal of biochemistry.

Screening for Novel Type 2 Ryanodine Receptor Inhibitors by Endoplasmic Reticulum Ca2+ Monitoring

M. Iino, H. Nishio, H. Kagechika, 2023, Molecular Pharmacology.

A Modified Murine Embryonic Stem Cell Test for Evaluating the Teratogenic Effects of Drugs on Early Embryogenesis

H. Nishina, H. Kagechika, Yoshimi Okamoto-Uchida, 2015, PloS one.

Screening for Novel Type 2 Ryanodine Receptor Inhibitors by Endoplasmic Reticulum Ca 2 1 Monitoring S

M. Iino, H. Kagechika, T. Murayama, 2022 .