Yeeman K. Ramtohul

发表

Bicyclic heteroaryl inhibitors of stearoyl-CoA desaturase: from systemic to liver-targeting inhibitors.

Lei Zhang, Serge Leger, Jean-Philippe Leclerc, 2011, Bioorganic & medicinal chemistry letters.

Development of a liver-targeted stearoyl-CoA desaturase (SCD) inhibitor (MK-8245) to establish a therapeutic window for the treatment of diabetes and dyslipidemia.

David A. Powell, Lei Zhang, R. Oballa, 2011, Journal of medicinal chemistry.

3,4-Diarylpiperidines as potent renin inhibitors.

J. Falgueyret, Yongxin Han, E. Cauchon, 2012, Bioorganic & medicinal chemistry letters.

Conversion of systemically-distributed triazole-based stearoyl-CoA desaturase (SCD) uHTS hits into liver-targeted SCD inhibitors.

J. Falgueyret, R. Oballa, J. Guay, 2011, Bioorganic & medicinal chemistry letters.

Synthesis of pseudoxazolones and their inhibition of the 3C cysteine proteinases from hepatitis A virus and human rhinovirus-14

J. Vederas, M. James, Yeeman K. Ramtohul, 2002 .

Pseudoxazolones, a new class of inhibitors for cysteine proteinases: inhibition of hepatitis A virus and human rhinovirus 3C proteinases

J. Vederas, M. James, Yeeman K. Ramtohul, 2001 .

Thiazole analog as stearoyl-CoA desaturase 1 inhibitor.

J. Guay, C. Li, Yeeman K. Ramtohul, 2009, Bioorganic & medicinal chemistry letters.

SAR and optimization of thiazole analogs as potent stearoyl-CoA desaturase inhibitors.

R. Oballa, J. Guay, Sébastien Guiral, 2010, Bioorganic & medicinal chemistry letters.

2-Aryl benzimidazoles: human SCD1-specific stearoyl coenzyme-A desaturase inhibitors.

J. Falgueyret, R. Oballa, P. Tawa, 2010, Bioorganic & medicinal chemistry letters.

A Multiplexed Cell Assay in HepG2 Cells for the Identification of Delta-5, Delta-6, and Delta-9 Desaturase and Elongase Inhibitors

J. Guay, S. Gagné, A. Styhler, 2010, Journal of biomolecular screening.

Design and synthesis of potent, isoxazole-containing renin inhibitors.

J. Falgueyret, M. Percival, Yongxin Han, 2012, Bioorganic & medicinal chemistry letters.

Oxidative cyclizations in a nonpolar solvent using molecular oxygen and studies on the stereochemistry of oxypalladation.

B. Stoltz, Yeeman K. Ramtohul, Raissa M. Trend, 2005, Journal of the American Chemical Society.

Palladium-catalyzed oxidative wacker cyclizations in nonpolar organic solvents with molecular oxygen: a stepping stone to asymmetric aerobic cyclizations.

B. Stoltz, Yeeman K. Ramtohul, E. M. Ferreira, 2003, Angewandte Chemie.

Synthesis and evaluation of keto-glutamine analogues as inhibitors of hepatitis A virus 3C proteinase.

J. Vederas, M. James, Yeeman K. Ramtohul, 2002, The Journal of organic chemistry.

Synthesis and Evaluation of Keto-Glutamine Analogues as Inhibitors of Hepatitis A Virus 3 C Proteinase

J. Vederas, M. James, Yeeman K. Ramtohul, 2022 .

Serine and threonine beta-lactones: a new class of hepatitis A virus 3C cysteine proteinase inhibitors.

J. Vederas, M. James, Michael N G James, 2002, The Journal of organic chemistry.

Direct C-Arylation of β-Enamino Esters and Ketones with Arynes

Yeeman K. Ramtohul, Anik Chartrand, 2007 .

Restoring Methicillin-Resistant Staphylococcus aureus Susceptibility to β-Lactam Antibiotics

Eric Langlois, Alexandre Caron, Mihai Petcu, 2012, Science Translational Medicine.

Pd-catalyzed enantioselective aerobic oxidation of secondary alcohols: applications to the total synthesis of alkaloids.

B. Stoltz, Shyam Krishnan, Yeeman K. Ramtohul, 2008, Journal of the American Chemical Society.

ChemInform Abstract: Serine and Threonine β-Lactones: A New Class of Hepatitis A Virus 3C Cysteine Proteinase Inhibitors.

J. Vederas, M. James, Yeeman K. Ramtohul, 2002 .

Synthesis of Polycyclic Indolone and Pyrroloindolone Heterocycles via the Annulation of Indole- and Pyrrole-2-carboxylate Esters with Arynes.

Yeeman K. Ramtohul, Robert D. Giacometti, 2009 .

Discovery of potent and liver-targeted stearoyl-CoA desaturase (SCD) inhibitors in a bispyrrolidine series.

R. Oballa, S. Léger, Sébastien Guiral, 2012, Bioorganic & medicinal chemistry letters.

5-(Trifluoromethyl)pyrazoles by a Regioselective [3+2] Cycloaddition

Yeeman K. Ramtohul, Mark Reed, 2021, Synfacts.

A Multiplexed Cell Assay in HepG2 Cells for the Identification of Delta-5, Delta-6, and Delta-9 Desaturase and Elongase Inhibitors

J. Guay, S. Gagné, A. Styhler, 2010, Journal of biomolecular screening.