M Leost

Structure-based design modifications of the paullone molecular scaffold for cyclin-dependent kinase inhibition.

L Meijer, N Pattabiraman, R Gussio, 2000, Anti-cancer drug design.

2-Substituted paullones: CDK1/cyclin B-inhibiting property and in vitro antiproliferative activity.

L Meijer, R Gussio, D W Zaharevitz, 2000, Bioorganic & medicinal chemistry letters.

Discovery and initial characterization of the paullones, a novel class of small-molecule inhibitors of cyclin-dependent kinases.

L Meijer, D W Zaharevitz, L. Meijer, 1999, Cancer research.

Paullones are potent inhibitors of glycogen synthase kinase-3beta and cyclin-dependent kinase 5/p25.

G L Snyder, L Meijer, D W Zaharevitz, 2000, European journal of biochemistry.

Properties and potential-applications of chemical inhibitors of cyclin-dependent kinases.

L Meijer, L. Meijer, M. Leost, 1999, Pharmacology & therapeutics.