Harvey J. Clewell

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Harmonization: Developing Consistent Guidelines for Applying Mode of Action and Dosimetry Information to Cancer and Noncancer Risk Assessment

Hugh A. Barton, Melvin E. Andersen, Harvey J. Clewell, 1998 .

Evaporation and Groundfall of JP-4 Jet Fuel Jettisoned by USAF Aircraft

Harvey J. Clewell, 1980 .

Proceedings of the Conference on Toxicology: Applications of Advances in Toxicology to Risk Assessment. Held at Wright-Patterson AFB, Ohio on 19-21 May 1992

Harvey J. Clewell, Darol E. Dodd, David R Mattie, 1993 .

Physiologically based pharmacokinetic modeling software

Andreas Schepky, Harvey J. Clewell, C. E. Hack, 2020 .

Population Life-course exposure to health effects model (PLETHEM): An R package for PBPK modeling

Harvey J. Clewell, Patrick D. McMullen, Miyoung Yoon, 2020 .

An integrated health risk assessment of contaminated sites under aleatory and epistemic uncertainties

Harvey J. Clewell, Hua Li, Gopal Achari, 2011 .

Incorporating New Technologies Into Toxicity Testing and Risk Assessment: Moving From 21st Century Vision to a Data-Driven Framework

Melvin E. Andersen, Harvey J. Clewell, Russell S. Thomas, 2013, Toxicological sciences : an official journal of the Society of Toxicology.

Application of Physiologically Based Pharmacokinetic Modeling in Health Risk Assessment

Harvey J. Clewell, 2010 .

Improving Risk Assessment: Research Opportunities in Dose Response Modeling to Improve Risk Assessment

David B. Dunson, Harvey J. Clewell, A. John Bailer, 2002 .

Issues Surrounding Comparative Risk Assessments of Operational Materials: An Example with Air Force Hydraulic Fluids,

Melvin E. Andersen, Harvey J. Clewell, David R Mattie, 1993 .

A Multiple Dose-Route Physiological Pharmacokinetic Model for Volatile Chemicals Using ACSL/PC,

Melvin E. Andersen, Harvey J. Clewell, 1986 .

CHAPTER 11:Big Data and Biokinetics

Harvey J. Clewell, Bas J. Blaauboer, Miyoung Yoon, 2019 .

CHAPTER 17:Systems Pharmacology Modeling

Hugh A. Barton, Harvey J. Clewell, Miyoung Yoon, 2015 .

Conference on chemical risk assessment in the Department of Defense (DoD) : science, policy, and practice

Harvey J. Clewell, 1992 .

The TTC Data Mart: An interactive browser for threshold of toxicological concern calculations

Melvin E. Andersen, Harvey J. Clewell, Patrick D. McMullen, 2020 .

Improving the Development and Use of Biologically Based Dose Response Models (BBDR) in Risk Assessment

Harvey J. Clewell, R. Woodrow Setzer, Robert S. DeWoskin, 2001 .

Combining transcriptomics and PBPK modeling indicates a primary role of hypoxia and altered circadian signaling in dichloromethane carcinogenicity in mouse lung and liver

Melvin E. Andersen, Harvey J. Clewell, Michael B. Black, 2017, Toxicology and Applied Pharmacology.

Integrating pathway-based transcriptomic data into quantitative chemical risk assessment: a five chemical case study.

Melvin E. Andersen, Harvey J. Clewell, Longlong Yang, 2012, Mutation research.

PBPK Model for Atrazine and Its Chlorotriazine Metabolites in Rat and Human

Melvin E. Andersen, Harvey J. Clewell, Timothy P. Pastoor, 2016, Toxicological sciences : an official journal of the Society of Toxicology.

Bayesian Calibration of a Physiologically Based Pharmacokinetic/Pharmacodynamic Model of Carbaryl Cholinesterase Inhibition

Harvey J. Clewell, Yu-Mei Tan, Andy Nong, 2008, Journal of toxicology and environmental health. Part A.

An Analysis of N-Acetylcysteine Treatment for Acetaminophen Overdose Using a Systems Model of Drug-Induced Liver Injury

Melvin E. Andersen, Harvey J. Clewell, Brett A. Howell, 2012, Journal of Pharmacology and Experimental Therapeutics.

Temporal concordance between apical and transcriptional points of departure for chemical risk assessment.

Melvin E. Andersen, Harvey J. Clewell, Michael B. Black, 2013, Toxicological sciences : an official journal of the Society of Toxicology.

Addressing Early Life Sensitivity Using Physiologically Based Pharmacokinetic Modeling and In Vitro to In Vivo Extrapolation

Harvey J. Clewell, Miyoung Yoon, H. Clewell, 2016, Toxicological research.

Kinetics of Water Vapor Sorption in Stratum Corneum

Harvey J. Clewell, James N. McDougal, Z. Liron, 1994 .

Determination of a site-specific reference dose for methylmercury for fish-eating populations

Harvey J. Clewell, Greg Lawrence, Cynthia Van Landingham, 2000 .

High-throughput in-silico prediction of ionization equilibria for pharmacokinetic modeling.

Harvey J. Clewell, Kamel Mansouri, John F. Wambaugh, 2018, The Science of the total environment.

Physiologically Based Pharmacokinetic (PBPK) Modeling of Interstrain Variability in Trichloroethylene Metabolism in the Mouse

Harvey J. Clewell, Fred A. Wright, Weihsueh A. Chiu, 2014, Environmental health perspectives.

Introduction: A Historical Perspective of the Development and Applications of PBPK Models

Melvin E. Andersen, Harvey J. Clewell, Raymond S. H. Yang, 2005 .

Chemical Risk Analysis: A Practical Handbook

Harvey J. Clewell, H. Clewell, 2002 .

Applying Mode-of-Action and Pharmacokinetic Considerations in Contemporary Cancer Risk Assessments: An Example with Trichloroethylene

Melvin E. Andersen, Harvey J. Clewell, M. Andersen, 2004 .

Data for Physiologically Based Pharmacokinetic Modeling in Neonatal Animals: Physiological Parameters in Mice and Sprague-Dawley Rats

Hugh A. Barton, Harvey J. Clewell, Tammie R. Covington, 2004 .

Application of Physiological Computational Fluid Dynamics Models to Predict Interspecies Nasal Dosimetry of Inhaled Acrolein

Harvey J. Clewell, David C. Dorman, Jeffry D. Schroeter, 2008 .

Physiologically Based Pharmacokinetic Modeling : Science and Applications

Melvin E. Andersen, Harvey J. Clewell, Raymond S. H. Yang, 2005 .

Review and Evaluation of the Potential Impact of Age- and Gender-Specific Pharmacokinetic Differences on Tissue Dosimetry

Harvey J. Clewell, Greg Lawrence, Justin Teeguarden, 2002, Critical reviews in toxicology.

Physiologically based pharmacokinetic and pharmacodynamic model for the inhibition of acetylcholinesterase by diisopropyfluorophosphate

Melvin E. Andersen, Harvey J. Clewell, Jeffery M. Gearhart, 1990 .

Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing

Melvin E. Andersen, Harvey J. Clewell, Barbara A. Wetmore, 2015, Toxicological sciences : an official journal of the Society of Toxicology.

A Semiphysiologically Based Pharmacokinetic Modeling Approach to Predict the Dose-Exposure Relationship of an Antiparasitic Prodrug/Active Metabolite Pair

Harvey J. Clewell, Miyoung Yoon, Kim L. R. Brouwer, 2012, Drug Metabolism and Disposition.

Food for Thought ... Can Case Study Approaches Speed Implementation of the NRC Report : “ Toxicity Testing in the 21 st Century : A Vision and a Strategy ? ”

Melvin E. Andersen, Harvey J. Clewell, Paul L. Carmichael, 2011 .

Cross-species transcriptomic analysis of mouse and rat lung exposed to chloroprene.

Melvin E. Andersen, Harvey J. Clewell, Michael B. Black, 2013, Toxicological sciences : an official journal of the Society of Toxicology.

Preclinical Development Handbook: ADME and Biopharmaceutical Properties

Melvin E. Andersen, Harvey J. Clewell, Thierry Lavé, 2007 .

Molecular Signaling Network Motifs Provide a Mechanistic Basis for Cellular Threshold Responses

Melvin E. Andersen, Harvey J. Clewell, Sudin Bhattacharya, 2014, Environmental health perspectives.

Incorporating population variability and susceptible subpopulations into dosimetry for high-throughput toxicity testing.

Harvey J. Clewell, Barbara A. Wetmore, John F. Wambaugh, 2014, Toxicological sciences : an official journal of the Society of Toxicology.

Gas Uptake Inhalation Techniques and the Rates of Metabolism of Chloromethanes, Chloroethanes, and Chloroethylenes in the Rat

Melvin E. Andersen, Harvey J. Clewell, M. Andersen, 1990 .

Associations of Perfluoroalkyl Substances (PFAS) with Lower Birth Weight: An Evaluation of Potential Confounding by Glomerular Filtration Rate Using a Physiologically Based Pharmacokinetic Model (PBPK)

Melvin E. Andersen, Harvey J. Clewell, Miyoung Yoon, 2015, Environmental health perspectives.

In vitro metabolism of di(2-ethylhexyl) phthalate (DEHP) by various tissues and cytochrome P450s of human and rat.

Melvin E. Andersen, Harvey J. Clewell, Rebecca A. Clewell, 2012, Toxicology in vitro : an international journal published in association with BIBRA.

Physiologically Based Pharmacokinetic Modeling

Melvin E. Andersen, Harvey J. Clewell, Thierry Lavé, 2010 .

In vitro to in vivo extrapolation and species response comparisons for drug-induced liver injury (DILI) using DILIsym™: a mechanistic, mathematical model of DILI

Melvin E. Andersen, Harvey J. Clewell, Brett A. Howell, 2012, Journal of Pharmacokinetics and Pharmacodynamics.

Evaluation of the Uncertainty in an Oral Reference Dose for Methylmercury Due to Interindividual Variability in Pharmacokinetics

Harvey J. Clewell, Jeffery M. Gearhart, Tammie R. Covington, 1999, Risk analysis : an official publication of the Society for Risk Analysis.