S. Mallya

发表

Toxoplasma gondii Dysregulates Barrier Function and Mechanotransduction Signaling in Human Endothelial Cells

S. Sureshchandra, I. Messaoudi, M. Lodoen, 2020, mSphere.

Toxoplasma gondii activates a Syk-CARD9-NF-κB signaling axis and gasdermin D-independent release of IL-1β during infection of primary human monocytes

M. Lodoen, William Pandori, S. Mallya, 2019, PLoS pathogens.

Resistance to mTOR Kinase Inhibitors in Lymphoma Cells Lacking 4EBP1

D. Fruman, M. R. Janes, S. Mallya, 2014, PloS one.

kinase inhibitors synergize with histone deacetylase inhibitors to kill B-cell acute leukemia cells.

Lu, M. Konopleva, D. Fruman, 2015 .

Targeting eIF4F translation complex sensitizes B-ALL cells to tyrosine kinase inhibition

D. Fruman, Thanh-Trang T. Vo, S. Mallya, 2021, Scientific Reports.

Efficacy of a Novel Bi-Steric mTORC1 Inhibitor in Models of B-Cell Acute Lymphoblastic Leukemia

Mallika Singh, Edward G. Lorenzana, D. Fruman, 2021, Frontiers in Oncology.

Inhibition of mTOR induces chemoresistance in B-cell acute lymphoblastic leukemia

M. Konopleva, Mengrou Lu, D. Fruman, 2017 .

mTOR inhibition enhances efficacy of dasatinib in ABL-rearranged Ph-like B-ALL

M. Konopleva, D. Fruman, Thanh-Trang T. Vo, 2018, Oncotarget.

The Selective Phosphoinoside-3-Kinase p110δ Inhibitor IPI-3063 Potently Suppresses B Cell Survival, Proliferation, and Differentiation

J. Kutok, D. Fruman, S. Mallya, 2017, Front. Immunol..

Reduced eIF4E function impairs B-cell leukemia without altering normal B-lymphocyte function

D. Fruman, D. Ruggero, S. Mallya, 2021, iScience.

in blood cancers.

A. Letai, L. Lam, Jonathan, 2019 .

Unique role for caspase-8 in the release of IL-1β and active caspase-1 from viable human monocytes during Toxoplasma gondii infection

M. Lodoen, William Pandori, S. Mallya, 2022, bioRxiv.

Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor

Jing Chen, Marina Konopleva, Yi Liu, 2010, Nature Medicine.

Toxoplasma gondii Extends the Life Span of Infected Human Neutrophils by Inducing Cytosolic PCNA and Blocking Activation of Apoptotic Caspases

I. Messaoudi, M. Lodoen, S. Mallya, 2021, mBio.

Effects of Novel Isoform-Selective Phosphoinositide 3-Kinase Inhibitors on Natural Killer Cell Function

D. Fruman, Jongdae Lee, S. Malarkannan, 2014, PloS one.

Efficacy of the investigational mTOR kinase inhibitor MLN0128/INK128 in models of B-cell acute lymphoblastic leukemia

C. Rommel, D. Fruman, M. Lilly, 2013, Leukemia.

Statins enhance efficacy of venetoclax in blood cancers

Angela G. Fleischman, A. Letai, L. Lam, 2018, Science Translational Medicine.

Targeting eIF4F translation initiation complex with SBI-756 sensitises B lymphoma cells to venetoclax

M. Jackson, D. Fruman, Z. Ronai, 2020, British Journal of Cancer.

The 4E-BP–eIF4E axis promotes rapamycin-sensitive growth and proliferation in lymphocytes

N. Sonenberg, D. Fruman, Jongdae Lee, 2016, Science Signaling.

mTORC1 Inhibition Induces Resistance to Methotrexate and 6-Mercaptopurine in Ph+ and Ph-like B-ALL

M. Konopleva, Mengrou Lu, D. Fruman, 2017, Molecular Cancer Therapeutics.

Abstract A49: Inhibition of mTOR induces chemoresistance in B-cell acute lymphoblastic leukemia

Mengrou Lu, D. Fruman, Thanh-Trang T. Vo, 2015 .

mTOR kinase inhibitors synergize with histone deacetylase inhibitors to kill B-cell acute lymphoblastic leukemia cells

M. Konopleva, Mengrou Lu, D. Fruman, 2014, Oncotarget.

A spatially resolved single-cell genomic atlas of the adult human breast

K. Kessenbrock, Kevin Nee, C. Nagi, 2023, Nature.