Jayendra Z. Patel

发表

Comparative molecular field analysis and molecular dynamics studies of α/β hydrolase domain containing 6 (ABHD6) inhibitors

Antti Poso, Tuomo Laitinen, Agnieszka A. Kaczor, 2015, Journal of Molecular Modeling.

New in vitro tools to study human constitutive androstane receptor (CAR) biology: discovery and comparison of human CAR inverse agonists.

A. Poso, W. Sippl, T. Laitinen, 2011, Molecular pharmaceutics.

Chiral 1,3,4-oxadiazol-2-ones as highly selective FAAH inhibitors.

J. Leppänen, A. Poso, T. Laitinen, 2013, Journal of medicinal chemistry.

Biochemical and Pharmacological Characterization of the Human Lymphocyte Antigen B-Associated Transcript 5 (BAT5/ABHD16A)

T. Laitinen, J. Laitinen, T. Nevalainen, 2014, PloS one.

Synthesis and in vitro antibacterial activities of novel oxazolidinones.

B. Srivastava, Bhupendra Mishra, H. Patel, 2008, European journal of medicinal chemistry.

Synthesis and in vitro antibacterial activity of novel methylamino piperidinyl oxazolidinones.

B. Srivastava, Bhupendra Mishra, Jayendra Z. Patel, 2007, Bioorganic & medicinal chemistry letters.

Utilizing PET and MALDI Imaging for Discovery of a Targeted Probe for Brain Endocannabinoid α/β-Hydrolase Domain 6 (ABHD6).

W. Vanduffel, G. Bormans, G. Cowin, 2022, Journal of medicinal chemistry.

Diaryl dihydropyrazole-3-carboxamides with significant in vivo antiobesity activity related to CB1 receptor antagonism: synthesis, biological evaluation, and molecular modeling in the homology model.

Bhupendra Mishra, B. Pandey, Bhupendra Mishra, 2007, Journal of medicinal chemistry.

Hair growth stimulator property of thienyl substituted pyrazole carboxamide derivatives as a CB1 receptor antagonist with in vivo antiobesity effect.

P. Mitra, Bhupendra Mishra, H. Patel, 2009, Bioorganic & medicinal chemistry letters.

Facile synthesis, ex-vivo and in vitro screening of 3-sulfonamide derivative of 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid piperidin-1-ylamide (SR141716) a potent CB1 receptor antagonist.

P. Mitra, Jayendra Z. Patel, Mukul R Jain, 2008, Bioorganic & medicinal chemistry letters.

Strategies to Prevent Biofilm Infections on Biomaterials: Effect of Novel Naturally-Derived Biofilm Inhibitors on a Competitive Colonization Model of Titanium by Staphylococcus aureus and Human Cells

J. Yli-Kauhaluoma, A. Fallarero, K. Savijoki, 2019 .

Repurposing the Sphingosine-1-Phosphate Receptor Modulator Etrasimod as an Antibacterial Agent Against Gram-Positive Bacteria

J. Yli-Kauhaluoma, A. Fallarero, K. Savijoki, 2022, Frontiers in Microbiology.

Food-Grade Bacteria Combat Pathogens by Blocking AHL-Mediated Quorum Sensing and Biofilm Formation

I. Miettinen, P. Varmanen, J. Yli-Kauhaluoma, 2022, Foods.

Chloroquine fumardiamides as novel quorum sensing inhibitors.

J. Yli-Kauhaluoma, A. Fallarero, K. Savijoki, 2020, Bioorganic & medicinal chemistry letters.

Bioisosteric replacement of dihydropyrazole of 4S-(-)-3-(4-chlorophenyl)-N-methyl-N'-[(4-chlorophenyl)-sulfonyl]-4-phenyl-4,5-dihydro-1H-pyrazole-1-caboxamidine (SLV-319) a potent CB1 receptor antagonist by imidazole and oxazole.

P. Mitra, Bhupendra Mishra, Jayendra Z. Patel, 2008, Bioorganic & medicinal chemistry letters.

Identification of Novel Quorum Sensing Inhibitors

Jayendrakumar Zaverbhai Patel, Malena Skogman, Adyary Fallarero Linares, 2017 .

Chemoproteomic, biochemical and pharmacological approaches in the discovery of inhibitors targeting human α/β-hydrolase domain containing 11 (ABHD11).

T. Laitinen, J. Laitinen, T. Nevalainen, 2016, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

1,3,4-Oxadiazol-2-ones as fatty-acid amide hydrolase and monoacylglycerol lipase inhibitors: Synthesis, in vitro evaluation and insight into potency and selectivity determinants by molecular modelling.

A. Poso, M. Lahtela-Kakkonen, T. Nevalainen, 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Revisiting 1,3,4-Oxadiazol-2-ones: Utilization in the Development of ABHD6 Inhibitors.

T. Laitinen, J. Laitinen, T. Nevalainen, 2015, Bioorganic & medicinal chemistry.

Loratadine analogues as MAGL inhibitors.

Tuomo Laitinen, T. Laitinen, J. Laitinen, 2015, Bioorganic & medicinal chemistry letters.

Optimization of 1,2,5‐Thiadiazole Carbamates as Potent and Selective ABHD6 Inhibitors

F. Maxfield, T. Laitinen, R. Runyon, 2015, ChemMedChem.

Docking-Based 3D-QSAR Studies for 1,3,4-oxadiazol-2-one Derivatives as FAAH Inhibitors

A. Poso, T. Laitinen, A. Kaczor, 2021, International journal of molecular sciences.

Combined Effect of Naturally-Derived Biofilm Inhibitors and Differentiated HL-60 Cells in the Prevention of Staphylococcus aureus Biofilm Formation

J. Yli-Kauhaluoma, A. Fallarero, S. Zaat, 2020, Microorganisms.

Synthesis and Biological Evaluation of Fingolimod Derivatives as Antibacterial Agents

J. Yli-Kauhaluoma, A. Fallarero, K. Savijoki, 2021, ACS omega.

Piperazine and piperidine carboxamides and carbamates as inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL).

T. Laitinen, J. Laitinen, T. Nevalainen, 2014, Bioorganic & medicinal chemistry.

Strategies to Prevent Biofilm Infections on Biomaterials: Effect of Novel Naturally-Derived Biofilm Inhibitors on a Competitive Colonization Model of Titanium by Staphylococcus aureus and SaOS-2 Cells

J. Yli-Kauhaluoma, A. Fallarero, K. Savijoki, 2020, Microorganisms.

Bhupendra Mishra, Jayendra Z. Patel, Mukul R Jain, 2008, Bioorganic & Medicinal Chemistry Letters.

Design and synthesis of etrasimod derivatives as potent antibacterial agents against Gram-positive bacteria.

J. Yli-Kauhaluoma, A. Fallarero, Jayendra Z. Patel, 2023, European journal of medicinal chemistry.