M. Heitmeier

发表

Lactotrehalose, an Analog of Trehalose, Increases Energy Metabolism Without Promoting Clostridioides difficile Infection in Mice.

J. Crowley, P. Hruz, K. Shankar, 2019, Gastroenterology.

Pancreatic β-Cell Damage Mediated by β-Cell Production of Interleukin-1

J. Corbett, M. Heitmeier, M. Arnush, 2001, The Journal of Biological Chemistry.

A mouse model of Townes-Brocks syndrome expressing a truncated mutant Sall1 protein is protected from acute kidney injury.

R. Nishinakamura, T. El-Achkar, M. Rauchman, 2015, American journal of physiology. Renal physiology.

Tamm-Horsfall protein-deficient thick ascending limbs promote injury to neighboring S3 segments in an MIP-2-dependent mechanism.

Z. Al-Aly, Xue-Ru Wu, P. Dagher, 2011, American journal of physiology. Renal physiology.

Tamm-Horsfall protein translocates to the basolateral domain of thick ascending limbs, interstitium, and circulation during recovery from acute kidney injury.

Xue-Ru Wu, J. Ryerse, T. El-Achkar, 2013, American journal of physiology. Renal physiology.

Mechanisms of β-cell death in response to double-stranded (ds) RNA and interferon-γ dsrna-dependent protein kinase apoptosis and nitric oxide-dependent necrosis

D. Scheuner, R. Kaufman, J. Corbett, 2001 .

Actions of 1 5D e o x y-1 2 , 1 4-Prostaglandin J 2 and Tr o g l

J. Corbett, L. Maggi, H. Sadeghi, 2000 .

Double-stranded RNA Inhibits β-Cell Function and Induces Islet Damage by Stimulating β-Cell Production of Nitric Oxide*

J. Corbett, M. Heitmeier, A. Scarim, 1999, The Journal of Biological Chemistry.

IL-1 produced and released endogenously within human islets inhibits beta cell function.

J. Corbett, M. Heitmeier, M. Arnush, 1998, The Journal of clinical investigation.

Potential role of PKR in double‐stranded RNA‐induced macrophage activation

D. Scheuner, R. Kaufman, J. Corbett, 2000, The EMBO journal.

Potential role of resident islet macrophage activation in the initiation of autoimmune diabetes.

J. Corbett, C. B. Kelly, M. Heitmeier, 1998, Journal of immunology.

Prolonged STAT1 Activation Is Associated with Interferon-γ Priming for Interleukin-1-induced Inducible Nitric-oxide Synthase Expression by Islets of Langerhans*

J. Corbett, M. Heitmeier, A. Scarim, 1999, The Journal of Biological Chemistry.

Interferon-γ Increases the Sensitivity of Islets of Langerhans for Inducible Nitric-oxide Synthase Expression Induced by Interleukin 1*

J. Corbett, M. Heitmeier, A. Scarim, 1997, The Journal of Biological Chemistry.

Role of Cyclooxygenase-2 in Cytokine-induced β-Cell Dysfunction and Damage by Isolated Rat and Human Islets*

J. Corbett, C. B. Kelly, M. Heitmeier, 2004, Journal of Biological Chemistry.

Anti-inflammatory actions of 15-deoxy-delta 12,14-prostaglandin J2 and troglitazone: evidence for heat shock-dependent and -independent inhibition of cytokine-induced inducible nitric oxide synthase expression.

J. Corbett, L. Maggi, H. Sadeghi, 2000, Diabetes.

CALL FOR PAPERS Pathophysiology of Acute Kidney Injury Tamm-Horsfall protein translocates to the basolateral domain of thick ascending limbs, interstitium, and circulation during recovery from acute kidney injury

J. Ryerse, T. El-Achkar, M. Heitmeier, 2013 .

Double-stranded RNA-induced Inducible Nitric-oxide Synthase Expression and Interleukin-1 Release by Murine Macrophages Requires NF-κB Activation*

J. Corbett, M. Heitmeier, A. Scarim, 1998, The Journal of Biological Chemistry.

Irreversible inhibition of metabolic function and islet destruction after a 36-hour exposure to interleukin-1beta.

J. Corbett, M. Heitmeier, A. Scarim, 1997, Endocrinology.

Metabolic and Cardiac Adaptation to Chronic Pharmacologic Blockade of Facilitative Glucose Transport in Murine Dilated Cardiomyopathy and Myocardial Ischemia

P. Hruz, R. Hresko, M. Payne, 2018, Scientific Reports.

Double-stranded RNA-induced inducible nitric-oxide synthase expression and interleukin-1 release by murine macrophages requires NF-kappaB activation.

J. Corbett, M. Heitmeier, A. Scarim, 1998, The Journal of biological chemistry.

Pancreatic beta-cell damage mediated by beta-cell production of interleukin-1. A novel mechanism for virus-induced diabetes.

J. Corbett, M. Heitmeier, M. Arnush, 2001, The Journal of biological chemistry.

Mechanisms of beta-cell death in response to double-stranded (ds) RNA and interferon-gamma: dsRNA-dependent protein kinase apoptosis and nitric oxide-dependent necrosis.

D. Scheuner, R. Kaufman, J. Corbett, 2001, The American journal of pathology.

Controlling the intracellular localization of fluorescent polyamide analogues in cultured cells.

J. Bashkin, B. Schweitzer, M. Heitmeier, 2003, Bioorganic & medicinal chemistry letters.

The Role of Tumor Necrosis Factor Alpha in Regulating the Expression of Tamm-Horsfall Protein (Uromodulin) in Thick Ascending Limbs during Kidney Injury

T. El-Achkar, M. Heitmeier, R. Micanovic, 2014, American Journal of Nephrology.

The Glucose Transporter PfHT1 Is an Antimalarial Target of the HIV Protease Inhibitor Lopinavir

Christopher M. Armstrong, P. Hruz, M. Heitmeier, 2015, Antimicrobial Agents and Chemotherapy.

Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis

J. Crowley, K. Yarasheski, N. Davidson, 2016, Science Signaling.

Cytotoxic Role of Nitric Oxide in Diabetes

J. Corbett, M. Heitmeier, 2000 .

Development of GLUT4-selective antagonists for multiple myeloma therapy.

P. Hruz, A. Nooka, M. Heitmeier, 2017, European journal of medicinal chemistry.

Double-stranded RNA-dependent protein kinase is not required for double-stranded RNA-induced nitric oxide synthase expression or nuclear factor-kappaB activation by islets.

J. Corbett, L. Maggi, M. Heitmeier, 2001, Diabetes.

Identification of druggable small molecule antagonists of the Plasmodium falciparum hexose transporter PfHT and assessment of ligand access to the glucose permeation pathway via FLAG-mediated protein engineering

P. Hruz, Rachel L. Edwards, R. Hresko, 2019, PloS one.

SLC2A8 (GLUT8) is a mammalian trehalose transporter required for trehalose-induced autophagy

J. Crowley, K. Yarasheski, P. Hruz, 2016, Scientific Reports.

Muscle-Specific Ablation of Glucose Transporter 1 (GLUT1) Does Not Impair Basal or Overload-Stimulated Skeletal Muscle Glucose Uptake

P. Hruz, T. Nemirovskaya, E. Abel, 2022, Biomolecules.

Heat Shock Inhibits Cytokine-Induced Nitric Oxide Synthase Expression by Rat and Human Islets* * This work was supported by research grants from the NIH (DK-52194) and The Tobacco Research Council.

J. Corbett, M. Heitmeier, A. Scarim, 1998, Endocrinology.

Irreversible Inhibition of Metabolic Function and Islet Destruction after a 36-Hour Exposure to Interleukin-1β.

J. Corbett, M. Heitmeier, A. Scarim, 1997, Endocrinology.

A novel FRET-based screen in high-throughput format to identify inhibitors of malarial and human glucose transporters

David D. Thomas, P. Hruz, Rachel L. Edwards, 2018 .

A novel FRET-based screen in high-throughput format to identify inhibitors of malarial and human glucose transporters

P. Hruz, Rachel L. Edwards, M. Heitmeier, 2018 .

Heat Shock Inhibits Cytokine-Induced Nitric Oxide Synthase Expression by Rat and Human Islets* * This work was supported by research grants from the NIH (DK-52194) and The Tobacco Research Council.

J. Corbett, M. Heitmeier, A. Scarim, 1998, Endocrinology.

A formulation-enabled preclinical efficacy assessment of a farnesoid X receptor agonist, GW4064, in hamsters and cynomolgus monkeys.

D. Thompson, Sarbani Ghosh, Po‐Chang Chiang, 2011, Journal of pharmaceutical sciences.

In Silico Modeling-based Identification of Glucose Transporter 4 (GLUT4)-selective Inhibitors for Cancer Therapy*

P. Hruz, A. Nooka, S. Rosen, 2015, The Journal of Biological Chemistry.

A Novel Fluorescence Resonance Energy Transfer-Based Screen in High-Throughput Format To Identify Inhibitors of Malarial and Human Glucose Transporters

David D. Thomas, P. Hruz, Rachel L. Edwards, 2016, Antimicrobial Agents and Chemotherapy.

Heat Shock Inhibits Cytokine-Induced Nitric Oxide Synthase Expression by Rat and Human Islets* * This work was supported by research grants from the NIH (DK-52194) and The Tobacco Research Council.

M. Heitmeier, A. Scarim, J. A. Corbett, 1998, Endocrinology.

Double-stranded RNA-dependent protein kinase is not required for double-stranded RNA-induced nitric oxide synthase expression or nuclear factor-kappaB activation by islets.

J. Corbett, L. Maggi, M. Heitmeier, 2001, Diabetes.