J. Salata

发表

Species variants of the IsK protein: differences in kinetics, voltage dependence, and La3+ block of the currents expressed in Xenopus oocytes

M. Sanguinetti, Jeffrey S. Smith, R. Swanson, 2004, Pflügers Archiv.

Functional and pharmacological properties of canine ERG potassium channels.

Hao Wang, Jerzy Karczewski, Paul B Bennett, 2003, American journal of physiology. Heart and circulatory physiology.

Saxitoxin Is a Gating Modifier of hERG K+ Channels

P. Bennett, J. Salata, Jixin Wang, 2003, The Journal of general physiology.

The hERG channel and risk of drug-acquired cardiac arrhythmia: an overview.

J. Salata, E. Trepakova, A. Lagrutta, 2008, Current topics in medicinal chemistry.

A Model for Early Afterdepolarizations: Induction With the Ca2+ Channel Agonist Bay K 8644

C. January, J. Riddle, C T January, 1988, Circulation research.

Kv1.5 Potassium Channel Inhibitors for the Treatment and Prevention of Atrial Fibrillation

L. Kiss, J. Salata, A. Lagrutta, 2008 .

Increasing I(Ks) corrects abnormal repolarization in rabbit models of acquired LQT2 and ventricular hypertrophy.

P. Kowey, Xiaoping Xu, G. Yan, 2002, American journal of physiology. Heart and circulatory physiology.

Cardiac electrophysiologic and antiarrhythmic actions of two long-acting spirobenzopyran piperidine class III agents, L-702,958 and L-706,000 [MK-499].

M. Sanguinetti, R. Stein, J. Lynch, 1994, The Journal of pharmacology and experimental therapeutics.

Improved throughput of PatchXpress hERG assay using intracellular potassium fluoride.

Spencer J. Dech, Bharath Balasubramanian, F. Kinose, 2008, Assay and drug development technologies.

Kinesin spindle protein (KSP) inhibitors. Part 7: Design and synthesis of 3,3-disubstituted dihydropyrazolobenzoxazines as potent inhibitors of the mitotic kinesin KSP.

Youwei Yan, P. Coleman, L. Kuo, 2007, Bioorganic & medicinal chemistry letters.

Functional expression of L- and T-type Ca2+ channels in murine HL-1 cells.

M. Xia, H. A. Liang, J. Salata, 2004, Journal of molecular and cellular cardiology.

A Model for Early Afterdepolarizations: Induction With the Ca 2+ Channel Agonist

Joseph J. Salata, Craig T. January, C. January, 2011 .

Parasympathetic Innervation of the Heart: Acetylcholine Turnover in Vivo

J. Salata, O. M. Brown, L. Graziani, 1986 .

In vivo acetylcholine turnover in rat heart.

J. Salata, O. M. Brown, 1983, Life sciences.

MK-0448, a Specific Kv1.5 Inhibitor: Safety, Pharmacokinetics, and Pharmacodynamic Electrophysiology in Experimental Animal Models and Humans

W. Kraft, H. Greenberg, C. Regan, 2012, Circulation. Arrhythmia and electrophysiology.

Halide ion effects on human Ether-à-go-go related gene potassium channel properties.

Bharath Balasubramanian, F. Kinose, Haoyu Zeng, 2013, Assay and drug development technologies.

Pharmacology of Azimilide Dihydrochloride (NE-10064), A Class III Antiarrhythmic Agent

R. Brooks, J. Salata, 1997 .

Effects of Sympathetic Tone on Vagally Induced Phasic Changes in Heart Rate and Atrioventricular Node Conduction in the Anesthetized Dog

R. Gilmour, D. Zipes, J. Salata, 1986, Circulation research.

Positive Inotropic and Hemodynamic Properties of Flosequinan, a New Vasodilator, and a Sulfone Metabolite

R. Falotico, A. Tobia, J. Salata, 1989, Journal of cardiovascular pharmacology.

Basis for tetrodotoxin and lidocaine effects on action potentials in dog ventricular myocytes.

J. Salata, J. Wasserstrom, 1988, The American journal of physiology.

Inhibition of prostaglandin synthetase by tolmetin (Tolectin, McN-2559), a new non-steroidal anti-inflammatory agent.

J. Salata, R. Taylor, 1976, Biochemical pharmacology.

Assessing use-dependent inhibition of the cardiac Na(+/-) current (I(Na)) in the PatchXpress automated patch clamp.

J. Imredy, J. Salata, Jacob R. Penniman, 2010, Journal of pharmacological and toxicological methods.

Dantrolene sodium: effects on isolated cardiac tissues.

J. Jalife, J. Salata, J. Wasserstrom, 1983, Journal of molecular and cellular cardiology.

Class III antiarrhythmic activity in vivo by selective blockade of the slowly activating cardiac delayed rectifier potassium current IKs by (R)-2-(2,4-trifluoromethyl)-N-[2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)- 2, 3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]acetamide.

J J Baldwin, M. Sanguinetti, R. Freidinger, 1997, Journal of medicinal chemistry.

Mechanism of action potential prolongation by RP 58866 and its active enantiomer, terikalant. Block of the rapidly activating delayed rectifier K+ current, IKr.

B. Fermini, M. Sanguinetti, M C Sanguinetti, 1996, Circulation.

Comparison of binding to rapidly activating delayed rectifier K+ channel, IKr, and effects on myocardial refractoriness for class III antiarrhythmic agents.

J. Lynch, E. Baskin, J. Salata, 1995, Journal of cardiovascular pharmacology.

Novel, Potent inhibitors of human Kv1.5 K channels and IKur

B. Fermini, J. Salata, A. Lagrutta, 2006 .

Modification of cardiac Na(+) current by RWJ 24517 and its enantiomers in guinea pig ventricular myocytes.

J. Kelly, J. Salata, R. Tsushima, 1999, The Journal of pharmacology and experimental therapeutics.

Pharmacology of RWJ 29009, a new potassium channel activator

R. Falotico, A. Gill, B. Damiano, 1994 .

Effects of 4-aminopyridine on rate-related depression of cardiac action potentials.

R. Gilmour, J. Salata, J. Davis, 1986, The American journal of physiology.

Effects of Quinidine on Action Potentials and Ionic Currents in Isolated Canine Ventricular Myocytes

J. Salata, J. Wasserstrom, 1988, Circulation research.

Modeling Of The Adrenergic Response Of The Human IKs Current (hKCNQ1/hKCNE1) Stably Expressed In HEK-293 Cells

Spencer J. Dech, J. Imredy, J. Salata, 2009 .

Modeling of the adrenergic response of the human IKs current (hKCNQ1/hKCNE1) stably expressed in HEK-293 cells.

Spencer J. Dech, J. Imredy, J. Salata, 2008, American journal of physiology. Heart and circulatory physiology.

Scientific review and recommendations on preclinical cardiovascular safety evaluation of biologics.

Liudmila Polonchuk, Jean-Pierre Valentin, Hugo M Vargas, 2008, Journal of pharmacological and toxicological methods.

A novel benzodiazepine that activates cardiac slow delayed rectifier K+ currents.

M. Sanguinetti, J. Salata, N. Jurkiewicz, 1998, Molecular pharmacology.

Antiarrhythmic efficacy of combined I(Ks) and beta-adrenergic receptor blockade.

N. Liverton, H. Selnick, J. Lynch, 2002, The Journal of pharmacology and experimental therapeutics.

Dynamic Vagal Control of Pacemaker Activity in the Mammalian Sinoatrial Node

J Jalife, D C Michaels, J. Jalife, 1983, Circulation research.

Safety Pharmacology and Regulatory Issues in the Development of Antiarrhythmic Medications

J. Salata, A. Lagrutta, 2009 .

Modulation of Cardiac Arrhythmias by the Autonomic Nervous System

R. Gilmour, D. Zipes, J. Salata, 1989 .

Cardiac electrophysiological actions of the histamine H1-receptor antagonists astemizole and terfenadine compared with chlorpheniramine and pyrilamine.

J. Lynch, J. Salata, N. Jurkiewicz, 1995, Circulation research.

Effects of dantrolene sodium on the electrophysiological properties of canine cardiac Purkinje fibers.

J. Jalife, J. Salata, 1982, The Journal of pharmacology and experimental therapeutics.

muscle Amantadine-induced diastolic depolarization and automaticity in ventricular

J. Jalife, J. Salata, G. Alperovich, 2011 .

Optimization of Ca(v)1.2 screening with an automated planar patch clamp platform.

Bharath Balasubramanian, J. Imredy, J. Salata, 2009, Journal of pharmacological and toxicological methods.

Vagal Control of Pacemaker Periodicity and Intranodal Conduction in the Rabbit Sinoatrial Node

J. Jalife, J. Salata, Victor AJ. Slenter, 1984, Circulation research.

Discovery of triarylethanolamine inhibitors of the Kv1.5 potassium channel.

N. Liverton, C. Claiborne, R. Spencer, 2010, Bioorganic & medicinal chemistry letters.

Novel, Potent Inhibitors of Human Kv1.5 K+ Channels and Ultrarapidly Activating Delayed Rectifier Potassium Current

B. Fermini, J. Salata, A. Lagrutta, 2006, Journal of Pharmacology and Experimental Therapeutics.

Flunarizine is a Highly Potent Inhibitor of Cardiac hERG Potassium Current

Spencer J. Dech, J. Salata, E. Trepakova, 2006, Journal of cardiovascular pharmacology.

IK of rabbit ventricle is composed of two currents: evidence for IKs.

B. Fermini, R. Swanson, K. Folander, 1996, The American journal of physiology.

Synthesis and SAR of 6-substituted purine derivatives as novel selective positive inotropes.

R. Falotico, R. Kanojia, J. Salata, 1992, Journal of medicinal chemistry.

Blockade of HERG channels by the class III antiarrhythmic azimilide: mode of action

F. Lang, A. Busch, A E Busch, 1998, British journal of pharmacology.

Spectrophotometric examination of the optical effects of monolithic multilayered zirconia with different substrates

J. Borbély, P. Hermann, J. Salata, 2020, Advances in Applied Ceramics.

Use‐Dependent Effects of the Class III Antiarrhythmic Agent NE‐10064 (Azimilide) on Cardiac Repolarization: Block of Delayed Rectifier Potassium and L‐Type Calcium Currents

B. Fermini, J. Lynch, E. Baskin, 1995, Journal of cardiovascular pharmacology.

The distribution of acetylcholine and choline in guinea pig heart.

J J Salata, J. Salata, O. M. Brown, 1985, Life sciences.

Left Ventricular Hypertrophy Decreases Slowly but Not Rapidly Activating Delayed Rectifier Potassium Currents of Epicardial and Endocardial Myocytes in Rabbits

P. Kowey, Xiaoping Xu, Ying Wu, 2001, Circulation.

(Fade) of Hyperpolarizing Responses to Vagal Stimulation at the Sinoatrial and Atrioventricular Nodes of the Rabbit Heart

J. Jalife, J. Salata, Joseph J. Salata, 1985, Circulation research.

In Vivo Canine Cardiac Electrophysiologic Profile of 1,4‐Benzodiazepine Iks Blockers

A. Tebben, H. Selnick, J. Lynch, 2003, Journal of cardiovascular pharmacology.

Novel 5-cyclopropyl-1,4-benzodiazepin-2-ones as potent and selective I(Ks)-blocking class III antiarrhythmic agents.

R. Freidinger, N. Liverton, C. Dieckhaus, 2003, Bioorganic & medicinal chemistry letters.

The anesthetized guinea pig: an effective early cardiovascular derisking and lead optimization model.

M. Nishida, K. Hoagland, J. Imredy, 2013, Journal of pharmacological and toxicological methods.

Time course of AV nodal conduction responses to brief repetitive vagal stimuli is phase-dependent

R. Gilmour, D. Zipes, J. Salata, 1985 .

R. Gilmour, D. Zipes, J. Salata, 1985, Circulation research.

Thiophene systems. 14. Synthesis and antihypertensive activity of novel 7-(cyclic amido)-6-hydroxythieno[3,2-b]pyrans and related compounds as new potassium channel activators.

R. Falotico, J. Salata, J. Press, 1992, Journal of medicinal chemistry.

MK-0448, a Specific Kv1.5 Inhibitor: Safety, Pharmacokinetics, and Pharmacodynamic Electrophysiology in Experimental Animal Models and Humans

W. Kraft, H. Greenberg, C. Regan, 2012, Circulation. Arrhythmia and electrophysiology.

Amantadine‐Induced Diastolic Depolarization and Automaticity in Ventricular Muscle

J. Jalife, J. Salata, J. Megna, 1982, Circulation research.

K+ currents expressed from the guinea pig cardiac IsK protein are enhanced by activators of protein kinase C.

E. Lazarides, R. Swanson, K. Folander, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Application of PatchXpress planar patch clamp technology to the screening of new drug candidates for cardiac KCNQ1/KCNE1 (I Ks) activity.

Spencer J. Dech, J. Imredy, J. Salata, 2007, Assay and drug development technologies.