D. D’Argenio

发表

The Efficiency, Efficacy, and Retention of Task Practice in Chronic Stroke

N. Schweighofer, C. Winstein, Chunji Wang, 2020, Neurorehabilitation and neural repair.

Predicting monoclonal antibody pharmacokinetics following subcutaneous administration via whole-body physiologically-based modeling

D. D’Argenio, Shihao Hu, 2020, Journal of Pharmacokinetics and Pharmacodynamics.

FLT3 and CDK4/6 inhibitors: Signaling mechanisms and tumor burden in subcutaneous and orthotopic mouse models of acute myeloid leukemia

Yu-Nien Sun, Cheng-Pang Hsu, Yaping Zhang, 2014, Journal of Pharmacokinetics and Pharmacodynamics.

Regenerative Markov Chain Monte Carlo Methods for Pharmacokinetic/Pharmacodynamic Estimation

A. Schumitzky, D. D’Argenio, D. Kang, 2004 .

Targeting the systemic exposure of teniposide in the population and the individual using a stochastic therapeutic objective

J. Rodman, D. D’Argenio, 1993, Journal of Pharmacokinetics and Biopharmaceutics.

Population-Based Efficacy Modeling of Omalizumab in Patients with Severe Allergic Asthma Inadequately Controlled with Standard Therapy

M. Eisner, J. Matthews, R. Zhu, 2013, The AAPS Journal.

Bayesian Inference in Physiologically-based Pharmacokinetic Modeling: Application to Aniticancer Drug Development

M. Egorin, D. D’Argenio, J. Eiseman, 2004 .

Predicting Chemotherapy-Induced Neutropenia and Granulocyte Colony–Stimulating Factor Response Using Model-Based In Vitro to Clinical Translation

M. Spilker, T. Sung, Wenyue Hu, 2020, The AAPS Journal.

Experimental design for estimating integrals by numerical quadrature, with applications to pharmacokinetic studies.

D. Katz, D Z D'Argenio, D. D’Argenio, 1983, Biometrics.

A kinetic model for99mTc-DMSA in the rat

W. Wolf, D. Maneval, D. D’Argenio, 2005, European Journal of Nuclear Medicine.

Adaptive control of theophylline therapy: Importance of blood sampling times

D. D’Argenio, K. Khakmahd, 1983, Journal of Pharmacokinetics and Biopharmaceutics.

Characteristics of Passive Solute Transport across Primary Rat Alveolar Epithelial Cell Monolayers

E. Crandall, Kwang-Jin Kim, D. D’Argenio, 2021, Membranes.

Isoniazid Pharmacokinetics, Pharmacodynamics, and Dosing in South African Infants

S. Madhi, C. Fletcher, V. Carey, 2012, Therapeutic drug monitoring.

Analysis of Intravenous Glucose Tolerance Test Data Using Parametric and Nonparametric Modeling: Application to a Population at Risk for Diabetes

Dae C. Shin, G. Pacini, V. Marmarelis, 2013, Journal of diabetes science and technology.

Human insulin dynamics in women: a physiologically based model.

A. Tura, G. Pacini, M. Weiss, 2016, American journal of physiology. Regulatory, integrative and comparative physiology.

In vitro study on the pressure drop-flow relationship of a compliant coronary stenosis

M. Siebes, D. D’Argenio, 1989, Images of the Twenty-First Century. Proceedings of the Annual International Engineering in Medicine and Biology Society,.

Glucagon increases insulin levels by stimulating insulin secretion without effect on insulin clearance in mice

G. Pacini, B. Ahrén, D. D’Argenio, 2017, Peptides.

Prediction of human functional genetic networks from heterogeneous data using RVM-based ensemble learning

S. Asgharzadeh, T. Triche, D. D’Argenio, 2010, Bioinform..

A physiological model of granulopoiesis to predict clinical drug induced neutropenia from in vitro bone marrow studies: with application to a cell cycle inhibitor

M. Spilker, Diane D. Wang, Yanke Yu, 2020, Journal of Pharmacokinetics and Pharmacodynamics.

Glucagon clearance is regulated by nutritional state: evidence from experimental studies in mice

G. Pacini, B. Ahrén, D. D’Argenio, 2014, Diabetologia.

Stochastic Control of Pharmaco-Kinetic Systems: Open-Loop Feedback Strategies

D. Katz, D. D’Argenio, 1988 .

Population Pharmacokinetic Modeling of Plasma and Intracellular Ribavirin Concentrations in Patients with Chronic Hepatitis C Virus Infection

G. Everson, T. Urban, P. Anderson, 2015, Antimicrobial Agents and Chemotherapy.

The Efficiency, Efficacy, and Retention of Motor Training in Chronic Stroke

N. Schweighofer, C. Winstein, Chunji Wang, 2020, bioRxiv.

Effects of increasing doses of glucagon-like peptide-1 on insulin-releasing phases during intravenous glucose administration in mice.

G. Pacini, B. Ahrén, D. D’Argenio, 2011, American journal of physiology. Regulatory, integrative and comparative physiology.

Physiologically Based Modeling to Predict Monoclonal Antibody Pharmacokinetics in Humans from in vitro Physiochemical Properties

A. Datta-Mannan, D. D’Argenio, Shihao Hu, 2022, mAbs.

Vitreous VEGF clearance is increased after vitrectomy.

K. Csaky, B. Kuppermann, Zhiling Yu, 2010, Investigative ophthalmology & visual science.

A whole‐body circulatory neutrophil model with application to predicting clinical neutropenia from in vitro studies

M. Spilker, Wenyue Hu, D. D’Argenio, 2021, CPT: pharmacometrics & systems pharmacology.

Intracellular Metabolism of Lamivudine

J. Rodman, D. D’Argenio, B. Robbins, 2004 .

Isoniazid The Pharmacogenetics of NAT 2 Enzyme Maturation in Perinatally HIV Exposed Infants Receiving

C. Werely, D. D’Argenio, J. Kiser, 2011 .

Pharmacokinetics of Doxycycline in Adults with Cystic Fibrosis

D. D’Argenio, P. Beringer, A. Rao, 2011, Antimicrobial Agents and Chemotherapy.

Analysis of segmental phosphate absorption in intact rats. A compartmental analysis approach.

J. Meyer, D. D’Argenio, D. B. Lee, 1993, The Journal of clinical investigation.

Feedback control indirect response models

D. D’Argenio, Yaping Zhang, 2016, Journal of Pharmacokinetics and Pharmacodynamics.

Evaluation of variance approximation techniques for non-linear photosynthesis—irradiance models

J. Kremer, R. Zimmerman, J. Soohoo, 1987 .

Population pharmacokinetic/pharmacodynamic mixture models via maximum a posteriori estimation

Xiaoning Wang, David Z. D'Argenio, Alan Schumitzky, 2009, Comput. Stat. Data Anal..

Nonlinear random effects mixture models: Maximum likelihood estimation via the EM algorithm

Xiaoning Wang, David Z. D'Argenio, Alan Schumitzky, 2007, Comput. Stat. Data Anal..

A program package for simulation and parameter estimation in pharmacokinetic systems.

A Schumitzky, D Z D'Argenio, A. Schumitzky, 1979, Computer programs in biomedicine.

Monoclonal Antibody Pharmacokinetics in Cynomolgus Monkeys Following Subcutaneous Administration: Physiologically Based Model Predictions from Physiochemical Properties

A. Datta-Mannan, D. D’Argenio, Shihao Hu, 2022, The AAPS Journal.

Predicting monoclonal antibody pharmacokinetics following subcutaneous administration via whole-body physiologically-based modeling

D. D’Argenio, Shihao Hu, 2020, Journal of Pharmacokinetics and Pharmacodynamics.

Model for Intracellular Lamivudine Metabolism in Peripheral Blood Mononuclear Cells Ex Vivo and in Human Immunodeficiency Virus Type 1-Infected Adolescents

David Z. D'Argenio, Patricia M. Flynn, John H. Rodman, 2006, Antimicrobial Agents and Chemotherapy.

Simulation of linear compartment models with application to nuclear medicine kinetic modeling.

A Schumitzky, A. Schumitzky, D Z D'Argenio, 1988, Computer methods and programs in biomedicine.

A Mass Balance and Disposition Study of the DNA Methyltransferase Inhibitor Zebularine (NSC 309132) and Three of Its Metabolites in Mice

R. Parker, M. Egorin, J. Beumer, 2006, Clinical Cancer Research.

Plasma pharmacokinetics and oral bioavailability of 3,4,5,6-tetrahydrouridine, a cytidine deaminase inhibitor, in mice

R. Parker, M. Egorin, J. Beumer, 2007, Cancer Chemotherapy and Pharmacology.

Plasma pharmacokinetics and oral bioavailability of the 3,4,5,6-tetrahydrouridine (THU) prodrug, triacetyl-THU (taTHU), in mice

P. Hershberger, M. Egorin, M. Ames, 2011, Cancer Chemotherapy and Pharmacology.

The Triple Combination Indinavir-Zidovudine-Lamivudine Is Highly Synergistic

J. Bilello, O. Weislow, G. Drusano, 2000, Antimicrobial Agents and Chemotherapy.

Kinetic modeling of 5-fluorouracil anabolism in colorectal adenocarcinoma: a positron emission tomography study in rats.

J. Bading, P. Conti, M. Alauddin, 2003, Cancer research.

Plasma Pharmacokinetics, Oral Bioavailability, and Interspecies Scaling of the DNA Methyltransferase Inhibitor, Zebularine

Alexander V. Lyubimov, David Z. D'Argenio, Julie L. Eiseman, 2005, Clinical Cancer Research.

Optimal sampling times for pharmacokinetic experiments

David Z. D'Argenio, D. D’Argenio, 1981, Journal of Pharmacokinetics and Biopharmaceutics.

Pharmacodynamic model of topotecan-induced time course of neutropenia.

M. Egorin, A. Farese, T. MacVittie, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Intracellular-signaling tumor-regression modeling of the pro-apoptotic receptor agonists dulanermin and conatumumab

Yu-Nien Sun, Cheng-Pang Hsu, Yan Xin, 2012, Journal of Pharmacokinetics and Pharmacodynamics.

Use of Drug Effect Interaction Modeling with Monte Carlo Simulation To Examine the Impact of Dosing Interval on the Projected Antiviral Activity of the Combination of Abacavir and Amprenavir

J. Bilello, G. Drusano, M. Rogers, 2000, Antimicrobial Agents and Chemotherapy.

Integrated Population Pharmacokinetic/Viral Dynamic Modelling of Lopinavir/Ritonavir in HIV-1 Treatment-Naïve Patients

E. Acosta, Kun Wang, I. Ofotokun, 2014, Clinical Pharmacokinetics.

A Note on Population Analysis of Dissolution‐Absorption Models Using the Inverse Gaussian Function

M. Weiss, D. D’Argenio, Jian Wang, 2008, Journal of clinical pharmacology.

FLT3 and CDK4/6 inhibitors: Signaling mechanisms and tumor burden in subcutaneous and orthotopic mouse models of acute myeloid leukemia

Yu‐Nien Sun, Cheng-Pang Hsu, Yilong Zhang, 2014, Journal of Pharmacokinetics and Pharmacodynamics.

TARGETgene: A Tool for Identification of Potential Therapeutic Targets in Cancer

Shahab Asgharzadeh, Timothy Triche, T. Triche, 2012, PloS one.

Optimal inputs for parameter determination of inert gas washout from the lung.

S M Lewis, G A Bekey, G. Bekey, 1982, Respiration physiology.

A local effect of CYP24 inhibition on lung tumor xenograft exposure to 1,25-dihydroxyvitamin D3 is revealed using a novel LC–MS/MS assay

P. Hershberger, M. Petkovich, J. Beumer, 2012, Steroids.

A minimal model of liver glycogen metabolism; feasibility for predicting flux rates.

I. Kurland, D. D’Argenio, 1988, Journal of theoretical biology.

Noninvasive estimation of bound and mobile platinum compounds in the kidney using a radiopharmacokinetic model.

W Wolf, R. Brechner, W. Wolf, 1986, Journal of pharmaceutical sciences.

The Emerging Scientific Discipline of Pharmacometrics

M. Pfister, D. D’Argenio, 2010, Journal of clinical pharmacology.

Analysis of Complex Absorption After Multiple Dosing: Application to the Interaction Between the P-glycoprotein Substrate Talinolol and Rifampicin

M. Weiss, W. Siegmund, D. D’Argenio, 2022, Pharmaceutical research.

RAD-ADAPT: Software for modelling clonogenic assay data in radiation biology.

C. Bakkenist, J. Beumer, D. D’Argenio, 2017, DNA repair.

Pharmacokinetics of Tedizolid in Plasma and Sputum of Adults with Cystic Fibrosis

D. D’Argenio, P. Beringer, Jordanna G Jayne, 2018, Antimicrobial Agents and Chemotherapy.

Population-based meta-analysis of roxithromycin pharmacokinetics: dosing implications of saturable absorption and protein binding

D. D’Argenio, M. Dolton, 2016, The Journal of antimicrobial chemotherapy.

Control of Uncertain Pharmacodynamic Systems

David Z. D'Argenio, Kyungsoo Park, Kyungsoo Park, 2004 .

Uncertain pharmacokinetic/pharmacodynamic systems: Design, estimation and control

David Z. D'Argenio, D. D’Argenio, Kyungsoo Park, 1997 .

Incorporating prior parameter uncertainty in the design of sampling schedules for pharmacokinetic parameter estimation experiments.

D Z D'Argenio, D. D’Argenio, 1990, Mathematical biosciences.

Fluid dynamics of a partially collapsible stenosis in a flow model of the coronary circulation.

M. Siebes, D. D’Argenio, C. Campbell, 1996, Journal of biomechanical engineering.

Computer assessment of hemodynamic severity of coronary artery stenosis from angiograms.

R H Selzer, M Siebes, M. Siebes, 1985, Computer methods and programs in biomedicine.

The Pharmacogenetics of NAT2 Enzyme Maturation in Perinatally HIV Exposed Infants Receiving Isoniazid

C. Fletcher, C. Werely, D. D’Argenio, 2012, Journal of clinical pharmacology.

Bayesian Analysis of Pharmacokinetic Models with Applications to Dosing Regimen Determination.

David Z. D'Argenio, Alan Schumitzky, D. Katz, 1980 .

Stochastic control of pharmacokinetic systems

Roger W. Jelliffe, Mark H. Milman, David Z. D'Argenio, 1983 .

Monoclonal Antibody Pharmacokinetics in Cynomolgus Monkeys Following Subcutaneous Administration: Physiologically Based Model Predictions from Physiochemical Properties

A. Datta-Mannan, D. D’Argenio, Shihao Hu, 2022, The AAPS Journal.

Feedback control indirect response models

Yaping Zhang, David Z. D’Argenio, D. D’Argenio, 2016, Journal of Pharmacokinetics and Pharmacodynamics.

Pharmacokinetic-Pharmacodynamic Target Attainment Analyses To Determine Optimal Dosing of Ceftazidime-Avibactam for the Treatment of Acute Pulmonary Exacerbations in Patients with Cystic Fibrosis

D. D’Argenio, P. Beringer, Timothy J. Bensman, 2017, Antimicrobial Agents and Chemotherapy.

Pharmacokinetic Modeling to Improve the Design of Intravitreal Corticosteroid Implants for Treating Macular Edema

R. Moats, S. Whitcup, M. Robinson, 2007 .

Population-Based Efficacy Modeling of Omalizumab in Patients with Severe Allergic Asthma Inadequately Controlled with Standard Therapy

M. Eisner, J. Matthews, D. D’Argenio, 2013, The AAPS Journal.

Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis

David Z. D'Argenio, D. D’Argenio, 2004, Springer US.

Intracellular-signaling tumor-regression modeling of the pro-apoptotic receptor agonists dulanermin and conatumumab

Yu‐Nien Sun, Cheng-Pang Hsu, Y. Xin, 2012, Journal of Pharmacokinetics and Pharmacodynamics.

An Analysis of Glucose Effectiveness in Subjects With or Without Type 2 Diabetes via Hierarchical Modeling

A. Tura, G. Pacini, D. D’Argenio, 2021, Frontiers in Endocrinology.

Bortezomib interactions with chemotherapy agents in acute leukemia in vitro

S. Plon, T. Horton, S. Berg, 2006, Cancer Chemotherapy and Pharmacology.

On the correction for radioactive decay in pharmacokinetic modeling.

J. Wong, T. Odom-Maryon, L. Williams, 1995, Medical physics.

Nucleoside Analog 1592U89 and Human Immunodeficiency Virus Protease Inhibitor 141W94 Are Synergistic In Vitro

J. Bilello, G. Drusano, B. Sadler, 1998, Antimicrobial Agents and Chemotherapy.

Population Pharmacokinetic Modeling of Vancomycin in Thai Patients with Heterogeneous and Unstable Renal Function.

P. Sermsappasuk, D. D’Argenio, S. Jaisue, 2020, Therapeutic drug monitoring.

Prediction of human functional genetic networks from heterogeneous data using RVM-based ensemble learning

David Z. D'Argenio, Chia-Chin Wu, Shahab Asgharzadeh, 2010, Bioinform..

Synergy of karenitecin and mafosfamide in pediatric leukemia, medulloblastoma, and neuroblastoma cell lines

S. Berg, D. D’Argenio, S. Blaney, 2008, Pediatric blood & cancer.

The Funnel: a Screening Technique for Identifying Optimal Two-Drug Combination Chemotherapy Regimens

W. Yamada, M. Neely, G. Drusano, 2020, Antimicrobial Agents and Chemotherapy.

Physiologically-Based Pharmacokinetics and Molecular Pharmacodynamics of 17-(allylamino)-17-demethoxygeldanamycin and Its Active Metabolite in Tumor-Bearing Mice

David Z. D'Argenio, Julie L. Eiseman, Merrill J. Egorin, 2003, Journal of Pharmacokinetics and Pharmacodynamics.

Editorial: Special Issue on Multiscale Modeling and Analysis in Computational Biology and Medicine—Part-1

Alejandro F. Frangi, Jean-Louis Coatrieux, Anushka Michailova, 2011, IEEE Transactions on Biomedical Engineering.

Biokinetic Modeling of Nanoparticle Interactions with Lung Alveolar Epithelial Cells: Uptake, Intracellular Processing and Egress.

E. Crandall, A. Sipos, Kwang-Jin Kim, 2020, American journal of physiology. Regulatory, integrative and comparative physiology.

Long-term forecasting of a motor outcome following rehabilitation in chronic stroke via a hierarchical bayesian dynamic model

Haipeng Luo, N. Schweighofer, C. Winstein, 2023, Journal of NeuroEngineering and Rehabilitation.

Physiological Modeling of the Small Intestine in Drug Absorption

A. Schumitzky, D. DuBois, R. Almon, 2004 .

Implementation and evaluation of control strategies for individualizing dosage regimens, with application to the aminoglycoside antibiotics

D. Katz, D. D’Argenio, 1986, Journal of Pharmacokinetics and Biopharmaceutics.

Sampling strategies for noncompartmental estimation of mean residence time

D. Katz, D. D’Argenio, 1983, Journal of Pharmacokinetics and Biopharmaceutics.

Non-linear IV pharmacokinetics of the ATR inhibitor berzosertib (M6620) in mice.

C. Bakkenist, D. D’Argenio, R. Parise, 2024, Cancer chemotherapy and pharmacology.

ACoP: The Tools, Carpenters, and Architects Building the Discipline of Pharmacometrics

Raymond Miller, Richard C Brundage, Marc Pfister, 2010, Journal of clinical pharmacology.