M. Vizuete

发表

Early neuronal loss and axonal/presynaptic damage is associated with accelerated amyloid-β accumulation in AβPP/PS1 Alzheimer's disease mice subiculum.

A. Gutiérrez, J. Vitorica, Javier Vitorica, 2014, Journal of Alzheimer's disease : JAD.

Transgenic Mouse Models of Alzheimer’s Disease: An Integrative Analysis

A. Gutiérrez, J. Vitorica, Elisabeth Sánchez-Mejías, 2022, International journal of molecular sciences.

Age-dependent Accumulation of Soluble Amyloid β (Aβ) Oligomers Reverses the Neuroprotective Effect of Soluble Amyloid Precursor Protein-α (sAPPα) by Modulating Phosphatidylinositol 3-Kinase (PI3K)/Akt-GSK-3β Pathway in Alzheimer Mouse Model*

D. Ruano, A. Gutiérrez, J. Vitorica, 2011, The Journal of Biological Chemistry.

Phagocytic clearance of presynaptic dystrophies by reactive astrocytes in Alzheimer's disease

E. Galea, J. Comella, A. Gutiérrez, 2017, Glia.

Should We Open Fire on Microglia? Depletion Models as Tools to Elucidate Microglial Role in Health and Alzheimer’s Disease

A. Gutiérrez, J. Vitorica, M. Vizuete, 2021, International journal of molecular sciences.

Amyloid‐β impairs the phagocytosis of dystrophic synapses by astrocytes in Alzheimer's disease

E. Galea, A. Gutiérrez, J. Vitorica, 2020, Glia.

Hypoxia compromises the mitochondrial metabolism of Alzheimer’s disease microglia via HIF1

J. López-Barneo, Antonio Heras-Garvin, A. Serrano‐Pozo, 2021, Nature Aging.

Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer’s mice hippocampus

Antonia Gutierrez, Raquel Sanchez-Varo, J. García-Verdugo, 2011, Acta Neuropathologica.

Disruption of Amyloid Plaques Integrity Affects the Soluble Oligomers Content from Alzheimer Disease Brains

J. Moyano, A. Gutiérrez, J. Vitorica, 2014, PloS one.

Microglia in Alzheimer’s Disease: Activated, Dysfunctional or Degenerative

A. Gutiérrez, J. Vitorica, J. Davila, 2018, Front. Aging Neurosci..

Soluble phospho-tau from Alzheimer’s disease hippocampus drives microglial degeneration

A. Gutiérrez, J. Vitorica, J. Davila, 2016, Acta Neuropathologica.

Distinct Microglial Responses in Two Transgenic Murine Models of TAU Pathology

A. Gutiérrez, J. Vitorica, Raquel Sánchez‐Varo, 2018, Front. Cell. Neurosci..

In vivo modification of Abeta plaque toxicity as a novel neuroprotective lithium-mediated therapy for Alzheimer’s disease pathology

A. Gutiérrez, J. Vitorica, J. Davila, 2013, Acta neuropathologica communications.

Inflammatory Response in the Hippocampus of PS1M146L/APP751SL Mouse Model of Alzheimer's Disease: Age-Dependent Switch in the Microglial Phenotype from Alternative to Classic

D. Ruano, A. Gutiérrez, J. Vitorica, 2008, The Journal of Neuroscience.

Plaque-Associated Oligomeric Amyloid-Beta Drives Early Synaptotoxicity in APP/PS1 Mice Hippocampus: Ultrastructural Pathology Analysis

A. Gutiérrez, J. Vitorica, J. Davila, 2021, Frontiers in Neuroscience.

Extracellular amyloid-beta and cytotoxic glial activation induce significant entorhinal neuron loss in young PS1(M146L)/APP(751SL) mice.

M. Romero-Acebal, D. Ruano, A. Gutiérrez, 2009, Journal of Alzheimer's disease : JAD.

Defective lysosomal proteolysis and axonal transport are early pathogenic events that worsen with age leading to increased APP metabolism and synaptic Abeta in transgenic APP/PS1 hippocampus

Antonia Gutierrez, Raquel Sanchez-Varo, A. Gutiérrez, 2012, Molecular Neurodegeneration.

Enhancing microtubule stabilization rescues cognitive deficits and ameliorates pathological phenotype in an amyloidogenic Alzheimer’s disease model

A. Gutiérrez, J. Vitorica, J. Davila, 2020, Scientific Reports.

Heterogeneity in the Allosteric Interaction Between the γ‐Aminobutyric Acid (GABA) Binding Site and Three Different Benzodiazepine Binding Sites of the GABAA/Benzodiazepine Receptor Complex in the Rat Nervous System

J. Cano, D. Ruano, J. Vitorica, 1992, Journal of neurochemistry.

Differential Upregulation of Aquaporin-4 mRNA Expression in Reactive Astrocytes after Brain Injury: Potential Role in Brain Edema

C. Vargas, J. Cano, J. L. Venero, 1999, Neurobiology of Disease.

Defective lysosomal proteolysis and axonal transport are early pathogenic events that worsen with age leading to increased APP metabolism and synaptic Abeta in transgenic APP/PS1 hippocampus

A. Gutiérrez, J. Vitorica, J. Davila, 2012, Molecular Neurodegeneration.

Calretinin interneurons are early targets of extracellular amyloid-beta pathology in PS1/AbetaPP Alzheimer mice hippocampus.

M. Romero-Acebal, D. Ruano, A. Gutiérrez, 2010, Journal of Alzheimer's disease : JAD.

Dual roles of Aβ in proliferative processes in an amyloidogenic model of Alzheimer’s disease

J. García-Verdugo, A. Gutiérrez, J. Vitorica, 2017, Scientific Reports.

Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-β Peptide Generation In Vivo

J. López-Barneo, Antonio Heras-Garvin, A. Serrano‐Pozo, 2017, PloS one.

Upregulation of BDNF mRNA and trkB mRNA in the Nigrostriatal System and in the Lesion Site Following Unilateral Transection of the Medial Forebrain Bundle

C. Vargas, J. Cano, J. L. Venero, 2000, Experimental Neurology.

Detailed localization of aquaporin-4 messenger RNA in the CNS: preferential expression in periventricular organs

J. Cano, J. L. Venero, A. Machado, 1999, Neuroscience.

Monocyte-derived cells invade brain parenchyma and amyloid plaques in human Alzheimer’s disease hippocampus

A. Gutiérrez, J. Vitorica, M. Vizuete, 2023, Acta Neuropathologica Communications.

Inter‐individual variability in the expression of the mutated form of hPS1M146L determined the production of Aβ peptides in the PS1xAPP transgenic mice

D. Ruano, A. Gutiérrez, J. Vitorica, 2007, Journal of neuroscience research.