M. Robinson

发表

J. Dalton, J. McKerrow, P. Brindley, 2013 .

The phylogeny, structure and function of trematode cysteine proteases, with particular emphasis on the Fasciola hepatica cathepsin L family.

J. Dalton, M. Robinson, C. Stack, 2011, Advances in experimental medicine and biology.

Collagenolytic Activities of the Major Secreted Cathepsin L Peptidases Involved in the Virulence of the Helminth Pathogen, Fasciola hepatica

Joyce To, Gabriel Rinaldi, J. Dalton, 2011, PLoS neglected tropical diseases.

An Integrated Transcriptomics and Proteomics Analysis of the Secretome of the Helminth Pathogen Fasciola hepatica

Shoba Ranganathan, Ranjeeta Menon, S. Ranganathan, 2009, Molecular & Cellular Proteomics.

Proteomics and Phylogenetic Analysis of the Cathepsin L Protease Family of the Helminth Pathogen Fasciola hepatica

Ben Herbert, J. Dalton, B. Herbert, 2008, Molecular & Cellular Proteomics.

Cathelicidin-like Helminth Defence Molecules (HDMs): Absence of Cytotoxic, Anti-microbial and Anti-protozoan Activities Imply a Specific Adaptation to Immune Modulation

J. Dalton, Sophie Cotton, K. Thivierge, 2013, PLoS neglected tropical diseases.

Extracellular Vesicle Biogenesis in Helminths: More than One Route to the Surface?

G. Brennan, M. Robinson, Eduardo de la Torre-Escudero, 2016, Trends in parasitology.

Helminth genome analysis reveals conservation of extracellular vesicle biogenesis pathways but divergence of RNA loading machinery between phyla.

M. Robinson, Eduardo de la Torre-Escudero, Adam P S Bennett, 2020, International journal for parasitology.

Immunomodulatory molecules of Fasciola hepatica: candidates for both vaccine and immunotherapeutic development.

J. Dalton, S. O'Neill, G. Mulcahy, 2013, Veterinary parasitology.

MHJ_0125 is an M42 glutamyl aminopeptidase that moonlights as a multifunctional adhesin on the surface of Mycoplasma hyopneumoniae

C. Whitchurch, L. Turnbull, M. Labbate, 2013, Open Biology.

How Pathogen-Derived Cysteine Proteases Modulate Host Immune Responses

J. Dalton, M. Robinson, S. Donnelly, 2011, Advances in experimental medicine and biology.

A possible model of benzimidazole binding to beta-tubulin disclosed by invoking an inter-domain movement.

I. Fairweather, N. Mcferran, M. Robinson, 2004, Journal of molecular graphics & modelling.

Immune Cell Profiling of IFN-λ Response Shows pDCs Express Highest Level of IFN-λR1 and Are Directly Responsive via the JAK-STAT Pathway.

C. Biron, C. O’Farrelly, M. Robinson, 2016, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Elevated interferon-stimulated gene transcription in peripheral blood mononuclear cells occurs in patients infected with genotype 1 but not genotype 3 hepatitis C virus

J. McLauchlan, P. Mills, M. Robinson, 2014, Journal of viral hepatitis.

Secretion and processing of a novel multi-domain cystatin-like protein by intracellular stages of Trichinella spiralis.

M. Robinson, B. Connolly, D. Massie, 2007, Molecular and biochemical parasitology.

A helminth cathelicidin‐like protein suppresses antigen processing and presentation in macrophages via inhibition of lysosomal vATPase

J. Dalton, C. Whitchurch, L. Turnbull, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Profiling excretory/secretory proteins of Trichinella spiralis muscle larvae by two-dimensional gel electrophoresis and mass spectrometry.

M. Robinson, B. Connolly, D. Gare, 2005, Veterinary parasitology.

Extracellular vesicle-mediated communication in host-parasite interactions: insight from Fasciola hepatica.

M. Robinson, Eduardo de la Torre-Escudero, 2017, Annals of translational medicine.

Calicophoron daubneyi—The Path Toward Understanding Its Pathogenicity and Host Interactions

P. Skuce, T. McNeilly, M. Robinson, 2020, Frontiers in Veterinary Science.

Surface molecules of extracellular vesicles secreted by the helminth pathogen Fasciola hepatica direct their internalisation by host cells

J. Dalton, S. O'Neill, L. Joshi, 2019, PLoS neglected tropical diseases.

Fasciola gigantica: Comparison of the tegumental ultrastructure in newly excysted metacercariae and in vitro penetrated juvenile flukes indicates intracellular sources of molecules with vaccinal and immunomodulatory potential.

I. Fairweather, G. Brennan, W. Jura, 2019, Veterinary parasitology.

Defense peptides secreted by helminth pathogens: antimicrobial and/or immunomodulator molecules?

J. Dalton, Sophie Cotton, K. Thivierge, 2012, Front. Immun..

Helminth Cysteine Proteases Inhibit TRIF-dependent Activation of Macrophages via Degradation of TLR3

J. Dalton, C. Whitchurch, L. Turnbull, 2009, The Journal of Biological Chemistry.

Fasciola hepatica: the therapeutic potential of a worm secretome.

J. Dalton, B. O'Brien, M. Robinson, 2013, International journal for parasitology.

Worm secretory molecules are causing alarm.

J. Dalton, M. Robinson, S. Donnelly, 2010, Trends in parasitology.

The effect of the microtubule inhibitor tubulozole-C on the tegument of triclabendazole-susceptible and triclabendazole-resistant Fasciola hepatica

I. Fairweather, E. Hoey, M. Robinson, 2003, Parasitology Research.

RNA interference targeting cathepsin B of the carcinogenic liver fluke, Opisthorchis viverrini.

A. Loukas, N. Young, R. Gasser, 2011, Parasitology international.

Secreted Proteins from the Helminth Fasciola hepatica Inhibit the Initiation of Autoreactive T Cell Responses and Prevent Diabetes in the NOD Mouse

J. Dalton, A. Simpson, B. O'Brien, 2014, PloS one.

The Plasmodium falciparum Malaria M1 Alanyl Aminopeptidase (PfA-M1): Insights of Catalytic Mechanism and Function from MD Simulations

J. Dalton, A. M. George, Peter M. S. Jones, 2011, PloS one.

Liver-Derived TGF-β Maintains the EomeshiTbetlo Phenotype of Liver Resident Natural Killer Cells

J. Geoghegan, D. Houlihan, C. O’Farrelly, 2019, Front. Immunol..

The immune modulatory peptide FhHDM‐1 secreted by the helminth Fasciola hepatica prevents NLRP3 inflammasome activation by inhibiting endolysosomal acidification in macrophages

J. Dalton, A. Mansell, B. O'Brien, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Anti‐envelope antibody responses in individuals at high risk of hepatitis C virus who resist infection

J. McLauchlan, S. Foung, M. Robinson, 2016, Journal of viral hepatitis.

Foodborne trematodes: old foes, new kids on the block and research perspectives for control and understanding host–parasite interactions

J. Sotillo, M. Robinson, 2022, Parasitology.

Fasciola hepatica Gastrodermal Cells Selectively Release Extracellular Vesicles via a Novel Atypical Secretory Mechanism

M. Robinson, R. Hanna, Eduardo de la Torre-Escudero, 2022, International journal of molecular sciences.

The effect of naturally acquired rumen fluke infection on animal health and production in dairy and beef cattle in the UK

Bernard O. Lagan, M. Robinson, A. Aubry, 2022, Frontiers in Veterinary Science.

RNA sequencing of LX-2 cells treated with TGF-β1 identifies genes associated with hepatic stellate cell activation

G. Ramm, M. Robinson, G. Gobert, 2021, Molecular Biology Reports.

RNA Sequencing of LX-2 Cells Treated with TGF-β1 Identi es Genes Associated with Early Hepatic Stellate Cell Activation

M. Robinson, G. Gobert, Jack P. Carson, 2021 .

Mechanisms of immune modulation by Fasciola hepatica: importance for vaccine development and for novel immunotherapeutics

J. Dalton, S. O'Neill, M. Robinson, 2011 .

Understanding triclabendazole resistance.

G. Virkel, C. Lanusse, P. Brophy, 2007, Experimental and molecular pathology.

Triclabendazole-resistant Fasciola hepatica: β-tubulin and response to in vitro treatment with triclabendazole

I. Fairweather, E. Hoey, M. Robinson, 2002, Parasitology.

Non cell autonomous upregulation of CDKN2 transcription linked to progression of chronic hepatitis C disease

Arvind H. Patel, J. McLauchlan, P. Mills, 2013, Aging cell.

Tissue‐resident Eomeshi T‐betlo CD56bright NK cells with reduced proinflammatory potential are enriched in the adult human liver

J. Geoghegan, D. Houlihan, C. O’Farrelly, 2016, European journal of immunology.

A parasite-derived 68-mer peptide ameliorates autoimmune disease in murine models of Type 1 diabetes and multiple sclerosis

J. Dalton, A. Simpson, B. O'Brien, 2016, Scientific Reports.

Enhanced cytokine responsiveness in natural killer cells from a pilot cohort of uninfected seronegative women exposed to hepatitis C virus contaminated anti-D immunoglobulin

D. Houlihan, C. O’Farrelly, L. Fanning, 2019, bioRxiv.

Aminopeptidases of malaria parasites: new targets for chemotherapy.

J. Dalton, K. Trenholme, D. Gardiner, 2010, Infectious disorders drug targets.

Characterisation of a β-tubulin gene from the liver fluke, Fasciola hepatica

J. Dalton, I. Fairweather, E. Hoey, 2001 .

A comparative proteomics analysis of the egg secretions of three major schistosome species.

M. Hsieh, D. McManus, M. Robinson, 2020, Molecular and biochemical parasitology.

Zoonotic helminth infections with particular emphasis on fasciolosis and other trematodiases

J. Dalton, M. Robinson, 2009, Philosophical Transactions of the Royal Society B: Biological Sciences.

Drug resistance in liver flukes

I. Fairweather, P. Skuce, G. Brennan, 2020, International journal for parasitology. Drugs and drug resistance.

Liver immunology and its role in inflammation and homeostasis

C. O’Farrelly, M. Robinson, C. Harmon, 2016, Cellular & Molecular Immunology.

The comparative metabolism of triclabendazole sulphoxide by triclabendazole-susceptible and triclabendazole-resistant Fasciola hepatica

I. Fairweather, E. Hoey, M. Robinson, 2004, Parasitology Research.

Structural and Functional Relationships in the Virulence-associated Cathepsin L Proteases of the Parasitic Liver Fluke, Fasciola hepatica*

C. Craik, J. Dalton, R. Marion, 2008, Journal of Biological Chemistry.

Paramphistomosis of Ruminants: An Emerging Parasitic Disease in Europe.

Mark W Robinson, M. Robinson, Kathryn M Huson, 2017, Trends in parasitology.

Development of the vitellaria of the liver fluke, Fasciola hepatica in the rat host

J. Waite, I. Fairweather, G. Brennan, 2001, Parasitology.

Genetic manipulation of blood group carbohydrates alters development and pathfinding of primary sensory axons of the olfactory systems.

S. Domino, B. Key, J. S. St John, 2006, Developmental biology.

Exploring Evolutionary Relationships within Neodermata Using Putative Orthologous Groups of Proteins, with Emphasis on Peptidases

M. Robinson, D. Hernández-Mena, V. Caña-Bozada, 2023, Tropical medicine and infectious disease.

The cathepsin-like cysteine peptidases of trematodes of the genus Fasciola.

J. Dalton, S. O'Neill, I. Pritsch, 2019, Advances in parasitology.

The Importance of pH in Regulating the Function of the Fasciola hepatica Cathepsin L1 Cysteine Protease

J. Dalton, J. Matthews, M. Robinson, 2009, PLoS neglected tropical diseases.

Helminth pathogen cathepsin proteases: it's a family affair.

Sheila Donnelly, John P Dalton, J. Dalton, 2008, Trends in biochemical sciences.

Viral genotype correlates with distinct liver gene transcription signatures in chronic hepatitis C virus infection

D. Gatherer, J. McLauchlan, E. Aranday-Cortes, 2015, Liver international : official journal of the International Association for the Study of the Liver.

Trematode Proteomics: Recent Advances and Future Directions

M. Robinson, Adam P S Bennett, 2021, Pathogens.

Complementary transcriptomic and proteomic analyses reveal the cellular and molecular processes that drive growth and development of Fasciola hepatica in the host liver

J. Dalton, K. Cwiklinski, M. Robinson, 2021, BMC Genomics.

Unexpected Activity of a Novel Kunitz-type Inhibitor

J. Dvorak, J. Dalton, I. Tikhonova, 2016, The Journal of Biological Chemistry.

Unexpected Activity of a Novel Kunitz-Type Inhibtior: Inhibition of Cysteine Proteases but not Serine Proteases

J. Dvorak, J. Dalton, I. Tikhonova, 2016 .

The Extracellular Vesicles of the Helminth Pathogen, Fasciola hepatica: Biogenesis Pathways and Cargo Molecules Involved in Parasite Pathogenesis

J. Dalton, A. Marcilla, S. O'Neill, 2015, Molecular & Cellular Proteomics.

Helminth defence molecules—immunomodulators designed by parasites!

J. Dalton, M. Robinson, S. Donnelly, 2013, Front. Microbiol..

Fasciola hepatica virulence-associated cysteine peptidases: a systems biology perspective.

J. Dalton, P. McVeigh, A. Maule, 2012, Microbes and infection.

A Family of Helminth Molecules that Modulate Innate Cell Responses via Molecular Mimicry of Host Antimicrobial Peptides

J. Dalton, R. Norton, M. Perugini, 2011, PLoS pathogens.

Secreted cysteine proteases of the carcinogenic liver fluke, Opisthorchis viverrini: regulation of cathepsin F activation by autocatalysis and trans‐processing by cathepsin B

J. Dalton, P. Brindley, T. Laha, 2010, Cellular microbiology.

Cathepsin F Cysteine Protease of the Human Liver Fluke, Opisthorchis viverrini

A. Loukas, J. Dalton, P. Brindley, 2009, PLoS neglected tropical diseases.

Comparative analysis of the excretory-secretory proteome of the muscle larva of Trichinella pseudospiralis and Trichinella spiralis.

D. Lamont, K. Beattie, M. Robinson, 2007, International journal for parasitology.

Proteomic analysis of the excretory‐secretory proteins of the Trichinella spiralis L1 larva, a nematode parasite of skeletal muscle

M. Robinson, B. Connolly, 2005, Proteomics.

Cysteine Proteases of Pathogenic Organisms

J. Dalton, M. Robinson, 2011 .

The M17 leucine aminopeptidase of the malaria parasite Plasmodium falciparum: importance of active site metal ions in the binding of substrates and inhibitors.

J. Dalton, K. Trenholme, D. Gardiner, 2009, Biochemistry.

Transcriptome and Secretome Analysis of Intra-Mammalian Life-Stages of Calicophoron daubneyi Reveals Adaptation to a Unique Host Environment

Yongxiang Fang, T. McNeilly, S. Paterson, 2021, Molecular & cellular proteomics : MCP.

Transcriptome and Secretome Analysis of Intra-Mammalian Life-Stages of Calicophoron daubneyi Reveals Adaptation to a Unique Host Environment

Yongxiang Fang, T. McNeilly, S. Paterson, 2020, Molecular & cellular proteomics : MCP.

Role of Fasciola hepatica Small RNAs in the Interaction With the Mammalian Host

Santiago Fontenla, J. Tort, M. Robinson, 2022, Frontiers in Cellular and Infection Microbiology.

Investigation of type I interferon responses in ANCA-associated vasculitis

C. Walsh, E. Vital, C. Murphy, 2021, Scientific Reports.

The Immune Consequences of Lactate in the Tumor Microenvironment.

C. O’Farrelly, M. Robinson, C. Harmon, 2020, Advances in experimental medicine and biology.

The protein and microRNA cargo of extracellular vesicles from parasitic helminths - current status and research priorities.

A. Marcilla, P. Nejsum, J. Sotillo, 2020, International journal for parasitology.

Special considerations for studies of extracellular vesicles from parasitic helminths: A community‐led roadmap to increase rigour and reproducibility

Chelsea N. Davis, A. Loukas, E. Buzás, 2023, Journal of extracellular vesicles.

Inflammatory processes in the liver: divergent roles in homeostasis and pathology

C. O’Farrelly, M. Robinson, O. Ahmed, 2021, Cellular & Molecular Immunology.

Fasciola hepatica expresses multiple α- and β-tubulin isotypes

A. Ivens, D. Johnston, T. Feltwell, 2008, Molecular and biochemical parasitology.

The occurrence and significance of triploidy in the liver fluke, Fasciola hepatica

I. Fairweather, E. Hoey, M. Robinson, 2004, Parasitology.

Infection by the Helminth Parasite Fasciola hepatica Requires Rapid Regulation of Metabolic, Virulence, and Invasive Factors to Adjust to Its Mammalian Host

J. Dalton, S. O'Neill, P. McVeigh, 2018, Molecular & Cellular Proteomics.

Peroxiredoxin: a central player in immune modulation

J. Dalton, M. Robinson, S. Donnelly, 2010, Parasite immunology.

Fasciola gigantica: Ultrastructural cytochemistry of the tegumental surface in newly- excysted metacercariae and in vitro-penetrated juvenile flukes informs a concept of parasite defence at the interface with the host.

I. Fairweather, G. Brennan, W. Jura, 2019, Veterinary parasitology.

Cloning and analysis of a Trichinella pseudospiralis muscle larva secreted serine protease gene.

J. Appleton, K. Cwiklinski, M. Robinson, 2009, Veterinary parasitology.

Developmental Regulation and Functional Prediction of microRNAs in an Expanded Fasciola hepatica miRNome

Claire Ortiz Hill, P. McVeigh, N. Marks, 2021, bioRxiv.

The enigmatic asparaginyl endopeptidase of helminth parasites.

J. Dalton, P. Brindley, M. Robinson, 2009, Trends in parasitology.

Tracking TCRβ Sequence Clonotype Expansions during Antiviral Therapy Using High-Throughput Sequencing of the Hypervariable Region

G. Wilkie, J. Hughes, J. McLauchlan, 2016, Front. Immunol..

The cellular and molecular origins of extracellular vesicles released by the helminth pathogen, Fasciola hepatica.

M. Robinson, Nicola A M Oliver, Eduardo de la Torre-Escudero, 2020, International journal for parasitology.

Schistosome-Induced Fibrotic Disease: The Role of Hepatic Stellate Cells.

D. McManus, G. Ramm, M. Robinson, 2018, Trends in parasitology.

Synthetic peptides derived from the Schistosoma mansoni secretory protein Sm16 induce contrasting responses in hepatic stellate cells.

G. Ramm, M. Robinson, G. Gobert, 2022, Experimental parasitology.

Fasciola hepatica Extracellular Vesicles isolated from excretory-secretory products using a gravity flow method modulate dendritic cell phenotype and activity

J. Dalton, S. O'Neill, L. Joshi, 2020, PLoS neglected tropical diseases.

Lactate-Mediated Acidification of Tumor Microenvironment Induces Apoptosis of Liver-Resident NK Cells in Colorectal Liver Metastasis

L. Lynch, J. Geoghegan, D. Houlihan, 2018, Cancer Immunology Research.

Proteomics of Host-Helminth Interactions

K. Cwiklinski, M. Robinson, Krystyna Cwiklinski, 2021, Pathogens.

Insights Into Human Intrahepatic NK Cell Function From Single Cell RNA Sequencing Datasets

M. Robinson, G. Jameson, 2021, Frontiers in Immunology.

Broad Anti-Hepatitis C Virus (HCV) Antibody Responses Are Associated with Improved Clinical Disease Parameters in Chronic HCV Infection

J. McLauchlan, V. Cowton, E. Thomson, 2016, Journal of Virology.

Isolation of Secreted and Tegumental Surface Proteins from Fasciola hepatica.

M. Robinson, Eduardo de la Torre-Escudero, 2020, Methods in molecular biology.

Benzimidazole binding to Haemonchus contortus tubulin: a question of structure.

I. Fairweather, N. Mcferran, M. Robinson, 2002, Trends in Parasitology.

The parasite-derived peptide FhHDM-1 activates the PI3K/Akt pathway to prevent cytokine-induced apoptosis of β-cells

N. Braidy, M. Robinson, J. To, 2021, Journal of Molecular Medicine.

Secreted Protein Acidic and Rich in Cysteine (SPARC) Mediates Metastatic Dormancy of Prostate Cancer in Bone *

E. White, Y. Shiozawa, S. Scheuring, 2016, The Journal of Biological Chemistry.