S. Chao

发表

Minireview Transcriptional activation by the Myb proteins requires a speci¢c local promoter structure

J. Lipsick, B. Ganter, S. Chao, 1999 .

Discovery of ((4-(5-(Cyclopropylcarbamoyl)-2-methylphenylamino)-5-methylpyrrolo[1,2-f][1,2,4]triazine-6-carbonyl)(propyl)carbamoyloxy)methyl-2-(4-(phosphonooxy)phenyl)acetate (BMS-751324), a Clinical Prodrug of p38α MAP Kinase Inhibitor.

James Lin, K. McIntyre, D. Shuster, 2015, Journal of medicinal chemistry.

Interactions of endogenous and exogenous estrogenic compounds with human placental microsomal cytochrome P-450 (P-450hpm).

M. Juchau, S. Chao, 1980, Journal of steroid biochemistry.

Dual metalloprotease inhibitors: mercaptoacetyl-based fused heterocyclic dipeptide mimetics as inhibitors of angiotensin-converting enzyme and neutral endopeptidase.

N. Trippodo, H. Cheung, R. Misra, 1997, Journal of medicinal chemistry.

Catechol estrogen formation in placental and fetal tissues of humans, macaques, rats and rabbits.

S. Nelson, B. Dvorchik, M. Juchau, 1981, Developmental pharmacology and therapeutics.

Drug Metabolism by the Human Fetus

M. Juchau, S. Chao, C. Omiecinski, 1980, Clinical pharmacokinetics.

Mono-oxygenase induction in the human placenta. Interrelationships among position-specific hydroxylations of 17 beta-estradiol and benzo[a]pyrene.

M. Juchau, S. Chao, J. Namkung, 1982, Drug metabolism and disposition: the biological fate of chemicals.

Acridone-based inhibitors of inosine 5'-monophosphate dehydrogenase: discovery and SAR leading to the identification of N-(2-(6-(4-ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2- fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419).

Ping Chen, Henry H. Gu, E. Iwanowicz, 2007, Journal of medicinal chemistry.

Vicarious nucleophilic substitution of 1-benzyl-5-nitroimidazole, application to the synthesis of 6,7-dihydroimidazo[4,5-d][1,3]diazepin-8(3H)-one

Saleem Ahmad, S. Chao, John E. Tellew, 2002 .

BMS-200475, a novel carbocyclic 2′-deoxyguanosine analog with potent and selective anti-hepatitis B virus activity in vitro

O. Kocy, M. Young, R. Colonno, 1997 .

Tetrabutylammonium Pyridin-2-olate: A New Reagent for the Efficient Synthesis of N-Aryl Pyridin-2-ones

S. Chao, Bang-Chi Chen, R. Zhao, 2008 .

Stereospecific synthesis of 6,c-10-dimethyl(r-5-C1)spiro[4.5]dec-6-en-2-one and its conversion into (.+-.)-.alpha.-vetispirene

S. Chao, D. Caine, Anibal A. Boucugnani, 1976 .

Vasopeptidase inhibitors: incorporation of geminal and spirocyclic substituted azepinones in mercaptoacyl dipeptides.

N. Trippodo, E. Sieber-McMaster, J. Robl, 1999, Journal of medicinal chemistry.

Discovery of a tetrazole-based growth hormone secretagogue: 4-(hydroxybutyl)carbamic acid 2-{5-[1-(2-amino-2-methylpropionylamino)-2- benzyloxyethyl]tetrazol-1-yl}ethyl ester (BMS-317180).

W. Humphreys, K. Dickinson, R. Seethala, 2007, Journal of medicinal chemistry.

Discovery and preclinical characterization of the cyclopropylindolobenzazepine BMS-791325, a potent allosteric inhibitor of the hepatitis C virus NS5B polymerase.

Chong-Hwan Chang, M. Witmer, B. Beno, 2014, Journal of medicinal chemistry.

Enone Reduction‐Enolate Alkylation Sequence: 2‐Allyl‐3‐Methylcyclohexanone

S. Chao, Homer A. Smith, D. Caine, 2003 .

Discovery and preclinical studies of (R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5- methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy)propan- 2-ol (BMS-540215), an in vivo active potent VEGFR-2 inhibitor.

J. Fargnoli, G. Derbin, J. Barrish, 2006, Journal of medicinal chemistry.

Placental Drug Metabolism

M. Juchau, S. Chao, 1983 .

Metabolism of polycyclic aromatic hydrocarbons in placenta.

M. Juchau, S. Chao, M. Namkung, 1981, Advances in experimental medicine and biology.

Thio- and oxoflavopiridols, cyclin-dependent kinase 1-selective inhibitors: synthesis and biological effects.

W. Humphreys, J. Tokarski, L. Leith, 2000, Journal of medicinal chemistry.

Diastereoselective oxidation of sulfides to sulfoxides. Synthesis of novel C-6 sulfoxy tetrahydromevinic acids

E. Gordon, S. Chao, R. Varma, 1994 .

Synthesis of steroidal [16alpha,17-b][1,4]dioxanes.

S. Chao, R. Varma, C. Cimarusti, 1977, The Journal of organic chemistry.

Discovery of (R)-7-cyano-2,3,4, 5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine (BMS-214662), a farnesyltransferase inhibitor with potent preclinical antitumor activity.

S. Chong, J. Hunt, Soong-Hoon Kim, 2000, Journal of medicinal chemistry.

Discovery and development of 5-[(5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non-7-yl-methyl]-3-thiophenecarboxylic acid (BMS-587101)--a small molecule antagonist of leukocyte function associated antigen-1.

P. M. Davis, V. Goldfarb, D. Cheney, 2006, Journal of medicinal chemistry.

Placental mono-oxygenation: characteristics and partial purification of a hematin-activated human placental mono-oxygenase.

M. Juchau, S. Chao, M. Namkung, 1983, Drug metabolism and disposition: the biological fate of chemicals.

Modulation of monooxygenase activities by hematin and 7,8-benzoflavone in fetal tissues of rats, rabbits, and humans.

M. Juchau, S. Chao, C. Omiecinski, 1980, Developmental pharmacology and therapeutics.