M. Tsuda

发表

Report 3 : FUTURE PROSPECTS FOR TOXICOKINETICS : ITS ABILITY TO PREDICT DRUG ADVERSE EVENTS IN HUMANS ( TOXICOKINETICS)

Y. Sugiyama, Kiyomi Ito, I. Horii, 1996 .

Inhibitors of sterol biosynthesis. Carbon43 nuclear magnetic resonance studies of Sa-fluoro-5a- cholest-8(14)-en-3~-oI-15-one and related compounds

G. Schroepfer, M. Tsuda, 1981 .

Synthesis and spectral properties of 5α-cholesta-6,8,14-trien-3β-ol

E. Parish, G. Schroepfer, M. Tsuda, 1979 .

Nuclear magnetic resonance spectroscopy of sterols. 13C olefinic carbon shieldings in sterols and related cyclic compounds

G. Schroepfer, M. Tsuda, 1979 .

Degradation of polyetherurethane by subcutaneous implantation into rats. II. Changes of contact angles, infrared spectra, and nuclear magnetic resonance spectra.

T. Umemura, Y. Kurokawa, M. Tsuda, 1995, Journal of biomedical materials research.

Tobacco smoking, chewing, and snuff dipping: factors contributing to the endogenous formation of N-nitroso compounds.

Y. Kurashima, M. Tsuda, 1991, Critical reviews in toxicology.

Toxicity study of a rubber antioxidant, mixture of 2-mercaptomethylbenzimidazoles, by repeated oral administration to rats.

T. Sofuni, Y. Ohno, T. Umemura, 1999, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Liver fluke infection and cholangiocarcinoma: model of endogenous nitric oxide and extragastric nitrosation in human carcinogenesis.

H. Esumi, M. Haswell-Elkins, P. Yongvanit, 1994, Mutation research.

Relationships between the synthesis of N-nitrosodimethylamine and immune responses to chronic infection with the carcinogenic parasite, Opisthorchis viverrini, in men.

H. Bartsch, H. Esumi, M. Haswell-Elkins, 1998, Carcinogenesis.

Inhibition of sterol biosynthesis in animal cells by 14 alpha-alkyl-substituted 15-oxygenated sterols.

E. Parish, M. Tsuda, A. Kandutsch, 1979, Journal of lipid research.

Toxicity study of a rubber antioxidant, 2-mercaptobenzimidazole, by repeated oral administration to rats.

T. Umemura, Y. Kurokawa, Y. Matsushima, 1998, The Journal of toxicological sciences.

Lipopolysaccharide-associated elevation of serum and urinary nitrite/nitrate levels and hematological changes in rats.

S. Kitajima, Y. Kurokawa, Y. Matsushima, 1995, Toxicology letters.

Thiocyanate-independent nitrosation in humans with carcinogenic parasite infection.

H. Esumi, M. Haswell-Elkins, P. Yongvanit, 1996, Carcinogenesis.

Marked increase in urinary excretion of nitrate and N-nitrosothioproline in the osteogenic disordered syndrome rats, lacking ascorbic acid biosynthesis, by administration of lipopolysaccharide and thioproline.

T. Sugimura, H. Esumi, H. Ohshima, 1995, Carcinogenesis.

Marked nitrosation by stimulation with lipopolysaccharide in ascorbic acid-deficient rats.

H. Esumi, Y. Kurashima, M. Tsuda, 1990, Carcinogenesis.

L-arginine-dependent formation of N-nitrosamines by the cytosol of macrophages activated with lipopolysaccharide and interferon-gamma.

T. Sugimura, H. Esumi, H. Ohshima, 1991, Carcinogenesis.

Effects of 2,5-di(tert-butyl)-1,4-hydroquinone on intracellular free Ca2+ levels and histamine secretion in RBL-2H3 cells

J. Sawada, R. Teshima, S. Kitajima, 1995, Inflammation Research.

Sphingolipid bases. A revisitation of the O-methyl derivatives of sphingosine. Isolation and characterization of diacetate derivatives, with revised 13C nuclear magnetic resonance assignments for D-erythro-sphingosine.

W. K. Wilson, G. Schroepfer, M. Tsuda, 1995, Journal of lipid research.

Nitrite-trapping capacity of thioproline in the human body.

Y. Kurashima, M. Tsuda, 1991, IARC scientific publications.

Inhibitors of sterol synthesis. Chemical syntheses, properties and effects of 4,4-dimethyl-15-oxygenated sterols on sterol synthesis and on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured mammalian cells.

E. Parish, G. Schroepfer, M. Tsuda, 1988, Chemistry and physics of lipids.

Macrophage-mediated N-nitrosation of thioproline and proline.

Y. Kurashima, M. Tsuda, Y. Tanaka, 1989, Biochemical and biophysical research communications.

Degradation of polyetherurethane by subcutaneous implantation into rats. I. Molecular weight change and surface morphology.

T. Umemura, Y. Kurokawa, M. Tsuda, 1994, Journal of biomedical materials research.

Stereochemistry in Solution. II. Factors influencing the Relaxation Time T 1 of 14 N-Nucleus in Quaternary Amine Cations

M. Tsuda, Y. Kawazoe, M. Ohnishi, 1967 .

Catalytic Hydrogenation of Dimethylpyridine Methiodides and Stereochemistry of Hydrogenation Products

M. Tsuda, Y. Kawazoe, 1970 .

Carbon-13 nuclear magnetic resonance studies of C27 sterol precursors of cholesterol

G. Schroepfer, M. Tsuda, 1979 .

Carbon-13 nuclear magnetic resonance studies of allylic hydroxysterols. Assignment of structure of 5.alpha.-cholest-8(14)-ene-3.beta.,7.alpha.,15.alpha.-triol, an inhibitor of sterol synthesis

E. Parish, G. Schroepfer, M. Tsuda, 1979 .

Stereospecific 1,4-addition to an α,β-unsaturated steroidal epoxide: syntheses of new 15-oxygenated sterols

E. Parish, M. Tsuda, G. J. Schorepfer, 1988 .

CARBON-13 NUCLEAR MAGNETIC RESONANCE STUDIES OF ALLYLIC HYDROXYSTEROLS. ASSIGNMENT OF STRUCTURE OF 5α-CHOLEST-8(14)-ENE-3β,7α,15α-TRIOL, AN INHIBITOR OF STEROL SYNTHESIS

E. Parish, G. Schroepfer, M. Tsuda, 1979 .

Stereochemistry in Solution. III. Stereoselectivity in N-Quaternization and N-Oxygenation of α-Substituted Piperidines.

M. Tsuda, Y. Kawazoe, 1967 .

Stereochemistry in solution. I. Stereochemistry of symmetrically substituted dimethylpiperidinium salts in aqueous solutions.

M. Tsuda, Y. Kawazoe, M. Ohnishi, 1967, Chemical & pharmaceutical bulletin.

Studies on endogenous formation of N-nitroso compounds in the guinea pig supplemented with proline or thioproline and sodium nitrate.

M. Tsuda, N. Arakawa, M. Otsuka, 1992, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Inhibitors of sterol biosynthesis. Syntheses of 14α-alkyl substituted 15-oxygenated sterols

E. Parish, G. Schroepfer, M. Tsuda, 1979 .

Formation of thiazolidine-4-carboxyiic acid (thioproline), an effective nitrite-trapping agent in human body, in Parkia speciosa seeds and other edible leguminous seeds in Thailand

H. Esumi, Y. Kurashima, M. Tsuda, 1996 .

Comparative toxicokinetic study of rubber antioxidants, 2-mercaptobenzimidazole and 2-mercaptomethylbenzimidazole, by single oral administration in rats.

M. Usami, Y. Ohno, M. Tsuda, 1999, The Journal of toxicological sciences.

PROLINES IN HUMAN URINE AS MAJOR N-NITROSO COMPOUNDS

M. Tsuda, T. Hirayama, Takashi SucnviuRA, 2007 .

Effect of systemic L-arginine administration on hemodynamics and nitric oxide release in man.

H. Esumi, T. Saruta, T. Nakaki, 1992, Japanese heart journal.

Skin-sensitization potencies of the selected aldehydes in guinea pigs.

K. Isama, S. Kitajima, Y. Kurokawa, 1995 .