I. Schmitz

发表

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

YB-1 Mediates TNF-Induced Pro-Survival Signaling by Regulating NF-κB Activation

I. Lavrik, P. Mertens, J. Lindquist, 2020, Cancers.

Differential sialylation of cell surface glycoconjugates in a human B lymphoma cell line regulates susceptibility for CD95 (APO-1/Fas)-mediated apoptosis and for infection by a lymphotropic virus.

M. Peter, M. Pawlita, W. Reutter, 1999, Glycobiology.

Intracellular Staphylococcus aureus eludes selective autophagy by activating a host cell kinase

S. Foster, M. Rohde, I. Schmitz, 2016, Autophagy.

Impaired CD95-mediated Apoptosis in Autoimmunity and Occurrence of a p22 Caspase-8 Cleavage Product in JIA

T. Niehues, I. Schmitz, O. Feyen, 2008, Klinische Padiatrie.

Atypical IκB proteins – nuclear modulators of NF-κB signaling

I. Schmitz, C. Plaza-Sirvent, M. Schuster, 2013, Cell Communication and Signaling.

Atypical IκB proteins in immune cell differentiation and function.

B. Schraven, S. Kliche, I. Schmitz, 2016, Immunology letters.

Autophagy in T‐cell development, activation and differentiation

I. Schmitz, M. Schuster, Alisha W. Bronietzki, 2015, Immunology and cell biology.

c-FLIP Expression in Foxp3-Expressing Cells Is Essential for Survival of Regulatory T Cells and Prevention of Autoimmunity.

K. Schulze-Osthoff, M. Pils, I. Schmitz, 2017, Cell reports.

Differences and Similarities in TRAIL- and Tumor Necrosis Factor-Mediated Necroptotic Signaling in Cancer Cells

H. Kalthoff, D. Adam, J. Fritsch, 2016, Molecular and Cellular Biology.

Phosphorylation of Atg5 by the Gadd45β–MEKK4-p38 pathway inhibits autophagy

K. Schulze-Osthoff, F. Essmann, B. Hoffman, 2012, Cell Death and Differentiation.

Cellular FLICE-inhibitory Protein Splice Variants Inhibit Different Steps of Caspase-8 Activation at the CD95 Death-inducing Signaling Complex*

P. Krammer, A. Krueger, S. Kirchhoff, 2001, The Journal of Biological Chemistry.

Differences between CD95 type I and type II cells detected with the CD95 ligand [1]

M. Peter, P. Krammer, H. Walczak, 1999 .

Differences between CD95 type I and II cells detected with the CD95 ligand.

M. Peter, P. Krammer, H. Walczak, 1999, Cell death and differentiation.

of short-term activated T cells Upregulation of c-FLIPshort by NFAT contributes to apoptosis resistance

K. Schulze-Osthoff, I. Schmitz, M. Schuster, 2013 .

Upregulation of c-FLIP short by NFAT contributes to apoptosis resistance of short-term activated T cells

K. Schulze-Osthoff, I. Schmitz, M. Schuster, 2008 .

Up-regulation of c-FLIP short by NFAT contributes to apoptosis resistance of short-term activated T cells.

K. Schulze-Osthoff, I. Schmitz, M. Schuster, 2008, Blood.

Generation of Foxp3+CD25− Regulatory T-Cell Precursors Requires c-Rel and IκBNS

A. Visekruna, J. Huehn, I. Schmitz, 2019, Front. Immunol..

Pre-Precursors Development from Novel CD 122-Expressing Independent Steps of Regulatory T Cell Govern Common andNSB κ c-REL and

A. Visekruna, D. Bruder, J. Huehn, 2017 .

c-REL and IκBNS Govern Common and Independent Steps of Regulatory T Cell Development from Novel CD122-Expressing Pre-Precursors

A. Visekruna, D. Bruder, J. Huehn, 2017, The Journal of Immunology.

Staphylococcus aureus Alpha-Toxin Limits Type 1 While Fostering Type 3 Immune Responses

Philippe A. Robert, C. Falk, J. Huehn, 2020, Frontiers in Immunology.

Induction of apoptosis in 9-nitrocamptothecin-treated DU145 human prostate carcinoma cells correlates with de novo synthesis of CD95 and CD95 ligand and down-regulation of c-FLIP(short).

M. Peter, P. Krammer, P. Pantazis, 2001, Cancer research.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

Death-Inducing Signaling Complex Activity CD 95-Mediated Apoptosis by Blocking Correlates with Resistance Toward shortTCR-Mediated Up-Regulation of c-FLIP

P. Krammer, A. Krueger, S. Kirchhoff, 2000 .

Nfkbid Overexpression in Nonobese Diabetic Mice Elicits Complete Type 1 Diabetes Resistance in Part Associated with Enhanced Thymic Deletion of Pathogenic CD8 T Cells and Increased Numbers and Activity of Regulatory T Cells

G. Stafford, D. Serreze, I. Schmitz, 2022, The Journal of Immunology.

An IL-2-Dependent Switch Between CD95 Signaling Pathways Sensitizes Primary Human T Cells Toward CD95-Mediated Activation-Induced Cell Death 1

P. Krammer, H. Schulze‐Bergkamen, A. Krueger, 2003, The Journal of Immunology.

Cellular‐FLIP, Raji isoform (c‐FLIPR) modulates cell death induction upon T‐cell activation and infection

A. Gruber, D. Bruder, I. Schmitz, 2013, European journal of immunology.

The role of CAP3 in CD95 signaling: new insights into the mechanism of procaspase-8 activation

P. Krammer, D. Brenner, I. Lavrik, 2006, Cell Death and Differentiation.

Alternative splicing of caspase-8 mRNA during differentiation of human leukocytes.

L. Eckhart, E. Tschachler, P. Krammer, 2001, Biochemical and biophysical research communications.

Peptide-induced negative selection of thymocytes activates transcription of an NF-kappa B inhibitor.

E. Reinherz, P. Reche, E. Fiorini, 2002, Molecular cell.

Thalidomide Induces Limb Anomalies by PTEN Stabilization, Akt Suppression, and Stimulation of Caspase-Dependent Cell Death

K. Schulze-Osthoff, J. Knobloch, U. Rüther, 2012, Molecular and Cellular Biology.

IkBNS Regulates Murine Th17 Differentiation during Gut Inflammation and Infection

A. Kühl, R. Glauben, M. Lochner, 2015 .

This information is current as Infection andDifferentiation during Gut Inflammation Regulates Murine Th 17 NSB κ I

A. Kühl, R. Glauben, M. Lochner, 2015 .

Murine Staphylococcus aureus chronic infection is cured by theory-driven therapy

H. Hatzikirou, M. Meyer-Hermann, S. Khailaie, 2020, bioRxiv.

The two CD95 apoptosis signaling pathways may be a way of cells to respond to different amounts and/or forms of CD95 ligand produced in different tissues

M. Peter, P. Krammer, H. Walczak, 2000, Cell Death and Differentiation.

Caspase inhibitor zVAD.fmk reduces infarct size after myocardial ischaemia and reperfusion in rats but not in mice.

K. Zacharowski, P. Zacharowski, I. Schmitz, 2008, Resuscitation.

Toxoplasma gondii inhibits Fas/CD95‐triggered cell death by inducing aberrant processing and degradation of caspase 8

K. Schulze-Osthoff, U. Groß, I. Schmitz, 2007, Cellular microbiology.

The NF‐κB transcription factor c‐Rel controls host defense against Citrobacter rodentium

A. Visekruna, U. Steinhoff, I. Schmitz, 2019, European journal of immunology.

Type of PaperY192 within the SH2 Domain of Lck Regulates TCR Signaling Downstream of PLC-γ1 and Thymic Selection

U. Bommhardt, B. Schraven, R. Hartig, 2022, International journal of molecular sciences.

Preserved T-cell response in anti-CD20-treated multiple sclerosis patients following SARS-CoV-2 vaccination

R. Gold, I. Schmitz, K. Hellwig, 2021, Therapeutic advances in neurological disorders.

Fas/CD95-Mediated Apoptosis of Type II Cells Is Blocked by Toxoplasma gondii Primarily via Interference with the Mitochondrial Amplification Loop

O. Lytovchenko, I. Schmitz, C. Lüder, 2008, Infection and Immunity.

Up-regulation of c-FLIPS+R upon CD40 stimulation is associated with inhibition of CD95-induced apoptosis in primary precursor B-ALL.

U. Gerdemann, K. Schulze-Osthoff, G. Janka-Schaub, 2007, Blood.

Short title: CD40-mediated upregulation of c-FLIPS+R in BCP-ALL

U. Gerdemann, K. Schulze-Osthoff, H. Heine, 2007 .

Mutational analyses of c-FLIPR, the only murine short FLIP isoform, reveal requirements for DISC recruitment

R. Kühne, K. Schulze-Osthoff, C. Freund, 2008, Cell Death and Differentiation.

Reply : We would like to refer the reviewer to Reply 2 B . 4 )

A. Kühl, A. Zenclussen, É. Vivier, 2020 .

Noxa/Bcl-2 Protein Interactions Contribute to Bortezomib Resistance in Human Lymphoid Cells*

S. Kaufmann, Haiming Dai, Alyson J Smith, 2011, The Journal of Biological Chemistry.

Gene expression analysis of thymocyte selection in vivo.

E. Reinherz, I. Schmitz, L. Clayton, 2003, International immunology.

Effect of C-terminal deletions in the movement protein of cowpea chlorotic mottle virus on cell-to-cell and long-distance movement.

A. Rao, I. Schmitz, F. Osman, 1999, The Journal of general virology.

Promotion of Caspase Activation by Caspase-9-mediated Feedback Amplification of Mitochondrial Damage.

Min Chen, Jin Wang, I. Schmitz, 2012, Journal of clinical & cellular immunology.

Glutathione Dependence of Caspase-8 Activation at the Death-inducing Signaling Complex*

P. Krammer, A. Krueger, A. Wendel, 2002, The Journal of Biological Chemistry.

A Hypermorphic Nfkbid Allele Contributes to Impaired Thymic Deletion of Autoreactive Diabetogenic CD8+ T Cells in NOD Mice

V. Sarsani, A. Geurts, D. Serreze, 2018, The Journal of Immunology.

UL36 Rescues Apoptosis Inhibition and In vivo Replication of a Chimeric MCMV Lacking the M36 Gene

S. Jonjić, L. Čičin-Šain, Tihana Lenac Roviš, 2017, Front. Cell. Infect. Microbiol..

UL36 Rescues Apoptosis Inhibition and In vivo Replication of a Chimeric MCMV Lacking the M36 Gene

S. Jonjić, L. Čičin-Šain, Tihana Lenac Roviš, 2017, Front. Cell. Infect. Microbiol..

c-FLIP and CD95 signaling are essential for survival of renal cell carcinoma

I. Schmitz, C. Plaza-Sirvent, L. Schwarz, 2019, Cell Death & Disease.

Regulation of death receptor-mediated apoptosis pathways.

P. Krammer, S. Kirchhoff, I. Schmitz, 2000, The international journal of biochemistry & cell biology.

A hypermorphic Nfkbid allele represents an Idd7 locus gene contributing to impaired thymic deletion of autoreactive diabetogenic CD8+ T-cells in NOD mice

V. Sarsani, A. Geurts, D. Serreze, 2018, bioRxiv.

Molecular Mechanisms of Death‐Receptor‐Mediated Apoptosis

P. Krammer, I. Schmitz, U. Sartorius, 2001, Chembiochem : a European journal of chemical biology.

Multiple Mechanisms Mediate Resistance to Sorafenib in Urothelial Cancer

Peter Albers, Wolfgang A. Schulz, Ingo Schmitz, 2014, International journal of molecular sciences.

Regulating T cell differentiation through the polyamine spermidine.

T. Sparwasser, T. Strowig, A. Simon, 2020, The Journal of allergy and clinical immunology.

Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote TH17 differentiation

E. Kremmer, M. Heikenwalder, H. Anders, 2014, Nature Immunology.

TCR-Mediated Up-Regulation of c-FLIPshort Correlates with Resistance Toward CD95-Mediated Apoptosis by Blocking Death-Inducing Signaling Complex Activity1

P. Krammer, A. Krueger, S. Kirchhoff, 2000, The Journal of Immunology.

MAPK/ERK signaling in activated T cells inhibits CD95/Fas‐mediated apoptosis downstream of DISC assembly

V. L. Johnson, P. Krammer, J. Eriksson, 2000, The EMBO journal.

Differential Modulation of Apoptosis Sensitivity in CD95 Type I and Type II Cells*

Ingo Schmitz, S. Korsmeyer, M. Peter, 1999, The Journal of Biological Chemistry.

The Role of c-FLIP in Modulation of CD95-induced Apoptosis*

Ingo Schmitz, M. Peter, P. Krammer, 1999, The Journal of Biological Chemistry.

Snail regulates cell survival and inhibits cellular senescence in human metastatic prostate cancer cell lines

W. Schulz, I. Schmitz, Z. Soheili, 2010, Cell Biology and Toxicology.

Inhibition of autophagy through MAPK14-mediated phosphorylation of ATG5

I. Schmitz, R. Höcker, Alison S. Walker, 2013, Autophagy.

Acute cytotoxicity of MIRA-1/NSC19630, a mutant p53-reactivating small molecule, against human normal and cancer cells via a caspase-9-dependent apoptosis.

K. Schulze-Osthoff, A. Jarry, J. Mosnier, 2015, Cancer letters.

Specificity of anti-human CD95 (APO-1/Fas) antibodies.

P. Krammer, A. Krueger, S. Kirchhoff, 2002, Biochemical and biophysical research communications.

IκBNS Regulates Murine Th17 Differentiation during Gut Inflammation and Infection

A. Kühl, R. Glauben, M. Lochner, 2015, The Journal of Immunology.

Peptide-Induced Negative Selection of Thymocytes Activates Transcription of an NF-ΚB Inhibitor

E. Reinherz, P. Reche, E. Fiorini, 2002 .

A Central Role for Atg5 in Microbiota-Dependent Foxp3+ RORγt+ Treg Cell Preservation to Maintain Intestinal Immune Homeostasis

T. Strowig, M. Pils, I. Schmitz, 2021, Frontiers in Immunology.

Memantine potentiates cytarabine-induced cell death of acute leukemia correlating with inhibition of Kv1.3 potassium channels, AKT and ERK1/2 signaling

U. Bommhardt, B. Schraven, F. Heidel, 2019, Cell Communication and Signaling.

Loss of caspase-9 reveals its essential role for caspase-2 activation and mitochondrial membrane depolarization.

Ingo Schmitz, K. Schulze-Osthoff, Klaus Schulze-Osthoff, 2006, Molecular biology of the cell.

A single nucleotide polymorphism determines protein isoform production of the human c-FLIP protein.

A. Marx, A. Christians, A. Feller, 2009, Blood.

A mathematical model of the impact of insulin secretion dynamics on selective hepatic insulin resistance

M. Meyer-Hermann, D. Wirth, I. Schmitz, 2017, Nature Communications.

IκBζ Is a Transcriptional Key Regulator of CCL2/MCP-1

D. Hildebrand, E. Alexander, K. Schulze-Osthoff, 2013, The Journal of Immunology.

Molecular studies on bromovirus capsid protein. I. Characterization of cell-to-cell movement-defective RNA3 variants of brome mosaic virus.

A. Rao, I. Schmitz, 1996, Virology.

The Treg-Specific Demethylated Region Stabilizes Foxp3 Expression Independently of NF-κB Signaling

J. Huehn, S. Floess, L. Jänsch, 2014, PloS one.

Thalidomide Induces Limb Anomalies by PTEN Stabilization, Akt Suppression, and Stimulation of Caspase-Dependent Cell Death

K. Schulze-Osthoff, J. Knobloch, U. Rüther, 2007, Molecular and Cellular Biology.

SLy2 targets the nuclear SAP30/HDAC1 complex.

Simone Brandt, S. Beer-Hammer, A. Hausser, 2010, The international journal of biochemistry & cell biology.

IκB(NS) protein mediates regulatory T cell development via induction of the Foxp3 transcription factor.

A. Kühl, K. Schulze-Osthoff, K. Pfeffer, 2012, Immunity.

Peptide-Induced Negative Selection of Thymocytes Activates

E. Reinherz, P. Reche, E. Fiorini, 2002 .

Impact of SARS-CoV-2 vaccination on systemic immune responses in people living with HIV

C. Watzl, S. Pfaender, A. Reinacher-Schick, 2022, Frontiers in Immunology.

In-depth analysis of T cell immunity and antibody responses in heterologous prime-boost-boost vaccine regimens against SARS-CoV-2 and Omicron variant

U. Stervbo, N. Babel, M. Hoffmann, 2022, Frontiers in Immunology.

Different forms of cell death induced by putative BCL2 inhibitors

G M Cohen, G. Cohen, M. Dyer, 2009, Cell Death and Differentiation.

c-FLIP is crucial for IL-7/IL-15-dependent NKp46+ ILC development and protection from intestinal inflammation in mice

A. Kühl, A. Zenclussen, É. Vivier, 2020, Nature Communications.

Autophagy—A Story of Bacteria Interfering with the Host Cell Degradation Machinery

I. Schmitz, S. Mühlen, Anna K Riebisch, 2021, Pathogens.

1 I κ BNS protein mediates regulatory T cell development via induction of the Foxp 3 transcription factor

A. Kühl, K. Schulze-Osthoff, K. Pfeffer, 2013 .

Gadd45 proteins in immunity.

I. Schmitz, 2013, Advances in experimental medicine and biology.

Novel Insights into YB-1 Signaling and Cell Death Decisions

P. Mertens, J. Lindquist, I. Schmitz, 2021, Cancers.

Death Receptor-Induced Signaling Pathways Are Differentially Regulated by Gamma Interferon Upstream of Caspase 8 Processing

K. Schulze-Osthoff, H. Wajant, O. Dittrich‐Breiholz, 2005, Molecular and Cellular Biology.

Constitutive expression of murine c-FLIPR causes autoimmunity in aged mice

F. Neff, M. Pils, I. Schmitz, 2014, Cell Death and Disease.

CD95 ligand mediates T-cell receptor-induced apoptosis of a CD4+ CD8+ double positive thymic lymphoma

K. Schulze-Osthoff, I. Schmitz, C. Meyer, 2006, Oncogene.

Controlled functional zonation of hepatocytes in vitro by engineering of Wnt signalling.

H. Hauser, T. Pietschmann, D. Wirth, 2020, ACS synthetic biology.

A mathematical model of the impact of insulin secretion dynamics on selective hepatic insulin resistance

M. Meyer-Hermann, D. Wirth, I. Schmitz, 2017, Nature Communications.

In silico predicted therapy against chronic Staphylococcus aureus infection leads to bacterial clearance in vivo

H. Hatzikirou, M. Meyer-Hermann, S. Khailaie, 2022, iScience.

Deletions in the conserved amino-terminal basic arm of cucumber mosaic virus coat protein disrupt virion assembly but do not abolish infectivity and cell-to-cell movement.

A. Rao, I. Schmitz, 1998, Virology.

Cell-to-cell transport of movement-defective cucumber mosaic and tobacco mosaic viruses in transgenic plants expressing heterologous movement protein genes.

J. Dodds, B. Cooper, R. Beachy, 1996, Virology.

The role of c-FLIP splice variants in urothelial tumours

W. Schulz, L. Brockmann, C. Hader, 2011, Cell Death and Disease.

Glutathione depletion regulates both extrinsic and intrinsic apoptotic signaling cascades independent from multidrug resistance protein 1

C. Bortner, J. Cidlowski, R. Franco, 2013, Apoptosis.

Loss of Caspase-9 Provides Genetic Evidence for the Type I/II Concept of CD95-mediated Apoptosis*

K. Schulze-Osthoff, I. Schmitz, A. K. Samraj, 2006, Journal of Biological Chemistry.

Resistance of Short Term Activated T Cells to CD95-Mediated Apoptosis Correlates with De Novo Protein Synthesis of c-FLIPshort1

P. Krammer, A. Krueger, S. Kirchhoff, 2004, The Journal of Immunology.

Immunophenotyping of Monocyte Migration Markers and Therapeutic Effects of Selenium on IL-6 and IL-1β Cytokine Axes of Blood Mononuclear Cells in Preoperative and Postoperative Coronary Artery Disease Patients

K. Borucki, I. Schmitz, J. Wippermann, 2023, International journal of molecular sciences.

Protein Synthesis of c-FLIP DeCD 95-Mediated Apoptosis Correlates with Resistance of Short Term Activated T Cells to

P. Krammer, A. Krueger, S. Kirchhoff, 2004 .

The active caspase-8 heterotetramer is formed at the CD95 DISC

A Krueger, P. Krammer, I. Lavrik, 2003, Cell Death and Differentiation.

Essential role of IκBNS for in vivo CD4+ T‐cell activation, proliferation, and Th1‐cell differentiation during Listeria monocytogenes infection in mice

D. Bruder, I. Schmitz, A. Jeron, 2019, European journal of immunology.

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

Memantine potentiates cytarabine-induced cell death of acute leukemia correlating with inhibition of Kv1.3 potassium channels, AKT and ERK1/2 signaling

U. Bommhardt, B. Schraven, F. Heidel, 2019, Cell Communication and Signaling.

Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652

Lee, Duchen, Izzo, 2016 .

Immune response in ofatumumab treated multiple sclerosis patients after SARS-CoV-2 vaccination

R. Gold, C. Watzl, S. Pfaender, 2022, Frontiers in Immunology.

IκBNS-deficiency protects mice from fatal Listeria monocytogenes infection by blunting pro-inflammatory signature in Ly6Chigh monocytes and preventing exaggerated innate immune responses

D. Bruder, I. Schmitz, A. Jeron, 2022, Frontiers in Immunology.