E. Mulder

发表

Androgen receptors in endocrine‐therapy‐resistant human prostate cancer

T. H. van der Kwast, J. Trapman, W. Boersma, 1991, International journal of cancer.

Hormone-induced dissociation of the androgen receptor-heat-shock protein complex: use of a new monoclonal antibody to distinguish transformed from nontransformed receptors.

T. H. van der Kwast, J. Veldscholte, J. Grootegoed, 1992, Biochemistry.

A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens.

G. Jenster, J. Veldscholte, J. Trapman, 1990, Biochemical and biophysical research communications.

Effects of antiandrogens on transformation and transcription activation of wild-type and mutated (LNCaP) androgen receptors

J. Veldscholte, E. Mulder, C. Berrevoets, 1993, The Journal of Steroid Biochemistry and Molecular Biology.

Androgen‐dependent growth regulation of and release of specific protein(s) by the androgen receptor containing human prostate tumor cell line LNCaP

E. Berns, E. Mulder, W. de Boer, 1986 .

Characterization of androgen receptors in a transplantable human prostatic adenocarcinoma (PC‐82)

A. Brinkmann, G. J. van Steenbrugge, G. Kuiper, 1987, The Prostate.

Chapter 4 Characterization, assay and purification of steroid receptors

M. Blankenstein, E. Mulder, 1988 .

Antiproliferative effects of suramin on androgen responsive tumour cells.

J. Foekens, E. Berns, D. Lamb, 1990, European journal of cancer.

Studies on the Human Prostatic Cell Line LNCaP Cancer

J. Veldscholte, E. Mulder, C. Berrevoets, 1994 .

Studies on the human prostatic cancer cell line LNCaP

J. Veldscholte, E. Mulder, C. Berrevoets, 1994, The Journal of Steroid Biochemistry and Molecular Biology.

Effect of culture conditions on androgen sensitivity of the human prostatic cancer cell line LNCaP

M. Blankenstein, G. J. van Steenbrugge, E. Mulder, 1993, The Prostate.

Presence of progesterone receptors and absence of oestrogen receptors in human intracranial meningioma cytosols.

M. Blankenstein, S. Lamberts, E. Mulder, 1983, European journal of cancer & clinical oncology.

Androgen receptor heterogeneity in human prostatic carcinomas visualized by immunohistochemistry

T. H. van der Kwast, J. Trapman, A. Brinkmann, 1990, The Journal of pathology.

Cloning, structure and expression of a cDNA encoding the human androgen receptor.

J. A. van der Korput, J. Trapman, A. Brinkmann, 1988, Biochemical and biophysical research communications.

Unusual specificity of the androgen receptor in the human prostate tumor cell line LNCaP: high affinity for progestagenic and estrogenic steroids.

J. Veldscholte, J. Trapman, E. Mulder, 1990, Biochimica et biophysica acta.

Mechanism of androgen action: recent observations on the domain structure of androgen receptors and the induction of EGF-receptors by androgens in prostate tumor cells.

A. Brinkmann, G. Kuiper, A. Schuurmans, 1989, Journal of steroid biochemistry.

Functional in vivo interaction between the amino-terminal, transactivation domain and the ligand binding domain of the androgen receptor.

J. Trapman, A. Brinkmann, E. Mulder, 1997, Biochemistry.

Mechanism of antiandrogen action: Conformational changes of the receptor

E. Mulder, C. Kuil, Eppo Mulder, 1994, Molecular and Cellular Endocrinology.

A receptor for testosterone in mature rat testes

E. Mulder, H. van der Molen, M. Peters, 1974, FEBS letters.

Characterization of a nuclear receptor for testosterone in seminiferous tubules of mature rat testes

E. Mulder, H. J. Molen, M. Peters, 1975, Molecular and Cellular Endocrinology.

Androgens and transforming growth factor β modulate the growth response to epidermal growth factor in human prostatic tumor cells (LNCaP)

A. Schuurmans, E. Mulder, J. Bolt, 1988, Molecular and Cellular Endocrinology.

Analysis of steroid- and DNA-binding domains of the calf uterine androgen receptor by limited proteolysis.

A. Brinkmann, G. Kuiper, E. Mulder, 1987, Journal of steroid biochemistry.

Characterization of the calf uterine androgen receptor and its activation to the deoxyribonucleic acid-binding state.

A. Brinkmann, E. Mulder, M. Lindh, 1986, Endocrinology.

Characterization of androgen receptors after photoaffinity labelling with [3H]methyltrienolone (R1881).

A. Brinkmann, G. J. van Steenbrugge, G. Kuiper, 1986, Journal of steroid biochemistry.

Characterization of steroid hormone receptors with ion-exchange fast protein liquid chromatography.

A. Brinkmann, E. Mulder, J. Bolt-de Vries, 1985, Journal of steroid biochemistry.

Fluorescent androgen derivatives do not discriminate between androgen receptor‐positive and ‐negative human tumor cell lines

E. Berns, E. Mulder, F. Rommerts, 1984, The Prostate.

Interaction of rat prostate androgen receptors with polynucleotides, RNA, DNA and cloned DNA fragments.

A. Brinkmann, M. Parker, A. Vrij, 1984, Biochimica et biophysica acta.

DNA and ribonucleotide binding characteristics of two forms of the androgen receptor from rat prostates.

A. Brinkmann, A. Vrij, E. Mulder, 1983, Biochemical and biophysical research communications.

Extraction of nuclear androgen receptors from rat prostate with different reagents

J. Foekens, E. Mulder, L. Vrij, 1981, Molecular and Cellular Endocrinology.

Inhibition of nucleic acid and chromatin binding of the rat prostate androgen receptor by pyridoxal phosphate, heparin and cibacron blue

J. Foekens, E. Mulder, L. Vrij, 1980, Steroids.

Testicular estradiol receptors in the rat.

E. Mulder, H. van der Molen, W. de Boer, 1974, Current topics in molecular endocrinology.

Binding of oestradiol by the nuclear fraction of rat testis interstitial tissue

A. Brinkmann, E. Mulder, H. van der Molen, 1973, FEBS letters.

Absence of a nuclear androgen receptor in isolated germinal cells of rat testis

J. Grootegoed, E. Mulder, F. Rommerts, 1977, Molecular and Cellular Endocrinology.

Androgen receptors in testis tissue enriched in Sertoli cells.

E. Mulder, H. van der Molen, M. Peters, 1975, Current topics in molecular endocrinology.

Androgens and androgen-receptors in prostate tissue from patients with benign prostatic hyperplasia: Effects of cyproterone acetate

E. Mulder, F. H. Jong, J. Blom, 1992, The Journal of Steroid Biochemistry and Molecular Biology.

Differential effects of molybdate on the hydrodynamic and DNA-binding properties of the non-activated and activated forms of the androgen receptor in calf uterus.

A. Brinkmann, E. Mulder, W. de Boer, 1986, Biochimica et biophysica acta.

Nuclear androgen receptors in human prostatic tissue. Extraction with heparin and estimation of the number of binding sites with different methods.

J. Foekens, F. Schröder, M. Blankenstein, 1981, Clinica chimica acta; international journal of clinical chemistry.

A comparison of heparin agarose and DNA cellulose for the characterization and partial purification of androgen receptors from rat prostate

J. Foekens, E. Mulder, van der Molen, 1979, FEBS Letters.

Further characterization of the effects of hypophysectomy, FSH and estrogen on LH stimulation of testosterone production in leydig cells isolated from immature rats

E. Mulder, H. J. Molen, W. V. Beurden, 1978, Steroids.

Hormonal regulation of lh stimulation of testosterone production in isolated leydig cells of immature rats: The effect of hypophysectomy, fsh, and estradiol-17β

E. Mulder, F. H. Jong, H. J. Molen, 1976, Steroids.

Biochemical Functions of Isolated Interstitial Tissue and Seminiferous Tubules from Rat Testis

A. Brinkmann, E. Mulder, F. H. Jong, 1973 .

Regulation of growth of LNCaP human prostate tumor cells by growth factors and steroid hormones

J. Veldscholte, A. Schuurmans, E. Mulder, 1991, The Journal of Steroid Biochemistry and Molecular Biology.

Search for estrogen receptors in human meningioma tissue sections with a monoclonal antibody against the human estrogen receptor.

M. Blankenstein, J. Thijssen, E. Mulder, 1986, Cancer research.

Androgen receptor specificity and growth response of a human cell line (NHIK 3025)

K. Østgaard, E. Mulder, H. J. Molen, 1978, Molecular and Cellular Endocrinology.

An Oestradiol receptor in rat testis interstitial tissue

A. Brinkmann, E. Mulder, H. van der Molen, 1972, FEBS letters.

Ligand-induced Conformational Alterations of the Androgen Receptor Analyzed by Limited Trypsinization

E. Mulder, C. Berrevoets, C. Kuil, 1995, The Journal of Biological Chemistry.

Anti-androgens and the mutated androgen receptor of LNCaP cells: differential effects on binding affinity, heat-shock protein interaction, and transcription activation.

J. Veldscholte, J. Grootegoed, A. Brinkmann, 1992, Biochemistry.

Androgen receptor expression in human tissues: an immunohistochemical study.

T. H. van der Kwast, T. Kwast, J. Trapman, 1991, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

The androgen receptor in LNCaP cells contains a mutation in the ligand binding domain which affects steroid binding characteristics and response to antiandrogens

G. Jenster, J. Veldscholte, J. Trapman, 1992, The Journal of Steroid Biochemistry and Molecular Biology.

The testis: biochemical actions of trophic hormones and steroids on steroid production and spermatogenesis.

M. Blankenstein, F. de Jong, J. Grootegoed, 1979, Journal of steroid biochemistry.

Isolation and characterization of 17 -hydroxy steroid dehydrogenase from human erythrocytes.

E. Mulder, H. van der Molen, G. Lamers-stahlhofen, 1972, The Biochemical journal.

Metabolism of free and conjugated steroids by intact and hemolysed mammalian erythrocytes.

E. Mulder, H. van der Molen, G. Lamers-stahlhofen, 1972, Biochimica et biophysica acta.

Kinetics of in vitro binding of oestradiol in subcellular fractions of testicular and uterine tissue; characterization of oestradiol binding in testicular nuclei.

E. Mulder, J. D. de Vries, H. van der Molen, 1977, Journal of steroid biochemistry.

Characterization and partial purification of androgen receptors from ram seminal vesicles

J. Foekens, R. Peerbolte, E. Mulder, 1981, Molecular and Cellular Endocrinology.

The effect of estrogens on luteinizing hormone plasma levels and on testosterone production in intact and hypophysectomized rats.

F. de Jong, E. Mulder, H. van der Molen, 1977, Endocrinology.

Epitope prediction and confirmation for the human androgen receptor: generation of monoclonal antibodies for multi-assay performance following the synthetic peptide strategy.

T. H. van der Kwast, T. Kwast, J. Trapman, 1991, Biochimica et biophysica acta.

HIGH AFFINITY BINDING OF OESTRADIOL BY RAT TESTIS INTERSTITIAL TISSUE AND BY SEVERAL OTHER TISSUES OF THE MALE RAT

A. Brinkmann, E. Mulder, H. J. Molen, 1974 .

Model studies with erythrocytes on the initial steps of cellular uptake and binding of steroids.

A. Brinkmann, E. Mulder, H. van der Molen, 1972, Journal of steroid biochemistry.

The human androgen receptor: domain structure, genomic organization and regulation of expression.

J. A. van der Korput, J. Trapman, A. Brinkmann, 1989, Journal of steroid biochemistry.

Androgen receptor abnormalities

J. Trapman, C. Ris-Stalpers, A. Brinkmann, 1991, The Journal of Steroid Biochemistry and Molecular Biology.

Androgens stimulate both growth rate and epidermal growth factor receptor activity of the human prostate tumor cell LNCaP

A. Schuurmans, E. Mulder, J. Bolt, 1988, The Prostate.

Effects of oestradiol-18beta, hypophysectomy and age on cytoplasmic oestradiol-17beta receptor sites in rat testis interstitial tissue.

E. Mulder, H. van der Molen, W. de Boer, 1976, The Journal of endocrinology.

Changes of oestrogen receptor levels in Leydig cells from mice and rats during culture.

E. Berns, A. Brinkmann, E. Mulder, 1985, Journal of steroid biochemistry.

Cyproterone acetate prevents translocation of the androgen receptor in the rat prostate

A. Brinkmann, E. Mulder, H. J. Molen, 1983, Molecular and Cellular Endocrinology.

Photoaffinity labelling of androgen receptors with 17β-hydroxy-17α-[3H]methyl-4,9,11-estratrien-3-one

A. Brinkmann, G. Kuiper, E. Mulder, 1985 .

Interaction between steroids and membranes, uptake of steroids and steroid sulphates by resealed erythrocyte ghosts.

E. Mulder, H. van der Molen, G. Lamers-stahlhofen, 1973, Journal of steroid biochemistry.

Estimation of total oestrogen receptors in DMBA-induced rat mammary tumors by exchange of nuclear bound ligand at low temperature; a comparison with rat uterus.

M. Blankenstein, E. Mulder, H. van der Molen, 1980, Journal of steroid biochemistry.

Stimulatory effects of antiandrogens on LNCaP human prostate tumor cell growth, EGF-receptor level and acid phosphatase secretion

J. Veldscholte, A. Schuurmans, E. Mulder, 1990, The Journal of Steroid Biochemistry and Molecular Biology.

Interaction of steroids with human red blood cells.

A. Brinkmann, E. Mulder, H. van der Molen, 1970, Annales d'endocrinologie.

Structure and function of the androgen receptor

J. Trapman, A. Brinkmann, G. Kuiper, 2004, Urological Research.

Oestrogen receptors in rat mammary tissue and plasma concentrations of prolactin during mammary carcinogenesis induced by oestrogen and ionizing radiation.

M. Blankenstein, J. Broerse, E. Mulder, 1981, The Journal of endocrinology.

Regulation of growth and epidermal growth factor receptor levels of LNCaP prostate tumor cells by different steroids

A. Schuurmans, E. Mulder, J. Bolt, 1988, International journal of cancer.

Fluorescent ligands, used in histocytochemistry, do not discriminate between estrogen receptor-positive and receptor-negative human tumor cell lines

E. Berns, E. Mulder, F. Rommerts, 2005, Breast Cancer Research and Treatment.

Purification of the intact monomeric 110 kDa form of the androgen receptor from calf uterus to near homogeneity.

A. Brinkmann, D. van Loon, E. Mulder, 1988, Biochimica et biophysica acta.

Purification of the androgen receptor of sheep seminal vesicles.

J. Foekens, E. Mulder, H. van der Molen, 1982, Biochemical and biophysical research communications.

The androgen receptor: Functional structure and expression in transplanted human prostate tumors and prostate tumor cell lines

J. Trapman, C. Ris-Stalpers, A. Brinkmann, 1990, The Journal of Steroid Biochemistry and Molecular Biology.

Deoxyribonucleic acid-binding ability of androgen receptors in whole cells: implications for the actions of androgens and antiandrogens.

E. Mulder, C. Kuil, 1996, Endocrinology.

High-affinity binding of oestradiol-17beta by cytosols from testis interstitial tissue, pituitary, adrenal, liver and accessory sex glands of the male rat.

A. Brinkmann, E. Mulder, H. van der Molen, 1974, The Biochemical journal.

Rapid and sensitive detection of oestrogen receptors in cells and tissue sections by autoradiography with125I-oestradiol

E. Berns, E. Mulder, F. Rommerts, 1985, The Histochemical Journal.

Comparative study of nuclear binding sites for oestradiol in rat testicular and uterine tissue. Determination of low amounts of specific binding site by an [3H] oestradiol-exchange method.

E. Mulder, J. D. de Vries, H. van der Molen, 1977, The Biochemical journal.

In situ photolabelling of the human androgen receptor.

A. Brinkmann, G. Kuiper, E. Mulder, 1988, Journal of steroid biochemistry.

The human androgen receptor: Structure/function relationship in normal and pathological situations

G. Jenster, J. Veldscholte, J. Trapman, 1992, The Journal of Steroid Biochemistry and Molecular Biology.

Characterization of polyclonal antibodies against the N-terminal domain of the human androgen receptor

T. Kwast, J. Trapman, J. Winter, 1989, Molecular and Cellular Endocrinology.

Characterization of Steroid Receptors Using Ion Exchange Fast Protein Liquid Chromatography (FPLC)

A. Brinkmann, E. Mulder, H. J. Molen, 1985 .

Androgen receptor-mediated growth and epidermal growth factor receptor induction in the human prostate cell line LNCaP.

A. Schuurmans, E. Mulder, J. Bolt, 1989, Urologia internationalis.

Androgen-dependent growth regulation of and release of specific protein(s) by the androgen receptor containing human prostate tumor cell line LNCaP.

E. Berns, E. Mulder, W. Boer, 1987, The Prostate.

Rapid and sensitive detection of oestrogen receptors in cells and tissue sections by autoradiography with 125I-oestradiol.

E. Berns, E. Mulder, F. Rommerts, 1985, The Histochemical journal.