A. Robertson

发表

Impaired angiogenesis in SHR is associated with decreased KDR and MT1-MMP expression.

J. Keiser, He Wang, B. Olszewski, 2004, Biochemical and biophysical research communications.

A mouse anti-myostatin antibody increases muscle mass and improves muscle strength and contractility in the mdx mouse model of Duchenne muscular dystrophy and its humanized equivalent, domagrozumab (PF-06252616), increases muscle volume in cynomolgus monkeys

Mark Johnson, P. Bansal, A. Robertson, 2017, Skeletal Muscle.

Pyrazole inhibitors of HMG-CoA reductase: an attempt to dramatically reduce synthetic complexity through minimal analog re-design.

B. Tait, M. Kowala, G. Lu, 2007, Bioorganic & medicinal chemistry letters.

Increased revascularization efficacy after administration of an adenovirus encoding VEGF121

I. Kovesdi, D. Gordon, W. Rosebury, 2004, Gene Therapy.

Discovery of pyrrole-based hepatoselective ligands as potent inhibitors of HMG-CoA reductase.

G. Lu, J. Pfefferkorn, Chulho Choi, 2007, Bioorganic & medicinal chemistry.

Design and synthesis of hepatoselective, pyrrole-based HMG-CoA reductase inhibitors.

G. Lu, J. Pfefferkorn, M. Harris, 2007, Bioorganic & medicinal chemistry letters.

Inhibition of Sphingomyelin Synthesis Reduces Atherogenesis in Apolipoprotein E–Knockout Mice

M. Rekhter, R. Panek, S. Karathanasis, 2004, Circulation.

Design and synthesis of novel, conformationally restricted HMG-CoA reductase inhibitors.

Yuntao Song, Bruce Auerbach, Lisa Dillon, 2007, Bioorganic & medicinal chemistry letters.

Discovery of novel hepatoselective HMG-CoA reductase inhibitors for treating hypercholesterolemia: a bench-to-bedside case study on tissue selective drug distribution.

Bo Feng, David B Duignan, Bruce Auerbach, 2011, Bioorganic & medicinal chemistry letters.

Hepatoselectivity of statins: design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors.

Yuntao Song, Bruce Auerbach, Lisa Dillon, 2008, Bioorganic & medicinal chemistry letters.

CCR2 receptor blockade alters blood monocyte subpopulations but does not affect atherosclerotic lesions in apoE(-/-) mice.

A. Kalgutkar, D. Knight, R. Gladue, 2010, Atherosclerosis.

A mouse anti-myostatin antibody increases muscle mass and improves muscle strength and contractility in the mdx mouse model of Duchenne muscular dystrophy and its humanized equivalent, domagrozumab (PF-06252616), increases muscle volume in cynomolgus monkeys

Mark Johnson, P. Bansal, A. Robertson, 2017, Skeletal Muscle.

Modulation of lipoprotein metabolism by inhibition of sphingomyelin synthesis in ApoE knockout mice.

M. Rekhter, R. Panek, S. Karathanasis, 2006, Atherosclerosis.

Delayed angiogenesis in aging rats and therapeutic effect of adenoviral gene transfer of VEGF.

J. Keiser, I. Kovesdi, D. Gordon, 2004, International journal of molecular medicine.

Substituted pyrazoles as hepatoselective HMG-CoA reductase inhibitors: discovery of (3R,5R)-7-[2-(4-fluoro-phenyl)-4-isopropyl-5-(4-methyl-benzylcarbamoyl)-2H-pyrazol-3-yl]-3,5-dihydroxyheptanoic acid (PF-3052334) as a candidate for the treatment of hypercholesterolemia.

Bruce Auerbach, Lisa Dillon, Jeffrey A Pfefferkorn, 2008, Journal of medicinal chemistry.