A. Mohammad

发表

Brain distribution of a panel of EGFR inhibitors using cassette-dosing in wild-type and Abcb1/Abcg2 deficient mice

Minjee Kim, W. Elmquist, Janice K. Laramy, 2019 .

Brain Distribution of a Panel of Epidermal Growth Factor Receptor Inhibitors Using Cassette Dosing in Wild-Type and Abcb1/Abcg2-Deficient Mice

J. Sarkaria, Minjee Kim, W. Elmquist, 2019, Drug Metabolism and Disposition.

Central Nervous System Distribution of an Opioid Agonist Combination with Synergistic Activity

Minjee Kim, G. Wilcox, W. Elmquist, 2021, The Journal of Pharmacology and Experimental Therapeutics.

NKTR-102 Efficacy versus irinotecan in a mouse model of brain metastases of breast cancer

P. Lockman, U. Hoch, A. Mohammad, 2015, BMC Cancer.

Alterations in Pericyte Subpopulations Are Associated with Elevated Blood–Tumor Barrier Permeability in Experimental Brain Metastasis of Breast Cancer

S. Steinberg, P. Brastianos, P. Steeg, 2016, Clinical Cancer Research.

Molecular determinants of blood-brain barrier permeation.

W. Geldenhuys, P. Lockman, A. Mohammad, 2015, Therapeutic delivery.

Drug resistance occurred in a newly characterized preclinical model of lung cancer brain metastasis

P. Lockman, A. Mohammad, M. Pinti, 2019, BMC Cancer.

Abstract P1-12-05: Etirinotecan pegol: Survival advantage over standard of care drugs in a model of brain metastases of breast cancer

P. Lockman, U. Hoch, A. Mohammad, 2017 .

Semi-automated rapid quantification of brain vessel density utilizing fluorescent microscopy

P. Lockman, A. Mohammad, M. Nounou, 2016, Journal of Neuroscience Methods.

Activation of STAT3 through combined SRC and EGFR signaling drives resistance to a mitotic kinesin inhibitor in glioblastoma

Lauren E. Stopfer, S. Rosenfeld, P. Canoll, 2022, Cell reports.

A mouse Model of Focal Vascular Injury Induces Astrocyte Reactivity, Tau Oligomers, and Aberrant Behavior

C. Rosen, B. Lucke-Wold, J. Huber, 2017, Archives of neuroscience.

Influence of transporters in treating cancers in the CNS

Minjee Kim, Gautham Gampa, W. Elmquist, 2020 .

Liposomal Irinotecan Accumulates in Metastatic Lesions, Crosses the Blood-Tumor Barrier (BTB), and Prolongs Survival in an Experimental Model of Brain Metastases of Triple Negative Breast Cancer

Bart S. Hendriks, Chris E. Adkins, Paul R. Lockman, 2018, Pharmaceutical Research.

Investigational chemotherapy and novel pharmacokinetic mechanisms for the treatment of breast cancer brain metastases

Richard L. Nolan, B. Lucke-Wold, P. Lockman, 2018, Pharmacological research.

P-glycoprotein mediated efflux limits substrate and drug uptake in a preclinical brain metastases of breast cancer model

V. Manda, P. Lockman, A. Mohammad, 2013, Front. Pharmacol..

Targeting the Blood-Brain Barrier to Prevent Sepsis-Associated Cognitive Impairment

W. Geldenhuys, B. Lucke-Wold, S. Benkovic, 2019, Journal of central nervous system disease.

Quantitative Fluorescence Microscopy Measures Vascular Pore Size in Primary and Metastatic Brain Tumors.

P. Lockman, A. Mohammad, R. K. Mittapalli, 2017, Cancer research.

Overcoming the acquired resistance to gefitinib in lung cancer brain metastasis in vitro and in vivo

P. Lockman, A. Mohammad, P. Saralkar, 2021, Archives of Toxicology.

A Novel Preclinical Method to Quantitatively Evaluate Early-Stage Metastatic Events at the Murine Blood–Brain Barrier

P. Lockman, A. Mohammad, M. Nounou, 2014, Cancer Prevention Research.

Brain Distribution and Active Efflux of Three panRAF Inhibitors: Considerations in the Treatment of Melanoma Brain Metastases

J. Sarkaria, Minjee Kim, Gautham Gampa, 2019, The Journal of Pharmacology and Experimental Therapeutics.

Abstract 1388: Inhibition of VEGF and angiopoietin-2 to reduce brain metastases of breast cancer burden

P. Lockman, A. Mohammad, M. Nounou, 2015 .

Enhancing Brain Retention of a KIF11 Inhibitor Significantly Improves its Efficacy in a Mouse Model of Glioblastoma

J. Sarkaria, S. Rosenfeld, J. Crish, 2020, Scientific Reports.

Permeability changes and effect of chemotherapy in brain adjacent to tumor in an experimental model of metastatic brain tumor from breast cancer

P. Lockman, A. Mohammad, C. Adkins, 2018, BMC Cancer.

Characterization of passive permeability at the blood–tumor barrier in five preclinical models of brain metastases of breast cancer

P. Lockman, A. Mohammad, Afroz S. Mohammad, 2016, Clinical & Experimental Metastasis.

Novel treatment strategies for brain tumors and metastases.

M. Wen, A. El-Kamel, P. Lockman, 2014, Pharmaceutical patent analyst.

Enhancing Brain Retention of a KIF11 Inhibitor Significantly Improves its Efficacy in a Mouse Model of Glioblastoma

J. Sarkaria, S. Rosenfeld, J. Crish, 2019, Scientific Reports.

Brain distribution of berzosertib: an ATR inhibitor for the treatment of glioblastoma.

J. Sarkaria, R. Bindra, Minjee Kim, 2021, The Journal of pharmacology and experimental therapeutics.

Factors Influencing Luciferase-Based Bioluminescent Imaging in Preclinical Models of Brain Tumor

J. Sarkaria, Minjee Kim, Shuangling Zhang, 2021, Drug Metabolism and Disposition.

High-dose MTX110 (soluble panobinostat) safely administered into the fourth ventricle in a nonhuman primate model.

Christopher F. Janssen, W. Elmquist, A. Mohammad, 2020, Journal of neurosurgery. Pediatrics.

Characterization of passive permeability at the blood–tumor barrier in five preclinical models of brain metastases of breast cancer

P. Lockman, A. Mohammad, Tori B. Terrell-Hall, 2016, Clinical and Experimental Metastasis.

Brain Distribution of Berzosertib: An Ataxia Telangiectasia and Rad3-Related Protein Inhibitor for the Treatment of Glioblastoma

J. Sarkaria, R. Bindra, Minjee Kim, 2021, Journal of Pharmacology and Experimental Therapeutics.

Permeability changes and effect of chemotherapy in brain adjacent to tumor in an experimental model of metastatic brain tumor from breast cancer

P. Lockman, A. Mohammad, C. Adkins, 2018, BMC Cancer.