J. Arnold

发表

The multidrug transporter ABCG2 (BCRP) is inhibited by plant‐derived cannabinoids

J. Allen, M. Holland, D. Lau, 2007, British journal of pharmacology.

Interactions between cannabidiol and Δ9‐tetrahydrocannabinol in modulating seizure susceptibility and survival in a mouse model of Dravet syndrome

I. McGregor, J. Arnold, L. Anderson, 2020, British journal of pharmacology.

Enhanced Brain Disposition and Effects of Δ9-Tetrahydrocannabinol in P-Glycoprotein and Breast Cancer Resistance Protein Knockout Mice

A. Boucher, J. Arnold, A. Spiro, 2012, PloS one.

ABC transporters P-gp and Bcrp do not limit the brain uptake of the novel antipsychotic and anticonvulsant drug cannabidiol in mice

I. McGregor, J. Arnold, Kong M. Li, 2016, PeerJ.

Partial genetic deletion of neuregulin 1 and adolescent stress interact to alter NMDA receptor binding in the medial prefrontal cortex

M. Bennett, J. Arnold, Tariq W. Chohan, 2014, Front. Behav. Neurosci..

Why sigma-1 receptor dysfunction might confer vulnerability to cannabis-induced psychosis.

J. Arnold, 2014, The international journal of neuropsychopharmacology.

The Heat Sensing Trpv1 Receptor Is Not a Viable Anticonvulsant Drug Target in the Scn1a +/− Mouse Model of Dravet Syndrome

J. Arnold, J. Kearney, L. Anderson, 2021, Frontiers in Pharmacology.

Analysis of Cannabis Seizures in NSW, Australia: Cannabis Potency and Cannabinoid Profile

I. McGregor, W. Swift, J. Arnold, 2013, PloS one.

The response of neuregulin 1 mutant mice to acute restraint stress

A. Sainsbury, E. Yulyaningsih, R. Chesworth, 2012, Neuroscience Letters.

Seeing through the smoke: Human and animal studies of cannabis use and endocannabinoid signalling in corticolimbic networks

Wendy K. Adams, C. Hillard, S. Laviolette, 2017, Neuroscience & Biobehavioral Reviews.

The anticonvulsant zonisamide positively modulates recombinant and native glycine receptors at clinically relevant concentrations

N. Absalom, I. McGregor, B. Winters, 2020, Neuropharmacology.

The direct actions of cannabidiol and 2‐arachidonoyl glycerol at GABAA receptors

I. McGregor, J. Arnold, M. Chebib, 2017, Pharmacological research.

Evaluation of the Possible Anticonvulsant Effect of Δ9-Tetrahydrocannabinolic Acid in Murine Seizure Models

I. McGregor, J. Arnold, L. Anderson, 2020, Cannabis and cannabinoid research.

Absence of entourage: Terpenoids commonly found in Cannabis sativa do not modulate the functional activity of Δ9-THC at human CB1and CB2 receptors

I. McGregor, M. Connor, J. Arnold, 2019, bioRxiv.

Cannabidiol potentiates Δ9-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats

I. McGregor, Xu-Feng Huang, J. Arnold, 2011, Psychopharmacology.

The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells.

J. Allen, M. Bebawy, M. Holland, 2006, Biochemical pharmacology.

The schizophrenia susceptibility gene neuregulin 1 modulates tolerance to the effects of cannabinoids.

I. McGregor, J. Micheau, A. Boucher, 2011, The international journal of neuropsychopharmacology.

Female neuregulin 1 heterozygous mice require repeated exposure to Δ⁹-tetrahydrocannabinol to alter sensorimotor gating function.

J. Arnold, T. Karl, T. Chohan, 2013, Pharmacopsychiatry.

The endocannabinoid system impacts seizures in a mouse model of Dravet syndrome

G. Thakur, J. Arnold, J. Kearney, 2021, Neuropharmacology.

The therapeutic potential of the endocannabinoid system for Alzheimer's disease

B. Garner, David Cheng, J. Arnold, 2012, Expert opinion on therapeutic targets.

RESEARCH PAPER Reintoxication: the release of fat-stored D 9 -tetrahydrocannabinol (THC) into blood is enhanced by food deprivation or ACTH exposure

G. Hansen, D. Richardson, J. Arnold, 2009 .

CB_2 and TRPV1 receptors mediate cannabinoid actions on MDR1 expression in multidrug resistant cells

M. Holland, J. Arnold, P. Hone, 2012, Pharmacological reports : PR.

Regulation of fear extinction by long-term depression: The roles of endocannabinoids and brain derived neurotrophic factor

M. Bennett, J. Lagopoulos, S. Hatton, 2017, Behavioural Brain Research.

Interaction of plant cannabinoids with the multidrug transporter ABCC1 (MRP1).

M. Holland, J. Arnold, J. Allen, 2008, European journal of pharmacology.

I. McGregor, N. Lintzeris, Llewellyn Mills, 2020, Accident; analysis and prevention.

Prescribing medicinal cannabis

I. McGregor, T. Nation, J. Arnold, 2020, Australian prescriber.

Cannabinoid Interactions with Cytochrome P450 Drug Metabolism: a Full-Spectrum Characterization

J. Arnold, L. Anderson, L. Oldfield, 2021, The AAPS Journal.

Medical cannabis use in Australia: consumer experiences from the online cannabis as medicine survey 2020 (CAMS-20)

I. McGregor, N. Lintzeris, Llewellyn Mills, 2022, Harm Reduction Journal.

A nutraceutical product, extracted from Cannabis sativa, modulates voltage-gated sodium channel function

S. Petrou, I. McGregor, J. Arnold, 2022, Journal of Cannabis Research.

Pharmacokinetics of Phytocannabinoid Acids and Anticonvulsant Effect of Cannabidiolic Acid in a Mouse Model of Dravet Syndrome.

I. McGregor, J. Arnold, L. Anderson, 2019, Journal of natural products.

Citalopram and Cannabidiol

I. McGregor, M. Berger, G. Amminger, 2021, Journal of clinical psychopharmacology.

Coadministered cannabidiol and clobazam: Preclinical evidence for both pharmacodynamic and pharmacokinetic interactions

N. Absalom, I. McGregor, J. Arnold, 2019, Epilepsia.

Neural correlates of interactions between cannabidiol and Δ9‐tetrahydrocannabinol in mice: implications for medical cannabis

J. Arnold, S. M. Todd, 2015, British journal of pharmacology.

Medical cannabis use in the Australian community following introduction of legal access: the 2018–2019 Online Cross-Sectional Cannabis as Medicine Survey (CAMS-18)

I. McGregor, N. Lintzeris, Llewellyn Mills, 2020, Harm Reduction Journal.

Exercise increases plasma THC concentrations in regular cannabis users.

I. McGregor, K. Rooney, R. Bruno, 2013, Drug and alcohol dependence.

Cannabigerolic acid, a major biosynthetic precursor molecule in cannabis, exhibits divergent effects on seizures in mouse models of epilepsy

N. Absalom, I. McGregor, J. Arnold, 2021, British journal of pharmacology.

Stress-Induced Grey Matter Loss Determined by MRI Is Primarily Due to Loss of Dendrites and Their Synapses

Jonathon C. Arnold, William S. Price, Jim Lagopoulos, 2013, Molecular Neurobiology.

The anticonvulsant phytocannabinoids CBGVA and CBDVA inhibit recombinant T-type channels

C. Bladen, I. McGregor, J. Arnold, 2022, Frontiers in Pharmacology.

Inhibition of human recombinant T‐type calcium channels by phytocannabinoids in vitro

C. Bladen, M. Connor, J. Arnold, 2022, British journal of pharmacology.

Terpenoids Commonly Found in Cannabis sativa Do Not Modulate the Actions of Phytocannabinoids or Endocannabinoids on TRPA1 and TRPV1 Channels

I. McGregor, M. Connor, J. Arnold, 2020, Cannabis and cannabinoid research.

Cannabidiol disrupts conditioned fear expression and cannabidiolic acid reduces trauma-induced anxiety-related behaviour in mice

N. Assareh, J. Arnold, J. Luo, 2020, Behavioural pharmacology.

Cannabidiol for the Treatment of Brain Disorders: Therapeutic Potential and Routes of Administration

H. Chan, J. Arnold, P. Kwok, 2023, Pharmaceutical Research.

The safety and efficacy of low oral doses of cannabidiol: An evaluation of the evidence

I. McGregor, Danielle McCartney, J. Arnold, 2022, Clinical and translational science.

Cannabis constituents interact at the drug efflux pump BCRP to markedly increase plasma cannabidiolic acid concentrations

J. Arnold, L. Anderson, D. Bahceci, 2021, Scientific Reports.

Heterozygous deletion of Gpr55 does not affect a hyperthermia-induced seizure, spontaneous seizures or survival in the Scn1a+/- mouse model of Dravet syndrome

J. Arnold, J. Kearney, L. Anderson, 2023, PloS one.

A Potential Drug-Gene-Drug Interaction Between Cannabidiol, CYP2D6*4, and Fluoxetine: A Case Report.

I. McGregor, T. Nation, J. Arnold, 2022, Journal of clinical psychopharmacology.

Microglial cell hyper-ramification and neuronal dendritic spine loss in the hippocampus and medial prefrontal cortex in a mouse model of PTSD

M. Bennett, J. Lagopoulos, M. Kassem, 2019, Brain, Behavior, and Immunity.

Neuregulin 1 Deficiency Modulates Adolescent Stress-Induced Dendritic Spine Loss in a Brain Region-Specific Manner and Increases Complement 4 Expression in the Hippocampus

M. Bennett, M. Kassem, S. Fok, 2019, Schizophrenia bulletin.

A behavioural comparison of acute and chronic Delta9-tetrahydrocannabinol and cannabidiol in C57BL/6JArc mice.

I. McGregor, Xu-Feng Huang, R. Chesworth, 2010, The international journal of neuropsychopharmacology.

A follow-up study: acute behavioural effects of Δ9-THC in female heterozygous Neuregulin 1 transmembrane domain mutant mice

R. Chesworth, J. Arnold, T. Karl, 2010, Psychopharmacology.

Access to cannabidiol without a prescription: A cross-country comparison and analysis.

I. McGregor, J. Arnold, D. Couch, 2020, The International journal on drug policy.

Dark Classics in Chemical Neuroscience: Δ9-Tetrahydrocannabinol.

M. Glass, I. McGregor, M. Connor, 2019, ACS chemical neuroscience.

Cannabidiol Reduced the Severity of Gastrointestinal Symptoms of Opioid Withdrawal in Male and Female Mice.

J. Arnold, Iain S. McGregor, Bianca B. Wilson, 2022, Cannabis and cannabinoid research.

Absence of Entourage: Terpenoids Commonly Found in Cannabis sativa Do Not Modulate the Functional Activity of Δ9-THC at Human CB1 and CB2 Receptors

I. McGregor, M. Connor, J. Arnold, 2019, bioRxiv.

Disruptive effects of the prototypical cannabinoid &Dgr;9-tetrahydrocannabinol and the fatty acid amide inhibitor URB-597 on go/no-go auditory discrimination performance and olfactory reversal learning in rats

I. McGregor, J. Arnold, G. Hunt, 2011, Behavioural pharmacology.

Adolescent behavioral abnormalities in a Scn1a +/− mouse model of Dravet syndrome

J. Arnold, L. Anderson, D. Bahceci, 2019, Epilepsy & Behavior.

Cannabidiol but not cannabidiolic acid reduces behavioural sensitisation to methamphetamine in rats, at pharmacologically effective doses

I. McGregor, J. Arnold, P. A. Costa, 2022, Psychopharmacology.

Cannabidiol treatment reduces the motivation to self-administer methamphetamine and methamphetamine-primed relapse in rats

I. McGregor, J. Arnold, P. A. Costa, 2018, Journal of psychopharmacology.

In vitro evaluation of the interaction of the cannabis constituents cannabichromene and cannabichromenic acid with ABCG2 and ABCB1.

A. M. George, Peter M. S. Jones, J. Arnold, 2022, European journal of pharmacology.

Functional genomics of epilepsy-associated mutations in the GABAA receptor subunits reveal that one mutation impairs function and two are catastrophic

N. Absalom, I. McGregor, J. Arnold, 2019, The Journal of Biological Chemistry.

Novel molecular changes induced by Nrg1 hypomorphism and Nrg1-cannabinoid interaction in adolescence: a hippocampal proteomic study in mice

I. McGregor, M. Kashem, A. Boucher, 2013, Front. Cell. Neurosci..

Schizophrenia: a consequence of gene-environment interactions?

J. Arnold, T. Karl, 2014, Front. Behav. Neurosci..

Heterozygous neuregulin 1 mice display greater baseline and Δ9-tetrahydrocannabinol-induced c-Fos expression

I. McGregor, J. Micheau, A. Boucher, 2007, Neuroscience.

The yin and yang of cannabis-induced psychosis: the actions of Δ(9)-tetrahydrocannabinol and cannabidiol in rodent models of schizophrenia.

J. Arnold, T. Karl, A. Boucher, 2012, Current pharmaceutical design.

The Differential Binding of Antipsychotic Drugs to the ABC Transporter P-Glycoprotein Predicts Cannabinoid–Antipsychotic Drug Interactions

A. Boucher, Michael P. Kuligowski, J. Arnold, 2017, Neuropsychopharmacology.

Endocannabinoid dysregulation in cognitive and stress-related brain regions in the Nrg1 mouse model of schizophrenia

I. McGregor, J. Arnold, J. Stuart, 2017, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Partial genetic deletion of neuregulin 1 modulates the effects of stress on sensorimotor gating, dendritic morphology, and HPA axis activity in adolescent mice.

M. Bennett, A. Boucher, M. Kassem, 2014, Schizophrenia bulletin.

Heterozygous neuregulin 1 mice are more sensitive to the behavioural effects of Δ9-tetrahydrocannabinol

P. Schofield, J. Micheau, A. Boucher, 2007, Psychopharmacology.

Fasting and exercise increase plasma cannabinoid levels in THC pre-treated rats: an examination of behavioural consequences

I. McGregor, K. Rooney, J. Arnold, 2014, Psychopharmacology.

Genetic deletion of P-glycoprotein alters stress responsivity and increases depression-like behavior, social withdrawal and microglial activation in the hippocampus of female mice

Michael P. Kuligowski, J. Arnold, Kristie Smith, 2017, Brain, Behavior, and Immunity.

A primer on medicinal cannabis safety and potential adverse effects.

J. Arnold, 2021, Australian journal of general practice.

Distinct Neurobehavioural Effects of Cannabidiol in Transmembrane Domain Neuregulin 1 Mutant Mice

I. McGregor, Xu-Feng Huang, R. Chesworth, 2012, PloS one.

Beyond CBD: Inhibitory effects of lesser studied phytocannabinoids on human voltage-gated sodium channels

S. Petrou, I. McGregor, J. Arnold, 2023, Frontiers in Physiology.

The role of endocannabinoid transmission in cocaine addiction

J. Arnold, 2005, Pharmacology Biochemistry and Behavior.

Hyperthermia-Induced Seizures Enhance Brain Concentrations of the Endocannabinoid-Related Linoleoyl Glycerols in a Scn1a+/- Mouse Model of Dravet Syndrome.

J. Arnold, L. Anderson, D. Bahceci, 2022, Cannabis and cannabinoid research.

Sex-specific transcriptomic and epitranscriptomic signatures of PTSD-like fear acquisition

Ira W. Deveson, I. Deveson, I. McGregor, 2021, bioRxiv.

Olivetolic acid, a cannabinoid precursor in Cannabis sativa, but not CBGA methyl ester exhibits a modest anticonvulsant effect in a mouse model of Dravet syndrome

I. McGregor, J. Arnold, L. Anderson, 2022, Journal of Cannabis Research.

Cannabichromene, Related Phytocannabinoids, and 5-Fluoro-cannabichromene Have Anticonvulsant Properties in a Mouse Model of Dravet Syndrome.

I. McGregor, J. Arnold, L. Anderson, 2021, ACS chemical neuroscience.

Randomised controlled trial (RCT) of daily aerobic exercise for inpatient cannabis withdrawal: A study protocol

I. McGregor, K. Rooney, R. Bruno, 2017 .

An Examination of the Anti-Cancer Properties of Plant Cannabinoids in Preclinical Models of Mesothelioma

E. Colvin, I. McGregor, V. Howell, 2022, Cancers.

Cannabichromene and Δ9-Tetrahydrocannabinolic Acid Identified as Lactate Dehydrogenase-A Inhibitors by in Silico and in Vitro Screening.

I. McGregor, J. Krycer, J. Arnold, 2021, Journal of natural products.

The effect of daily aerobic cycling exercise on sleep quality during inpatient cannabis withdrawal: A randomised controlled trial

I. McGregor, K. Rooney, Danielle McCartney, 2020, Journal of sleep research.

Residual social, memory and oxytocin-related changes in rats following repeated exposure to γ-hydroxybutyrate (GHB), 3,4-methylenedioxymethamphetamine (MDMA) or their combination

I. McGregor, J. Arnold, G. Hunt, 2010, Psychopharmacology.

Adolescent Rats Find Repeated Δ9-THC Less Aversive Than Adult Rats but Display Greater Residual Cognitive Deficits and Changes in Hippocampal Protein Expression Following Exposure

I. McGregor, M. Kashem, I. Matsumoto, 2008, Neuropsychopharmacology.

A comparison of Δ9-THC and anandamide induced c-fos expression in the rat forebrain

I. McGregor, A. Topple, J. Arnold, 1998, Brain Research.

Systemically administered oxytocin decreases methamphetamine activation of the subthalamic nucleus and accumbens core and stimulates oxytocinergic neurons in the hypothalamus

A. Guastella, I. McGregor, A. Boucher, 2010, Addiction biology.

Adolescent Oxytocin Exposure Causes Persistent Reductions in Anxiety and Alcohol Consumption and Enhances Sociability in Rats

I. McGregor, D. Carson, J. Arnold, 2011, PloS one.

Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) for chronic insomnia disorder (‘CANSLEEP’ trial): protocol for a randomised, placebo-controlled, double-blinded, proof-of-concept trial

N. Marshall, I. McGregor, C. Irwin, 2020, BMJ Open.

Serotonin (1A) receptor involvement in acute 3,4-methylenedioxymethamphetamine (MDMA) facilitation of social interaction in the rat

I. McGregor, K. Morley, J. Arnold, 2005, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Medicinal cannabis in Australia, 2016: the Cannabis as Medicine Survey (CAMS‐16)

I. McGregor, N. Lintzeris, J. Arnold, 2018, The Medical journal of Australia.

Low-Dose Midazolam Attenuates Predatory Odor Avoidance in Rats

R. Dielenberg, I. McGregor, J. Arnold, 1999, Pharmacology Biochemistry and Behavior.

The distribution of cannabinoid-induced Fos expression in rat brain: differences between the Lewis and Wistar strain

I. McGregor, A. Topple, P. Mallet, 2001, Brain Research.

Stress-Induced Grey Matter Loss Determined by MRI Is Primarily Due to Loss of Dendrites and Their Synapses

M. Bennett, J. Lagopoulos, S. Hatton, 2013, Molecular Neurobiology.

Resilience and reduced c-Fos expression in P2X7 receptor knockout mice exposed to repeated forced swim test

M. Bennett, I. McGregor, M. Kassiou, 2011, Neuroscience.

Prevalence and correlates of cannabis use disorder among Australians using cannabis products to treat a medical condition.

I. McGregor, N. Lintzeris, Llewellyn Mills, 2022, Drug and alcohol review.

Interactions between cannabidiol and Δ9-THC following acute and repeated dosing: Rebound hyperactivity, sensorimotor gating and epigenetic and neuroadaptive changes in the mesolimbic pathway

J. Arnold, Tariq W. Chohan, S. M. Todd, 2017, European Neuropsychopharmacology.

Transmembrane domain Nrg1 mutant mice show altered susceptibility to the neurobehavioural actions of repeated THC exposure in adolescence.

I. McGregor, Xu-Feng Huang, R. Chesworth, 2013, The international journal of neuropsychopharmacology.

The Cannabis Constituent Cannabigerol Does Not Disrupt Fear Memory Processes or Stress-Induced Anxiety in Mice.

N. Assareh, J. Arnold, Cilla Zhou, 2021, Cannabis and Cannabinoid Research.

Fasting and exercise increase plasma cannabinoid levels in THC pre-treated rats: an examination of behavioural consequences

I. McGregor, K. Rooney, J. Arnold, 2014, Psychopharmacology.

The interactive nature of cannabis and schizophrenia risk genes

J. Arnold, T. Karl, 2017 .

Cannabinoids increase conditioned ultrasonic vocalisations and cat odour avoidance in rats: strain differences in drug-induced anxiety.

R. Dielenberg, I. McGregor, J. Arnold, 2010, Life sciences.

Off-target pharmacological profiling of synthetic cannabinoid receptor agonists including AMB-FUBINACA, CUMYL-PINACA, PB-22, and XLR-11

I. McGregor, J. Arnold, S. Banister, 2022, Frontiers in Psychiatry.

Nrg1 deficiency modulates the behavioural effects of prenatal stress in mice

J. Arnold, A. Suraev, Natalia Brzozowska, 2019, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

What does a mouse tell us about neuregulin 1—cannabis interactions?

J. Arnold, T. Karl, 2013, Front. Cell. Neurosci..

In Vitro Screening of Three Commercial Cannabis-Based Products on ATP-Binding Cassette and Solute-Carrier Transporter Function.

M. Bonn-Miller, J. Arnold, L. Anderson, 2020, Cannabis and cannabinoid research.

MEPIRAPIM-derived synthetic cannabinoids inhibit T-type calcium channels with divergent effects on seizures in rodent models of epilepsy

J. Howland, C. Bladen, I. McGregor, 2023, Frontiers in Physiology.

Effects of pre-exposure and co-administration of the cannabinoid receptor agonist CP 55,940 on behavioral sensitization to cocaine.

I. McGregor, A. Topple, J. Arnold, 1998, European journal of pharmacology.

P2X7 receptor knockout mice display less aggressive biting behaviour correlating with increased brain activation in the piriform cortex

M. Bennett, A. Boucher, J. Arnold, 2019, Neuroscience Letters.

Composition and Use of Cannabis Extracts for Childhood Epilepsy in the Australian Community

I. McGregor, N. Lintzeris, J. Arnold, 2018, Scientific Reports.

Editorial: Cannabinoid interactions with ion channels, receptors, and the bio-membrane

P. Ruben, J. Arnold, Mohammad-Reza Ghovanloo, 2023, Frontiers in Physiology.

Chronic treatment with Δ9-tetrahydrocannabinol impairs spatial memory and reduces zif268 expression in the mouse forebrain

N. Mons, J. Micheau, A. Boucher, 2009, Behavioural Pharmacology.