B. Otová

发表

Experimental therapy with 9-[2-(phosphonomethoxy)ethyl]-2,6-diaminopurine (PMEDAP): origin of resistance.

M. Zapotocky, J. Starkova, J. Hanzalová, 2007, Folia biologica.

Reply to ‘Upregulation of asparagine synthetase and cell cycle arrest in t(12;21) positive ALL’ by Stams et al

O. Hrusak, J. Trka, J. Starkova, 2005, Leukemia.

O-Phosphonatomethylcholine, its analogues, alkyl esters, and their biological activity.

D. Emerson, M. Buděšínský, A. Holý, 2001, Journal of medicinal chemistry.

Second-generation taxanes effectively suppress subcutaneous rat lymphoma: role of disposition, transport, metabolism, in vitro potency and expression of angiogenesis genes

P. Souček, R. Vaclavikova, M. Ehrlichová, 2012, Investigational New Drugs.

In vivo modulation of angiogenic gene expression by acyclic nucleoside phosphonates PMEDAP and PMEG.

I. Votruba, A. Holý, B. Otová, 2009, Anticancer research.

Lack of causal relationship between inducibility/severity of adjuvant arthritis in the rat and disease associated changes in production of nitric oxide by macrophages.

B. Otová, Z. Zídek, D. Franková, 1995, Annals of the rheumatic diseases.

Upregulation of asparagine synthetase fails to avert cell cycle arrest induced by L-asparaginase in TEL/AML1-positive leukaemic cells

O. Hrusak, J. Trka, J. Starkova, 2004, Leukemia.

Antitumour activity of N6-substituted PMEDAP derivatives against T-cell lymphoma.

V. Mandys, I. Votruba, A. Holý, 2001, Anticancer research.

Different inhibitory potencies of acyclic phosphonomethoxyalkyl nucleotide analogs toward DNA polymerases alpha, delta and epsilon.

I. Votruba, A. Holý, B. Otová, 1996, Molecular pharmacology.

α Polymerases and a Weak Inhibitor of Rat DNA Tenofovir Diphosphate Is a Poor Substrate

G. Birkuš, B. Otová, M. Hájek, 2014 .

Tenofovir Diphosphate Is a Poor Substrate and a Weak Inhibitor of Rat DNA Polymerases α, δ, and ε*

G. Birkuš, I. Votruba, A. Holý, 2002, Antimicrobial Agents and Chemotherapy.

Antitumor activity of novel purine acyclic nucleotide analogs PMEA and PMEDAP.

I. Votruba, A. Holý, B. Otová, 1997, In Vivo.

Suppression of rat adjuvant arthritis by some acyclic nucleotide analogs.

A. Zidek, A. Holý, B. Otová, 1995, European journal of pharmacology.

9-[2-(phosphonomethoxy)ethyl]adenine diphosphate (PMEApp) as a substrate toward replicative DNA polymerases α, δ, ε, and ε∗

G. Birkuš, I. Votruba, A. Holý, 1999 .

Inhibition of thymidine phosphorylase (PD-ECGF) from SD-lymphoma by phosphonomethoxyalkyl thymines.

I. Votruba, A. Holý, B. Otová, 2005, Biochemical pharmacology.

Relevant animal model of human lymphoblastic leukaemia/lymphoma--spontaneous T-cell lymphomas in an inbred Sprague-Dawley rat strain (SD/Cub).

V. Mandys, J. Damoiseaux, B. Otová, 2002, Folia biologica.

Antimitotic and teratogenic effects of acyclic nucleotide analogues 1-(S)-(3-hydroxy-2-phosphonomethoxyethyl)cytosine (HPMPC) and 9-(2-phosphonomethoxyethyl) adenine (PMEA).

V. Křen, R. Jelinek, A. Holý, 1993, Folia biologica.

Pretreatment of the host cell with 1-(S)-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) is sufficient for its antiviral effect.

I. Votruba, A. Holý, B. Otová, 1992, Acta virologica.

Prevention of acute graft-versus-host disease in rats using 9-(2-phosphonomethoxyethyl) adenine (PMEA).

D. Elleder, V. Křen, M. Elleder, 1993, Folia biologica.

Cytostatic effect of 9-(2-phosphonomethoxyethyl) adenine (PMEA). III. Rat and mouse carcinomas and sarcomas.

V. Křen, I. Votruba, A. Holý, 1993, Folia biologica.

Nonproteolyzed Form of DNA-Polymerase ε from T-Cell Spontaneous Lymphoma of Sprague-Dawley Inbred Rat: Isolation and Characterization

G. Birkuš, I. Votruba, A. Holý, 1998 .

DNA-Polymerases α, δ and ε from T-Cell Spontaneous Lymphoblastic Leukemia of Sprague-Dawley Inbred Rat: Isolation and Characterization

G. Birkuš, I. Votruba, A. Holý, 1995 .

Cytostatic effect of 9-(2-phosphonomethoxyethyl) adenine (PMEA). I. Lymphatic leukemia KHP-Lw-I in Lewis rats.

V. Křen, I. Votruba, A. Holý, 1993, Folia biologica.

Typing of urinary JC virus DNA offers a novel means of tracing human migrations.

M. Al-Ahdal, P. Ondrejka, T. Kitamura, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Slower molecular response to treatment predicts poor outcome in patients with TEL/AML1 positive acute lymphoblastic leukemia

O. Hrusak, J. Zuna, J. Starý, 2003, Cancer.

9-[2-(phosphonomethoxy)ethyl]-2,6-diaminopurine (PMEDAP)--a potential drug against hematological malignancies--induces apoptosis.

I. Votruba, A. Holý, B. Otová, 1999, Anticancer research.

Electron microscopic demonstration of the penetration of liposomes through skin.

B. Otová, J. Schramlová, V. Žižkovský, 1997, Folia biologica.

Characterization of T-cell lymphomas in the Prague inbred Sprague-Dawley/cub rat strain: a model of spontaneous hematologic malignancy.

V. Mandys, J. Damoiseaux, B. Otová, 1999, Transplantation proceedings.

Effects of paclitaxel, docetaxel and their combinations on subcutaneous lymphomas in inbred Sprague-Dawley/Cub rats.

P. Souček, R. Vaclavikova, M. Ehrlichová, 2006, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Antitumour activity of a combined treatment with PMEDAP and docetaxel in the Prague inbred Sprague-Dawley/cub rat strain bearing T-cell lymphoma.

I. Gut, V. Mandys, I. Votruba, 2001, Anticancer Research.

Reply to Stams et al

O. Hrusak, J. Trka, J. Starkova, 2005, Leukemia.

DIFFERENT MECHANISMS IN INHIBITION OF RAT MACROPHAGE NITRIC OXIDE SYNTHASE EXPRESSION BY FK 506 AND CYCLOSPORIN A

K. Mašek, B. Otová, M. Filipec, 2001, Immunopharmacology and immunotoxicology.

Inhibitory effect of FK 506 and cyclosporin A on nitric oxide production by LPS-treated cultured rat macrophages.

B. Otová, M. Filipec, P. Střeštíková, 2000, Physiological Research.

Lackofcausal relationship between inducibility! severity ofadjuvant arthritis intheratanddisease associated changes inproduction ofnitric oxide by macrophages

B. Otová, D. Franková, 1995 .

Electron microscopic demonstration of the interaction of liposomes and cells in vitro.

V. Danielová, B. Otová, J. Holubová, 1997, Folia biologica.