L. Rothem

发表

Antifolate resistance associated with loss of MRP1 expression and function in Chinese hamster ovary cells with markedly impaired export of folate and cholate.

Y. Assaraf, G. Jansen, I. Goldman, 2003, Molecular pharmacology.

Alterations in the Expression of Transcription Factors and the Reduced Folate Carrier as a Novel Mechanism of Antifolate Resistance in Human Leukemia Cells*

Y. Assaraf, A. Aronheim, L. Rothem, 2003, The Journal of Biological Chemistry.

Reduced Folate Carrier Gene Silencing in Multiple Antifolate-resistant Tumor Cell Lines Is Due to a Simultaneous Loss of Function of Multiple Transcription Factors but Not Promoter Methylation*

Y. Assaraf, Lior Mayo, M. Stark, 2004, Journal of Biological Chemistry.

Paraoxonases are associated with intestinal inflammatory diseases and intracellularly localized to the endoplasmic reticulum.

R. Eliakim, R. Shamir, C. Hartman, 2007, Free radical biology & medicine.

Nicotine modulates bone metabolism-associated gene expression in osteoblast cells

R. Eliakim, M. Soudry, L. Rothem, 2009, Journal of Bone and Mineral Metabolism.

Resistance to multiple novel antifolates is mediated via defective drug transport resulting from clustered mutations in the reduced folate carrier gene in human leukaemia cell lines.

Y. Assaraf, D. Priest, G. Jansen, 2002, The Biochemical journal.

Loss of folylpoly‐γ‐glutamate synthetase activity is a dominant mechanism of resistance to polyglutamylation‐dependent novel antifolates in multiple human leukemia sublines

Y. Assaraf, G. Jansen, Clyde A. Smith, 2003, International journal of cancer.

The Reduced Folate Carrier Gene Is a Novel Selectable Marker for Recombinant Protein Overexpression

Y. Assaraf, G. Jansen, M. Stark, 2005, Molecular Pharmacology.

Coexistence of multiple mechanisms of PT523 resistance in human leukemia cells harboring 3 reduced folate carrier alleles: transcriptional silencing, inactivating mutations, and allele loss.

Y. Assaraf, G. Jansen, I. Ifergan, 2006, Blood.

inactivating mutations and allele loss leukemia cells harboring three reduced folate carrier alleles : Coexistence of multiple mechanisms of PT 523-resistance in human

Y. Assaraf, G. Jansen, I. Ifergan, 2005 .

Intraoperative Fracture of the Femur in Revision Total Hip Arthroplasty with a Fully HA-Coated Stem

A. Lerner, Tal Salamon, R. Hiscock, 2014 .

Expression, purification, and properties of ADP-ribosylation factor (ARF) GTPase activating protein-1.

E. Cukierman, M. Rotman, D. Cassel, 2001, Methods in enzymology.

Nicotinic modulation of gene expression in osteoblast cells, MG-63.

R. Eliakim, M. Soudry, L. Rothem, 2011, Bone.

Loss of Multidrug Resistance Protein 1 Expression and Folate Efflux Activity Results in a Highly Concentrative Folate Transport in Human Leukemia Cells*

G. Peters, B. Dijkmans, Y. Assaraf, 2003, The Journal of Biological Chemistry.

Oral Insulin Up-regulates Toll-like Receptor 4 Expression and Enhances Intestinal Recovery Following Lipopolysaccharide-induced Gut Injury in a Rat

R. Shamir, N. Shehadeh, I. Sukhotnik, 2007, Digestive Diseases and Sciences.

Disparate mechanisms of antifolate resistance provoked by methotrexate and its metabolite 7-hydroxymethotrexate in leukemia cells: implications for efficacy of methotrexate therapy.

G. Peters, Y. Assaraf, G. Jansen, 2004, Blood.

cells: implications for efficacy of methotrexate therapy methotrexate and its metabolite 7-hydroxymethotrexate in leukemia Disparate mechanisms of antifolate resistance provoked by

G. Peters, Y. Assaraf, G. Jansen, 2013 .

Impaired CREB-1 Phosphorylation in Antifolate-Resistant Cell Lines with Down-Regulation of the Reduced Folate Carrier Gene

Y. Assaraf, M. Stark, L. Rothem, 2004, Molecular Pharmacology.

but Not Promoter Methylation Function of Multiple Transcription Factors Lines Is Due to a Simultaneous Loss of Multiple Antifolate-resistant Tumor Cell Reduced Folate Carrier Gene Silencing in Recombination:

Y. Assaraf, M. Stark, L. Rothem, 2014 .

silencing, inactivating mutations, and allele loss leukemia cells harboring 3 reduced folate carrier alleles: transcriptional Coexistence of multiple mechanisms of PT523 resistance in human

Y. Assaraf, G. Jansen, I. Ifergan, 2013 .