Xiaoyun Fu

发表

Oxidative modification of von Willebrand factor by neutrophil oxidants inhibits its cleavage by ADAMTS13.

Junmei Chen, José A López, Xiaoyun Fu, 2010, Blood.

Hypochlorous Acid Converts the γ-Glutamyl Group of Glutathione Disulfide to 5-Hydroxybutyrolactam, a Potential Marker for Neutrophil Activation*

W. Yuan, J. Heinecke, Xiaoyun Fu, 2009, The Journal of Biological Chemistry.

Tyrosine 192 in Apolipoprotein A-I Is the Major Site of Nitration and Chlorination by Myeloperoxidase, but Only Chlorination Markedly Impairs ABCA1-dependent Cholesterol Transport*

J. Voss, J. Heinecke, P. Green, 2005, Journal of Biological Chemistry.

Methionine Sulfoxide and Proteolytic Cleavage Contribute to the Inactivation of Cathepsin G by Hypochlorous Acid

C. Verlinde, J. Heinecke, Xiaoyun Fu, 2005, Journal of Biological Chemistry.

Lysine Residues Direct the Chlorination of Tyrosines in YXXK Motifs of Apolipoprotein A-I When Hypochlorous Acid Oxidizes High Density Lipoprotein*

J. Heinecke, Xiaoyun Fu, J. Kao, 2004, Journal of Biological Chemistry.

Hypochlorous Acid Generated by Neutrophils Inactivates ADAMTS13

Junmei Chen, José A López, Xiaoyun Fu, 2014, The Journal of Biological Chemistry.

Heterogeneity of blood processing and storage additives in different centers impacts stored red blood cell metabolism as much as storage time: lessons from REDS‐III—Omics

Mars Stone, Xiaoyun Fu, Tamir Kanias, 2018, Transfusion.

N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice.

J. Moake, L. Nolasco, Junmei Chen, 2011, The Journal of clinical investigation.

Post-translational oxidative modification of fibrinogen is associated with coagulopathy after traumatic injury.

K. Ward, C. Wade, D. Brophy, 2016, Free radical biology & medicine.

Myeloperoxidase Impairs ABCA1-dependent Cholesterol Efflux through Methionine Oxidation and Site-specific Tyrosine Chlorination of Apolipoprotein A-I*

N. Brot, J. Heinecke, P. Green, 2006, Journal of Biological Chemistry.

A Pilot Study of High-Dose N-Acetylcysteine Infusion in Patients with Sickle Cell Disease

Junmei Chen, B. Konkle, S. Cate, 2016 .

Genome-Wide Characterization and Expression Analysis of HD-ZIP Gene Family in Dendrobium officinale

G. Zhou, Xiao Han, Jun Zhang, 2022, Frontiers in Genetics.

The biological activity of FasL in human and mouse lungs is determined by the structure of its stalk region.

N. Brot, N. Hagimoto, T. Martin, 2011, The Journal of clinical investigation.

Deficiency of Superoxide Dismutase Impairs Protein C Activation and Enhances Susceptibility to Experimental Thrombosis

S. Lentz, S. Dayal, K. Wilson, 2015, Arteriosclerosis, thrombosis, and vascular biology.

Ethyl glucuronide, a marker of alcohol consumption, correlates with metabolic markers of oxidant stress but not with hemolysis in stored red blood cells from healthy blood donors

S. Kleinman, A. D’Alessandro, M. Busch, 2020, Transfusion.

Nicotine exposure increases markers of oxidant stress in stored red blood cells from healthy donor volunteers

G. Page, S. Kleinman, A. D’Alessandro, 2020, Transfusion.

Stored RBC metabolism as a function of caffeine levels

G. Page, S. Kleinman, A. D’Alessandro, 2020, Transfusion.

NADPH Oxidase Restrains the Matrix Metalloproteinase Activity of Macrophages*

S. Shapiro, W. Parks, W. Liles, 2005, Journal of Biological Chemistry.

Oxidative Cross-linking of Tryptophan to Glycine Restrains Matrix Metalloproteinase Activity

R. Mecham, W. Parks, J. Heinecke, 2004, Journal of Biological Chemistry.

Specific sequence motifs direct the oxygenation and chlorination of tryptophan by myeloperoxidase.

R. Mecham, W. Parks, J. Heinecke, 2006, Biochemistry.

High-density lipoprotein modulates thrombosis by preventing von Willebrand factor self-association and subsequent platelet adhesion.

Junmei Chen, B. Konkle, T. Martin, 2016, Blood.

Fatty acid desaturase activity in mature red blood cells and implications for blood storage quality

S. Kleinman, P. Buehler, A. D’Alessandro, 2021, Transfusion.

Correlation Between Red Blood Cell Survival and Cytochrome P450 1A2 Enzyme Activity

J. Zimring, G. Tsongalis, J. Roback, 2013 .

Reexamination of the chromium‐51–labeled posttransfusion red blood cell recovery method

E. Hod, A. D’Alessandro, A. Mintz, 2019, Transfusion.

Impact of taurine on red blood cell metabolism and implications for blood storage

S. Kleinman, A. D’Alessandro, M. Busch, 2020, Transfusion.

Differences in Steap3 expression are a mechanism of genetic variation of RBC storage and oxidative damage in mice.

A. D’Alessandro, H. Howie, J. Zimring, 2019, Blood advances.

Acrolein Impairs ATP Binding Cassette Transporter A1-dependent Cholesterol Export from Cells through Site-specific Modification of Apolipoprotein A-I*

T. McDonald, K. Uchida, J. Heinecke, 2005, Journal of Biological Chemistry.

Acrolein Modifies Apolipoprotein A‐I in the Human Artery Wall

T. McDonald, K. Uchida, J. Heinecke, 2005, Annals of the New York Academy of Sciences.

The lysophospholipid‐binding molecule CD1D is not required for the alloimmunization response to fresh or stored RBCs in mice despite RBC storage driving alterations in lysophospholipids

C. J. Luckey, J. Zimring, Xiaoyun Fu, 2021, Transfusion.

Donor sex, age and ethnicity impact stored red blood cell antioxidant metabolism through mechanisms in part explained by glucose 6-phosphate dehydrogenase levels and activity

Marion C Lanteri, M. Gladwin, G. Page, 2020, Haematologica.

Unique Proteomic Signatures Distinguish Macrophages and Dendritic Cells

K. Bornfeldt, W. Yuan, N. Pamir, 2012, PloS one.

Arterial Platelet Adhesion in Atherosclerosis‐Prone Arteries of Obese, Insulin‐Resistant Nonhuman Primates

G. Shaw, Junmei Chen, J. Lindner, 2021, Journal of the American Heart Association.

Acrolein Impairs ABCA 1-dependent Cholesterol Export from Cells through Site-Specific Modification of Apolipoprotein A-I

T. McDonald, K. Uchida, J. Heinecke, 2005 .

Generation of intramolecular and intermolecular sulfenamides, sulfinamides, and sulfonamides by hypochlorous acid: a potential pathway for oxidative cross-linking of low-density lipoprotein by myeloperoxidase.

J. Heinecke, Xiaoyun Fu, D. Mueller, 2002, Biochemistry.

Hematologic and systemic metabolic alterations due to Mediterranean class II G6PD deficiency in mice

E. Hod, A. D’Alessandro, H. Howie, 2021, JCI insight.

Deuterated Linoleic Acid Attenuates the RBC Storage Lesion in a Mouse Model of Poor RBC Storage

M. Shchepinov, P. Buehler, E. Hod, 2022, Frontiers in Physiology.

Deletion of 12-lipoxygenase normalizes platelet function after storage and transfusion in thrombocytopenic mice

M. Holinstat, Xiaoyun Fu, M. Stolla, 2022, bioRxiv.

Hypochlorous Acid Oxygenates the Cysteine Switch Domain of Pro-matrilysin (MMP-7)

W. Parks, J. Heinecke, S. Kassim, 2001, The Journal of Biological Chemistry.

Addition of ascorbic acid solution to stored murine red blood cells increases posttransfusion recovery and decreases microparticles and alloimmunization

S. Stowell, A. Palmer, J. Zimring, 2013, Transfusion.

Involvement of annexin A1 in multidrug resistance of K562/ADR cells identified by the proteomic study.

S. Zeng, Xiaoyun Fu, Jiang Cao, 2009, Omics : a journal of integrative biology.

LC-MS/MS-MRM-Based Targeted Metabolomics for Quantitative Analysis of Polyunsaturated Fatty Acids and Oxylipins.

J. Zimring, Xiaoyun Fu, Yi Wang, 2019, Methods in molecular biology.

Simultaneous Exposure of Sites in von Willebrand Factor for Glycoprotein Ib Binding and ADAMTS13 Cleavage: Studies With Ristocetin

Junmei Chen, José A López, Xiaoyun Fu, 2012, Arteriosclerosis, thrombosis, and vascular biology.

The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport.

A. Chait, S. Pennathur, J. Brunzell, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Bcl-xL Deamidation Is a Critical Switch in the Regulation of the Response to DNA Damage

Ellen M. Langer, Benjamin E. Deverman, E. Langer, 2002, Cell.

Hematologic and systemic metabolic alterations due to Mediterranean type II G6PD deficiency in mice

E. Hod, A. D’Alessandro, H. Howie, 2021, bioRxiv.

The clinical impact of glucose-6-phosphate dehydrogenase deficiency in patients with sickle cell disease

E. Hod, A. D’Alessandro, J. Zimring, 2018, Current opinion in hematology.

Methionine oxidation contributes to bacterial killing by the myeloperoxidase system of neutrophils

N. Brot, J. Heinecke, H. Rosen, 2009, Proceedings of the National Academy of Sciences.

Fibrin clot structure and mechanics associated with specific oxidation of methionine residues in fibrinogen.

K. Weigandt, Xiaoyun Fu, Yi Wang, 2012, Biophysical journal.

Hypochlorous Acid Generated by Myeloperoxidase Modifies Adjacent Tryptophan and Glycine Residues in the Catalytic Domain of Matrix Metalloproteinase-7 (Matrilysin)

W. Parks, J. Heinecke, S. Kassim, 2003, Journal of Biological Chemistry.

Metabolites in stored platelets associated with platelet recoveries and survivals

J. Zimring, S. Slichter, Xiaoyun Fu, 2016, Transfusion.

Myeloperoxidase Inactivates TIMP-1 by Oxidizing Its N-terminal Cysteine Residue

D. Madtes, T. Martin, J. Heinecke, 2007, Journal of Biological Chemistry.

Piperlongumine Blocks JAK2-STAT3 to Inhibit Collagen-Induced Platelet Reactivity Independent of Reactive Oxygen Species†

D. Tweardy, K. Hull, D. Romo, 2015, PloS one.

Shear stress-induced unfolding of VWF accelerates oxidation of key methionine residues in the A1A2A3 region.

Junmei Chen, José A López, Ying Zheng, 2010, Blood.

Cysteine Disulfides (Cys-ss-X) as Sensitive Plasma Biomarkers of Oxidative Stress

Junmei Chen, B. Konkle, José A López, 2019, Scientific Reports.

Mapping the lung proteome in cystic fibrosis.

S. Gharib, T. Vaisar, J. Heinecke, 2009, Journal of proteome research.

Spectral index for assessment of differential protein expression in shotgun proteomics.

Xiaoyun Fu, S. Gharib, T. Vaisar, 2008, Journal of proteome research.

Cysteine Disulfides (Cys-ss-X) as Sensitive Plasma Biomarkers of Oxidative Stress

Junmei Chen, B. Konkle, Xiaoyun Fu, 2019, Scientific Reports.

Decellularized Human Kidney Cortex Hydrogels Enhance Kidney Microvascular Endothelial Cell Maturation and Quiescence.

W. Zeng, J. Himmelfarb, Ryan J. Nagao, 2016, Tissue engineering. Part A.

Bioactive lipids accumulate in stored red blood cells despite leukoreduction: a targeted metabolomics study

Xiaoyun Fu, Katherine Odem-Davis, J. Zimring, 2016, Transfusion.

Activation and silencing of matrix metalloproteinases.

W. Parks, J. Heinecke, Xiaoyun Fu, 2008, Seminars in cell & developmental biology.

Piloting and implementation of quality assessment and quality control procedures in RBC‐Omics: a large multi‐center study of red blood cell hemolysis during storage

Grier P Page, Sonia Bakkour, Dylan Hampton, 2019, Transfusion.

The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport.

A. Chait, S. Pennathur, J. Brunzell, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Resolution of translation start site for the human Kell glycoprotein

J. Zimring, Xiaoyun Fu, Grady R. Blacken, 2013, Transfusion.